Advances in Acute Ischemic and Hemorrhagic Stroke 2024
Stroke Journal
DECEMBER 19, 2024
Stroke, Volume 56, Issue 1 , Page 194-197, January 1, 2025.
Abstract WP51: Non-Traumatic Intracranial Hemorrhage and Risk of Incident Dementia
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The exposure was an incident diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage, subarachnoid hemorrhage, or subdural hemorrhage. 2.5), subarachnoid hemorrhage (HR, 2.0; years (IQR, 3.0-9.1),
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40 Abstract TP205: Alzheimer’s Disease and Risk of Intracranial Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP205-ATP205, February 1, 2025. Introduction:Alzheimers Disease (AD), characterized by extracellular deposition of amyloid beta (A) plaques in brain tissue, is often comorbid with cerebral amyloid angiopathy, which carries an elevated risk of intracranial hemorrhage. andICD-10-CMcode G30.x.
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Abstract DP8: Multifaceted Approach to Improving Hemorrhagic Stroke Scoring Performance
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ADP8-ADP8, February 1, 2025. the 2023 calendar year, our comprehensive stroke metric for hemorrhagic stroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To We continue to assess compliance and project feasibility.We
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Abstract WP236: Inflammartory score can predict the risk of hemorrhagic transformation after ischemic stroke
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP236-AWP236, February 1, 2025. Background:A novel inflammatory score has been validated for hematoma expansion and poor outcomes in patients with intracerebral hemorrhage. Inflammatory score was significantly higher in patients with hemorrhagic transformation.
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Abstract TP198: Alpha-Delta Ratio as an Acute Marker of Intracerebral Hemorrhage on Sub-galeal EEG
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP198-ATP198, February 1, 2025. Background:Spontaneous intracerebral hemorrhage (ICH) remains one of the most devastating forms of stroke, leaving many patients unresponsive with disorders of consciousness. However, there remain few options for continuous brain monitoring for ICH.
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40 Abstract WP222: External Validation of an Automated Hemorrhage Detection and Segmentation Algorithm on Follow-up CT scans in the AcT trial
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2025. Background and Aims:Machine learning models have shown promising potential for automated hemorrhage detection and segmentation, alleviating highly time-consuming manual contouring and facilitating rapid clinical diagnosis. 93.7%) and accuracy of 87.4%
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Abstract WP230: Neuroinflammation Biomarker in the Course and Prognosis of Hemorrhagic Strokes
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025. Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical.
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Hematoma Expansion in Intracerebral Hemorrhage: Time Is the Enemy
Stroke Journal
MARCH 23, 2025
Stroke, Volume 56, Issue 4 , Page 848-849, April 1, 2025.
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Abstract TP189: Statin Therapy and Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis of Mortality Risk
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP189-ATP189, February 1, 2025. Standardized studies are imperative to inform evidence-based clinical decisions and improve outcomes for individuals afflicted with intracranial hemorrhage. and a 95% confidence interval (CI) of 0.25-0.57 0.57 (p < 0.00001).
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Abstract TMP86: Stratifying risk of hemorrhage of pedatriac brain arteriovenous malformation using quantitative color-coded digital subtraction angiography and iflow analysis
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATMP86-ATMP86, February 1, 2025. Background:Pediatric brain arteriovenous malformation (bAVM) patients often present with intracranial hemorrhage. female), 47.5% (n=19) had a history of hemorrhage. Larger bAVM size was significantly associated with a lower likelihood of prior hemorrhage.
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Abstract TP187: Automated Assessment of Intracerebral Hemorrhage Volumes using the VIOLA tool Performs Similarly to ABC/2 in Predictive Modelling
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP187-ATP187, February 1, 2025. Introduction:Hemorrhage volume is a key prognostic characteristic for intracerebral hemorrhage (ICH) patients and has been included as an aspect of critical assessments, such as the ICH score. Hemorrhages assessed via VIOLA yielded a median of 23.70 [7.02-69.18]
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40 Abstract 139: Association between Cerebral Amyloid Angiopathy and Non-Traumatic Subdural Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear.
