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Circulation, Ahead of Print. The 2025 AHA Statistical Update is the product of a full years worth of effort in 2024 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members.
The 2025 American Heart Association statistics were published recently, and heart disease remains the leading cause of death in the US and globally 1. The Consequences of High Cholesterol Why high cholesterol is more than just a number—it’s a major risk factor for heart disease and stroke. Circulation. 2025 Jan 27.
Stroke, Volume 56, Issue Suppl_1 , Page AWP167-AWP167, February 1, 2025. Background:Small studies have found that patients presenting with posterior circulation ischemic strokes are more likely than patients with anterior circulationstrokes to suffer a missed or delayed diagnosis in the ED.
tim.hodson Mon, 03/17/2025 - 14:56 March 17, 2025 Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Associations flagship journal Circulation. are forms of congenital heart defects (CHD). In the U.S.,
tim.hodson Mon, 03/31/2025 - 10:26 March 31, 2025 AGEPHA Pharma USA, LLC, has released clinical data that provides new information about how low-dose colchicine, 0.5 mg can prevent heart attack and stroke in high-risk patients with established cardiovascular disease. These new data reinforce the use of LODOCO(colchicine, 0.5
Stroke, Volume 56, Issue Suppl_1 , Page ATMP82-ATMP82, February 1, 2025. Introduction:Aspiration and stent retriever thrombectomy are the primary approaches for endovascular management of posterior circulationstroke. However, the optimal first-line choice of surgical technique remains unclear.
Heart disease and stroke remained the leading causes of death in the U.S. in 2022, outpacing the number of combined deaths from cancer and accidental deaths, according to the American Heart Associations 2025 Heart Disease and Stroke Statistics report, published Jan. 27 in Circulation.
Stroke, Volume 56, Issue Suppl_1 , Page AWP354-AWP354, February 1, 2025. Background:Circulating neuroinflammatory factors change rapidly in acute stroke, but the association with ischemic lesion size and stroke severity is unknown. Twenty-six (57%) MSU patients were confirmed ischemic stroke (AIS). range 0-171) mL.
Stroke, Volume 56, Issue Suppl_1 , Page ATP307-ATP307, February 1, 2025. Results:A total of 20 peripheral blood PBMC samples were collected from patients with acute ischemic stroke before and after the occurrence of END.
Stroke, Volume 56, Issue Suppl_1 , Page AWP88-AWP88, February 1, 2025. Background:The effect of renal dysfunction on early infarct growth rate (IGR) in anterior circulation large vessel occlusion (ACLVO) stroke is not well studied. mg/dL, p < 0.05) and lower median eGFR (66.2 mL/min/1.73m2, p < 0.05).
Stroke, Volume 56, Issue Suppl_1 , Page A13-A13, February 1, 2025. We included patients with acute ischemic stroke due to PCTLs who were treated with EVT. The patients were divided into two groups based on whether they received adjunctive intravenous Tirofiban therapy or not. 4.03], P=0.19). 0.59], P=0.001).Conclusion:Intravenous
tim.hodson Mon, 03/31/2025 - 15:02 March 31, 2025 iRhythm Technologies, Inc. has announced results from two large real-world retrospective analyses presented at the American College of Cardiology (ACC) 2025 Scientific Sessions in Chicago. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study.
Stroke, Volume 56, Issue Suppl_1 , Page A70-A70, February 1, 2025. Purpose:Fast progressors (FP) of infarct growth in anterior circulation occlusions at 0-6 hours from onset (early window) have been associated with reduced rates of favorable outcome post endovascular thrombectomy (EVT).
Stroke, Volume 56, Issue Suppl_1 , Page AWP306-AWP306, February 1, 2025. variants in the vicinity (300 kb) of theADIPOQgene from a GWAS of circulating adiponectin levels (n=~38,600). 0.98; p=0.006) risk, but not ischemic stroke/subtypes (all p-values > 0.05). We selected genome-wide, independent (r2<0.1)
Stroke, Volume 56, Issue Suppl_1 , Page AWP67-AWP67, February 1, 2025. Introduction:Senescent cells accumulate with advancing age, and exposure to cellular stressors, such as oxidative and inflammatory molecules, which can be circulating in blood.
Stroke, Volume 56, Issue Suppl_1 , Page ATP140-ATP140, February 1, 2025. Moreover, it is unclear what effective therapeutic targets as well as molecular systemic changes in stroke in the chronic phase. Moreover, it is unclear what effective therapeutic targets as well as molecular systemic changes in stroke in the chronic phase.
Stroke, Volume 56, Issue Suppl_1 , Page ATP296-ATP296, February 1, 2025. Introduction:Nonstenotic carotid plaque is found in some patients with otherwise cryptogenic stroke (CS) but also in normal individuals and patients with stroke of known cause (KS).
