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IntroductionThe definition of acute kidney dysfunction in patients with acute decompensated heart failure (ADHF) remains unclear. This study aimed to compare two sets of criteria for acute kidney injury (AKI), namely, the kidney disease: improving global outcomes (KDIGO) and worsening renal function (WRF) classification, in hospitalized patients with ADHF.MethodsWe utilized a multi-institutional database with 17,684 cases of hospitalizations for HF.
Here is a rhythm strip from a 3-lead Holter ECG. It comes from a 56-year-old man with arterial hypertension and no other previous cardiac diseases. Recently, the patient has noticed that pulse irregularities occur during blood pressure measurement (which he performs himself at home). On the ECG, first a sinus beat, then a PVC, then an AIVR occurs, which is interrupted by another PVC, then sinus rhythm again.
Circulation, Ahead of Print. Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements. Although people are living longer lives, there may be an adverse impact on quality of life, necessitating a greater need for palliative care services and support. Palliative care for adults with advanced cardiovascular disease has the potential to significantly improve quality of life for individuals living with cardiovascular disease and their
Building stronger evidence for AIs place in cardiology, this week brought several examples of how AI can improve ECG use cases and automate Echo for new disease detection methods. Starting with AI improving ECG for coronary revascularization , a deep learning ECG model outperformed both clinician-led ECG and troponin T testing in predicting which ED patients needed coronary revascularization.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
World Liver Day 2025 | A Global Call to Action for Liver Health through Nutrition A global coalition of leading health organizations unites to mark World Liver Day on Saturday, April 19, emphasizing the pivotal role of nutrition in supporting liver function and preventing disease. With the theme Food is Medicine, the campaign urges the global community to take action through sustainable lifestyle changes.
BackgroundBased on clinical observations and expert recommendations, Baduanjin exercise has demonstrated a positive impact on maintaining and enhancing cardiovascular function. Despite clinical observations of Baduanjin's cardiovascular benefits, systematic evidence for older adults remains limited. Moreover, the effects of Baduanjin exercise on functional capacity in older adults with cardiovascular diseases have not been adequately investigated.
In this ECG Cases blog Dr. Jesse McLaren guides us through 6 illustrative cases delving into overall impression in identifying occlusion MI. He discusses how using multiple OMI findings such as acute Q wave, subtle STE, reciprocal STD, hyperacute T waves, and reciprocal TWI to contribute to your overall impression, can double the sensitivity of STEMI criteria for acute coronary occlusion.
In this ECG Cases blog Dr. Jesse McLaren guides us through 6 illustrative cases delving into overall impression in identifying occlusion MI. He discusses how using multiple OMI findings such as acute Q wave, subtle STE, reciprocal STD, hyperacute T waves, and reciprocal TWI to contribute to your overall impression, can double the sensitivity of STEMI criteria for acute coronary occlusion.
CPT code 93296 is currently reimbursed based on 28 minutes of labor, yet delivering this service takes 84 minutes. Cardiac remote monitoring plays a vital role in proactive care, helping patients avoid complications and reduce hospital visits.1 As care standards evolve, aligning reimbursement with todays clinical reality is essential to uphold guideline-directed remote monitoring.
(MedPage Today) -- Hearing loss may play a bigger role in dementia than previously thought, data from a U.S. cohort study suggested. In a sample of nearly 3,000 older adults, up to 32% (95% CI 11.0%-46.5%) of incident dementia over 8 years could.
Research Highlights: Among adults ages 18-49 (median age of 41 years) who were born with a hole in the upper chambers of their heart known as patent foramen ovale (PFO), strokes of unknown cause were more strongly associated with nontraditional risk.
ObjectiveThe aim of this study was to investigate the impact of preprocedural anticoagulation on the incidence of silent cerebral embolisms (SCEs) assessed by magnetic resonance imaging (MRI) after catheter ablation of atrial fibrillation (AF) in patients with low thromboembolic risk.Methods and resultsA total of 141 patients with AF who were identified with low thromboembolic risk based on CHA2DS2-VASc score (0 or 1 for males and 1 or 2 for females) were enrolled in this study.