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40 Abstract WP390: Induced Subarachnoid Hemorrhage Leads To Cortical Infarcts In a Mouse Model Of Cerebral Amyloid Angiopathy
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP390-AWP390, February 1, 2025. Background:In cerebral amyloid angiopathy (CAA), amyloid- accumulates within blood vessel walls, leading to hemorrhagic lesions such as convexity subarachnoid hemorrhage (cSAH), microbleeds, and lobar intracerebral hemorrhage.
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Abstract WP220: Assessing the Therapeutic Time Window for Tranexamic Acid in Intracerebral Hemorrhage – A Systematic Review and Meta-analysis
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP220-AWP220, February 1, 2025. Background:Several studies have shown that tranexamic acid (TXA), an anti-fibrinolytic agent, may reduce hematoma expansion (HE) in intracerebral hemorrhage (ICH), but its therapeutic time window is unclear. to 0.97; p= 0.02; I2= 0%). mL; 95% CI -3.15
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40 Abstract TP201: Factors associated with development of venous thromboembolism in patients with intracranial hemorrhage.
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP201-ATP201, February 1, 2025. Background:Patients with intracerebral hemorrhage (ICH) are known to have a higher risk of venous thromboembolism (VTE) than patients with acute ischemic stroke, but the factors underlying this difference have not been clearly identified.
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Abstract TP137: Reducing Opioid Prescription for Subarachnoid Hemorrhage Headache Via a Dot-Phrase
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP137-ATP137, February 1, 2025. Subarachnoid hemorrhage can cause debilitating headaches, affecting 90% of these patients in the intensive care unit, and 40% at 32 month follow up.
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Abstract TP199: Impact of Statin Therapy on Functional Outcomes and Survival in Intracerebral and Subarachnoid Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP199-ATP199, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) are severe forms of stroke with high morbidity and mortality rates. These findings highlight the potential neuroprotective role of statins in hemorrhagic stroke.
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40 Transient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke
Stroke Journal
JANUARY 26, 2025
Stroke, Volume 56, Issue 2 , Page 285-293, February 1, 2025. Primary end points were 90-day readmission for ischemic stroke or hemorrhage and compared between men and women. BACKGROUND:Sex-specific differences in stroke risk factors, clinical presentation, and outcomes are well documented.
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Abstract 125: Factors Associated with Neuroscience Appointment Attendance in Hemorrhagic Stroke Patients and the Impact on Readmission and Functional Outcomes
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page A125-A125, February 1, 2025. Introduction:Managing post-acute hemorrhagic stroke care is complex and necessitates close follow-up and coordination. Outcome data was similar for patients with intracerebral hemorrhage and subarachnoid hemorrhage all p<0.05.Conclusion:Prehospital
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40 Abstract TMP5: The Impact of Enteral Nimodipine on Endothelial Cell Apoptosis in an Animal Subarachnoid Hemorrhage Model
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATMP5-ATMP5, February 1, 2025. Herein, we studied the effect of enteral nimodipine on endothelial apoptosis after subarachnoid hemorrhage (SAH).Methods:SAH However, the neuroprotective mechanism of nimodipine still remains unclear, and the effects of nimodipine remain ambiguous.
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40 Abstract 83: Prognostic Value of Cortical Superficial Siderosis Among Patients with Cerebral Amyloid Angiopathy-Associated Intracerebral Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page A83-A83, February 1, 2025. Introduction:The recent update (version 2.0) Introduction:The recent update (version 2.0)
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Abstract WP229: Cerebral Amyloid Angiopathy Prevalence and Associated Risk of Subsequent Ischemic and Hemorrhagic Stroke and Mortality in a Nationally Representative Sample
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP229-AWP229, February 1, 2025. CAA and ischemic and hemorrhagic stroke were identified using previously validated ICD-10 codes. 4.7), intracerebral hemorrhage (aHR, 32.1; 52.4), and subarachnoid hemorrhage (aHR, 9.5; 4.7), intracerebral hemorrhage (aHR, 32.1; 95% CI, 19.6-52.4),
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Abstract TP310: The Shifting Evidence for Statin Use in the Setting of Intracerebral Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP310-ATP310, February 1, 2025. Introduction:Intracerebral Hemorrhage (ICH) is associated with a high case fatality and survivors of ICH are at increased risk for ICH recurrence. Roughly 20-30% of patients with ICH take a statin at the time of ICH onset.
