Trending Articles

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New Study to Examine Hypercortisolism in Resistant Hypertension

DAIC

tim.hodson Tue, 03/11/2025 - 11:19 Mar. 10, 2025-- Corcept Therapeutics Inc., a commercial-stage company engaged in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic and neurologic disorders by modulating the effects of the hormone cortisol, recently announced the initiation of Momentum, a clinical trial examining the prevalence of endogenous hypercortisolism (Cushings syndrome) in patients with resistant hypertension.

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CABG Better than PCI for T2D Patients

CardiacWire

One of the biggest risk factors for patients who need coronary revascularization is diabetes, and a new study in JAMA suggests CABG could be a better option than FFR-guided PCI when it comes to long term outcomes for these patients. The debate has been heating up over the last few years on PCI vs. CABG for improving heart bloodflow, but few studies have looked at the benefits for patients with T2D.

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Calcium channel inhibition promotes cardiac regeneration, offering hope for heart failure treatment

Medical Xpress - Cardiology

Researchers report a discovery in cardiac regeneration that offers new hope for the treatment of ischemic heart failure. Published in npj Regenerative Medicine, the study reveals a novel approach to promoting cardiomyocyte proliferation. The researchers are from the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and collaborating institutions.

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How Dr. Nicolas Zea’s Passion for Adventure Fuels His Work in the OR

CTVS

As one of our board certified vascular surgeons, Dr. Nicolas Zea performs a variety of complex procedures, and his dedication to patient care and service is exceptional. What you might not know about him is that he is also an avid adventurer, running ultra marathons and traveling far and wide to embark on trail run excursions and mountain climbing expeditions.

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Patent Foramen Ovale Closure in Patients With and Without Nickel Hypersensitivity: A Randomized Trial

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Nickel-containing devices, such as the Amplatzer PFO Occluder and Gore Cardioform Septal Occluder (GSO), are used for transcatheter patent foramen ovale (PFO) closure. However, the impact of nickel hypersensitivity on post-procedural outcomes remains poorly understood. This study aimed to evaluate the risk of adverse events, in patients with nickel hypersensitivity undergoing PFO closure.Methods:Our study was a prospective, do

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Insomnia and lack of sleep linked to high blood pressure in teens

Medical Xpress - Cardiology

Teenagers who do not get the recommended amount of sleep may be at an increased risk for high blood pressure, according to preliminary research presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Scientific Sessions 2025. The meeting is being held in New Orleans, March 69, 2025, and features the latest science on population-based health and wellness and implications for lifestyle.

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Cells 'speed date' to find their neighbors when forming tissues

Science Daily - Heart Disease

In developing hearts, cells shuffle around, bumping into each other to find their place, and the stakes are high: pairing with the wrong cell could mean the difference between a beating heart and one that falters. A study demonstrates how heart cells go about this 'matchmaking' process. The researchers model the intricate movements of these cells and predict how genetic variations could disrupt the heart development process in fruit flies.

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Investigating the impact of multidimensional sleep traits on cardiovascular diseases and the mediating role of depression

Open Heart

Background Observational studies have reported that sleep is associated with the risk of major depressive disorder (MDD) and cardiovascular diseases (CVDs). However, the causal relationships among various sleep traits remain contentious, and whether MDD mediates the impact of specific sleep traits on CVDs is unclear. Methods We performed two-sample Mendelian randomisation analyses to explore whether insomnia, sleep time, daytime napping, daytime sleepiness, chronotype, snoring or obstructive sle

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Retinal vascular fingerprints predict incident stroke: findings from the UK Biobank cohort study

Heart BMJ

Objective To investigate the associations between a comprehensive set of retinal vascular parameters and incident stroke to unveil new associations and explore its predictive power for stroke risk. Methods Retinal vascular parameters were extracted from the UK Biobank fundus images using the Retina-based Microvascular Health Assessment System. We used Cox regression analysis, adjusted for traditional risk factors, to examine the associations, with false discovery rate adjustment for multiple com

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Medtronic Presents New Data, Clinical Milestones at CRT 2025

DAIC

tim.hodson Mon, 03/10/2025 - 11:17 At the Cardiovascular Research Technologies (CRT) 2025 conference in Washington, D.C., Medtronicpresented new data and clinical milestones across its Coronary, Structural Heart and Renal Denervationbusinesses. The conference will showcase key data presentations and advancements across its Coronary, Structural Heart and Renal Denervation businesses in the Medtronic Cardiovascular portfolio.

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Walking, moving more may lower risk of cardiovascular death for women with cancer history

American Heart News - Heart News

Research Highlights: Increased physical activity including taking more daily steps was linked to a lower risk of death from cardiovascular disease among postmenopausal women with a history of cancer. The study found that engaging in one hour per day.

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Optimal antithrombotic therapy after transcatheter aortic valve replacement: a comprehensive review

Frontiers in Cardiovascular Medicine

Transcatheter aortic valve replacement (TAVR) has become a leading treatment for aortic stenosis, but managing thromboembolic and bleeding risks post-procedure remains challenging. This review examines current evidence on antithrombotic therapy after TAVR. Subclinical leaflet thrombosis is observed in 10%20% of patients, though its clinical significance remains uncertain.

