Remove 2025 Remove Hypertension Remove Kidney Disease
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FDA Approves Updated Label for Tryvio (aprocitentan)

DAIC

tim.hodson Wed, 04/09/2025 - 14:38 April 9, 2025 Idorsia Ltd recently announced that the US Food & Drug Administration (FDA), after having released Tryvio from its REMS (Risk Evaluation and Mitigation Strategy) requirement ( announced March 17, 2025 ), has now approved the updated label for Tryvio(aprocitentan). Hypertension.

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Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

DAIC

tim.hodson Wed, 01/08/2025 - 14:11 Jan. 8, 2025 Mineralys Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension, chronic kidney disease (CKD) and other diseases, hasannounced that the U.S.

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Albuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review

Circulation

Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025. Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidney disease, or heart failure, as well as among adults with few cardiovascular risk factors.

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Mechanistic Insights Into Redox Damage of the Podocyte in Hypertension

Hypertension Journal

Hypertension, Volume 82, Issue 1 , Page 14-25, January 1, 2025. Podocyte dysfunction, resulting from oxidative stress, dysregulated prosurvival signaling, or structural damage, can drive the development of proteinuria and glomerulosclerosis in hypertensive nephropathy.

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Abstract DP60: Molecular Mechanisms of Cerebral Microhemorrhage Formation in Chronic Kidney Disease

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ADP60-ADP60, February 1, 2025. Background:Chronic kidney disease (CKD) has emerged as an independent risk factor for cerebral microhemorrhages (CMH). adenine diet to induce CKD, or angiotensin II (ATII) via subcutaneous osmotic pumps to induce HTN and compared with control mice.

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Your Top Five Questions About CMHC On-Demand, Answered

Cardiometabolic Health Congress

On-demand access is available now and will remain open until December 2025. If you attended the 19th Annual Cardiometabolic Health Congress (CMHC), please reach out to info@cardiometabolichealth.org and we will provide you with a complimentary access code to this activity. When Will It Be Available?

CME 52
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Abstract WP294: Racial Disparities among the risk of Stroke and other clinical outcomes post Infective Endocarditis: A Propensity Matched Analysis

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP294-AWP294, February 1, 2025. Background:Racial disparities have been well described in cardiovascular disease. Patients were categorized into two groups, one with Black or African American and another with White race patients. Both groups were followed for 12 months.