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Abstract TMP61: Ixodes ricinus-Contact Phase Inhibitor (Ir-CPI) reduces neutrophil-mediated injury and promotes recovery following intracerebral hemorrhage in a mouse model
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATMP61-ATMP61, February 1, 2025. Introduction:Secondary brain injury following intracerebral hemorrhage (ICH) is largely driven by neuroinflammation, which is exacerbated by neutrophil infiltration and their release of neutrophil extracellular traps (NETs).
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Abstract TP166: Refining Deep Learning Application Diagnostic Accuracy in Intracerebral Hemorrhage (ICH): Focus on Subtle Hemorrhage Detection
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP166-ATP166, February 1, 2025. Introduction:Deep-learning (DL)-based applications for Intracerebral Hemorrhage (ICH) detection on non-contrast computed tomography (NCCT) scans have demonstrated the potential to enhance diagnostic accuracy and efficiency amid the increasing radiologist workload.
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Abstract TP190: Intracerebral Hemorrhage Laterality and Associations with Mood and Quality of Life Outcomes: A MISTIE III Substudy
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP190-ATP190, February 1, 2025. Background:The prognostic significance of the affected hemisphere in hemorrhagic stroke remains uncertain.
Abstract WMP72: Diagnostic Accuracy of Cone-Beam CT for Acute Intracranial Hemorrhage in Suspected Ischemic Stroke Patients: A Systematic Review and Meta-analysis
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWMP72-AWMP72, February 1, 2025. Direct-to-angiography workflow relies on CBCT to exclude intracranial hemorrhage (ICH) to determine treatment eligibility for intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT). Conclusion:CBCT had high specificity for ICH and hemorrhage types.
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Abstract TMP88: Clinical Utility of Genetic Testing in Pediatric and Young Adult Hemorrhagic Stroke and Cerebrovascular Malformations
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATMP88-ATMP88, February 1, 2025. Cerebrovascular conditions included brain or spine AVM, cavernous malformation, cerebral aneurysm, Moya-Moya vasculopathy, and/or unexplained hemorrhagic stroke. Individuals with perinatal or isolated arterial ischemic stroke were not included.
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40 Abstract NS7: Time is Brain and Team is Brain! A Partnership to Improve Blood Pressure Control for Hemorrhagic Stroke Patients
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ANS7-ANS7, February 1, 2025. Background and Purpose:Intracerebral and subarachnoid hemorrhages comprise roughly 15% of all strokes but have a higher risk of mortality and morbidity than ischemic strokes.
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40 Abstract TP170: White Matter Disease Burden Not Independently Associated with Clinical Outcomes or Hemorrhagic Transformation in DEFUSE 3 Population
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP170-ATP170, February 1, 2025. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. Conclusions:WMD burden did not have an independent association with 90-day functional outcomes or hemorrhagic transformation in the DEFUSE 3 cohort.
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40 Abstract TP61: National Hemorrhagic Stroke Initiative: Ensuring Every Patient Receives Optimal Care
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP61-ATP61, February 1, 2025. Background:Intracerebral hemorrhage (ICH) constitutes 10% of all strokes and is the most fatal and debilitating subtype. Unlike ischemic stroke, treatment strategies for ICH have not advanced as rapidly, resulting in limited adoption of specialized care metrics.
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Abstract WP215: Reliability and Agreement of Artificial Intelligence and Semi-Autonomous Quantification of Anticoagulant-Related Supratentorial Intraparenchymal Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP215-AWP215, February 1, 2025. Background:FDA clearance of fully automated artificial intelligence (AI)-based software for quantifying intracerebral hemorrhage (ICH) volumes has the potential to meaningfully impact the acute management of hemorrhagic stroke.
