Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP3-ADP3, February 1, 2025. hour window, and reperfusion through thrombolysis has been shown to enhance functional outcomes in patients with salvageable brain tissue beyond this timeframe.Objective:The aim of this study is to assess the efficacy and safety of thrombolysis administered more than 4.5

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP8-ATP8, February 1, 2025. A good clinical outcome (mRS 90day 2) was achieved by 61.4%. Introduction:Treatment of acute stroke has its clear rules and established standards. Improvement occurred in 70.5% of patients. Mortality was 15.9%. The incidence of intracerebral hemorrhage was 9.1%

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A4-A4, February 1, 2025. Introduction:The tenecteplase versus standard of care for minor ischemic stroke with proven occlusion (TEMPO-2) trial showed that patients presenting with minor deficits up to 12 h do not benefit from intravenous thrombolysis. mg/kg) or non-thrombolytic standard of care.

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP9-AWP9, February 1, 2025. The effectiveness and safety of intravenous thrombolysis (IVT) for acute ischemic stroke in these cases, particularly those involving large vessel occlusions, are debated. Background:Acute ischemic stroke can result from extracranial arterial dissection.

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP20-ATP20, February 1, 2025. The primary outcome was 3-month functional outcome by modified Rankin scale (mRS). Additionally, 213 patients (18.9%) experienced END.

Thrombolysis 40

Thrombolysis Stroke Strokes Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP1-ADP1, February 1, 2025. Whether intravenous thrombolysis (IVT) is safe and effective for acute ischemic stroke (AIS) patients with CAA is largely unknown.Methods:This was an explorative analysis of a nationwide database of hospitalizations in the United States. 4.16], p=0.001).

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP253-AWP253, February 1, 2025. Background and Aims:Endovascular treatment (EVT) alone has been confirmed to be non-inferior to intravenous thrombolysis (IVT) followed with EVT in acute ischemic stroke (AIS) due to large-vessel occlusion of the anterior circulation.

Thrombolysis 40

Thrombolysis Stroke Strokes Stent 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP26-ATMP26, February 1, 2025. Introduction:Telestroke has the potential to revolutionize acute stroke treatment by improving access to optimal stroke care, including time-sensitive care such as thrombolysis. presented 4 hours of last known well, no contraindications to thrombolysis).

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A2-A2, February 1, 2025. Conclusion:Our results indicate a beneficial impact of IVT on the clinical outcomes of EVT in AIS-LVO patients with LII regarding functional outcomes and early neurological improvement. More studies of larger sample sizes are needed to corroborate such results.

Thrombolysis 40

Thrombolysis Hemorrhage Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP259-ATP259, February 1, 2025. Despite successful reperfusion, many patients still have unfavorable outcomes even in the presence of favorable arterial collaterals. These patients were dichotomized into favorable (mRS 0-2) and unfavorable outcome (mRS 3-6) groups.

Outcomes 40

Outcomes Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP8-AWP8, February 1, 2025. Introduction:Current guidelines recommend 24-hours of high-intensity monitoring (HIM) for acute ischemic stroke patients post-intravenous thrombolysis (IVT) due to risk of bleeding complications including symptomatic intracranial hemorrhage (sICH).

Thrombolysis 40

Thrombolysis ICU Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP115-ATP115, February 1, 2025. Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT).

Thrombolysis 40

Thrombolysis Stroke Strokes Quality of Life 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP87-ATP87, February 1, 2025. Background:Early prediction of functional outcome after rtPA helps clinicians in prognostic conversations with stroke patients and their families. modified Rankin Scale (mRS) at one month, classified into good (mRS 2) and poor (mRS 5) outcomes was noted.

Thrombolysis 40

Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP79-ATMP79, February 1, 2025. Introduction:Previous evidence indicated that transcranial doppler (TCD) parameters were associated with functional outcome in large vessel occlusion stroke (LVOS) patients who undergo mechanical thrombectomy (MT).

Outcomes 40

Outcomes Thrombolysis Stroke Strokes 40

Circulation: Cardiovascular Interventions

JANUARY 20, 2025

Circulation: Cardiovascular Interventions, Volume 18, Issue 1 , Page e014499, January 1, 2025. BACKGROUND:The aim of this study was to examine the impact of early versus delayed catheter-based therapies (CBTs) on clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE).METHODS:This days;P=0.046).

Embolism 40

Embolism Pulmonary Outcomes Cardiac Arrest 40

Stroke Journal

DECEMBER 9, 2024

Stroke, Volume 56, Issue 1 , Page 183-189, January 1, 2025. We assessed the correlation of these parameters with infarct expansion, hemorrhagic transformation, and poor outcomes, defined as modified Rankin Scale scores of 4 to 6, at 3 months.RESULTS:A total of 65 cases were analyzed. Cerebral blood flow <45% (r=0.57;P<0.001)

Thrombolysis 68

Thrombolysis Stroke Strokes Hemorrhage 68

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP190-ATP190, February 1, 2025. We aimed to determine the relationship between the affected hemisphere (right or left) and differences in non-motor outcomes (pain, mood) in patients with acute intracerebral hemorrhage (ICH).

Quality of Life 40

Quality of Life Hemorrhage Outcomes Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AHUP1-AHUP1, February 1, 2025. Introduction:Identification of modifiable drivers of the disparity between neighborhood socioeconomic status (nSES) and stroke outcomes remains elusive. Variables were derived from BASIC, Redfin and the National Neighborhood Data Archive (NaNDA).

