2025, Risk Factors and Stenosis - Cardiovascular Update

Recurrent polymorphic ventricular tachycardia without chest pain: an unusual presentation of focal coronary artery spasm

The British Journal of Cardiology

MARCH 4, 2025

This case report describes an atypical presentation of CAS in a 68-year-old white British male with cardiovascular risk factors. Coronary angiography identified moderate stenosis of the right coronary artery (RCA), without significant flow restriction by invasive pressure wire interrogation.

Chest Pain

Chest Pain Tachycardia Angina Arrhythmia

Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

FEBRUARY 3, 2025

tim.hodson Mon, 02/03/2025 - 12:30 January 29, 2025 Roche announced today that the Tina-quant Lipoprotein (a) Gen.2 Tsimikas S and Marcovina S, Ancestry, Lipoprotein(a), and Cardiovascular Risk Thresholds: JACC Review Topic of the Week , J Am Coll Cardiol. measuring lipoprotein (a), or Lp(a), in nanomoles per liter (nmol/L).

Cardiovascular Disease

Cardiovascular Disease Aortic valve Biomarkers Innovation

Abstract TP293: Association Between Aortic Arch Type and Lateralization of Subclavian Artery Stenosis: An Observational Cohort Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP293-ATP293, February 1, 2025. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4% vs 2.9%, p < 0.001).

Stenosis

Stenosis Aortic Atherosclerosis Risk Factors

Webinars

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Abstract TP318: Comparison of Lipid-Lowering Therapies Regimens and LDL-C Profiles in Patients with Asymptomatic versus Acute Symptomatic Atherosclerotic Carotid Stenosis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025. Introduction:Elevated Low-Density-Lipoprotein Cholesterol (LDL-C) blood levels are a risk factor for atherosclerosis. Lipid-lowering therapies mitigate the risk of atherothrombotic events. were asymptomatic and 40.2% acute symptomatic.

Stenosis

Stenosis Atherosclerosis Cholesterol Ischemia

Abstract TP220: Per-segment Evaluation of Atherosclerostic Stenosis of Intracranial Internal Carotid Artery: A hospital-based cross-sectional study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP220-ATP220, February 1, 2025. Background:The uneven distribution of intracranial atherosclerotic stenosis (ICAS) along the internal carotid artery (ICA) had been described in early clinicopathological studies, yet related, large-scale data is lack despite the widespread utilization of angiography.

Stenosis

Stenosis Hospital Atherosclerosis Risk Factors

Abstract WP347: Evaluating Brain Microvascular Endothelial Cell Dysfunction to Stenosis in a Tissue-Engineered Model of the Blood-Brain Barrier

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP347-AWP347, February 1, 2025. Ischemic stroke, a heterogeneous disease with various etiological subtypes and risk factors, places stress on the BBB. To model stenosis, a microactuator was mounted on a 3D printed platform and connected to a capillary tube (~1 mm diameter).

Stenosis

Stenosis Physiology Risk Factors Stroke

Abstract WP276: Association Between Vertebral Artery Hypoplasia and Atherosclerotic Stenosis of Subclavian Artery, Vertebral Artery and Basilar Artery: An Observational Cohort Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2025. We aimed to investigate the association between VAH and atherosclerotic stenosis of subclavian artery (SA), vertebral artery (VA) and basilar artery (BA) based on digital subtraction angiography (DSA).Methods:In VAH and stenosis degree of the artery (i.e.,

Stenosis

Stenosis Atherosclerosis Risk Factors Stroke

Abstract WP56: Dental Flossing associated with reduced White Matter Hyperintensity and Intracranial Atherosclerosis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP56-AWP56, February 1, 2025. In this study, we evaluated the relationship between flossing and ICAS, defined as 50% stenosis. These results emphasize the importance of dental flossing in reducing the rates of CSVD and moderately severe ICAS, both known risk factors for ischemic stroke.