Dupilumab's approval marks the first new, targeted therapy for CSU in more than a decade and is the 7th indication for a disease with underlying type 2 inflammation.
Some people get heart disease early in life. But pretty much everyone gets heart disease at some point. We know that heart disease likely begins in childhood. Multiple studies have shown plaque build up in people from their teenage years onwards with significant amounts present by mid 20’s. I presume most of you who are reading this are well past your twenties.
(MedPage Today) -- Welcome to Culture Clinic, MedPage Today's collaboration with Northwell Health to offer a healthcare professional's take on the latest viral medical topics. In an aisle where sports drinks like Gatorade once reigned supreme.
Stroke, Ahead of Print. BACKGROUND:Branch atherosclerosis disease (BAD) is prone to early neurological deterioration (END). The purpose of this study was to assess the efficacy and safety of argatroban plus dual antiplatelet therapy (DAPT) for preventing END in high-risk branch atherosclerosis disease patients.METHODS:This multicenter, open-label, blinded end point, randomized controlled trial including branch atherosclerosis disease patients with mild stroke (National Institutes of Health Strok
Chronic allograft vasculopathy (CAV) is a major cause of late graft failure in heart transplant recipients, characterized by progressive intimal thickening and diffuse narrowing of the coronary arteries. Unlike atherosclerosis, CAV exhibits a distinct cellular composition and lesion distribution, yet its pathogenesis remains incompletely understood.
Journal of the American Heart Association, Ahead of Print. BackgroundNonvitamin K oral anticoagulants prevent stroke and systemic embolism in patients with nonvalvular atrial fibrillation. However, potential drug interactions with concomitant medications may compromise their efficacy and escalate the risk of adverse effects.Methods and ResultsWe conducted a territorywide retrospective cohort study in Hong Kong, focusing on nonvalvular atrial fibrillation prescribed nonvitamin K oral anticoagulan
Atherosclerosis is, by definition, the abnormal retention of a cholesterol particle in the artery wall. Get Access The more particles you throw at your artery wall over a lifetime, the greater the chance one of those particles will be retained and form plaque. That is why addressing high cholesterol early in life is key. The Cholesterol Code explains: WHY people get high cholesterol.
(MedPage Today) -- Reducing hypertension dropped dementia risk by 15% in the open-label China Rural Hypertension Control phase III (CRHC-3) trial of nearly 34,000 people. At 48 months, all-cause dementia among people with high blood pressure was.
Greenspan offers tips in treating seasonal allergies in patients with pulmonary conditions, such as long-COVID, and provides his 2025 spring allergy prediction.
BackgroundThe aim of the present study was to explore the value of coronary artery calcium score (CACS) using non-gated, non-contrast chest computed tomography (NCCT) to predict coronary artery disease (CAD) in airline pilots.MethodsPilots with coronary calcification found on NCCT were consecutively enrolled into this study. All received a coronary computed tomography angiography (CCTA) examination.
tim.hodson Mon, 04/21/2025 - 11:18 April 21, 2025 Stereotaxis, a provider of surgical robotics for minimally invasive endovascular intervention, will host a live demonstration of the GenesisX Robotic System at this years Heart Rhythm Symposium (HRS), taking place April 24-27 in San Diego, CA. This marks the first live, public demonstration of GenesisX, offering a glimpse into the robots clinical capabilities and weekend installation.
“I have high cholesterol, and I don’t know what to do about it.” This is one of the most common scenarios I encounter as a cardiologist focused on preventing heart disease. Unfortunately, many people do not understand cholesterol, and because of this, they wait too long to address the underlying problem. There is a very structured solution to this issue.
