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Physiology Friday #253: Low-carb Matches High-carb for Performance: Is it Time to Question the Obligatory Role of Glycogen for Endurance Exercise?

Physiologically Speaking

For decades, high-carbohydrate diets have been considered the gold standard for fueling endurance activities, largely due to their ability to optimize muscle glycogen stores. Advocates of low-carb diets argue that fat adaptation can enhance endurance by increasing fat oxidation. What’s this all mean? What’s this all mean?

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Physiology Friday #264: Have We Been Fooled Into Thinking Exercise Improves Sleep?

Physiologically Speaking

Exercise has never been so en vogue—for better or worse. By worse, I mean we often discuss exercise as a panacea. Just exercise. Nowhere is this more apparent than in the realm of sleep, where exercise is often promoted as a way to help people sleep better, longer, and more deeply. Overweight? Or does it?

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Physiology Friday #254: Fueling for Performance and Health: Lessons from a Recent Low-Carb vs. High-Carb Study in Athletes

Physiologically Speaking

Last week, I wrote about a new study comparing low-carb and high-carb diets for endurance performance. 1 If you want the tl;dr, here it is: After 6 weeks on either a low- or high-carb diet, athletes experienced similar performance outcomes during a time-to-exhaustion test , a result that vindicates low-carb diets once and for all.

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Physiology Friday #265: Should Carbohydrate Intake During Exercise Be Personalized? A New Study Suggests Yes.

Physiologically Speaking

Wouldn’t someone who’s larger need more carbs during exercise? That’s not what previous data indicate, showing a lack of an association between body size and peak glucose oxidation rate during exercise. More in, more out. Some minor differences were observed in perceptual responses.

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Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

tim.hodson Mon, 02/03/2025 - 12:30 January 29, 2025 Roche announced today that the Tina-quant Lipoprotein (a) Gen.2 More than 90% of the Lp(a) level is influenced by variations in the genes controlling the Lp(a) particle production, 2 in which lifestyle interventions such as diet and exercise have no significant impact.

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Physiology Friday #249: Does Carbohydrate Distribution and Quality Matter for Optimizing Training Adaptations?

Physiologically Speaking

On the other hand, high-GI foods might be a boon for exercisers who want a quick energy source or a fast way to refuel after training. Post-exercise carbs were exclusively low-GI foods. Eur J Nutr 64, 23 (2025). How’s this apply to athletes? Just use the coupon code BRADY30 at checkout. 1 Vlahoyiannis, A., Andreou, E.,