Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP87-AWMP87, February 1, 2025. Background:Complete recanalization, defined as modified Treatment in Cerebral Ischemia (mTICI) score of 2c or better, has been shown to be superior to mTICI 2b in terms of patient outcomes following stroke thrombectomy.

Stroke 40

Stroke Strokes Outcomes Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP26-ADP26, February 1, 2025. Our results suggest that the transcription of eSINE-RNAs represents a robust neuroprotective response to transient focal ischemia, thus positioning them as potential molecular targets for modulating post-stroke outcomes.

Stroke 40

Stroke Strokes Outcomes Ablation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP93-AWMP93, February 1, 2025. Total endovascular reconstruction (TER) is increasingly feasible but mid-term and long-term outcomes have not been reported.Methods:Data from all patients treated with carotid CTO treated with TER over the past 18years were collected in a database.

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Outcomes Stents Stent Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A48-A48, February 1, 2025. Remote ischemic conditioning (RIC) with transient ischemia and reperfusion applied to the arm has been shown to accelerate hematoma resolution in both animal and clinical studies. This trial is registered with ClinicalTrials.gov, NCT04657133.Results:Between mL (IQR 10.0-18.0).

Hemorrhage 40

Hemorrhage Outcomes Ischemia Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP39-ADP39, February 1, 2025. We used the ICD-10 to identify patients hospitalized with diagnosis of stroke, TIA, or retinal ischemia with stenosis of carotid artery who underwent CAS or CEA. We divided patients based on presence or absence of atrial fibrillation.

Atrial Fibrillation 40

Atrial Fibrillation Stents Stent Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP349-ATP349, February 1, 2025. Background:Inflammation, a key player in both acute and chronic cerebral ischemia, is activated in brain tissues by bilateral carotid stenosis (BCAS)- induced chronic cerebral hypoperfusion.

Dementia 40

Dementia Ischemia Stenosis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP368-ATP368, February 1, 2025. Thrombectomy, where occluded arteries are cannulated for mechanical clot removal, can restore blood flow and improve survival, but still leaves 1/3 of patients functionally dependent, largely due to secondary ischemia-reperfusion injury.

Stroke 40

Stroke Strokes Ischemia Outcomes 40

Dr. Smith's ECG Blog

MARCH 27, 2025

But it was interpreted as no acute ischemia and the patient was referred to cardiology as Non-STEMI. Cardiology: delayed cath = Non-STEMI Heres the interventional cardiology note describing the ECGs, management and outcome: He has had transitory peak T-waves, ST-segment elevation, and biphasic T-waves during recurrences of pain.

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STEMI Chest Pain Pericarditis Ischemia 80

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP20-AWMP20, February 1, 2025. Background:Neuronal circuitry remodeling which compromises excitatory and inhibitory neurons is critical to improve neurological outcome after stroke.

Stroke 40

Stroke Strokes Ischemia Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP233-ATP233, February 1, 2025. had ischemia progression (ASPECTS decay of 2 or more), and 16.1% 1.00) for imaging stability, ischemia progression, and vessel recanalization, respectively. hours from initial neuroimaging. of patients had stable imaging, 14.5% had vessel recanalization.

Stroke 40

Stroke Strokes Ischemia Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP359-AWP359, February 1, 2025. Background:Mechanical thrombectomy has been associated with improved outcomes in patients with acute ischemic stroke. However, not all patients with successful reperfusion experience good functional outcomes.

Biomarkers 40

Biomarkers Stroke Strokes Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP142-AWP142, February 1, 2025. Introduction:INTEREACT 4 demonstrated lowering blood pressure in the prehospital setting improves outcomes for patients with intracerebral hemorrhage (ICH) but worsens outcomes for acute cerebral ischemia (ACI).

Technology 40

Technology Hemorrhage Blood Pressure Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP398-AWP398, February 1, 2025. Background:White matter or axonal injury is a key predictor of long-term functional outcome following ischemic stroke in humans. However, this type of injury is significantly understudied in animal stroke research.