Research Highlights A small study found that fatty buildup in the blood vessels of the neck (carotid arteries) may contain 50 times or more micronanoplastics minuscule bits of plastic compared to arteries free of plaque buildup. Plaque, the fatty.
This week marked the final week of my 12-week marathon training block, which I’m referring to as the “Road to Boston.” IT’S RACE WEEK. I want to thank you for following this journey through to the end. It still blows my mind that tens of thousands of people (some strangers, some friends) come here each week to read about how I exercised.
IntroductionCoronary heart disease (CHD) is a leading cause of cardiovascular mortality, with air pollution serving as a significant risk factor. Henan Province, characterized by both a high incidence of CHD and severe air pollution, faces substantial health and economic challenges. However, limited research has explored the relationship between air pollution and CHD in this region.MethodsThis study employs a case-crossover design combined with a distributed lag non-linear model (DLNM) to examin
(MedPage Today) -- The Supreme Court will hear oral arguments Monday in a case that could affect what kind of preventive care is covered at no charge under Americans' health insurance plans. The case, known as Kennedy v. Braidwood, involves Christian.
Stroke, Ahead of Print. BACKGROUND:Stroke often results in significant impairments across various domains, including movement, language, cognition, and mood. Neurostimulants have been proposed as potential therapeutic interventions to enhance recovery in these areas.METHODS:This narrative literature review examines clinical trials investigating the efficacy of neurostimulants in poststroke recovery.
Panelists discuss how differentiating between wild-type transthyretin amyloid cardiomyopathy (wATTR-CM) and hereditary transthyretin amyloid cardiomyopathy (hATTR-CM) is essential for accurate diagnosis, tailored treatment strategies, and better management of patient outcomes, given their distinct pathophysiologies, disease progression, and treatment options.
This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy. Unfavourable outcomes were observed following the minimization or withdrawal of reninangiotensin system inhibitors (RASi), mineralocorticoid receptor antagonists (MRA), or the c
BackgroundAtrial fibrillation (AF) is a common arrhythmia associated with an increased risk of stroke, heart failure, and mortality. Immune infiltration plays a crucial role in AF pathogenesis, yet its mechanisms remain unclear. Lactylation, a novel post-translational modification, has been implicated in immune regulation, but its association with AF remains unexplored.
(MedPage Today) -- After the Senate voted to confirm Robert F. Kennedy Jr. as Health and Human Services (HHS) secretary, supporters of his "Make America Healthy Again" (MAHA) movement cheered at having a champion in the federal government. Now.
Stroke, Ahead of Print. BACKGROUND:The international trial AVERT (A Very Early Rehabilitation Trial) found that very early mobilization (VEM; commenced <24 hours after stroke) negatively affected functional outcome (modified Rankin Scale [mRS]). The drivers of this effect remain unclear. One plausible mechanism is that high-dose upright activity worsens cerebral perfusion in patients with cerebral large vessel occlusion (LVO).
This interview in the latest issue of The Respiratory Report features Divay Chandra, MD, MSc, discussing lithium's potential enhancement of alveolar repair after injury.
If you frequently experience pain in the back of your legs when walking, it could be a sign of Peripheral Artery Disease (PAD). PAD (Peripheral Artery Disease) is a common circulatory condition affecting more than 10 million Americans. PAD causes a narrowing of the peripheral arteries due to fatty plaque buildup (or atherosclerosis) which restricts blood flow to the extremities.
BackgroundGualou Xiebai Banxia Decoction (GXBD), a traditional Chinese medicine, is used to treat myocardial ischemia (MI). However, the molecular mechanisms underlying its effects remain unclear. This study integrated network pharmacology and experimental validation to investigate the efficacy and potential mechanisms of GXBD in MI treatment.MethodsNetwork pharmacology was used to predict the mechanism of action of GXBD in MI.
(MedPage Today) -- Medicaid plans often put up barriers around newer classes of diabetes medications that offer cardioprotection, according to a national study of formulary policies as of March 2024. Mainly driven by restrictive formulary policies.
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