Atherosclerosis

Atherosclerosis Stenosis Education Risk Factors

Abstract WP203: Ipsilateral Hemodynamic Failure of Extracranial Internal Carotid Artery is Associated with Severe Middle Cerebral Artery Atherosclerosis——a 4D Flow MRI Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. Introduction:The middle cerebral artery (MCA) is the most common site for inrtacranial atherosclerotic stenosis. Demographic data, risk factors and the history of ischemic stroke of all patients were recorded. 21.35), p<0.001).Conclusions:Both

Atherosclerosis

Atherosclerosis Stenosis Risk Factors BMI

Abstract 98: RNF213 Mutation Associated with the Progression from Middle Cerebral Artery Steno-occlusive Disease to Moyamoya Disease

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A98-A98, February 1, 2025. Although MCAD can progress to MMD, the extent to which patients actually progress and the risk factors for this progression have not been fully elucidated.Methods:We retrospectively reviewed patients with MCAD who underwentRNF213genotyping.

Stenosis

Stenosis Risk Factors Hemorrhage Stroke

Abstract TMP12: Artificial Intelligence-estimated Probability of Aortic Stenosis Is an Independent Predictor of Major Adverse Cardiac Events in Patients with Carotid Artery Disease After Carotid Endarterectomy

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP12-ATMP12, February 1, 2025. Background:Atherosclerotic carotid artery disease is associated with a high risk of major adverse cardiac events (MACE) even with optimal risk factor management and surgical interventions such as carotid endarterectomy (CEA).

Stenosis

Stenosis Aortic Electrocardiogram Risk Factors

Abstract TP222: Impaired Distal Perfusion as a Predictor of Stroke Recurrence in Intracranial Atherosclerosis: A Single-Center Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP222-ATP222, February 1, 2025. We determined associations of baseline demographics, vascular risk factors, clinical, laboratory variables, imaging variables, and in-hospital treatments with study outcome. The study outcome was recurrent ischemic stroke by day 30.

Stroke

Stroke Strokes Atherosclerosis Stenosis

Abstract WP351: Severely diminished collateral formation and incomplete recovery of cerebral perfusion in aging mice after unilateral common carotid artery occlusion

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP351-AWP351, February 1, 2025. Collateral development plays an important role in maintaining cerebral blood flow (CBF) in the presence of critical stenosis or occlusion of large cerebral arteries. Age is a non-modifiable risk factor for ischemic stroke associated with collateral rarefaction.

Stenosis

Stenosis Risk Factors Stroke Strokes

Abstract TP178: Investigation of Computed Tomography Perfusion Imaging in Predicting Hyperperfusion Phenomenon After Carotid Artery Stenting

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP178-ATP178, February 1, 2025. Background:Hyperperfusion phenomenon (HPP) constitutes a significant risk factor for adverse outcomes following carotid artery stenting (CAS).

Stents

Stents Stent Stenosis Risk Factors

Trial Results: Low-Dose Colchicine HelpsTreat Cardiovascular Disease

DAIC

MARCH 31, 2025

tim.hodson Mon, 03/31/2025 - 10:26 March 31, 2025 AGEPHA Pharma USA, LLC, has released clinical data that provides new information about how low-dose colchicine, 0.5 mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease.

Cardiovascular Disease

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack

Trial Results: Low-Dose Colchicine Helps Treat Cardiovascular Disease

DAIC

MARCH 31, 2025

tim.hodson Mon, 03/31/2025 - 10:26 March 31, 2025 AGEPHA Pharma USA, LLC, has highlighted clinical data that provides new information about how low-dose colchicine, 0.5 mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease.

Cardiovascular Disease

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack

Abstract TP42: Chronic cerebral hypoperfusion impairs brain iron metabolism in aged mice

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP42-ATP42, February 1, 2025. Introduction:Aging and chronic cerebral hypoperfusion (CCH) are major risk factors for Vascular contribution to cognitive impairment and dementia (VCID), which is a heterogeneous group of disorders characterized by cognitive deficits secondary to cerebrovascular pathology.

Dementia

Dementia Stenosis Risk Factors Stroke

Abstract TMP98: Low-dose Rivaroxaban plus Antiplatelet Treatment in Patients With Symptomatic Intracranial Atherosclerotic Stenosis：A Prospective Observational Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP98-ATMP98, February 1, 2025. Background:The secondary prevention of symptomatic intracranial atherosclerotic stenosis (sICAS) remains a significant challenge.

