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Stroke, Volume 56, Issue Suppl_1 , Page ADP50-ADP50, February 1, 2025. Background:Local angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, which contributes to the pathogenesis of subarachnoid hemorrhage (SAH). million patients with hypertension were assessed. female) [HR:0.94(0.91-0.97),
Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025. Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical.
Stroke, Volume 56, Issue Suppl_1 , Page ATP170-ATP170, February 1, 2025. Introduction:Cerebrovascular white matter disease (WMD) severity is linked to vascular risk factors like hypertension, hyperlipidemia, and diabetes. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page ATP189-ATP189, February 1, 2025. Contributing factors such as hypocholesterolemia and hypertension amplify the risk of ICH and subsequent hematoma expansion, underscoring the urgent need for effective interventions. and a 95% confidence interval (CI) of 0.25-0.57 0.57 (p < 0.00001).
Stroke, Volume 56, Issue Suppl_1 , Page ATP282-ATP282, February 1, 2025. The main risk factor is hypertension, and blood pressure (BP) control is crucial in the primary and secondary prevention of stroke. The 2020 AHA Guideline was used to define hypertension and target BP. Statistical analysis was performed using STATA/SE 17.0
Stroke, Volume 56, Issue Suppl_1 , Page ANS7-ANS7, February 1, 2025. Background and Purpose:Intracerebral and subarachnoid hemorrhages comprise roughly 15% of all strokes but have a higher risk of mortality and morbidity than ischemic strokes.
Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025. Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH.
Stroke, Volume 56, Issue Suppl_1 , Page AHUP13-AHUP13, February 1, 2025. Introduction:Intracerebral Hemorrhage (ICH) is a significant type of stroke, being the second most common and with a higher risk of mortality and morbidity compared to ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP63-ATMP63, February 1, 2025. Objectives:Spontaneous intracerebral hemorrhage (ICH) is caused by the rupture of small arterioles due to cerebral small vessel disease (SVD), commonly with hypertensive arteriolosclerosis (HTA) or cerebral amyloid angiopathy (CAA).
Stroke, Volume 56, Issue Suppl_1 , Page ANS1-ANS1, February 1, 2025. Background:The 2023 American Heart Association/American Stroke AssociationsGuideline for Management of Patients with Aneurysmal Subarachnoid Hemorrhage(SAH) support use of the Ottawa Rule to screen individuals at risk.
Stroke, Volume 56, Issue Suppl_1 , Page AWP188-AWP188, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) is an age-related cerebral small vessel disease that can lead to poor outcomes due to cerebral hemorrhage. The same applies to hypertensive cerebral small vessel disease (HTN-CSVD).
Stroke, Volume 56, Issue Suppl_1 , Page AWP60-AWP60, February 1, 2025. Background:Cerebral amyloid angiopathy (CAA), in which amyloid- (A) is deposited in cerebral and meningeal blood vessels, is associated with not only stroke but also cognitive dysfunction.
Stroke, Volume 56, Issue Suppl_1 , Page AWP279-AWP279, February 1, 2025. Introduction:Neurological complications in patients with infective endocarditis (IE), such as ischemic and hemorrhagic stroke, are well-described, serious complications of IE; however, predicting which patients are most likely to experience stroke remains uncertain.
Stroke, Volume 56, Issue Suppl_1 , Page ATP312-ATP312, February 1, 2025. Stroke within 30 days of surgical resection was identified based on the radiology read of MRI brain for ischemic stroke and CT brain for hemorrhagic stroke that was obtained as part of clinical care. Patients who had a stroke were older [mean (SD); 60.4
Stroke, Volume 56, Issue Suppl_1 , Page ATP314-ATP314, February 1, 2025. Patients were admitted between 2013-2021 for ischemic and hemorrhagic stroke and had seen a PCP/PCAPP (primary care physician/primary care advance practice provider) in a regional health system or affiliated outpatient clinics using the EPIC electronic health record.
Stroke, Volume 56, Issue Suppl_1 , Page A21-A21, February 1, 2025. of population, while hemorrhagic strokes accounted for 16.8%. Introduction:For stroke survivors, blood pressure (BP) reduction significantly lowers the risk of recurrence; a 10mmHg decrease in systolic BP is associated with a 20% risk reduction. Black race, 5.9%
Stroke, Volume 56, Issue Suppl_1 , Page A60-A60, February 1, 2025. We enrolled 30 follow-up patients with either an ischemic or hemorrhagic stroke. There was a moderately negative correlation between MoCA-sf scores and a history of hypertension (-0.48, p 0.007) and hyperlipidemia (-0.38, p 0.044).
Stroke, Volume 56, Issue Suppl_1 , Page AWP338-AWP338, February 1, 2025. The most common comorbidities were hyperlipidemia (93.3%) and hypertension (80%). From those, intraplaque hemorrhage was the most common feature (81.1%).Proteomic Introduction:Extracranial carotid artery pathology accounts for 15-20% of ischemic strokes.
Stroke, Volume 56, Issue Suppl_1 , Page A127-A127, February 1, 2025. Primary outcome: door to needle (DTN) time of the APP versus neurology residents using quantile (median) regression adjusted for age, NIHSS and delays for treating hypertension.
Stroke, Volume 56, Issue Suppl_1 , Page ADP42-ADP42, February 1, 2025. Introduction:The transitional period from hospital discharge to the community for stroke survivors is a vulnerable time as patients navigate healthcare systems with their new impairments.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2025. CMBs in lobar regions suggest cerebral amyloid angiopathy (CAA), which is sometimes accompanied by superficial siderosis (SS), while subcortical CMBs indicate hypertensive origins. CMB and SS presence and location were coded from T2* GRE sequences.
