Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP299-ATP299, February 1, 2025. Introduction:Prior studies have demonstrated social determinants of health (SDH) are associated with reduced rates of intravenous thrombolysis (IVT) for acute ischemic stroke (AIS), including in disadvantaged populations.

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Thrombolysis Stroke Strokes Research 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP3-ADP3, February 1, 2025. Background:Current guidelines for ischemic stroke recommend initiating intravenous thrombolytic therapy within 4.5 hours after stroke onset or the last known well time. These modalities can identify viable brain tissue beyond the 4.5-hour

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP9-AWP9, February 1, 2025. Background:Acute ischemic stroke can result from extracranial arterial dissection. The effectiveness and safety of intravenous thrombolysis (IVT) for acute ischemic stroke in these cases, particularly those involving large vessel occlusions, are debated.

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Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP20-ATP20, February 1, 2025. The primary outcome was 3-month functional outcome by modified Rankin scale (mRS). Patients with elevated traditional risk factors at admission may benefit more from thrombolytic therapy compared to those with high inflammatory response indicators.

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Thrombolysis Stroke Strokes Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP1-ADP1, February 1, 2025. Whether intravenous thrombolysis (IVT) is safe and effective for acute ischemic stroke (AIS) patients with CAA is largely unknown.Methods:This was an explorative analysis of a nationwide database of hospitalizations in the United States.

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Thrombolysis Stroke Strokes Cerebrovascular Disease 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP1-AWP1, February 1, 2025. Background and aims:Central retinal artery occlusion (CRAO) is a rare but significantly underestimated form of ischemic stroke. One of the considered and currently increasingly preferred options is intravenous thrombolysis. years, 46.9%

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Thrombolysis Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP14-AWP14, February 1, 2025. Introduction:The use of IV thrombolysis (IVT) in acute ischemic stroke patients presenting with an NIHSS of 5 has failed to demonstrate benefit, particularly when the symptoms are considered non-disabling. Kappa = 0.26 [95% CI 0.23 0.29]) (Table 1).

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Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP253-AWP253, February 1, 2025. Background and Aims:Endovascular treatment (EVT) alone has been confirmed to be non-inferior to intravenous thrombolysis (IVT) followed with EVT in acute ischemic stroke (AIS) due to large-vessel occlusion of the anterior circulation.

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Thrombolysis Stroke Strokes Stents 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP19-AWP19, February 1, 2025. We aim to assess the ability of ChatGPT to guide the decision for intravenous thrombolysis (IVT) in patients with acute ischemic strokes (AIS).Methods:The Introduction:Artificial intelligence is emerging as an adjunct promising tool in medicine.

Thrombolysis 40

Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP6-AWP6, February 1, 2025. Background and Purpose:Whether imaging markers of cerebral small vessel disease on computed tomography (CT-CSVD) relates to early clinical outcomes after intravenous thrombolysis for acute ischemic stroke remains not well understood. 1.95, p = 0.019).Conclusion:This

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Thrombolysis Outcomes Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP8-AWP8, February 1, 2025. Introduction:Current guidelines recommend 24-hours of high-intensity monitoring (HIM) for acute ischemic stroke patients post-intravenous thrombolysis (IVT) due to risk of bleeding complications including symptomatic intracranial hemorrhage (sICH).

Thrombolysis 40

Thrombolysis ICU Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP115-ATP115, February 1, 2025. Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT).

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Thrombolysis Stroke Strokes Quality of Life 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP256-AWP256, February 1, 2025. Introduction:In acute stroke patients who receive revascularization with endovascular thrombectomy (EVT) alone vs intravenous thrombolysis (IVT) followed by EVT, combination treatment has shown improved outcomes measured by the modified Rankin Scale (mRS).

Thrombolysis 40

Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP11-ATP11, February 1, 2025. Introduction:Current guidelines suggest using intravenous thrombolysis (IVT) for patients experiencing acute ischemic stroke within 4.5 IVT patients had similar stroke severity at baseline (median NIHSS 4.5 (2.0-6.0) hours of symptom onset.

Thrombolysis 40

Thrombolysis Stroke Strokes Education 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP4-ADP4, February 1, 2025. Introduction:Intravenous thrombolysis with alteplase (tPA) or tenecteplase (TNK) is a first-line treatment for acute ischemic stroke. The most serious risk associated with IV thrombolytics is symptomatic intracranial hemorrhage (sICH).

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Thrombolysis Hemorrhage Document ICU 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP24-ATP24, February 1, 2025. Introduction:Mobile Stroke Units (MSUs) are proven to shorten the time between stroke recognition and thrombolysis resulting to better patient outcomes and are deemed safe and cost-effective.

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP19-ATP19, February 1, 2025. Background:Patients with acute ischemic stroke and a large vessel occlusion (LVO) admitted to primary stroke centers (PSC) often require inter-facility transfer for thrombectomy.

Thrombolysis 40

Thrombolysis Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP26-ATMP26, February 1, 2025. Introduction:Telestroke has the potential to revolutionize acute stroke treatment by improving access to optimal stroke care, including time-sensitive care such as thrombolysis. vs 39.0%) and less at comprehensive stroke centers (13.3%

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Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP108-AWP108, February 1, 2025. Background:Emergency medical services (EMS) routing of stroke patients is challenging in rural settings. This analysis will be repeated once follow-up is completed in 7 months.