Atherosclerosis

Atherosclerosis Stroke Strokes Stenosis

The eye as a window to CVD: case series and literature review of retinal ischaemic perivascular lesion (RIPL)

The British Journal of Cardiology

FEBRUARY 4, 2025

We obtained a thorough medical history to identify risk factors and CVD. The most common risk factor was type 2 diabetes mellitus (90.9%), followed by hypertension (81.9%). and carotid artery stenosis in 8.3%. A diagnosis of arrhythmia was determined in 36.4%

Coronary Artery Disease

Coronary Artery Disease Risk Factors Cardiovascular Disease Stenosis

Chest pain and this ECG. Angiogram totally normal. Is this myocarditis?

Dr. Smith's ECG Blog

APRIL 13, 2025

Coronary microvascular dysfunction Coronary dissection Read more about MINOCA and its etiologies here: [link] == MY Comment , by K EN G RAUER, MD ( 4/12 /2025 ): == Today's case brings up several important points regarding the entity known as, "MINOCA" ( = MI with N on- O bstructive C oronary A rteries ). As I wrote in that Nov.

Chest Pain

Chest Pain Embolism STEMI Plaque

5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC)

Cardiometabolic Health Congress

NOVEMBER 14, 2024

42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. Additionally, 10% of the global population suffers from chronic kidney disease , with diabetes and hypertension as significant risk factors. In the U.S.,

CME

CME Obesity Heart Failure Biomarkers

Recurrent polymorphic ventricular tachycardia without chest pain: an unusual presentation of focal coronary artery spasm

Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

Abstract TP293: Association Between Aortic Arch Type and Lateralization of Subclavian Artery Stenosis: An Observational Cohort Study

Webinars

Abstract TP318: Comparison of Lipid-Lowering Therapies Regimens and LDL-C Profiles in Patients with Asymptomatic versus Acute Symptomatic Atherosclerotic Carotid Stenosis

Abstract TP220: Per-segment Evaluation of Atherosclerostic Stenosis of Intracranial Internal Carotid Artery: A hospital-based cross-sectional study

Abstract WP347: Evaluating Brain Microvascular Endothelial Cell Dysfunction to Stenosis in a Tissue-Engineered Model of the Blood-Brain Barrier

Abstract WP276: Association Between Vertebral Artery Hypoplasia and Atherosclerotic Stenosis of Subclavian Artery, Vertebral Artery and Basilar Artery: An Observational Cohort Study

Abstract WP56: Dental Flossing associated with reduced White Matter Hyperintensity and Intracranial Atherosclerosis

Abstract WP203: Ipsilateral Hemodynamic Failure of Extracranial Internal Carotid Artery is Associated with Severe Middle Cerebral Artery Atherosclerosis——a 4D Flow MRI Study

Abstract 98: RNF213 Mutation Associated with the Progression from Middle Cerebral Artery Steno-occlusive Disease to Moyamoya Disease

Abstract TMP12: Artificial Intelligence-estimated Probability of Aortic Stenosis Is an Independent Predictor of Major Adverse Cardiac Events in Patients with Carotid Artery Disease After Carotid Endarterectomy

Abstract TP222: Impaired Distal Perfusion as a Predictor of Stroke Recurrence in Intracranial Atherosclerosis: A Single-Center Study

Abstract WP351: Severely diminished collateral formation and incomplete recovery of cerebral perfusion in aging mice after unilateral common carotid artery occlusion

Abstract TP178: Investigation of Computed Tomography Perfusion Imaging in Predicting Hyperperfusion Phenomenon After Carotid Artery Stenting

Trial Results: Low-Dose Colchicine HelpsTreat Cardiovascular Disease

Trial Results: Low-Dose Colchicine Helps Treat Cardiovascular Disease

Abstract TP42: Chronic cerebral hypoperfusion impairs brain iron metabolism in aged mice

Abstract TMP98: Low-dose Rivaroxaban plus Antiplatelet Treatment in Patients With Symptomatic Intracranial Atherosclerotic Stenosis：A Prospective Observational Study

The eye as a window to CVD: case series and literature review of retinal ischaemic perivascular lesion (RIPL)

Chest pain and this ECG. Angiogram totally normal. Is this myocarditis?

5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC)

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