Stroke, Volume 56, Issue Suppl_1 , Page AWP336-AWP336, February 1, 2025. Background:Trimethylamine N-oxide (TMAO), a gut microbiome-derived metabolite trimethylamine-containing nutrients, is mechanistically linked to atherosclerosis progression and platelet aggregation, leading to cardiovascular disease.
Stroke, Volume 56, Issue Suppl_1 , Page ATP194-ATP194, February 1, 2025. Background&Aims:Intraventricular extension (IE) is associated with unfavorable prognosis among patients with intracerebral hemorrhage (ICH). However, factors associated with IE are unknown. IE was observed in 151 patients (34%).
Stroke, Volume 56, Issue Suppl_1 , Page AWP235-AWP235, February 1, 2025. However, there are few studies investigating the impact of insurance status on outcomes in patients with intracerebral hemorrhage (ICH).Methods:We Disparities in outcomes of patients with ischemic stroke have been associated with insurance coverage.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP70-ATMP70, February 1, 2025. Introduction and Objective:Lobar cerebral microbleed (CMB) is frequently found in patients with spontaneous intracerebral hemorrhage (ICH) and is closely linked to cerebral amyloid angiopathy (CAA) and risk of recurrent ICH. 4.19], p=0.282).
Stroke, Volume 56, Issue Suppl_1 , Page AWP234-AWP234, February 1, 2025. Introduction:Education, a key modifiable social determinant of health, plays a significant role in shaping outcomes related to ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP20-ATMP20, February 1, 2025. Data collection included demographics, risk factors, blood pressures (BPs), and other variables such as the National Institute of Health Stroke Score (NIHSS), presence and types of large vessel occlusion, and severity of the hemorrhage (symptomatic or asymptomatic).Results:The
Stroke, Volume 56, Issue Suppl_1 , Page ADP47-ADP47, February 1, 2025. Introduction:Chronic kidney disease (CKD) is a risk factor for intracerebral hemorrhage (ICH) and for worse outcomes following ICH. CMB volume as well as intracranial arterial calcification (IAC) volume were extracted using custom convolutional neural networks.
Stroke, Volume 56, Issue Suppl_1 , Page AWP334-AWP334, February 1, 2025. Background:There is an emerging understanding of stroke risk in patients with immune thrombocytopenia purpura (ITP) and immune thrombotic thrombocytopenia purpura (iTTP). Stroke occurrence was reported in the acute phase (7.9% and 45%) and chronic phase (91.8%
Stroke, Volume 56, Issue Suppl_1 , Page AWP316-AWP316, February 1, 2025. Background:We reported that cariogenic bacteriaStreptococcus mutansexpressing a collagen-binding protein Cnm on its bacterial surface is associated with the prevalence of intracerebral hemorrhage in retrospective observational studies. mutans(22.7% mutans(22.7%
Stroke, Volume 56, Issue Suppl_1 , Page AWP301-AWP301, February 1, 2025. Introduction:While intracranial hemorrhage (ICH) is uncommon in young adults (18-55), its incidence is on the rise. VRFs included hypertension, diabetes, kidney disease, smoking, drug or alcohol abuse, antithrombotic medication use, and sleep apnea.
Stroke, Volume 56, Issue Suppl_1 , Page AWP364-AWP364, February 1, 2025. The studies included various mouse strains (OF1 and C57BL/6), assessing the impact of diabetes and hypertension and sex-dependent responses on treatment outcomes. Introduction:In 2007, Orset et al.
Stroke, Volume 56, Issue Suppl_1 , Page AWP123-AWP123, February 1, 2025. Major risk factors included hypertension (12.5%), diabetes (5.20%), and dyslipidemia (3.12%), with 11.45% having autoimmune disorders. Background:Post-stroke fatigue is a common and debilitating issue, often linked to depression or neural damage.
Stroke, Volume 56, Issue Suppl_1 , Page AWP388-AWP388, February 1, 2025. Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. Cox regression was used to estimate the hazard ratio (HR) for incident stroke per doubling of EIC levels, and p-values were FDR corrected.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2025. CHIP is also considered a risk factor for subarachnoid hemorrhage. We induced intracranial aneurysms by a combination of elastase injection and DOCA-salt hypertension at 8 weeks later. C57BL/6 CD45.1+/CD45.2- TET2-/- cells and 90% CD45.1+/CD45.2-
Stroke, Volume 56, Issue Suppl_1 , Page ATP153-ATP153, February 1, 2025. Background:According to the 2023 guidelines for the management of patients with aneurysmal subarachnoid hemorrhages (SAH), early treatment of ruptured aneurysms reduces the risk of repeated bleeds and facilitates treatment of delayed cerebral ischemia.
Stroke, Volume 56, Issue Suppl_1 , Page ATP186-ATP186, February 1, 2025. Methods:AIS data was retrieved from the Norwegian Cognitive Impairment After Stroke study (Nor-COAST; NOR) and the Registry for Neurological Endpoints among patients with Ischemic and Hemorrhagic Stroke(REINAH; US).
Stroke, Volume 56, Issue Suppl_1 , Page ADP21-ADP21, February 1, 2025. Vascular risk factors like hypertension, diabetes, and hyperlipidemia are highly heritable, and persons with higher polygenic predisposition are less likely to achieve risk factor control.
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