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Stroke Strokes Thrombolysis Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP3-AWP3, February 1, 2025. Introduction:Large vessel recanalization (LVR) is a well described phenomenon following intravenous thrombolysis (IVT). LVR patients had lower NIH Stroke Scale (p=0.006) and higher Tan CS (p=0.019). 0.90], p=0.024).

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Thrombolysis Outcomes Circulation Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP84-ATP84, February 1, 2025. Access to acute stroke care varies widely worldwide, with significant gaps in low- and middle-income countries and in rural areas. For instance, CT/radiology support is available 24/7 in over 80% of hospitals, which is crucial during stroke alerts.

Stroke 40

Stroke Strokes Thrombolysis ICU 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP87-ATP87, February 1, 2025. Background:Early prediction of functional outcome after rtPA helps clinicians in prognostic conversations with stroke patients and their families. 12% of the cohort (n=34) had posterior circulation stroke. Of those, 43% (n=119) were male.

Thrombolysis 40

Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP72-AWP72, February 1, 2025. Background:Our system, comprised of 21 Northeast Ohio hospitals includes 3 Stroke Ready, 10 Primary and 1 Comprehensive Stroke Center (CSC). Alteplase remained on formulary for pediatric stroke and other diagnoses.

Stroke 40

Stroke Strokes Thrombolysis Nursing 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A2-A2, February 1, 2025. Background:For patients meeting eligibility criteria, endovascular thrombectomy (EVT) remains the gold standard treatment for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO).

Thrombolysis 40

Thrombolysis Hemorrhage Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP44-ATMP44, February 1, 2025. Introduction:Understanding factors that contribute to missed diagnoses of acute ischemic stroke (AIS) may improve diagnostic accuracy. treatment window for thrombolysis. treatment window for thrombolysis. window (60% vs 40%, p<0.01).

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Stroke Strokes Thrombolysis Education 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP91-AWP91, February 1, 2025. Introduction:Education campaigns have previously successfully informed the public regarding stroke symptoms and the need for urgent evaluation of suspected stroke. received thrombolysis and 53.6%

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Stroke Strokes Thrombolysis Education 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP259-ATP259, February 1, 2025. Background:Endovascular treatment (EVT) is an effective treatment for acute ischemic stroke in anterior large vessel occlusions. In a multivariable regression analysis, intravenous thrombolysis administration (OR 3.27 [95% CI: 1.04-10.33];

Outcomes 40

Outcomes Thrombolysis Stroke Strokes 40

Stroke Journal

DECEMBER 9, 2024

Stroke, Volume 56, Issue 1 , Page 183-189, January 1, 2025. BACKGROUND:Thrombectomy for acute large vessel occlusion is a well-established treatment for stroke prevention. Infarct expansion, defined as a decrease in Alberta Stroke Program Early CT Score, occurred in 23 cases (12/28 TICI 2b and 11/37 TICI 2c/3).

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Thrombolysis Stroke Strokes Hemorrhage 68

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AHUP18-AHUP18, February 1, 2025. Introduction:Research shows that ischemic stroke patients with limited English proficiency (LEP) experience disparities in stroke care, including increased time to treatment with intravenous thrombolysis. poor connection, poor audio quality).

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Stroke Strokes Nursing Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP60-AWMP60, February 1, 2025.

Stroke 40

Stroke Strokes Thrombolysis Document 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP354-AWP354, February 1, 2025. Background:Circulating neuroinflammatory factors change rapidly in acute stroke, but the association with ischemic lesion size and stroke severity is unknown. Twenty-six (57%) MSU patients were confirmed ischemic stroke (AIS). range 0-171) mL.

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Stroke Strokes Circulation Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP53-AWMP53, February 1, 2025. Background:Treatment options and outcomes in stroke also depends on pre-hospital delays. Compared to the patients who reached by non-EMS mode, patients who reached by EMS mode were more likely to receive intravenous thrombolysis (16% vs 44%,).

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Hospital Stroke Strokes Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP83-AWMP83, February 1, 2025. Background:Acute stroke management requires rapid triage and a highly efficient team to work together for prompt diagnosis and acute reperfusion therapy.

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Stroke Strokes Thrombolysis Nursing 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP165-AWP165, February 1, 2025. This is especially critical for wake-up strokes where emergent brain magnetic resonance imaging (eMRI-brain) is included in the evaluation process. It is important to note that stroke onset may have influenced the presence of DWI-FLAIR mismatch.

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Stroke Strokes Thrombolysis Academic 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP140-ATP140, February 1, 2025. Blackground:Due to the narrow therapeutic time window and strict indications, there are still a large number of patients unable to receive thrombolysis and endovascular therapy, resulting in a poor long-term functional prognosis. AUC range:0.65-0.99).Conclusion:We

Biomarkers 40

Biomarkers Stroke Strokes Technology 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP43-ADP43, February 1, 2025. Objective:Most patients with concern for an acute stroke are transported by Emergency Medical Services (EMS) or a Mobile Stroke Unit (MSU) from community hospitals to a Comprehensive Stroke Center (CSC).

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Stroke Strokes Thrombolysis Academic 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP260-AWP260, February 1, 2025. Background:The mechanisms by which intracranial atherosclerosis (ICAS) contributes to large-vessel occlusion strokes (LVOS) remains unclear. Among patients with lower fibrinogen levels (< 3.2g/L),

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Atherosclerosis Stroke Strokes Atrial Fibrillation 40