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The Best Way To Prevent Dementia

Dr. Paddy Barrett

More than heart disease or cancer, dementia is the primary concern for many of the patients I see. Heart disease and cancer attack your body, but dementia attacks your mind and identity. That is why I believe people fear dementia so much. Thankfully, 45% of all dementia is preventable 1. That factor is exercise.

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Abstract WP51: Non-Traumatic Intracranial Hemorrhage and Risk of Incident Dementia

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The outcome was an incident diagnosis of dementia. In the primary analysis, we used Cox regression to study the risk of dementia after any intracranial hemorrhage, after adjusting for demographics and comorbidities. During a median follow up of 5.6

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Abstract WP269: Predicting post-stroke all-cause dementia incidence using machine learning models and electronic health record data

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP269-AWP269, February 1, 2025. Introduction:All-cause dementia remains a significant public health concern, with stroke recognized as a key risk factor. The primary outcome was the incidence of all-cause dementia within one year post-stroke. Among those who developed dementia, 49.7%

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Letter by Wei and Yu Regarding Article, “Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities)”

Circulation

Circulation, Volume 151, Issue 12 , Page e764-e764, March 25, 2025.

Article 49
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Response by Zhao et al to Letters Regarding Article, “Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities)”

Circulation

Circulation, Volume 151, Issue 12 , Page e766-e766, March 25, 2025.

Article 49
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Abstract WP400: SARS-CoV-2 Spike Protein Accelerates Alzheimer’s Disease-Related Dementia Through Increased Cerebrovascular Inflammation in hACE2 Mice

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP400-AWP400, February 1, 2025. SARS-COV-2 causes neurological and cognitive impairments and aggravates Alzheimers Disease-Related Dementia (ADRD). Yet, the molecular mechanism is not fully understood.

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Abstract WP346: Pharmacological Inhibition of Transforming Growth Factor Beta Receptor Improves Breathing Function and Cognition in Mice Models of Dementia

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP346-AWP346, February 1, 2025. Dementia is associated with respiratory dysfunction. In mice models of dementia, there is increased astrogliosis in the brain stem retro-trapezoid nucleus (RTN), which is crucial for breathing control.