HeartRhythm

JANUARY 27, 2025

The results of pulmonary vein isolation are limited by arrhythmia recurrence, which is most often due to a failure to effectuate a durable contiguous circumferential transmural lesion around the pulmonary vein (PV) ostia.

Pulmonary 40

Pulmonary Ablation Arrhythmia 40

HeartRhythm

MARCH 31, 2025

Whilst pulmonary vein isolation (PVI) is the key endpoint for catheter ablation therapy for atrial fibrillation (AF), it is unknown whether adjunctive carinal ablation impacts outcome beyond achieving first pass isolation.

Atrial Fibrillation 40

Atrial Fibrillation Pulmonary Ablation Arrhythmia 40

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Background Catheter ablation (CA) for symptomatic atrial fibrillation (AF) offers the best outcomes for patients. Despite the benefits of CA, a significant proportion of patients suffer a recurrence; hence, there is scope to potentially improve outcomes through technical innovations such as ablation index (AI) guidance during AF ablation.

Ablation 64

Ablation Atrial Fibrillation BMI Arrhythmia 64

HeartRhythm

MARCH 31, 2025

Radiofrequency catheter ablation (RFCA) for persistent atrial fibrillation (AF) is associated with suboptimal long-term outcomes. Although increasing evidence supports substrate-based ablation strategies targeting extra-PV sources, reliable endpoints during CA beyond pulmonary vein (PV) isolation are not well established.

Pulmonary 40

Pulmonary Ablation Atrial Fibrillation Tachycardia 40

HeartRhythm

JANUARY 7, 2025

Patients with D-transposition of the great arteries (D-TGA) palliated with atrial switch often develop atrial arrhythmias (AA) requiring pulmonary venous atrium (PVA) access for ablation, which can be achieved via retrograde aortic approach (RAA) or trans-baffle access (TBA).13

Arrhythmia 45

Arrhythmia Aortic Ablation Pulmonary 45

HeartRhythm

MARCH 31, 2025

The AP Fontan operation and the total cavo-pulmonary connection (TCPC) have revolutionised the surgical treatment of patients with functionally univentricular hearts. However, post-surgical arrhythmias contribute considerably to morbidity and mortality and can be difficult to manage.

Arrhythmia 40

Arrhythmia Technology Ablation Pulmonary 40

HeartRhythm

MARCH 31, 2025

Pulsed field ablation (PFA) is a promising new alternative to thermal ablation (TA) for atrial fibrillation (AF), improving safety and duration of procedure times. While pulmonary vein isolation (PVI) durability appears comparable between PFA and TA, the necessity of post-ablation remapping remains uncertain.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Arrhythmia Pulmonary 40

HeartRhythm

MARCH 31, 2025

Pulsed field ablation (PFA) has emerged as a new ablation method for treating atrial fibrillation (AF) through pulmonary vein isolation (PVI).

Ablation 40

Ablation Atrial Fibrillation Arrhythmia Technology 40

HeartRhythm

MARCH 31, 2025

Large footprint pulse field ablation (PFA) catheters have been widely adopted for pulmonary vein isolation (PVI) and posterior wall isolation (PWI) for atrial fibrillation. The role of large footprint PFA catheters for linear ablation in the treatment of organized atrial arrhythmias has not been well described.

Ablation 40

Ablation Atrial Fibrillation Pulmonary Arrhythmia 40

Journal of Cardiovascular Electrophysiology

DECEMBER 10, 2024

Pulsed field ablation (PFA) may overcome the disadvantages of thermal energy and improve both ablation efficacy and safety. Objective We report the feasibility, safety, and clinical efficacy of focal monopolar PFA in patients with the origin of their atrial arrhythmia in the SVC.

Arrhythmia 40

Arrhythmia Ablation Pulmonary Tachycardia 40

HeartRhythm

MARCH 31, 2025

Catheter ablation via pulmonary vein isolation (PVI) is first-line treatment for paroxysmal atrial fibrillation (pAF). It is unclear whether additional lesions with PVI using the novel pulsed field ablation (PFA) technique affects outcomes in this population.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Arrhythmia Pulmonary 40

HeartRhythm

MARCH 31, 2025

Persistent atrial fibrillation (AF) ablation targeting extra-pulmonary vein drivers using various technologies has delivered varying results from no benefit to significant arrhythmia free survival.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Pulmonary Technology 40

HeartRhythm

APRIL 16, 2025

Catheter ablation for atrial fibrillation (AF) aims to achieve durable pulmonary vein isolation (PVI) by creating transmural lesions that disrupt arrhythmogenic pathways. However, consistent and lasting success remains challenging due to variability in lesion formation and durability, contributing to arrhythmia recurrence.

Ablation 40

Ablation Atrial Fibrillation Pulmonary Arrhythmia 40

European Journal of Heart Failure

FEBRUARY 25, 2025

Overview of the study population and effects observed after catheter ablation for atrial fibrillation. PVI, pulmonary vein isolation. Herein we describe the effects of catheter ablation on AF burden, arrhythmia recurrences, and ventricular function in end-stage HF. to 39.18.3% ( p <0.001) following ablation.