Stroke 40

Stroke Strokes Ischemia Research 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP247-ATP247, February 1, 2025. Due to the rarity of iatrogenic CeAD, existing literature on management and outcomes is limited. Most cases are managed medically without significant clinical complications or long-term negative outcomes.

Stents 40

Stents Stent Angioplasty Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A162-A162, February 1, 2025. Background:Preceding respiratory tract infections (RTIs) caused by bacteria or viruses are associated with worse stroke outcomes, likely due to an exaggerated inflammatory immune response, endothelial dysfunction, platelet activation, and coagulopathy. In contrast,S.

COVID-19 40

COVID-19 Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP6-ATP6, February 1, 2025. According to our clinic observation, patients with acute ischemic stroke (AIS) treated with T1 to prevent/cure post-stroke infection display favorable stroke outcome. Bothin vivoandex vivoexperiments revealed that T1 directly inhibited ischemia-induced neuronal death.

Ischemia 40

Ischemia Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP220-AWP220, February 1, 2025. We excluded trials that used TXA for longer than 3 days which causes delayed vasospasm, increasing the risk of cerebral ischemia. The primary outcomes were HE, 24-hour hemorrhagic volume change, 90-day mortality and poor functional outcome.

Hemorrhage 40

Hemorrhage Ischemia Outcomes Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP366-AWP366, February 1, 2025. Both Kdm6afl/fland Kdm5cfl/flmice had worse stroke outcomes compared to fl/y and CKO mice (Figure 1B). Keywords:Stroke, Aging,Kdm6a/5c, Microglia, Epigenetics, Ischemia, IRF

Stroke 40

Stroke Strokes Ischemia Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP7-AWMP7, February 1, 2025. Background and objectives:Remote ischemic conditioning during cerebral ischemia ( PerRIC ) represents a new protection paradigm. The primary outcome was a modified Rankin Scale ( mRS ) score <=2 at 90 days.

COVID-19 40

COVID-19 Stroke Strokes Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP213-AWP213, February 1, 2025. Intracerebral Hemorrhagic (ICH) stroke is the second most common type of stroke and its aftermath is often more severe than ischemia. In order to improve post ICH outcome, immediate therapeutic interventions should be administered.

Hemorrhage 40

Hemorrhage Stroke Strokes Electrophysiology 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP402-AWP402, February 1, 2025. In experimental models, normotensive Sprague-Dawley (SD) and Spontaneously Hypertensive Rats (SHR) show different susceptibilities and outcomes to ischemic stroke. Middle Cerebral Artery Occlusion was used to induce focal ischemia/reperfusion injury (I/R).

Hypertension 40

Hypertension Stroke Strokes Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP242-AWP242, February 1, 2025. We analyzed patient characteristics, clinical outcomes, and the presence of lesions on postprocedural diffusion-weighted imaging (DWI lesions).Results:A Typically, the right radial artery is used in neurointerventions. years, 83.7%, and 53.5%

Stents 40

Stents Stent Aortic Interventional Cardiology 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP9-AWMP9, February 1, 2025. Background:Remote ischemic conditioning (RIC) with transient cycles of limb ischemia and reperfusion is a safe and promising neuroprotective therapy in acute ischemic stroke (AIS).

Stroke 40

Stroke Strokes Ischemia Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP28-ADP28, February 1, 2025. Background:Microglia-mediated inflammatory response directly affects ischemic stroke outcome. Autophagy is crucial in inflammatory response after cerebral ischemia.

Stroke 40

Stroke Strokes Ischemia Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP163-ATP163, February 1, 2025. Modified Treatment in Cerebral Ischemia (mTICI) score was used to determine reperfusion status, with mTICI > 2b considered successful. female) met inclusion criteria. No radiologic features were associated with successful reperfusion (Table 2).Conclusion:Multiphase

Document 40

Document Circulation Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP31-ADP31, February 1, 2025. The primary outcome was the presence of perfusion scotoma defined as ICuV 10mL. Introduction:CT perfusion maps (CTP) can estimate the ischemic core in acute ischemic stroke based on distinctive cerebral blood flow (CBF) thresholds.

