Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP383-AWP383, February 1, 2025. Background and purpose:Vascular dementia (VaD) is one of the most common causes of cognitive decline, primarily resulting from cerebrovascular damage.

Dementia 40

Dementia Stenosis Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP117-AWMP117, February 1, 2025. Endothelial dysfunction, a key mechanism in COVID-19 illness, is also a major risk factor for vascular dementia (VaD). Introduction:SARS-CoV-2 causes various neurological sequelae in COVID-19 survivors including fatigue and cognitive dysfunction.

COVID-19 40

COVID-19 Dementia Risk Factors Pulmonary 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP48-ATP48, February 1, 2025. Introduction:Vascular cognitive impairment and vascular dementia are diagnosed based on brain vascular changes related to strokes. Strokes were self-reported and we used mini-mental score test (MMSE) to asses for cognitive impairment at each visit.

Strokes 40

Strokes Stroke Education Diabetes 40

Stroke Journal

DECEMBER 9, 2024

Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. 95% CI, 2.536.9];P=0.001), 95% CI, 2.536.9];P=0.001),

Dementia 40

Dementia Outcomes Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP349-ATP349, February 1, 2025. Background:Inflammation, a key player in both acute and chronic cerebral ischemia, is activated in brain tissues by bilateral carotid stenosis (BCAS)- induced chronic cerebral hypoperfusion.

Dementia 40

Dementia Ischemia Stenosis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP13-AWMP13, February 1, 2025. Cardiogenic dementia has been suggested to characterize patients suffering from cognitive decline after heart disease.

Dementia 40

Dementia Myocardial Infarction Ischemia Cardiovascular Disease 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A83-A83, February 1, 2025. Introduction:The recent update (version 2.0) Lobar CMBs occurred in 326 (51%) patients, cSS occurred in 197 (31%), multispot WMH pattern occurred in 123 (19%), and severe centrum semiovale EPVS occurred in 156 (24%).

Hemorrhage 40

Hemorrhage Dementia Hypertension Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP31-ATP31, February 1, 2025. Diabetes increases the risk of Vascular Contributions to Cognitive Impairment&Dementia (VCID) and stroke further amplifies this effect. Sovateltide improved both recognition memory and working spatial memory after stroke.

Diabetes 40

Diabetes Dementia Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP357-ATP357, February 1, 2025. Background:Despite the effectiveness of immediate treatment, such as thrombolytic therapy, after a stroke, many patients are unable to benefit due to time restrictions.

Ischemia 40

Ischemia Dementia Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP44-AWP44, February 1, 2025. Background:Patent foramen ovale (PFO) is an independent risk factor for neurovascular injury such as stroke. We previously found that large PFO shunt is associated with increased long-term risk of vascular dementia.

Dementia 40

Dementia Risk Factors Echocardiogram Circulation 40

Physiologically Speaking

FEBRUARY 14, 2025

They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days. 2025 Feb;35(2):e70024. Scand J Med Sci Sports.

Physiology 85

Physiology Exercise Research Dementia 85

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP248-ATP248, February 1, 2025. Objective:Silent brain infarctions (SBIs), which appear as dot-like lesions on diffusion-weighted imaging (DWI) after endovascular procedures, are associated with an increased risk of subsequent stroke, dementia and cognitive decline.

Angioplasty 40

Angioplasty Stents Stent Stenosis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP119-ATMP119, February 1, 2025. Background:Vascular cognitive impairment (VCI) is the second most frequent subtype of dementia following Alzheimer's disease. MicroRNAs (miRNAs) play critical roles in the pathologies of cerebral ischemia and dementia.

Dementia 40

Dementia Cholesterol Ischemia Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP215-ATP215, February 1, 2025. Background:Carotid stenosis has been associated with stroke and cognitive impairment. It remains unclear if hypometablism, a marker for neurodegeneration, may be in the mechanistic pathway in the association between carotid stenosis and cognitive decline.

Stenosis 40

Stenosis Dementia Ultrasound Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP22-ADP22, February 1, 2025. Introduction:Covert brain infarcts (CBIs) are associated with risk of stroke and dementia. Methods:Inclusion criteria were age > 40 years, no prior stroke or TIA, and available MRI brain scan.

Risk Factors 40

Risk Factors Cardiovascular Disease Dementia Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP252-ATP252, February 1, 2025. Alzheimers Disease (AD) is the most common form of dementia and is characterized by progressive neurodegeneration and cognitive decline.

Dementia 40

Dementia Risk Factors Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP53-AWP53, February 1, 2025. Cerebral white matter hyperintensities (WMH) on magnetic resonance imaging are part of the spectrum of brain vascular injury accompanying aging and are associated with an increased risk of stroke and dementia.

Dementia 40

Dementia Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP229-ATP229, February 1, 2025. Frequently, carotid artery stenosis is found during stroke workup and these patients undergo revascularization during the same nonelective admission.

Stents 40

Stents Stent Lipid disorders Heart Failure 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP14-ADP14, February 1, 2025. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive. Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis.

