Physiologically Speaking

DECEMBER 17, 2024

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. This has raised concerns that long-term, high-volume exercise might be detrimental to heart health.

Risk Factors 99

Risk Factors Genetic predisposition Plaque Exercise 99

Medical Xpress - Cardiology

DECEMBER 19, 2024

We sing about how Christmas brings "tidings of comfort and joy," but the holiday also brings something not so "merry and bright.

Heart Attack 110

Heart Attack Heart attacks 110

Med Page Today

DECEMBER 18, 2024

(MedPage Today) -- Moderate wine consumption maintained its association with cardiovascular benefit when self-reports were taken out of the equation, the large PREDIMED trial showed. Using urinary tartaric acid as an objective biomarker measuring.

Biomarkers 98

Biomarkers 98

Science Daily - Stroke

DECEMBER 18, 2024

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.

Diet 83

Diet Biomarkers 83

Journal of Clinical Investigation - Cardiology

DECEMBER 16, 2024

Aging negatively affects the capacity of muscle stem cells (MuSCs) to regenerate muscle. In this issue of the JCI, Ancel, Michaud, and colleagues used a high-content imaging screen to identify nicotinamide and pyridoxine as promoters of MuSC function. The combination of the two compounds promoted MuSC function in vivo in aged mice and in primary cells isolated from older individuals.

Circulation 95

Circulation 95

HCPLive

DECEMBER 16, 2024

In this episode, hosts reflect on the advancement in CGM that reshaped care for diabetes and overall health during 2024.

Diabetes 81

Diabetes 81

Medical Xpress - Cardiology

DECEMBER 20, 2024

Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.

Research 107

Research 107

Science Daily - Heart Disease

DECEMBER 16, 2024

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.

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Atrial Fibrillation Myocardial Infarction Kidney Disease Dementia 76

Journal of Clinical Investigation - Cardiology

DECEMBER 16, 2024

Despite the impressive clinical benefits and widespread adoption of sodium glucose cotransporter 2 inhibitors (SGLT2i) to treat all classes of heart failure, their cardiovascular mechanisms of action are poorly understood. Proposed mechanisms range broadly and include enhanced ketogenesis, where the mild ketosis associated with SGLT2i use is presumed to be beneficial.

Heart Failure 72

Heart Failure 72

HCPLive

DECEMBER 16, 2024

Needle-free treatments, such as Neffy and FluMist, offer promising alternatives for children and adults with needle phobia, ensuring access to critical care.

Critical Care 78

Critical Care 78

Medical Xpress - Cardiology

DECEMBER 20, 2024

UC Davis Director of Pediatric Electrophysiology Dan Cortez has set another world record: He is the first to implant a dual chamber leadless pacemaker in a child. His case report was published this week in the journal Pacing and Clinical Electrophysiology.

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Pacemaker Electrophysiology Pediatrics 87

Dr. Smith's ECG Blog

DECEMBER 16, 2024

Which patient needs a CT Scan? Case 1: 20-something woman with chest pain Case 2: 50-something man with chest pain Case 1 A 20-something yo woman presented in the middle of the night with severe crushing chest pain. It had begun 4 hours before arrival and was initially dull, but became severe and "unbearable" 2 hours prior to arrival. She was a walk-in at triage.

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Chest Pain Aortic STEMI Ultrasound 65

The New England Journal of Medicine

DECEMBER 18, 2024

A 63-year-old man with a history of CABG presented with a 2-month history of angina during exertion of the left arm. Angiography revealed retrograde flow in the left internal thoracic artery graft (shown in a video).

Angina 68

Angina 68

Science Daily - Heart Disease

DECEMBER 20, 2024

Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

Artificial Heart 66

Artificial Heart Heart Failure 66

HCPLive

DECEMBER 18, 2024

Findings suggest an association between food allergies and atopic dermatitis control and persistence.

Pediatrics 75

Pediatrics 75

Medical Xpress - Cardiology

DECEMBER 19, 2024

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterolhigh-density lipoproteins (HDL)may be associated with an increased prevalence of cardiovascular disease.

Cholesterol 69

Cholesterol Cardiovascular Disease Research 69

AMS Cardiology

DECEMBER 16, 2024

The magic of the holidays often comes with hidden challenges for our hearts. Rich foods, packed calendars, and holiday pressures can derail even our best health intentions. Yet maintaining heart health doesn’t mean sacrificing the festivities. Simple, mindful choices during the holiday season can protect your cardiovascular health and lay the foundation for a lively year ahead.

Blood Pressure 52

Blood Pressure Risk Factors Diet Cholesterol 52

Dr. Smith's ECG Blog

DECEMBER 20, 2024

Written by Willy Frick with edits by Ken Grauer An older man with a history of non-ischemic HFrEF s/p CRT and mild coronary artery disease presented with chest pain. He said he had had three episodes of chest pain that day while urinating. The following ECG was obtained in the emergency department during active chest pain. ECG 1 What do you think? There is a lot going on in this ECG.

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Chest Pain Tachycardia Pacemaker Defibrillator 57

Science Daily - Heart Disease

DECEMBER 18, 2024

Researchers studied oxygen treatment as a potential therapy to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes and found no significant improvement in function in patients with type 2 diabetes.

Diabetes 65

Diabetes Blood Pressure Research 65

HCPLive

DECEMBER 16, 2024

Laurence Sperling, MD shares insights into a multi-disciplinary approach to the management of obesity from the perspective of a cardiologist.

Obesity 64

Obesity 64

Medical Xpress - Cardiology

DECEMBER 16, 2024

Researchers at 37 sites in South Korea have found patients taking clopidogrel after percutaneous coronary intervention (PCI) experienced lower rates of both thrombotic and bleeding events than those taking aspirin. Clopidogrel's benefits remained consistent regardless of high bleeding risk (HBR) or complex PCI.

