Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The exposure was an incident diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage, subarachnoid hemorrhage, or subdural hemorrhage. The outcome was an incident diagnosis of dementia.

Dementia 40

Dementia Hemorrhage Medicare Outpatient 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP18-ATMP18, February 1, 2025. Background and Issues:Timely identification and intervention are critical for positive outcomes in acute intracerebral hemorrhage (ICH) patients. Conclusions:Having measurable goals for ICH has demonstrated a significant improvement in outcomes.

Hemorrhage 40

Hemorrhage Blood Pressure Outcomes ICU 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP343-ATP343, February 1, 2025. Background:Subarachnoid Hemorrhage (SAH) accounts for 2-7% of strokes and has high mortality and morbidity. The identified genes and networks may guide the search for potential biomarkers of outcome and novel treatment targets.

Hemorrhage 40

Hemorrhage Outcomes Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP8-ADP8, February 1, 2025. the 2023 calendar year, our comprehensive stroke metric for hemorrhagic stroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To We continue to assess compliance and project feasibility.We

Hemorrhage 40

Hemorrhage Stroke Strokes Document 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP236-AWP236, February 1, 2025. Background:A novel inflammatory score has been validated for hematoma expansion and poor outcomes in patients with intracerebral hemorrhage. Inflammatory score was significantly higher in patients with hemorrhagic transformation.

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A85-A85, February 1, 2025. Background:Systolic blood pressure (SBP) fluctuation is linked to increased death or disability in intracerebral hemorrhage (ICH) patients. These findings suggest this time window is crucial for future interventions aimed at controlling SBP in ICH patients.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP368-AWP368, February 1, 2025. Introduction:Oxidative stress plays an important role in both early brain injury and delayed cerebral ischemia after subarachnoid hemorrhage (SAH). In further studies, we will test how MnP-05 affects long-term outcomes of SAH. P<0.05, Fig.

Hemorrhage 40

Hemorrhage Outcomes Blood Pressure Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025. Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical. Survivors had GFAP levels of 1.35 ng/mL, while deceased patients had levels of 1.94

Hemorrhage 40

Hemorrhage Biomarkers Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP232-AWP232, February 1, 2025. Background:Intracerebral hemorrhage (ICH) is a critical neurological condition with high rates of mortality and morbidity. Accurate prediction of the clinical outcomes in ICH patients is essential for effective clinical management. and 47.8%, respectively.

Hemorrhage 40

Hemorrhage Outcomes Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP189-ATP189, February 1, 2025. Standardized studies are imperative to inform evidence-based clinical decisions and improve outcomes for individuals afflicted with intracranial hemorrhage. and a 95% confidence interval (CI) of 0.25-0.57 0.57 (p < 0.00001).

Hemorrhage 40

Hemorrhage Pharmacology Hypertension Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP220-AWP220, February 1, 2025. Background:Several studies have shown that tranexamic acid (TXA), an anti-fibrinolytic agent, may reduce hematoma expansion (HE) in intracerebral hemorrhage (ICH), but its therapeutic time window is unclear. mL; 95% CI -2.51; -0.09; p= 0.04; I2= 47%).

Hemorrhage 40

Hemorrhage Ischemia Outcomes Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear.

Hemorrhage 40

Hemorrhage Cerebrovascular Disease Dementia Document 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A83-A83, February 1, 2025. Clinical and neuroimaging predictors of an unfavorable discharge outcome (modified Rankin score 4) were assessed in univariate and multivariable models.Results:Between 2003 and 2019, 1,791 patients were admitted with non-traumatic ICH.

Hemorrhage 40

Hemorrhage Dementia Hypertension Outcomes 40

Stroke Journal

JANUARY 26, 2025

Stroke, Volume 56, Issue 2 , Page e100-e100, February 1, 2025.

Blood Pressure 40

Blood Pressure Hemorrhage Hospital Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP136-AWP136, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) leads to the highest mortality among stroke patients. ICH expansion causes worse outcomes, especially with anticoagulant-associated ICH.

Hemorrhage 40

Hemorrhage Blood Pressure Academic Nursing 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A48-A48, February 1, 2025. Introduction:Supratentorial intracerebral hemorrhage (ICH) is a devastating stroke subtype with high mortality and morbidity, and hematoma clearance is a critical therapeutic target. This trial is registered with ClinicalTrials.gov, NCT04657133.Results:Between

Hemorrhage 40

Hemorrhage Outcomes Ischemia Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP80-AWMP80, February 1, 2025. Introduction:Stroke is a devastating complication of infective endocarditis (IE) and is associated with poor outcomes. Ischemic strokes accounted for 77.94% of cases, while hemorrhagic strokes occurred in 22.05% (n=68).

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP61-ATMP61, February 1, 2025. Introduction:Secondary brain injury following intracerebral hemorrhage (ICH) is largely driven by neuroinflammation, which is exacerbated by neutrophil infiltration and their release of neutrophil extracellular traps (NETs).

Hemorrhage 40

Hemorrhage Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP244-ATP244, February 1, 2025. Introduction:Although older patients with subarachnoid hemorrhage (SAH) are often preferentially treated with coiling, in practice, there are insufficient data to support a clear benefit of coiling in this population.

