Ablation, Cardiac Function and Ischemia

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Ablation

Cardiac Function

Ischemia

CRISPR-Cas9 base editing of pathogenic CaMKII? improves cardiac function in a humanized mouse model

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ) is a prominent inducer of various cardiac disorders, which is mediated by 2 oxidation-sensitive methionine residues within the regulatory domain. Here, we extended this therapeutic concept toward potential clinical translation.

Cardiac Function

Cardiac Function Exercise Ischemia Cardiovascular Disease

What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

JULY 21, 2024

Cardiac function is poor, with akinesis of the LAD territory. There is no definite evidence of acute ischemia. (ie, Simply stated — t he patient was having recurrent PMVT without Q Tc prolongation, and without evidence of ongoing transmural ischemia. ( Some residual ischemia in the infarct border might still be present.

Arrhythmia

Arrhythmia Cardiogenic Shock Bradycardia Defibrillator

Cardiovascular Update

CRISPR-Cas9 base editing of pathogenic CaMKII? improves cardiac function in a humanized mouse model

What are treatment options for this rhythm, when all else fails?

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