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tim.hodson Mon, 03/31/2025 - 15:39 March 30, 2025 Medtronic has announced late-breaking data on five-year outcomes from the Evolut Low Risk Trial. Two-Year Outcomes of the Five-Year SMART Trial, presented at CRT 2025. Reardon, M.D., Evolut TAVR vs. 9.3% 1 Herrmann H. If you enjoy this content, please share it with a colleague
tim.hodson Tue, 03/04/2025 - 14:11 Feb. each year, according to the American Heart Association 2025 Heart Disease and Stroke Statistical Update. Learn more about hart valve disease, aortic stenosis and the American Heart Association's educational initatives at heart.org.
Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025. Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management. However, 3 percutaneous angioplasty and stenting randomized trials showed negative or neutral results.
tim.hodson Mon, 03/31/2025 - 10:26 March 31, 2025 AGEPHA Pharma USA, LLC, has released clinical data that provides new information about how low-dose colchicine, 0.5 mg can prevent heart attack and stroke in high-risk patients with established cardiovascular disease. These new data reinforce the use of LODOCO(colchicine, 0.5
Stroke, Volume 56, Issue Suppl_1 , Page ATMP57-ATMP57, February 1, 2025. Introduction:Literature demonstrates that nearly one-third of acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) or severe stenosis arrive at the emergency room with mild symptoms, attributed to favourable collateral status.
Stroke, Volume 56, Issue Suppl_1 , Page AWP16-AWP16, February 1, 2025. Introduction:Currently, no level A evidence exists for the optimal rescue strategy for cases at high risk for re-occlusion following endovascular thrombectomy (EVT) in acute ischemic stroke. female, mean age 63.9). female, mean age 63.9).
Stroke, Volume 56, Issue Suppl_1 , Page ATP215-ATP215, February 1, 2025. Background:Carotid stenosis has been associated with stroke and cognitive impairment. Severity of carotid stenosis was defined using NASCET criteria as <50% (mild), 50-69% (moderate), >70% (high-grade).
tim.hodson Tue, 03/11/2025 - 10:25 March 11, 2025 Caristo Diagnosticshas received U.S. Food and Drug Administration (FDA) 510(k) clearance of its CaRi-Plaquetechnology, an AI-assisted image analysis application to aid the diagnosis of coronary artery disease (CAD).
FAME 2 Purpose FAME 2 sought to evaluate whether FFR-guided PCI plus optimal medical therapy (OMT) was superior to OMT alone in patients with stable CAD and at least one functionally significant stenosis (FFR 0.80). 2025 Mar 28:S0140-6736(25)00505-7. for PCI vs. 6.9% Reference 1.Fearon doi: 10.1016/S0140-6736(25)00505-7.
Stroke, Volume 56, Issue Suppl_1 , Page ATP219-ATP219, February 1, 2025. However, few reports have discussed CNs in the context of carotid artery stenosis. However, few reports have discussed CNs in the context of carotid artery stenosis. of patients with moderate to severe carotid artery stenosis who underwent CEA.
Stroke, Volume 56, Issue Suppl_1 , Page AWP286-AWP286, February 1, 2025. Background:Hemodynamic evaluation is crucial in assessing stroke risk in patients with symptomatic intracranial atherosclerotic stenosis (sICAS). Twenty patients (9.6%) experienced ischemic stroke or TIA during the one-year follow-up.
Stroke, Volume 56, Issue Suppl_1 , Page A39-A39, February 1, 2025. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial. Balloon expandable stent (BES) and self-expanding stent (SES) were used in 54 and 224 patients, respectively.
Stroke, Volume 56, Issue Suppl_1 , Page AWP252-AWP252, February 1, 2025. Baseline angiograms were reviewed to assess the presence or absence of intracranial stenosis lesions (IS+ Vs IS-) different than the target occlusion. Bailout strategies were required more often in the IS+ group (34.6% minutes; p=0.018). Vs 3; p=0.036).Conclusions:Our
Stroke, Volume 56, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2025. Patients with extracranial vertebral artery (V1-2) 70% to 99% stenosis and transient ischemic attack or ischemic stroke within the past 3 months will be recruited (first patient enrollment: Sep 15, 2023).Results:A
Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025. For this study, acute symptomatic was defined as hemispheric ischemic stroke or retinal ischemia ipsilateral to the carotid stenosis, with symptom onset within 24 hours of admission. were asymptomatic and 40.2% acute symptomatic.
