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Stroke, Volume 56, Issue Suppl_1 , Page A125-A125, February 1, 2025. Introduction:Managing post-acute hemorrhagic stroke care is complex and necessitates close follow-up and coordination. Ninety-day modified Rankin Scale (mRS) evaluated functional outcomes analyzed using a proportional odds logistic regression.
Stroke, Volume 56, Issue Suppl_1 , Page ATP190-ATP190, February 1, 2025. Background:The prognostic significance of the affected hemisphere in hemorrhagic stroke remains uncertain. The association of ICH laterality with clinical outcomes was estimated using multiple linear regression models.
Stroke, Volume 56, Issue Suppl_1 , Page ATP205-ATP205, February 1, 2025. Introduction:Alzheimers Disease (AD), characterized by extracellular deposition of amyloid beta (A) plaques in brain tissue, is often comorbid with cerebral amyloid angiopathy, which carries an elevated risk of intracranial hemorrhage. andICD-10-CMcode G30.x.
Stroke, Volume 56, Issue Suppl_1 , Page AWP228-AWP228, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) volume and expansion are important predictors of clinical outcome. Recent results show volumetric thresholds for prediction of poor outcome differ based on the anatomic location (lobar vs deep) of the ICH.
Stroke, Volume 56, Issue Suppl_1 , Page ATP170-ATP170, February 1, 2025. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. Conclusions:WMD burden did not have an independent association with 90-day functional outcomes or hemorrhagic transformation in the DEFUSE 3 cohort.
Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The exposure was an incident diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage, subarachnoid hemorrhage, or subdural hemorrhage. The outcome was an incident diagnosis of dementia.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP18-ATMP18, February 1, 2025. Background and Issues:Timely identification and intervention are critical for positive outcomes in acute intracerebral hemorrhage (ICH) patients. Conclusions:Having measurable goals for ICH has demonstrated a significant improvement in outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page ATP343-ATP343, February 1, 2025. Background:Subarachnoid Hemorrhage (SAH) accounts for 2-7% of strokes and has high mortality and morbidity. The identified genes and networks may guide the search for potential biomarkers of outcome and novel treatment targets.
Stroke, Volume 56, Issue Suppl_1 , Page ADP8-ADP8, February 1, 2025. the 2023 calendar year, our comprehensive stroke metric for hemorrhagic stroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To We continue to assess compliance and project feasibility.We
Stroke, Volume 56, Issue Suppl_1 , Page AWP236-AWP236, February 1, 2025. Background:A novel inflammatory score has been validated for hematoma expansion and poor outcomes in patients with intracerebral hemorrhage. Inflammatory score was significantly higher in patients with hemorrhagic transformation.
Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025. Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical. Survivors had GFAP levels of 1.35 ng/mL, while deceased patients had levels of 1.94
Stroke, Volume 56, Issue Suppl_1 , Page AWP368-AWP368, February 1, 2025. Introduction:Oxidative stress plays an important role in both early brain injury and delayed cerebral ischemia after subarachnoid hemorrhage (SAH). In further studies, we will test how MnP-05 affects long-term outcomes of SAH. P<0.05, Fig.
Stroke, Volume 56, Issue Suppl_1 , Page AWP232-AWP232, February 1, 2025. Background:Intracerebral hemorrhage (ICH) is a critical neurological condition with high rates of mortality and morbidity. Accurate prediction of the clinical outcomes in ICH patients is essential for effective clinical management. and 47.8%, respectively.
Stroke, Volume 56, Issue Suppl_1 , Page ATP189-ATP189, February 1, 2025. Standardized studies are imperative to inform evidence-based clinical decisions and improve outcomes for individuals afflicted with intracranial hemorrhage. and a 95% confidence interval (CI) of 0.25-0.57 0.57 (p < 0.00001).
Stroke, Volume 56, Issue Suppl_1 , Page AWP220-AWP220, February 1, 2025. Background:Several studies have shown that tranexamic acid (TXA), an anti-fibrinolytic agent, may reduce hematoma expansion (HE) in intracerebral hemorrhage (ICH), but its therapeutic time window is unclear. mL; 95% CI -2.51; -0.09; p= 0.04; I2= 47%).
Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear.
Stroke, Volume 56, Issue Suppl_1 , Page A83-A83, February 1, 2025. Clinical and neuroimaging predictors of an unfavorable discharge outcome (modified Rankin score 4) were assessed in univariate and multivariable models.Results:Between 2003 and 2019, 1,791 patients were admitted with non-traumatic ICH.
Stroke, Volume 56, Issue Suppl_1 , Page AWP136-AWP136, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) leads to the highest mortality among stroke patients. ICH expansion causes worse outcomes, especially with anticoagulant-associated ICH.
Stroke, Volume 56, Issue Suppl_1 , Page A48-A48, February 1, 2025. Introduction:Supratentorial intracerebral hemorrhage (ICH) is a devastating stroke subtype with high mortality and morbidity, and hematoma clearance is a critical therapeutic target. This trial is registered with ClinicalTrials.gov, NCT04657133.Results:Between
Stroke, Volume 56, Issue Suppl_1 , Page AWMP80-AWMP80, February 1, 2025. Introduction:Stroke is a devastating complication of infective endocarditis (IE) and is associated with poor outcomes. Ischemic strokes accounted for 77.94% of cases, while hemorrhagic strokes occurred in 22.05% (n=68).