Ischemia 40

Ischemia Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A34-A34, February 1, 2025. Tau PET demonstrated the highest uptake of 18F-THK-5351 at ischemia core. Tract-specific WM reductions correlated with infarct volume and functional outcomes 3 month poststroke. Introduction:Neuroinflammation plays a major role in post-stroke neuronal injury.

Stroke 40

Stroke Strokes Ischemia Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP119-ATMP119, February 1, 2025. MicroRNAs (miRNAs) play critical roles in the pathologies of cerebral ischemia and dementia. Background:Vascular cognitive impairment (VCI) is the second most frequent subtype of dementia following Alzheimer's disease.

Dementia 40

Dementia Cholesterol Ischemia Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP30-ADP30, February 1, 2025. Background&Objectives:It remains unclear why unilateral proximal carotid artery occlusion (UCAO) causes benign oligemia, without progressing to cerebral infarction, in mice, yet leads to a wide variety of outcomes (asymptomatic-to-death) in humans.

Cholesterol 40

Cholesterol Ischemia Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP153-ATP153, February 1, 2025. Background:According to the 2023 guidelines for the management of patients with aneurysmal subarachnoid hemorrhages (SAH), early treatment of ruptured aneurysms reduces the risk of repeated bleeds and facilitates treatment of delayed cerebral ischemia.

Aneurysm 40

Aneurysm Hospital Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP26-AWP26, February 1, 2025. The factors that may affect neuropsychological outcomes after aSAH are not well characterized. Clinical variables, modified Rankin score (mRS) at discharge, hemorrhage volume, and the occurrence of vasospasm or new ischemia during hospitalization were collected.

Hemorrhage 40

Hemorrhage Aneurysm Quality of Life Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP357-AWP357, February 1, 2025. Introduction:The rapid recanalization of occluded vessels and the restoration of cerebral blood flow (CBF) are critical for the outcome of stroke. Reperfusion CBF did not predict tissue and behavioral outcomes.

Outcomes 40

Outcomes Laboratory Stroke Strokes 40

Cardiometabolic Health Congress

JANUARY 2, 2025

September 2024 Approvals Flurpiridaz F 18 Approval Date: September 27, 2024 Indication: A radioactive positron emission tomography (PET) tracer for imaging myocardial ischemia and infarction in adults with suspected or known coronary artery disease. To explore FDA approvals from January to July 2024, click here.

Coronary Artery Disease 52

Coronary Artery Disease Stents Stent Innovation 52

DAIC

JANUARY 13, 2025

tim.hodson Mon, 01/13/2025 - 16:24 A new studyreports persistent disparities in outcomes for people with peripheral artery disease (PAD) and its more severe form, chronic limb-threatening ischemia (CLTI) in the United States. Among 73,237 patients who underwent major lower extremity amputation, 55.1%

Peripheral Arterial Disease 52

Peripheral Arterial Disease Outpatient Ischemia Vascular Care 52

Dr. Smith's ECG Blog

MARCH 14, 2025

This case highlights how T-waves are very important in the assessment of ischemia and dynamic changes in acute coronary syndrome. I have often seen colleagues worry about T-wave inversions as a sign of ongoing ischemia. Here is evidence for this: Opiates are associated with worse outcomes in Myocardial Infarction. Am Heart J.

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Chest Pain STEMI Myocardial Infarction Ischemia 106

Dr. Smith's ECG Blog

MARCH 25, 2025

There is low voltage in the precordium which always makes reading ischemia harder. In ACS, chest pain is the warning sign of ongoing ischemia. Smith : As Willy says, and as we've said many times before, morphine will resolve pain without resolving ischemia. ECG 1 What do you think? To me, this ECG is not diagnostic.

Chest Pain 63

Chest Pain Ischemia Plaque Stents 63

Dr. Smith's ECG Blog

JANUARY 31, 2025

In this situation, even after the ischemia is relieved and myocardial blood flow is restored myocardial contractile function remains impaired for a variable period of time (usually days to a few weeks). This ECG and patient outcome is a reminder of why it is so important to recognize this ECG pattern. References: Kloner, R.

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STEMI Chest Pain Myocardial Infarction Ischemia 114