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Factor XI as a Drug Target for the Prevention and Treatment of Thrombosis

Journal of Cardiovascular Pharmacology

The optimal anticoagulation therapeutic intervention balances preventing or treating thrombosis, depending on the clinical scenario, and bleeding. A novel drug target, factor eleven (FXI), may theoretically represent a way to prevent thrombosis in the clotting cascade, without increasing the risk of bleeding. All rights reserved.

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Allegheny General Hospital First in Western PA to Participate in Clinical Trial Using Artificial Intelligence to Detect Deep Vein Thrombosis in Cardiac Patients

HCPLive

The AI-powered trial was officially initiated in January 2025.

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Imperative Care Expands Precision Thrombectomy Portfolio

DAIC

tim.hodson Mon, 03/24/2025 - 15:48 March 24, 2025 Imperative Care, Inc. The catheter is designed to elevate care for patients with venous thrombosis, a serious condition caused by a blood clot forming in the veins of the legs or abdomen that can have a life-threatening impact if left untreated. recently announced U.S.

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Abstract TP268: Xylitol, Xylose, and MicroRNAs Associated with Thrombosis and the Clotting Cascade in a Multi-Omics Cross-Sectional Study of Adults at Risk for Type 2 Diabetes and Stroke

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack. The mean BMI was 35.2 kg/m2, HbA1c was 5.9% 0.4,

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Pathology of Self-Expanding Transcatheter Aortic Bioprostheses and Hypoattenuated Leaflet Thickening

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Volume 18, Issue 2 , Page e014523, February 1, 2025. BACKGROUND:Hypoattenuated leaflet thickening (HALT) is believed to reflect leaflet thrombosis; however, no systematic histological examination of HALT has ever been performed.

Aortic 75
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Aspirin Plus Rivaroxaban Versus Rivaroxaban Alone for the Prevention of Venous Stent Thrombosis Among Patients With Post-Thrombotic Syndrome: The Multicenter, Multinational, Randomized, Open-Label ARIVA Trial

Circulation

Circulation, Volume 151, Issue 12 , Page 835-846, March 25, 2025. The risk of stent thrombosis is particularly increased during the first 6 months after intervention. Key exclusion criteria included <18 or >75 years of age, contraindications to anticoagulant use, or acute venous thrombosis <3 months.

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Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

DAIC

tim.hodson Mon, 03/31/2025 - 16:38 March 29, 2025 Anthos Therapeutics, Inc., 2025 If you enjoy this content, please share it with a colleague presented two new analyses from itsAZALEA-TIMI 71 study at the American College of Cardiology Annual Scientific Session (ACC.25) 2021 4 Hsu et al. J Am Coll Cardiol. J Thromb Haemost.