Stroke, Volume 56, Issue Suppl_1 , Page ATP293-ATP293, February 1, 2025. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4% vs 2.9%, p < 0.001).
Stroke, Volume 56, Issue Suppl_1 , Page AWP205-AWP205, February 1, 2025. CTAs were reviewed to assess the carotid stenosis and the anatomy of the aortic arch. Additionally, the severity of carotid stenosis in CEA-treated side was higher in patients with bovine arch compared to normal controls (82.5% [76.2-88.7]
Stroke, Volume 56, Issue Suppl_1 , Page AWP347-AWP347, February 1, 2025. Ischemic stroke, a heterogeneous disease with various etiological subtypes and risk factors, places stress on the BBB. To model stenosis, a microactuator was mounted on a 3D printed platform and connected to a capillary tube (~1 mm diameter).
Stroke, Volume 56, Issue Suppl_1 , Page ADP36-ADP36, February 1, 2025. All patients had headache, and funduscopic examination demonstrated papilledema for all patients. All patients had headache, and funduscopic examination demonstrated papilledema for all patients.
Stroke, Volume 56, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2025. We aimed to investigate the association between VAH and atherosclerotic stenosis of subclavian artery (SA), vertebral artery (VA) and basilar artery (BA) based on digital subtraction angiography (DSA).Methods:In VAH and stenosis degree of the artery (i.e.,
Stroke, Volume 56, Issue Suppl_1 , Page A38-A38, February 1, 2025. Background and Purpose:We aimed to investigate the effects of evolocumab, a proprotein convertase subtilisin/kexin type-9 inhibitor for intensive lipid-lowering, on intracranial atherosclerotic stenosis (ICAS).Methods:From 0.11] vs. evolocumab-: 0.02 [0.04-0.07]),
Stroke, Volume 56, Issue Suppl_1 , Page ATP220-ATP220, February 1, 2025. Patients with ICAS having no or only mild stenosis (30%) of the ipsilateral extracranial ICA (C1) were included. The degree of stenosis and distribution pattern of atherosclerotic stenosis for each of 6 segments (C2-7) were analyzed.
Stroke, Volume 56, Issue Suppl_1 , Page ATP128-ATP128, February 1, 2025. Background:Postoperative complication rates of carotid endarterectomy (CEA) and carotid artery stenting (CAS) for carotid artery stenosis are recommended to be maintained below a certain threshold.
Stroke, Volume 56, Issue Suppl_1 , Page ATP274-ATP274, February 1, 2025. Background:Intracranial artery stenosis (ICAS) is a progressive pathological process. 5.2), 60 (6.0%) patients with asymptomatic ICAS had a first-ever ischemic stroke, 63 (6.3%) died, and 7.6% All patients received follow-ups through August 2023.
Stroke, Volume 56, Issue Suppl_1 , Page AWP56-AWP56, February 1, 2025. In this study, we evaluated the relationship between flossing and ICAS, defined as 50% stenosis. These results emphasize the importance of dental flossing in reducing the rates of CSVD and moderately severe ICAS, both known risk factors for ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP49-ATMP49, February 1, 2025. Background and Objective:A stable perfusion pattern may guarantee a good clinical outcome in acute stroke patients. Recanalization status was evaluated through follow-up perfusion or angiography imaging. 95% CI: 2.9 - 26.4, 95% CI: 1.1 - 83.8,
Stroke, Volume 56, Issue Suppl_1 , Page A71-A71, February 1, 2025. Background:The ideal timing of carotid artery stenting (CAS) in symptomatic internal carotid artery (ICA) stenosis is partly determined by the risk of stroke and/or death associated with timing of the procedure. for Days 31-180).
Stroke, Volume 56, Issue Suppl_1 , Page A41-A41, February 1, 2025. This is largely due to the Stenting and Aggressive Medical Management Therapy for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial results which featured a high periprocedural stroke rate.
Stroke, Volume 56, Issue Suppl_1 , Page ATP222-ATP222, February 1, 2025. Background:Symptomatic intracranial atherosclerotic disease carries a high stroke recurrence rate. Accurate prediction of stroke recurrence is critical for improving patient outcomes through timely and targeted interventions.