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Long-Term Use of NSAIDs Linked to Lower Dementia Risk

Med Page Today

(MedPage Today) -- Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) was tied to a decreased risk of dementia, data from the prospective Rotterdam Study showed. Over an average follow-up of 14.5 years, use of NSAIDs for 24 months.

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Outcomes of tricuspid valve surgery in patients with significant tricuspid regurgitation and low to intermediate risk

Heart BMJ

Background In patients with tricuspid regurgitation (TR), delayed surgical intervention is associated with poor outcomes, particularly in advanced stages. This study aimed to assess whether earlier tricuspid valve (TV) surgery provides a survival benefit in patients with moderate to severe TR who are considered at low to intermediate risk of adverse clinical or surgical outcomes.

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AI Image Analysis App Receives FDA 510(k) Clearance

DAIC

tim.hodson Tue, 03/11/2025 - 10:25 March 11, 2025 Caristo Diagnosticshas received U.S. Food and Drug Administration (FDA) 510(k) clearance of its CaRi-Plaquetechnology, an AI-assisted image analysis application to aid the diagnosis of coronary artery disease (CAD). The CaRi-Plaque technology supports non-invasive analysis of coronary anatomy and pathology from routine coronary computed tomography angiography (CCTA) scans to determine the presence, extent and severity of coronary plaques and lum

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Young Woman Shares Lessons Learned After Mitral Valve Repair

CTVS

For 27-year-old Rachael Boyle, heart health was a familiar topic. Her younger brother had experienced heart problems as a teenager, but she had always been healthy. That all changed when she fell ill in April 2024. As Rachael wrapped up her spring semester at the University of Texas, she started experiencing persistent fevers and headaches.

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Immunosuppressant adherence after heart transplantation: a review on detection, prevention, and intervention strategies in a multidisciplinary

Frontiers in Cardiovascular Medicine

Heart transplantation is an effective treatment for end-stage heart disease, and postoperative patients' medication adherence is crucial for transplantation outcomes and long-term survival. By reviewing a large amount of related literature, this review summarizes the current status, evaluation methods, influencing factors, and intervention strategies of medication adherence after heart transplantation, emphasizes the important role of multidisciplinary teams in improving medication adherence, an

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ACC Practice Made Perfect: Women in Leadership Positions: Tips and Barriers

American College of Cardiology

In this episode, Dr. Koh hosts Drs. Sharmila Dorbala and Victoria Delgado who share their personal experiences in becoming a woman leader in cardiology. Drs. Dorbala and Delgado elaborate on how the landscape of women leadership in cardiology has changed, their paths towards becoming successful leaders in their field, and tips for women who wish to ascend towards leadership positions.

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Reassessing the role of tricuspid valve surgery in the modern era

Heart BMJ

The tricuspid valve (TV), historically deemed the ’forgotten valve’, is undergoing a renaissance as mounting evidence highlights its critical role in cardiovascular outcomes. The article by Gwak et al provides a pivotal contribution to this field, illustrating that early surgical intervention for tricuspid regurgitation (TR) in patients with low to intermediate risk yields significant survival benefits. 1 This editorial expands on these findings, weaving them into the broader fabric

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Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the European Association of Preventive Cardiology of the European Society of Cardiology

European Journal of Heart Failure

For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and effort intolerance than both the general population and people with other chronic conditions, since they present a range of physical and psychological symptoms, including shortness of breath, chest discomfort, fatigue, fluid congestion, trouble with sleeping, and

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Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

Science Daily - Heart Disease

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

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Autophagy fine-tuning by angiotensin-(1-9) in cultured rat cardiomyocytes

Frontiers in Cardiovascular Medicine

BackgroundThe renin-angiotensin system (RAS) plays a pivotal role in regulating blood volume, systemic vascular resistance, and electrolyte balance, serving as a key component of cardiovascular health. Recent findings highlight the role of angiotensin II (Ang II) in inducing autophagy through angiotensin II receptor type 1 (AT1R). Autophagy, a process of self-degradation and turnover of cellular components, is a homeostatic response that eliminates superfluous materials.

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Study Supports Real Grocery Store Food for Safe, Accessible Sublingual Immunotherapy

HCPLive

Among 162 patients in the study, 99% reported satisfaction of sublingual immunotherapy with real grocery store food.

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Broward Health Adds Pulsed Field Ablation Sytsem to Treat A-fib

DAIC

tim.hodson Wed, 03/12/2025 - 15:36 Broward Health recently announced it is now offering the Farapulse Pulsed Field Ablation System to treat atrial fibrillation (A-Fib). This innovative treatment represents a significant advancement over traditional thermal ablation methods and provides a more effective solution for patients. Farapulse Field Ablation System from Boston Scientific Pulsed Field Ablation is a game-changer in cardiovascular care," said Jose Baez, M.D., Broward Healths chief of cardio

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Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta‐analysis

European Journal of Heart Failure

Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis. Clonal haematopoiesis and heart failure: a meta-analysis. CH, clonal haematopoiesis; CI, confidence interval; HF, heart failure. Abstract Aims Clonal haematopoiesis (CH) is recognized as a significant risk factor for various non-haematologic conditions, including cardiovascular diseases.