Stroke, Volume 56, Issue Suppl_1 , Page AWMP72-AWMP72, February 1, 2025. Direct-to-angiography workflow relies on CBCT to exclude intracranial hemorrhage (ICH) to determine treatment eligibility for intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT). Conclusion:CBCT had high specificity for ICH and hemorrhage types.
Stroke, Volume 56, Issue Suppl_1 , Page ATP203-ATP203, February 1, 2025. Introduction:Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, has been shown to reduce perihematomal edema in patients with acute intracerebral hemorrhage (ICH), but its effect on outcome was largely unclear. 2015 and Dec.
Stroke, Volume 56, Issue Suppl_1 , Page A30-A30, February 1, 2025. Background and objective:Perfusion imaging studies consistently show a substantially increased risk of hemorrhagic transformation (HT) in severely hypoperfused tissue.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP2-ATMP2, February 1, 2025. Introduction:Flow diversion (FD) is a minimally invasive treatment for unruptured intracranial aneurysms (UIA) and is often preferred over open cerebrovascular surgery; however, FD patients are at risk of post-procedural stroke and hemorrhage.
Stroke, Volume 56, Issue Suppl_1 , Page AWP215-AWP215, February 1, 2025. Background:FDA clearance of fully automated artificial intelligence (AI)-based software for quantifying intracerebral hemorrhage (ICH) volumes has the potential to meaningfully impact the acute management of hemorrhagic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP40-ATMP40, February 1, 2025. risk stratification for ICH patients is a critical gap in improving post-ICH outcomes. Socioeconomic deprivation was measured using the state-level Area Deprivation Index (ADI; high deprivation defined as ADI > 7).
Stroke, Volume 56, Issue Suppl_1 , Page ADP49-ADP49, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is associated with poor outcomes in part due to a lack of perceived sense of urgency. Imaging analyses were performed using 3D Slicer segmentation software. Results:Among 75 patients, meanSD age was 79.89.1
Stroke, Volume 56, Issue Suppl_1 , Page AWP155-AWP155, February 1, 2025. Patients were divided into those with strokes (ischemic or hemorrhagic) and those without strokes. Out of them, 0.066% (n=3935) patients were found to have ischemic stroke, while 1.8% (n= 109,470) patients had hemorrhagic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP114-ATMP114, February 1, 2025. Background:Anemia is a risk factor for worse intracerebral hemorrhage (ICH) outcomes, yet the underlying drivers remain unclear. Though anemia and inflammation are interrelated, it is unknown whether anemia influences inflammatory responses to ICH.
Stroke, Volume 56, Issue Suppl_1 , Page AWP82-AWP82, February 1, 2025. Patients with anticoagulant-related hemorrhage require rapid reversal to mitigate risk of hematoma expansion. Measuring time to reversal (TTR) data can facilitate critical quality improvement efforts towards improving outcome.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP79-AWMP79, February 1, 2025. Background and Purpose:The inflammatory response after ischemic and hemorrhagic stroke is associated with worse clinical outcomes through immune mediated production of pro- inflammatory cytokines. Of 25 enrolled patients, mean age was 65.8 (SD,
Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025. Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP4-ATMP4, February 1, 2025. Introduction:Early brain injury (EBI), a complex collection of pathophysiological processes occurring within 72 hours aneurysmal subarachnoid hemorrhage (aSAH), is the key link connecting the initial event to the delayed and long-term complications.
Stroke, Volume 56, Issue Suppl_1 , Page AWP211-AWP211, February 1, 2025. Inclusion criteria was a diagnosis of ischemic stroke or intracerebral hemorrhage (ICH). Introduction:Physical and occupational therapy are a standard of care for in-hospital stroke patients. Our model showed that NIHSS at admit (OR = 0.94, CL: 0.90-0.99,
Stroke, Volume 56, Issue Suppl_1 , Page AWP245-AWP245, February 1, 2025. Background and Aims:Previous studies indicated the usual dose heparin(5000 IU bolus followed by 500~1250 IU/h) during mechanical thrombectomy(MT) is associated with an increased risk of hemorrhagic conversion without beneficial effect. vs 21.3%, p=0.04).
Stroke, Volume 56, Issue Suppl_1 , Page ATMP52-ATMP52, February 1, 2025. Introduction:A recent randomized-controlled trial confirmed the value of minimally-invasive intracerebral hemorrhage (ICH) evacuation to improve outcomes in properly-selected patients.
Stroke, Volume 56, Issue Suppl_1 , Page AWP213-AWP213, February 1, 2025. Intracerebral Hemorrhagic (ICH) stroke is the second most common type of stroke and its aftermath is often more severe than ischemia. In order to improve post ICH outcome, immediate therapeutic interventions should be administered.
Stroke, Volume 56, Issue Suppl_1 , Page AWP315-AWP315, February 1, 2025. Moderate/severe alcohol consumption did not display clear negative effects on ICH- or cSVD-related characteristics or short-term outcomes. Despite being much younger, heavy drinkers have similar cSVD burden compared to none/mild users.
Stroke, Volume 56, Issue Suppl_1 , Page ATP9-ATP9, February 1, 2025. Hemorrhagic transformation (HT), a complication of IVT, is more frequent in acute hyperglycemia and diabetes (DM) and is associated with poor clinical outcomes. We previously reported better clinical outcomes in DM patients treated with TNK.
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