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40 Abstract DP50: Angiotensin inhibition reduces the risk of subarachnoid hemorrhage in patients with hypertension
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ADP50-ADP50, February 1, 2025. Background:Local angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, which contributes to the pathogenesis of subarachnoid hemorrhage (SAH).
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Abstract DP4: When Does Clinical Worsening Begin in Symptomatic Intracranial Hemorrhage after Intravenous Thrombolysis?
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ADP4-ADP4, February 1, 2025. The most serious risk associated with IV thrombolytics is symptomatic intracranial hemorrhage (sICH). sICH was defined as a hemorrhage that caused an increase in NIHSS by 4 or more points.
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Abstract WP225: Fibrinogen Depletion and The Risk of Intracerebral Hemorrhage following Mechanical Thrombectomy
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP225-AWP225, February 1, 2025. Fibrinogen levels may drop after IVT, and a significant decrease in fibrinogen is associated with an increased risk of intracranial hemorrhage (ICH).
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40 Abstract TP210: Myelin in the Macrophage Response to Intracerebral Hemorrhage-Relevant Signals
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP210-ATP210, February 1, 2025. Introduction:Blood-derived macrophages become activated and contribute to a toxic environment in the brain after intracerebral hemorrhage (ICH). However, after three days, these macrophages become reparative and essential to tissue repair and recovery.
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Abstract 105: Long-term exposure to ambient air pollution, including ultrafine particles, increases ischemic and hemorrhagic stroke risk among women in the California Teachers Study cohort
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page A105-A105, February 1, 2025. Introduction:Ambient air pollution is linked to increased stroke risk, but it is unclear if associations apply to long-term exposures, equally to different stroke subtypes (ischemic versus hemorrhagic) and differ by pollutants. PM10, and PM0.1) ug/m3(range: 0.84-85.6).
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Abstract WP136: Implementation of a Standardized Timeout Procedure for Intracerebral Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP136-AWP136, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) leads to the highest mortality among stroke patients. ICH expansion causes worse outcomes, especially with anticoagulant-associated ICH.
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40 Abstract WP227: Physiological Magnetic Resonance Imaging Biomarkers for Early Detection of Microvascular Dysfunction in Acute Intracerebral Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is commonly associated with poor neurologic outcomes. Early intervention has been shown to improve patient prognosis, highlighting the necessity of sensitive biomarkers.
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40 Abstract TMP18: Establishing Aggressive Time Targets for the Identification and Treatment of Intracerebral Hemorrhage Improves Patient Outcomes
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATMP18-ATMP18, February 1, 2025. Background and Issues:Timely identification and intervention are critical for positive outcomes in acute intracerebral hemorrhage (ICH) patients.
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40 Abstract 30: Association between Time and Severe Hypoperfusion with Risk of Hemorrhagic Transformation in Thrombectomy Stroke Patients
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page A30-A30, February 1, 2025. Background and objective:Perfusion imaging studies consistently show a substantially increased risk of hemorrhagic transformation (HT) in severely hypoperfused tissue.
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40 Abstract TMP6: Intra-arterial Lidocaine Administration of Lidocaine in Middle Meningeal Artery for Treatment of Subarachnoid Hemorrhage-Related Headaches
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATMP6-ATMP6, February 1, 2025. Results:We observed improvement in severity of headaches of headache in all 7 subarachnoid hemorrhage patients.
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40 Abstract TP100: Predictors of Skilled Nursing Facility Length of Stay and Discharge after Aneurysmal Subarachnoid Hemorrhage
Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP100-ATP100, February 1, 2025. Introduction:Aneurysmal subarachnoid hemorrhage (aSAH) carries high morbidity and mortality. Intraventricular hemorrhage (OR 0, 95% CI 0-1.12, p=0.043), tracheostomy (OR=0.14, 95% CI 0.14-1.01, Discharged patients were younger (mean 63.311.5
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