Atrial Fibrillation 40

Atrial Fibrillation Heart Failure Ablation Arrhythmia 40

HeartRhythm

APRIL 30, 2024

Despite advances, catheter ablation success rates for persistent AF remain at 50-60%. The approach for recurrent persistent AF, beyond pulmonary vein isolation, remains contentious. Surgical maze procedures have demonstrated superior outcomes compared to catheter ablation.

Ablation 40

Ablation Arrhythmia Pulmonary Outcomes 40

Journal of Cardiovascular Electrophysiology

DECEMBER 7, 2023

Abstract Background The newly introduced nonthermal pulsed field ablation (PFA) is a promising technology to achieve fast pulmonary vein isolation (PVI) with high acute success rates and good safety features. Data comparing PFA to VHPSD-PVI is lacking. For PFA-PVI a pentaspline 20 electrode catheter was used.

Ablation 40

Ablation Pulmonary Arrhythmia Atrial Fibrillation 40

Journal of Cardiovascular Electrophysiology

MARCH 27, 2025

ABSTRACT Background Ultra-low temperature cryoablation (ULTC) is a technique designed to rapidly cool cardiac tissue to extremely low temperatures, enabling the creation of ablation lesions for the treatment of atrial fibrillation (AF). Arrhythmia outcomes after repeat ablation were evaluated.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Arrhythmia Bicuspid/Mitral 40

Journal of Cardiovascular Electrophysiology

OCTOBER 19, 2023

Abstract The QDOT MICRO™ Catheter is a novel open-irrigated contact force-sensing radiofrequency ablation catheter. It offers very high-power short-duration (vHPSD) ablation with 90 W for 4 s to improve safety and efficacy of catheter ablation procedures.

Arrhythmia 40

Arrhythmia Ablation Atrial Flutter Atrial Fibrillation 40

HeartRhythm

MARCH 31, 2025

Given the rapid adoption of pulse field ablation (PFA), there is interest in uses beyond pulmonary vein isolation. Here, we describe a case of incessant atrial tachycardia (AT), in which PFA resulted in short-term arrhythmia suppression but tachycardia recurred and lesion size regressed on interval mapping.

Ablation 40

Ablation Tachycardia Pulmonary Arrhythmia 40

HeartRhythm

MARCH 31, 2025

Despite advances in treatment of atrial fibrillation (AF) with pulmonary vein isolation (PVI), AF recurrence remains a challenge. High tx burden pre-PVI may lead to difficulty maintaining arrhythmia freedom post-PVI.

Atrial Fibrillation 40

Atrial Fibrillation Pulmonary Arrhythmia Ablation 40

HeartRhythm

APRIL 30, 2024

Animal studies suggest that catheter ablation-associated parasympathetic and sympathetic denervation could result in increased ventricular arrhythmias (VA). The impact of catheter ablation of atrial fibrillation on VA burden in humans has not been assessed.

Atrial Fibrillation 40

Atrial Fibrillation Arrhythmia Ablation Pulmonary 40

Circulation: Arrhythmia and Electrophysiology

DECEMBER 19, 2024

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. We investigate whether additional linear ablation from the superior vena cava to the right atrial septum and cavotricuspid isthmus ablation improves the rhythm outcome of patients with persistent AF undergoing cryoballoon PVI (Cryo-PVI).METHODS:In

Atrial Fibrillation 40

Atrial Fibrillation Ablation Pulmonary Arrhythmia 40

Circulation: Arrhythmia and Electrophysiology

JANUARY 29, 2024

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:High-power short-duration ablation has shown impressive efficacy and safety for pulmonary vein isolation (PVI); however, initial efficacy results with very high power short-duration ablation were discouraging. No complications occurred.

Electrophysiology 76

Electrophysiology Pulmonary Atrial Fibrillation Arrhythmia 76

All About Cardiovascular System and Disorders

MAY 18, 2024

Pulsed Field Ablation is a relatively new modality for treatment of atrial fibrillation. In conventional ablation for atrial fibrillation, either heating of tissue is produced by radiofrequency application or freezing of tissues by cryoablation. Pulsed field ablation group had 305 patients while thermal ablation group had 302 patients.

Ablation 40

Ablation Atrial Fibrillation Pulmonary Arrhythmia 40

Dr. S. Venkatesan MD

APRIL 28, 2024

Both atria develop from a combination of the primitive atrium, sinus venous, and pulmonary veins.It Spatial relationship of sites for atrial fibrillation drivers and atrial tachycardia in patients with both arrhythmias July 2017 International Journal of Cardiology 248(3) AF begets AF. Let us see few factors.