Diet 40

Diet Dementia Atherosclerosis Cholesterol 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP391-AWP391, February 1, 2025. Cerebral small vessel disease (SVD) contributes to approximately 50% of human dementias world-wide and pose a burden to the health care system worldwide. The current study evaluated multi-doses of SEW2871 as a novel therapy by targeting BBB damage for SVD.

Dementia 40

Dementia Diet Hypertension Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. In pre-specified sensitivity analyses, patients with a diagnosis of dementia at baseline were excluded.Results:Among 8.5 Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. years (IQR, 1.0-3.9),

Hemorrhage 40

Hemorrhage Cerebrovascular Disease Dementia Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP386-ATP386, February 1, 2025. Background:Aging increases risk for the development of vascular cognitive impairment and dementia (VCID).

Dementia 40

Dementia Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP15-ADP15, February 1, 2025. Background:White matter hyperintensities (WMH) of presumed vascular origin can be associated with vascular cognitive impairment and dementia. However, WMH are also seen in asymptomatic subjects.

Cerebrovascular Disease 40

Cerebrovascular Disease Dementia Risk Factors Cardiovascular Disease 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP33-ATP33, February 1, 2025. (1) 1) Background:Cerebral microbleeds (MBs) and cortical superficial siderosis (cSS) can be seen in a multitude of etiologies. The risk factors for cerebral MB and cSS and their relationship with cognitive decline are not well known.(2)

Risk Factors 40

Risk Factors Hypertension Dementia Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP319-AWP319, February 1, 2025. Introduction:Stroke and dementia are among the leading causes of mortality globally. This can be mitigated through targeting modifiable risk factors.

Risk Factors 40

Risk Factors Dementia Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP358-ATP358, February 1, 2025. Introduction:Stroke is a well-established independent risk factor for the development of dementia. Most dementia patients exhibit mixed brain pathologies, with histological evidence of ischemia and A plaque accumulation, observed at autopsy.

Dementia 40

Dementia Strokes Stroke Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2025. Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. Compared to individuals with no CMBs, presence of any CMBs was associated with an increased risk of dementia (Table 2).

Dementia 40

Dementia Certification Atherosclerosis Risk Factors 40

Stroke Journal

DECEMBER 5, 2024

Stroke, Volume 56, Issue 1 , Page 65-73, January 1, 2025. BACKGROUND:Socioeconomic disparities exist in acute stroke care as well as in long-term stroke outcomes. We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This 1000 person-years).

Dementia 40

Dementia Education Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP13-ADP13, February 1, 2025. Background:People with stroke are at high risk of dementia. Using linked administrative databases, we identified all 90-day dementia-free survivors of first acute ischemic stroke or intracerebral hemorrhage (ICH).

Dementia 40

Dementia Strokes Stroke Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP12-ADP12, February 1, 2025. Introduction:Stroke, dementia, and late-life depression (LLD) are age-related brain diseases that pose significant public health challenges. The Cox model confirmed these findings: stroke HRs for intermediate and longest LTL tertiles were 0.89 (95%CI: 0.85-0.94)

Dementia 40

Dementia Public Health Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP49-AWP49, February 1, 2025. This study investigates plasma pTau217 as a biomarker for distinguishing cognitive impairment and dementia in a cohort de-enriched for AD but enriched for vascular disease, focusing on its relationship with cognitive status and Fazekas scores.

Dementia 40

Dementia Biomarkers Education Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP50-AWMP50, February 1, 2025. Yet, little is known about the prevalence of health-related social risks (social risks) among stroke survivors. Stroke survivors were more likely to report social risks compared to older adults without a history of stroke (54.3%

Strokes 40

Strokes Stroke Dementia Education 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP57-AWP57, February 1, 2025. Introduction:Atrial fibrillation (AF) has been linked to cognitive impairment and dementia (CID) even among patients without clinically obvious stroke, but the mechanism is not established.

Atrial Fibrillation 40

Atrial Fibrillation Embolism Dementia Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP63-AWP63, February 1, 2025. Introduction:Visual impairments occur frequently in patients with cerebrovascular disease, particularly with carotid artery disease, which contributes to the development of vascular contributions to cognitive impairment and dementias (VCID).

Stenosis 40

Stenosis Dementia Cerebrovascular Disease Circulation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP45-AWP45, February 1, 2025. They are key indicators of cerebral small vessel disease (CSVD) and are associated with mild cognitive impairment (MCI) and dementia. Introduction:Perivascular Spaces (PVS) visible on brain MRI are fluid-filled compartments surrounding cerebral blood vessels.

Dementia 40

Dementia Biomarkers Education Diabetes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP42-ATP42, February 1, 2025. Importantly, patients with CCH show enhanced brain iron deposition and iron metabolism dysregulation, which have been associated with different types of dementia and neurodegenerative disorders, such as Alzheimers disease, Huntingtons disease, VCID, etc.

Dementia 40

Dementia Stenosis Risk Factors Strokes 40

Stroke Journal

DECEMBER 5, 2024

Stroke, Volume 56, Issue 1 , Page 95-104, January 1, 2025. Participants underwent brain magnetic resonance imaging scans every 3 to 4 years between 2005 and 2016.

Blood Pressure 40

Blood Pressure Dementia Cardiovascular Disease Diabetes 40