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The 2025 AHA Statistical Update is the product of a full years worth of effort in 2024 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members.
18, 2025 About 90% of U.S. adults meet the criteria for a newly recognized syndrome that comes from a combination of heart disease, kidney disease, type 2 diabetes and obesity.[1] DALLAS, Feb. 1] This cluster of chronic health conditions is called.
The January 2025 endocrinology month in review highlights the latest from the FDA, key drug price negotiations, and the latest updates to the obesity pipeline.
Nature Reviews Cardiology, Published online: 07 April 2025; doi:10.1038/s41569-025-01154-x Mariella Huaman and Carlos Toro-Huamanchumo discuss the 2013 study that provided crucial insights into the cardiac structural changes associated with obesity and challenged previously established paradigms.
Nature Reviews Cardiology, Published online: 28 January 2025; doi:10.1038/s41569-025-01129-y A new study shows how obesity can disrupt a cholesterol metabolism in a particular subset of metabolically protective regulatory T cells in visceral adipose tissue.
On-demand access is available now and will remain open until December 2025. Obesity: Learn about behavioral approaches, the latest in pharmacotherapy, and surgical interventions for managing obesity. When Will It Be Available? Make sure to mark your calendar so you can take full advantage of this extensive resource!
Stroke, Volume 56, Issue Suppl_1 , Page A51-A51, February 1, 2025. 1.13),P=0.26) was comparable between GLP-1RAs and placebo.Conclusion:GLP-1 RAs therapy was associated with an overall reduction in the risk of stroke and nonfatal stroke in T2DM and/or heart failure or obese patients. 1.00),P=0.05), hemorrhagic stroke (OR, 0.82(95%CI:
Stroke, Volume 56, Issue Suppl_1 , Page AWMP106-AWMP106, February 1, 2025. We further examined interactions between UACR and covariates including age, obesity, white vs other races, and education. However, the interaction term for obesity warranted a stratified analysis (p=0.08). 2.38, p=0.003). 2.38, p=0.003). 2.84, p=0.001).Conclusion:Increased
Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. Older adults with obesity and metabolic syndrome may have decreased elimination of the xylitol metabolite xylose, which may explain the higher observed risk of thrombosis and stroke in older adults who consume foods with sugar alcohols.
They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days. 2025 Feb;35(2):e70024. Scand J Med Sci Sports.
Aronne, MD , discussed advances in obesity pharmacology, while Virend K. Looking Ahead: The Future of Cardiorenal Metabolic Medicine For those unable to attend, on-demand access to the 19th Annual CMHC content will be available from December 2024 to December 2025. Experts like Louis J. Learn more now!
Stroke, Volume 56, Issue Suppl_1 , Page ATP131-ATP131, February 1, 2025. Introduction:Studies of racial and ethnic disparities in using intravenous thrombolytics (IVT) for stroke in large healthcare systems and specific US states are lacking. received IVT.
Stroke, Volume 56, Issue Suppl_1 , Page AWP141-AWP141, February 1, 2025. In unadjusted analysis, factors significantly associated with troponin testing were a triage complaint of chest pain, older age, higher mean systolic BP, hypertension, diabetes, obesity, stroke or TIA, congestive heart failure, or coronary disease.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP94-AWMP94, February 1, 2025. vs 4.6%), obesity (26.4% This study investigated patient co-morbidity trends to determine if these factors have led to better national patient outcomes.Methods:We performed a data search from the U.S. vs 7.9%), diabetes (33.6%
Stroke, Volume 56, Issue Suppl_1 , Page ATP319-ATP319, February 1, 2025. Nearly half (47%) of graded census tracts had persistent discrimination and tracts with persistent discrimination were younger, less non-Hispanic white, and had higher proportions of diabetes, obesity and hypertension (Table).
Stroke, Volume 56, Issue Suppl_1 , Page ATP229-ATP229, February 1, 2025. Comorbidities such as PAD, depression, and other mental health disorders predict readmission after elective CAS, while heart failure, AKI, CAD, COPD, CKD, lipid disorders, DM, obesity, anemia, cancer, and dementia are predictive after elective CEA.
Stroke, Volume 56, Issue Suppl_1 , Page AWP281-AWP281, February 1, 2025. The model consisted of six variables, and one point was awarded for each: atrial fibrillation, large artery atherosclerosis, large vessel occlusion, obesity, prior anti-hypertensive medication usage and if patients age was 18-39 or > 69.
tim.hodson Wed, 03/26/2025 - 14:25 March 17, 2025 Bayer recently announcedthat the U.S. 2 Most are balancing multiple comorbidities, such as obesity, diabetes, hypertension and chronic kidney disease (CKD). Accessed February 21, 2025. Accessed March 5, 2025. Accessed February 21, 2025. 4 Approximately 6.7
Lilly’s blockbuster GLP-1 tirzepatide appears poised to become the next major HFpEF drug, after topline results from the SUMMIT trial showed that it significantly improved both outcomes and symptoms among patients with heart failure with preserved ejection fraction and obesity.