Stroke 40

Stroke Strokes Outcomes Quality of Life 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP53-ADP53, February 1, 2025. Introduction:Identification of modifiable drivers of the disparity between neighborhood socioeconomic status (nSES) and stroke outcomes remains elusive. Variables were derived from BASIC, Redfin and the National Neighborhood Data Archive (NaNDA).

Stroke 40

Stroke Strokes Outcomes Quality of Life 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP91-ATMP91, February 1, 2025. Demographic, clinical, radiographic, treatment and outcome data were collected via chart review and entered into a secure, HIPAA-compliant RedCAP database. Stroke presentation, treatment and outcomes are shown in Table 2.

Stroke 40

Stroke Strokes Outcomes Pediatrics 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP246-AWP246, February 1, 2025. This study aims to elucidate the outcomes and factors contributing to achieving excellent recanalization (mTICI 2c-3) versus successful recanalization (mTICI 2b) in MeVO stroke patients undergoing mechanical thrombectomy (MT).Methods:We

Stroke 40

Stroke Strokes Outcomes Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP24-ATP24, February 1, 2025. Introduction:Mobile Stroke Units (MSUs) are proven to shorten the time between stroke recognition and thrombolysis resulting to better patient outcomes and are deemed safe and cost-effective.

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A13-A13, February 1, 2025. The primary efficacy outcome was favorable functional outcome, defined as modified Rankin Scale (mRS) scores of 0-3 at one year. The patients were divided into two groups based on whether they received adjunctive intravenous Tirofiban therapy or not.

Circulation 40

Circulation Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP5-ADP5, February 1, 2025. Introduction:Outcomes after thrombolysis with alteplase (tPA) versus tenecteplase (TNK) prior to endovascular thrombectomy (EVT) have not been directly compared in real-world data (RWD). The rate of good functional outcomes was 35.1% The rate of ENI was 50.0%

Thrombolysis 40

Thrombolysis Hemorrhage Academic Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP139-AWP139, February 1, 2025. Background:Telestroke allows rapid assessment of patients presenting with acute stroke symptoms for intravenous thrombolysis or endovascular thrombectomy (EVT). vs 3.1%), a lower rate for good functional outcome at 90-days (35.6%

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP53-AWMP53, February 1, 2025. Background:Treatment options and outcomes in stroke also depends on pre-hospital delays. Compared to the patients who reached by non-EMS mode, patients who reached by EMS mode were more likely to receive intravenous thrombolysis (16% vs 44%,).

Hospital 40

Hospital Stroke Strokes Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP72-AWP72, February 1, 2025. The transition from Alteplase to Tenecteplase for AIS patients eligible for thrombolysis occurred on June 6, 2022. EHR Alteplase references were changed to thrombolysis. The percentage of door to thrombolysis<30 minutes improved from 23.3%

Stroke 40

Stroke Strokes Thrombolysis Nursing 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP84-ATP84, February 1, 2025. We gathered data on the availability of critical resources like thrombolysis, computerized tomography (CT), and neurology services at over 200 facilities. In the U.S., In the U.S.,

Stroke 40

Stroke Strokes Thrombolysis ICU 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP5-AWMP5, February 1, 2025. Several methods have been described to derive NNT for ordinal outcomes. Overall, the magnitude of treatment effect estimates rendered by Permutation methods were substantially lower than by Joint Outcome methods Table methods.

Blood Pressure 40

Blood Pressure Thrombolysis Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP245-AWP245, February 1, 2025. However, intravenous thrombolysis was performed more frequently in the non-user group than in the heparin group, and the apTT value after the procedure was higher in the heparin group than in the other groups(75.912.5 vs 21.3%, p=0.04).

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP129-ATP129, February 1, 2025. As such, patient factors associated with delays in care can influence outcomes after MT and lead to health inequities. Introduction:An equitable health system requires access to clinical advances across society. hours versus 8.1

Thrombolysis 40

Thrombolysis Stroke Strokes Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP95-AWMP95, February 1, 2025. In light of context we aim in this investigation to assess the outcomes of these treatments.Methods:This multinational, multicenter study analyzed data from the Multicenter Analysis of Distal Medium Vessel Occlusions: Effect of Mechanical Thrombectomy (MAD-MT) registry.

Stroke 40

Stroke Strokes Hemorrhage Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP248-AWP248, February 1, 2025. Introduction:Endovascular thrombectomy (EVT) is effective in treating acute ischemic stroke, with research showing improved functional outcomes compared to medical treatment alone. Safety outcomes included ICH and 90 days mortality.

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A127-A127, February 1, 2025. Primary outcome: door to needle (DTN) time of the APP versus neurology residents using quantile (median) regression adjusted for age, NIHSS and delays for treating hypertension. Patients treated greater than 4.5

Academic 40

Academic Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP43-ADP43, February 1, 2025. Some receive intravenous thrombolysis (IVT) before transfer, while others are transferred for further evaluation and possibly treatment at the CSC.

Stroke 40

Stroke Strokes Thrombolysis Academic 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP80-ATP80, February 1, 2025. Introduction:Delays in IV thrombolysis (IVT) via telestroke may occur because of limited access to direct communication between providers. Patients that developed disabling symptoms after arrival and with missing data were excluded.

Thrombolysis 40

Thrombolysis Hospital Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A58-A58, February 1, 2025. While intravenous thrombolysis is recommended within 4.5 to 24-hour time window, potentially offering improved functional outcomes without significant increase in sICH. Background:Acute ischemic stroke (AIS) is a leading cause of disability worldwide.

Stroke 40

Stroke Strokes Thrombolysis Hemorrhage 40