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Boston Scientific Initiates AVANT GUARD Clinical Trial to Evaluate FARAPULSE Pulsed Field Ablation System as First-Line Treatment for Persistent Atrial Fibrillation

DAIC

Outcomes of ablation with the FARAPULSE PFA System – a nonthermal treatment in which electric fields selectively ablate heart tissue – will be compared to outcomes following use of anti-arrhythmic drug (AAD) therapy, which is commonly prescribed for patients living with persistent AF. Circulation. Not available for sale.

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Personalized Heart Digital Twins Detect Substrate Abnormalities in Scar-Dependent Ventricular Tachycardia

Circulation

Circulation, Ahead of Print. BACKGROUND:Current outcomes from catheter ablation for scar-dependent ventricular tachycardia (VT) are limited by high recurrence rates and long procedure durations. Predicted optimum ablation sites to terminate all VTs in the models were identified.

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Different Incidence and Size of Silent Strokes After Pulsed Field Ablation With Circular Shaped Ablation Catheters

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print.

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Long-Term Durability of High- and Very High-Power Short-Duration PVI by Invasive Remapping: The HPSD Remap Study

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:High-power short-duration ablation has shown impressive efficacy and safety for pulmonary vein isolation (PVI); however, initial efficacy results with very high power short-duration ablation were discouraging. rates between 90W and 50W.

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Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1

Circulation

Circulation, Ahead of Print. Using a battery of assays, including immunohistochemistry, immuno-electron microscopy imaging, and action potential recording, we assessed the effect of loss ofCarm1function on cardiomyocyte cell growth, myofibril expansion, T-tubule formation, and electrophysiological maturation.

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Coronary Involvement With Pulsed Field Ablation and Radiofrequency Ablation: Preclinical Insights

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print.

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Ablating the Limits: Catheter Ablation of Ventricular Tachycardia in Cardiac Amyloid Patients

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print.