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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

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FDA Accepts sNDA for Furosemide (Furoscix) in Chronic Kidney Disease

HCPLive

The sNDA for furosemide seeks to expand the indication to include the treatment of edema due to fluid overload in patients with CKD, with a PDUFA date of March 6, 2025.

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Pay attention to 4 health factors to prevent new heart syndrome

American Heart News - Heart News

18, 2025 About 90% of U.S. adults meet the criteria for a newly recognized syndrome that comes from a combination of heart disease, kidney disease, type 2 diabetes and obesity.[1] DALLAS, Feb. 1] This cluster of chronic health conditions is called.

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Top 5 FDA Approvals from Q1 2025

HCPLive

The first quarter of 2025 saw approvals in diabetes, depression, kidney disease, and pain, among others. Read more about high-impact approvals of Q1 now.

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FDA Approves Updated Label for Tryvio (aprocitentan)

DAIC

tim.hodson Wed, 04/09/2025 - 14:38 April 9, 2025 Idorsia Ltd recently announced that the US Food & Drug Administration (FDA), after having released Tryvio from its REMS (Risk Evaluation and Mitigation Strategy) requirement ( announced March 17, 2025 ), has now approved the updated label for Tryvio(aprocitentan). Hypertension.

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Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

DAIC

tim.hodson Wed, 01/08/2025 - 14:11 Jan. 8, 2025 Mineralys Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S.

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Ceramides aggravate atherosclerosis via G protein-coupled receptor signalling

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 26 March 2025; doi:10.1038/s41569-025-01149-8 A study published in Nature has identified two transmembrane G protein-coupled receptors that mediate extracellular-to-intracellular ceramide signalling and shows that blocking these receptors alleviates the atherosclerosis that is induced by a high-fat diet (..)