Research 65

Research 65

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

Despite improvements in clinical outcomes of acute myocardial infarction (AMI), mortality rates remain high, indicating the need for further understanding of the pathogenesis and developing more effective cardiac protection strategies. Extracellular vesicles (EVs) carry proteins and noncoding RNAs (ncRNAs) derived from different cardiac cell populations, mainly including cardiomyocytes, endothelial cells, endothelial progenitor cells, cardiac progenitor cells, cardiosphere-derived cells, immune

Myocardial Infarction 52

Myocardial Infarction Physiology Biomarkers Innovation 52

Cardiovascular Diabetology

DECEMBER 17, 2024

Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus and causes vision impairment and blindness. The presence of major risk factors for DR, such as high levels of HbA1c, does no.

Diabetes 59

Diabetes Biomarkers Risk Factors Research 59

Science Daily - Heart Disease

DECEMBER 19, 2024

Researchers have discovered that certain components of so-called 'good' cholesterol -- high-density lipoproteins (HDL) -- may be associated with an increased prevalence of cardiovascular disease.

Cholesterol 63

Cholesterol Cardiovascular Disease Research 63

HCPLive

DECEMBER 20, 2024

The FDA's decision not to approve sotagliflozin as an adjunct in T1D and CKD comes less than 2 months after a negative advisory committee meeting for the application.

Diabetes 59

Diabetes 59

Medical Xpress - Cardiology

DECEMBER 19, 2024

Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association.

Atrial Fibrillation 65

Atrial Fibrillation Research AFIB 65

Nature Reviews - Cardiology

DECEMBER 15, 2024

Nature Reviews Cardiology, Published online: 16 December 2024; doi:10.1038/s41569-024-01112-z Macrophagefibroblast interactions have a central role in cardiac fibrosis. In response to left ventricular pressure overload, CCR2+ cardiac macrophages acquire a fibrogenic phenotype, secreting IL-1 and promoting the activation of a FAP+ POSTN+ fibroblast subpopulation through the transcription factor MEOX1.

Heart Failure 59

Heart Failure 59

Med Page Today

DECEMBER 16, 2024

(MedPage Today) -- NEW ORLEANS -- Patients at a community health center who had type 2 diabetes and a high risk of atherosclerotic cardiovascular disease (ASCVD) were under-prescribed guideline-recommended treatment with sodium-glucose cotransporter.

Diabetes 59

Diabetes Cardiovascular Disease 59

Science Daily - Heart Disease

DECEMBER 16, 2024

The lateral habenula is a brain region associated with behavioral changes and autonomic responses during psychological stress. Researchers at the University of Tsukuba have identified the involvement of the dopaminergic system in the cardiovascular responses triggered by neuronal excitation in the lateral habenula. They further determined that the ventral tegmental area of the midbrain, which is the origin of dopamine neurons, plays a mediating role in this response.

Research 61

Research 61

HCPLive

DECEMBER 20, 2024

Tirzepatide's approval marks the first and only prescription medicine available for adults with moderate-to-severe obstructive sleep apnea and obesity.

Obesity 59

Obesity 59

Medical Xpress - Cardiology

DECEMBER 17, 2024

Drinking a small or moderate amount of wine may lower the risk of serious cardiovascular disease in people at a higher risk who are following a Mediterranean diet, according to research published in the European Heart Journal.

Cardiovascular Disease 60

Cardiovascular Disease Diet Research 60

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

Coronary artery disease (CAD)cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteriesis responsible for disabilities of millions of people worldwide and remains the most common single cause of death. Inflammation is the primary pathological mechanism underlying CAD, since is involved in atherosclerotic plaque formation.

Coronary Artery Disease 59

Coronary Artery Disease Atherosclerosis Plaque 59

Dr. Paddy Barrett

DECEMBER 20, 2024

As a cardiologist, I am frequently asked about supplements and heart health. In general, I am not a fan. Personally, I take two supplements. Whey protein for hitting my daily protein targets. Creatine for improving exercise performance and muscle mass. Neither of these supplements is for improving ‘heart health’ During the winter months, I will occasionally take vitamin D if my levels are low, but generally, if I get enough time outside, even during the winter months, I do not need t

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Cardiometabolic Health Congress

DECEMBER 17, 2024

Cardiovascular and renal health are undeniably linkedwhen one system is compromised, the other is often at risk. For healthcare providers, adopting an integrated, patient-centered approach is important for better outcomes. Here are our five top tips to help you stay aligned with the latest guidelines and improve cardiorenal care. 1. Embrace a Multidisciplinary Perspective Cardiorenal health isnt just a focus area for cardiologists and nephrologistsit affects a wide range of specialties, includi

Kidney Disease 52

Kidney Disease CME Research Education 52

HCPLive

DECEMBER 20, 2024

These data resulted from an investigation of the effect of varying image qualities on the diagnostic abilities of a convolutional neural network (CNN) model and clinicians.

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Medical Xpress - Cardiology

DECEMBER 16, 2024

For years, researchers and clinicians have been trying to find a way to rapidly deliver oxygen to patients when traditional means of oxygenation are difficult or ineffective during critical moments of cardiac or respiratory arrest.

Research 56

Research 56

Science Daily - Stroke

DECEMBER 17, 2024

Researchers have revealed how an overlooked type of indirect brain damage contributes to ongoing disability after a stroke. The paper shows how the thalamus -- a sort of central networking hub that regulates functions such as language, memory, attention and movement -- is affected months or years after a person has experienced a stroke, even though it was not directly damaged itself.

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Stroke Strokes Research 55