Embolism 40

Embolism Hemorrhage Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP142-AWP142, February 1, 2025. Introduction:INTEREACT 4 demonstrated lowering blood pressure in the prehospital setting improves outcomes for patients with intracerebral hemorrhage (ICH) but worsens outcomes for acute cerebral ischemia (ACI).

Technology 40

Technology Hemorrhage Blood Pressure Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP72-AWMP72, February 1, 2025. Direct-to-angiography workflow relies on CBCT to exclude intracranial hemorrhage (ICH) to determine treatment eligibility for intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT). Conclusion:CBCT had high specificity for ICH and hemorrhage types.

Hemorrhage 40

Hemorrhage Stroke Strokes Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP2-ATMP2, February 1, 2025. Introduction:Flow diversion (FD) is a minimally invasive treatment for unruptured intracranial aneurysms (UIA) and is often preferred over open cerebrovascular surgery; however, FD patients are at risk of post-procedural stroke and hemorrhage.

Aneurysm 40

Aneurysm Hospital Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP203-ATP203, February 1, 2025. Introduction:Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, has been shown to reduce perihematomal edema in patients with acute intracerebral hemorrhage (ICH), but its effect on outcome was largely unclear. 2015 and Dec.

Hemorrhage 40

Hemorrhage Hospital Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is commonly associated with poor neurologic outcomes. These biomarkers could facilitate timely interventions, potentially improving outcomes for stroke patients. Specifically, functional parameters (i.e.,

Biomarkers 40

Biomarkers Physiology Hemorrhage Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A30-A30, February 1, 2025. Background and objective:Perfusion imaging studies consistently show a substantially increased risk of hemorrhagic transformation (HT) in severely hypoperfused tissue.

Hemorrhage 40

Hemorrhage Stroke Strokes Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP215-AWP215, February 1, 2025. Background:FDA clearance of fully automated artificial intelligence (AI)-based software for quantifying intracerebral hemorrhage (ICH) volumes has the potential to meaningfully impact the acute management of hemorrhagic stroke.

Hemorrhage 40

Hemorrhage Stroke Strokes Research 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP155-AWP155, February 1, 2025. Patients were divided into those with strokes (ischemic or hemorrhagic) and those without strokes. Out of them, 0.066% (n=3935) patients were found to have ischemic stroke, while 1.8% (n= 109,470) patients had hemorrhagic stroke.

Cancer 40

Cancer Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP40-ATMP40, February 1, 2025. risk stratification for ICH patients is a critical gap in improving post-ICH outcomes. Socioeconomic deprivation was measured using the state-level Area Deprivation Index (ADI; high deprivation defined as ADI > 7).

Hemorrhage 40

Hemorrhage Quality of Life Nursing Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP49-ADP49, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is associated with poor outcomes in part due to a lack of perceived sense of urgency. Imaging analyses were performed using 3D Slicer segmentation software. Results:Among 75 patients, meanSD age was 79.89.1

Hemorrhage 40

Hemorrhage Academic Blood Pressure Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP375-AWP375, February 1, 2025. Objective:In clinical practice, initial neurological status such as impaired consciousness is believed to correlate with patient outcomes in subarachnoid hemorrhage (SAH).

Hemorrhage 40

Hemorrhage Outcomes Research Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP114-ATMP114, February 1, 2025. Background:Anemia is a risk factor for worse intracerebral hemorrhage (ICH) outcomes, yet the underlying drivers remain unclear. Though anemia and inflammation are interrelated, it is unknown whether anemia influences inflammatory responses to ICH.

Hemorrhage 40

Hemorrhage Diet Risk Factors Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP82-AWP82, February 1, 2025. Patients with anticoagulant-related hemorrhage require rapid reversal to mitigate risk of hematoma expansion. Measuring time to reversal (TTR) data can facilitate critical quality improvement efforts towards improving outcome.

Hemorrhage 40

Hemorrhage Stroke Strokes Document 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP79-AWMP79, February 1, 2025. Background and Purpose:The inflammatory response after ischemic and hemorrhagic stroke is associated with worse clinical outcomes through immune mediated production of pro- inflammatory cytokines. Of 25 enrolled patients, mean age was 65.8 (SD,

Exercise 40

Exercise Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP62-ATMP62, February 1, 2025. Background:Elevated blood pressure (BP) is common after Intracerebral Hemorrhage (ICH) and is linked with increased morbidity and mortality, partly due to hematoma expansion. The same was true for prehospital BP management in undifferentiated stroke.

Blood Pressure 40

Blood Pressure Hemorrhage Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025. Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH.

Atrial Fibrillation 40

Atrial Fibrillation Hemorrhage Risk Factors Kidney Disease 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP4-ATMP4, February 1, 2025. Introduction:Early brain injury (EBI), a complex collection of pathophysiological processes occurring within 72 hours aneurysmal subarachnoid hemorrhage (aSAH), is the key link connecting the initial event to the delayed and long-term complications.

Aneurysm 40

Aneurysm Hemorrhage Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP211-AWP211, February 1, 2025. Inclusion criteria was a diagnosis of ischemic stroke or intracerebral hemorrhage (ICH). Introduction:Physical and occupational therapy are a standard of care for in-hospital stroke patients. Our model showed that NIHSS at admit (OR = 0.94, CL: 0.90-0.99,

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Hemorrhage Hospital Stroke Strokes 40