Atrial Fibrillation 75

Atrial Fibrillation Bicuspid/Mitral Pulmonary Ablation 75

HeartRhythm

NOVEMBER 27, 2023

Pulsed field ablation (PFA) is a nonthermal energy source for ablation of cardiac arrhythmias. This study investigated the prospective outcomes of a novel PFA generator in conjunction with a commercially available, contact force-sensing, focal ablation catheter.

Ablation 40

Ablation Pulmonary Arrhythmia Outcomes 40

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

Backgroundwide antral pulmonary vein isolation (PVI) is effective for treating paroxysmal atrial fibrillation (PAF), although time-demanding. Procedural data and electrophysiology (EP) laboratory times were systematically collected and analyzed.

Atrial Fibrillation 52

Atrial Fibrillation Ablation Laboratory Electrophysiology 52

HeartRhythm

JULY 30, 2024

Extra-pulmonary vein (PV) triggers have been reported in up to 4.9-15% 15% of all atrial fibrillation (AF) patients who undergo catheter ablation and plays significant roles in arrhythmia recurrence.1,2 Extra-pulmonary vein (PV) triggers have been reported in up to 4.9-15%

Aneurysm 40

Aneurysm Ablation Atrial Fibrillation Pulmonary 40

Open Heart

JANUARY 18, 2024

Introduction Three recent randomised controlled trials have demonstrated that pulmonary vein isolation as an initial rhythm control strategy with cryoablation reduces atrial arrhythmia recurrence in patients with symptomatic paroxysmal atrial fibrillation (PAF) compared with antiarrhythmic drug (AAD) therapy. ablations over a lifetime.

Atrial Fibrillation 69

Atrial Fibrillation Ablation Pulmonary Arrhythmia 69

Journal of Cardiovascular Electrophysiology

APRIL 2, 2025

The Kaplan-Meier curve of all-atrial arrhythmia-free survival for (A) all persistent patients and (B) patients who underwent PSM conducted to the higher recurrence rate in PVI + group. Conclusions PVI plus extra PV ablation using a pentaspline PFA catheter is associated with a higher incidence of atrial tachycardia recurrences.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Tachycardia Tricuspid 40

HeartRhythm

JULY 14, 2024

Pulsed field ablation (PFA) has become increasingly important in the treatment of cardiac arrhythmias. In addition to single-shot devices mainly used for pulmonary vein isolation, focal PFA may provide a treatment option that increases the versatility of the technique.

Ablation 40

Ablation Tachycardia Pulmonary Arrhythmia 40

Circulation: Arrhythmia and Electrophysiology

DECEMBER 16, 2024

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Patients were randomly assigned to either the PVI+SVC ablation group or the PVI-only group. CONCLUSIONS:The addition of SVC ablation to PVI did not enhance freedom from atrial tachyarrhythmia at 12 months, and it led to increased complications. versus 72%;P=0.41).

Ablation 40

Ablation Atrial Fibrillation Electrophysiology Pulmonary 40

HeartRhythm

MARCH 31, 2025

Identifying nearfield and farfield signals is critical to mapping and ablating cardiac arrhythmias. This assessment is qualitative, depending on the sharpness of electrograms. Electrogram peak frequency (PF) is hypothesized to be a quantitative measure of signal proximity.

Pulmonary 40

Pulmonary Arrhythmia Ablation 40

Circulation: Arrhythmia and Electrophysiology

NOVEMBER 3, 2023

Circulation: Arrhythmia and Electrophysiology, Volume 16, Issue 11 , Page e012043, November 1, 2023. BACKGROUND:In patients with persistent atrial fibrillation (PersAF), catheter ablation aiming for pulmonary vein isolation (PVI) is associated with moderate clinical effectiveness.

Atrial Fibrillation 40

Atrial Fibrillation Pulmonary Quality of Life Ablation 40

Circulation: Arrhythmia and Electrophysiology

NOVEMBER 23, 2023

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Background:Pulsed field ablation (PFA) has emerged as an alternative to radiofrequency ablation. A contact force–sensing catheter was used to focally deliver PFA/radiofrequency at the pulmonary veins and other predefined sites in the atria.

Ablation 40

Ablation Pulmonary Atrial Fibrillation Electrophysiology 40

Journal of Cardiovascular Electrophysiology

NOVEMBER 21, 2023

In this large substudy of the AWARE Trial, a high-power short-duration (HPSD) radiofrequency ablation strategy was found to be similarly effective as a low-power long-duration strategy with no difference in time to first recurrence of any AF lasting ≥30 s. Methods Patients were grouped according to a HPSD (≥40 W) or LPLD (≤35 W) strategy.

Ablation 40

Ablation Pulmonary Atrial Fibrillation Arrhythmia 40

DAIC

DECEMBER 26, 2023

a company primarily focused on leveraging its novel and proprietary CellFX Nanosecond Pulsed Field Ablation (nsPFA) technology for the treatment of atrial fibrillation, announced the completion of the first five procedures in its first-in-human feasibility study with its novel CellFX nsPFA cardiac catheter.

Ablation 59

Ablation Atrial Fibrillation Technology Hospital 59