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Better Diet, Better Brains

Med Page Today

(MedPage Today) -- Healthier diet and lower waist-to-hip ratio throughout midlife were associated with better brain and cognitive health in older age, longitudinal data from the Whitehall II cohort study in England showed. A better midlife diet.

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Predictors for long-term outcome of pulmonary valve perforation and balloon valvuloplasty in neonates with critical pulmonary valve stenosis or pulmonary valve atresia with intact ventricular septum

Frontiers in Cardiovascular Medicine

IntroductionPercutaneous balloon valvuloplasty is the treatment of choice for critical pulmonary valve stenosis (CPS) and pulmonary valve atresia with intact ventricular septum (PA/IVS) if the ventricle has a suitable size. This study aimed to evaluate the long-term outcomes and predictors for surgical intervention and pulmonary valve replacement in patients with CPS or with PA/IVS after PBV, considering different morphological and hemodynamic parameters.MethodsNeonates with PA/IVS or CPS who we

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Investigating Pollution Sources and Asthma Morbidity in Communities of Color, with Sarah Chambliss, PhD

HCPLive

Chambliss and colleagues found a 1% increase in asthma-related emergency department visits per unit of distance to semiconductor fabrication plants.

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Food insecurity today, heart disease tomorrow?

Science Daily - Heart Disease

Struggling to afford food today could mean heart problems tomorrow. Young adults experiencing food insecurity have a 41% greater risk of developing heart disease in midlife, even after accounting for demographic and socioeconomic factors, according to a new study. Food insecurity -- struggling to get enough nutritious food to stay healthy -- affects one in eight households in the U.S. each year.

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Comprehensive Multiomic Analysis Reveals Metabolic Reprogramming Underlying Human Fontan‐Associated Liver Disease

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundThe Fontan operation is the current standard of care for singleventricle congenital heart disease. Almost all patients with Fontan operation develop liver fibrosis at a young age, known as Fontanassociated liver disease (FALD). The pathogenesis and mechanisms underlying FALD remain little understood, and there are no effective therapies.

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Study the US finds growing heart disease gap linked to wealth, education

Medical Xpress - Cardiology

A study published in The Lancet Regional HealthAmericas highlights a growing divide in cardiovascular health in the U.S., showing that wealth and education play a significant role in heart disease risk.

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A universal model for predicting coronary artery lesions in subgroups of kawasaki disease in China: based on cluster analysis

Frontiers in Cardiovascular Medicine

ObjectiveCoronary artery lesions (CAL) represent the most severe complication of Kawasaki disease (KD). Currently, there is no standardized method for predicting CAL in KD, and the predictive effectiveness varies among different KD patients. Therefore, our study aims to establish distinct predictive models for CAL complications based on the characteristics of different clusters.MethodsWe employed principal component clustering analysis to categorize 1,795 KD patients into different clustered sub

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Heart Valve Disease Forum 2025

Society of Thoracic Surgeons - Congenital

Event Heart Valve Disease Forum 2025 kchalko Thu, 03/13/2025 - 14:32 Event dates Sep 1213, 2025 Location Seoul, Korea STS is pleased to co-present the Heart Valve Disease Forum (HVDF) with the Korean Society for Thoracic and Cardiovascular Surgery, offering the latest knowledge regarding the basics, diagnosis, treatment, and future of valvular heart disease.

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Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

Science Daily - Heart Disease

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

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Transcatheter Edge‐to‐Edge Repair for Severe Mitral Regurgitation in Patients With Cardiogenic Shock: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundPatients with severe mitral regurgitation and cardiogenic shock demonstrate a poor prognosis. Mitral transcatheter edgetoedge repair could alter patient management.Methods and ResultsWe systematically reviewed PubMed/Medline, Scopus, and Cochrane Library until January 2023, including studies assessing transcatheter edgetoedge repair in patients with severe mitral regurgitation and cardiogenic shock.

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Thrombotic Thrombocytopenic Purpura: A Missed Cause in Stroke Prevention Guidelines

Stroke Journal

Stroke, Ahead of Print. The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming to reduce the growing impact of cerebrovascular disease. These guidelines emphasize modifiable risk factors and population-specific considerations, covering a range of cardiovascular conditions, including hypertension, diabetes, atherosclerotic disease, and genetic predisposit

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Remnant cholesterol, lipid ratios, and the severity of coronary artery lesions: a retrospective cohort study in patients with coronary heart disease

Frontiers in Cardiovascular Medicine

BackgroundEmerging genetic and observational evidence indicates that remnant cholesterol (RC) is a significant residual risk factor for cardiovascular diseases. However, there is a relative paucity of evidence exploring the correlation among RC, lipid ratios, and atherosclerotic lesion severity. This study aimed to investigate the predictive value of RC and lipid ratios alone or in combination for the severity of coronary artery stenosis in patients with coronary heart disease (CHD).MethodsThe G