Stroke, Volume 56, Issue Suppl_1 , Page A94-A94, February 1, 2025. The sample size includes three comorbidity models (Young mice, Aging mice, and diet-induced hyperglycemia/ obesity mice.Results:Infarct volumes were variable across the network but right-skewed at all sites. Imaging from 1766 mice was used in this study.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP107-ATMP107, February 1, 2025. 1.61), and obesity (OR: 1.51, 95% CI: 0.79-1.20) Objective:Late-life vascular health and cerebrovascular disease have been identified as potential risk factors for late-life depression (LLD). At midlife, 20.2% had 0 VRFs, 41.3% had 1 VRF, 27.2%
Stroke, Volume 56, Issue Suppl_1 , Page ATP328-ATP328, February 1, 2025. However, obesity (0.30, 0.11-0.85) Objective:The role of statins in the management of intracerebral hemorrhage (ICH) remains controversial. Patients with diabetes (aOR, 95% CI: 2.99, 1.25-7.15) 7.15) and those with a history of anticoagulant use (2.54, 1.00-6.43)
Stroke, Volume 56, Issue Suppl_1 , Page ATP309-ATP309, February 1, 2025. The prevalence odds of common stroke risk factors including hypertension, diabetes, and overweight/obesity were higher for NHB vs NHW subgroups (e.g., 1.28] for overweight/obesity; NHB men 18-44 y OR 2.33 [2.26-2.40] NHB women 18-44 y OR 2.71 [95% CI 2.63-2.79]
Stroke, Volume 56, Issue Suppl_1 , Page ATP301-ATP301, February 1, 2025. vs 49.8%, p=0.31), obesity (15.0% Background:Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is the most common hereditary stroke disorder due to pathogenic variants in the NOTCH3 gene on chromosome 19.
This trend may be attributed to an increase in drug overdose deaths and homicides, along with a slowdown in the decline of cardiovascular disease deaths, likely linked to rising obesity rates. With the COVID-19 pandemic, things got even worse. 2006;3:e260. Life expectancy at birth. Accessed Jan. Available here.
Stroke, Volume 56, Issue Suppl_1 , Page AWP310-AWP310, February 1, 2025. Smoking, diabetes, hypertension, obesity, Black race, age, low education, male sex, and APOEe4 were associated with an increased risk of dementia/no PD. Older age, APOEe4, male sex, and low education were significantly assoiated with an increased risk of PDD.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP109-ATMP109, February 1, 2025. In Stage II, aged mice, mice with high-fat diet-induced obesity, and spontaneously hypertensive rats were utilized. Each stage included 25% of the study population and efficacy/futility was determined after each stage.
SUMMIT Trial : Weekly subcutaneous tirzepatide showed significant reductions in CV death and HF-related events among patients with HFpEF and obesity. AHA announced a $12M investment in AI research, with an RFP slated for early 2025. Get the latest knowledge and practical tools in cardiometabolic health to improve your practice in 2025.
Tirzepatide Approval Date: December 19, 2024 Indication: Moderate to severe obstructive sleep apnea (OSA) in adults with obesity, combined with a reduced-calorie diet and increased physical activity.
Diabetes and Obesity Care Advancements New Technologies for Diabetes Management : The recent FDA approvals of various insulin delivery devices, including the Embecta patch pump for Type 2 diabetes , have expanded patient options. These findings strengthen the case for broader utilization of finerenone in heart failure management.
With an ever-growing incidence of obesity, diabetes and cardiovascular disease, compounded by overwhelmed health services, this principle remains central to healthcare policies today. Introduction In 1736, Benjamin Franklin declared that an ounce of prevention is worth a pound of cure. Diabetes has long been.
Welcome to 2025 and best wishes for a great academic journey to all readers. 24 and TCT 2024) Colchicine in AMI CLEAR SYNERGY (OASIS 9) (TCT 2024 and AHA 2024) Semaglutide Treatment Effect in People With Obesity and HFpEF and Diabetes Mellitus STEP-HFpEF DM (ACC.24) Thanks to ACC for compiling it.
One influential framework, the Carbohydrate-Insulin Model of Obesity, posits that high carbohydrate intake increases insulin secretion, which promotes fat storage and reduces fat oxidation. Eur J Nutr 64, 23 (2025). This model has fueled the belief that nighttime carbohydrate consumption may hinder body composition goals. Andreou, E.,
42% of adults are considered obese , increasing their risk of diabetes, hypertension, and cardiovascular issues. Key Takeaways: Natriuretic Peptides : Useful for diagnosing and monitoring heart failure, particularly HFrEF, but challenging to interpret in patients with obesity due to peptide deficiency. In the U.S.,
This signature effort for the World Health Organization (WHO) in 2025 will include working with governments, donors, and the health community to invest in proven, high-impact interventions to improve maternal and newborn health and survival. Healthy beginnings, hopeful futures is the theme for World Health Day, Monday, April 7.
In the Sunday Times of April 23 rd , 2017, this article appeared, entitled ‘ Kellogg’s smothers health crisis in sugar – The cereals giant is funding studies that undermine official warnings on obesity.’ The study, published in the Journal Obesity Facts relied on evidence from 14 studies. Just to choose a few paragraphs. ‘
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