Stroke, Volume 56, Issue Suppl_1 , Page ATP296-ATP296, February 1, 2025. Introduction:Nonstenotic carotid plaque is found in some patients with otherwise cryptogenic stroke (CS) but also in normal individuals and patients with stroke of known cause (KS).
Stroke, Volume 56, Issue Suppl_1 , Page ATMP58-ATMP58, February 1, 2025. Baseline demographics and National Institutes of Health Stroke Scale (NIHSS) were similar between groups. However, in hyperacute ischemic infarcts, diffusion-weighted imaging (DWI) hyperintense lesions can show varying ADC values. P < 0.0001).
Stroke, Volume 56, Issue Suppl_1 , Page ATP329-ATP329, February 1, 2025. Background/Aim:Up to 20% of people have a hospital encounter in the 30 days before a first ever stroke, suggesting opportunities for better primary prevention. The reasons for these healthcare encounters before stroke have been largely unexplored.
Stroke, Volume 56, Issue Suppl_1 , Page ATP179-ATP179, February 1, 2025. The clinical significance of the HARM sign in transient ischemic attack (TIA) has rarely been studied, unlike that in stroke. The clinical significance of the HARM sign in transient ischemic attack (TIA) has rarely been studied, unlike that in stroke.
Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. Introduction:The middle cerebral artery (MCA) is the most common site for inrtacranial atherosclerotic stenosis. Demographic data, risk factors and the history of ischemic stroke of all patients were recorded. 21.35), p<0.001).Conclusions:Both
Stroke, Volume 56, Issue Suppl_1 , Page AWMP107-AWMP107, February 1, 2025. Background:Early detection of carotid artery (CA) conditions such as atherosclerosis and dissection are important as they represent major preventable causes of stroke. These patients had varying CA conditions (atherosclerosis, dissection, normal, etc.)
Stroke, Volume 56, Issue Suppl_1 , Page ATMP12-ATMP12, February 1, 2025. Aortic stenosis (AS) is an age-related valve disease that is associated with a high rate of MACE.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP10-ATMP10, February 1, 2025. Recently, cilostazol plus other antiplatelet agents combined therapy (CT) has been reported to reduce recurrent stroke, and eicosapentaenoic acid (EPA) has been reported to reduce the risk of cardiovascular events and plaque progression.
Stroke, Volume 56, Issue Suppl_1 , Page ATP288-ATP288, February 1, 2025. Carotid atherosclerosis (CAS) is a critical precursor to atherosclerotic cardiovascular disease and is closely associated with the development and progression of conditions such as stroke and poor prognosis. 2021-KY-1289-001).Results:Among respectively.
Stroke, Volume 56, Issue Suppl_1 , Page ATP248-ATP248, February 1, 2025. Objective:Silent brain infarctions (SBIs), which appear as dot-like lesions on diffusion-weighted imaging (DWI) after endovascular procedures, are associated with an increased risk of subsequent stroke, dementia and cognitive decline. 14.74], p=0.012).
Stroke, Volume 56, Issue Suppl_1 , Page ATMP76-ATMP76, February 1, 2025. Results:The rate of periprocedural stroke and/or death was significantly higher in patients who underwent CAS compared with CEA at 7 days or less after the qualifying event (5.4% versus 2.0%, p=0.68), at 15-30 days (5.1%
Stroke, Volume 56, Issue Suppl_1 , Page ATMP11-ATMP11, February 1, 2025. Introduction:Moyamoya disease (MMD) is a rare cerebrovascular disease causing nonatherosclerotic intracranial arterial stenosis in children and young adults. However, this variant is rarely found in patients of other ethnicity. vs. 5.7%, P=0.007).
Stroke, Volume 56, Issue Suppl_1 , Page ADP39-ADP39, February 1, 2025. We used the ICD-10 to identify patients hospitalized with diagnosis of stroke, TIA, or retinal ischemia with stenosis of carotid artery who underwent CAS or CEA. There was no difference in post-operative stroke and/or death (10.7%
Stroke, Volume 56, Issue Suppl_1 , Page A98-A98, February 1, 2025. The log-rank test demonstrated that patients with the mutation had a higher risk of progression to MMD (P =0.007), stenosis progression (P =0.010), and symptomatic cerebral infarction or hemorrhage (P =0.026). 95% CI, 2.13731;P= 0.001).
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