Stroke, Volume 56, Issue Suppl_1 , Page ATMP49-ATMP49, February 1, 2025. Background and Objective:A stable perfusion pattern may guarantee a good clinical outcome in acute stroke patients. Recanalization status was evaluated through follow-up perfusion or angiography imaging. 95% CI: 2.9 - 26.4, 95% CI: 1.1 - 83.8,
Stroke, Volume 56, Issue Suppl_1 , Page AWP244-AWP244, February 1, 2025. Introduction:Stroke is a leading cause of global mortality and morbidity, affecting approximately 15 million people annually, with ischemic stroke accounting for 85% of cases. Changes were present over the ipsilateral and contralateral hemispheres.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP57-AWMP57, February 1, 2025. Background:The vascular region of a stroke is reported in International Classification of Diseases-10 (ICD10) subcodes as either a specific or nonspecific/unspecified location. The overall accuracy has implications for research.
Stroke, Volume 56, Issue Suppl_1 , Page ATP265-ATP265, February 1, 2025. Objective:Strokeheart syndrome (SHS) leads to poorer prognosis in patients with acute ischemic stroke (AIS), which makes early identification and prevention of SHS crucial.
Stroke, Volume 56, Issue Suppl_1 , Page ATP361-ATP361, February 1, 2025. Introduction:Stroke is a leading cause of death and disability worldwide, with diabetes being a significant risk factor that exacerbates stroke outcomes. The CellChat tool was employed to analyze the intercellular communication between these cells.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP59-ATMP59, February 1, 2025. A neurologist assessed ischemic stroke based on medical records, and a neuroradiologist established the ground truth using the neurologist's evaluation, MRI reports, and AI-marked DWI images. mL in the anterior circulation. mL vs. 99.5%
Stroke, Volume 56, Issue Suppl_1 , Page ANS3-ANS3, February 1, 2025. Background and Purpose:Prehospital recognition of stroke directly contributes to the reduction of mortality for stroke patients. Furthermore, inaccurate last known well times (LKWT) can delay emergent stroke care. pre-class score was 3.7,
Stroke, Volume 56, Issue Suppl_1 , Page ATP196-ATP196, February 1, 2025. Stroke, especially in the aged population, affects the lung health of stroke patients, and this influences the stroke outcome. Blood circulating CC-motif chemokine 11 (CCL11) increases in rodents and humans with age.
Stroke, Volume 56, Issue Suppl_1 , Page A91-A91, February 1, 2025. The acute phase of ischemic stroke triggers a complex cascade of cellular responses in the brain and the immune system. However, little is known about cellular lipid alterations in peripheral immunity acutely after stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP57-ATMP57, February 1, 2025. Introduction:Literature demonstrates that nearly one-third of acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) or severe stenosis arrive at the emergency room with mild symptoms, attributed to favourable collateral status.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP26-AWMP26, February 1, 2025. Introduction:Several pre-hospital scales predict ischemic stroke due to large vessel occlusion; however, these scales often fail to detect atypical endovascular thrombectomy (EVT) cases, including posterior circulation and distal vessel occlusion.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP96-ATMP96, February 1, 2025. Introduction:Pediatric arterial ischemic stroke (AIS) affects 1-2 per 100,000 children. Although rare, mortality and morbidity is significant with approximately 10% recurrence rate within the first year.
Stroke, Volume 56, Issue Suppl_1 , Page ATP341-ATP341, February 1, 2025. Introduction:Peripheral blood-based biomarker development for neurological diseases such as ischemic stroke has traditionally focused on measuring alterations in leukocyte number and composition. This difference was more pronounced among females.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP58-ATMP58, February 1, 2025. Baseline demographics and National Institutes of Health Stroke Scale (NIHSS) were similar between groups. However, in hyperacute ischemic infarcts, diffusion-weighted imaging (DWI) hyperintense lesions can show varying ADC values. P < 0.0001).
Stroke, Volume 56, Issue Suppl_1 , Page AWP253-AWP253, February 1, 2025. Background and Aims:Endovascular treatment (EVT) alone has been confirmed to be non-inferior to intravenous thrombolysis (IVT) followed with EVT in acute ischemic stroke (AIS) due to large-vessel occlusion of the anterior circulation.
Stroke, Volume 56, Issue Suppl_1 , Page ADP38-ADP38, February 1, 2025. Background:Endovascular therapy (EVT) has emerged as a first-line intervention for vertebrobasilar artery occlusion (VBAO) patients, supported by two recent landmark randomized controlled trials.
Stroke, Volume 56, Issue Suppl_1 , Page ATP87-ATP87, February 1, 2025. Background:Early prediction of functional outcome after rtPA helps clinicians in prognostic conversations with stroke patients and their families. 12% of the cohort (n=34) had posterior circulationstroke. Of those, 43% (n=119) were male.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP11-AWMP11, February 1, 2025. Background:Endovascular thrombectomy (EVT) has improved both short-term and long-term outcomes for acute ischemic stroke (AIS) patients caused by large vessel occlusion (LVO). Methods:This was a retrospective, single-center observational study.
Stroke, Volume 56, Issue Suppl_1 , Page A57-A57, February 1, 2025. Background:Acute ischemic stroke is a leading cause of death and disability in the U.S. Patients with an initial Alberta Stroke Program Early CT Score (ASPECTS)>6 were compared to those with ASPECTS < 6.
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