2025 and BMI - Cardiovascular Update

Cardiovascular Fitness: The Key to Longevity | Golden Age Health Summit 2025

Physiologically Speaking

MARCH 30, 2025

I delivered it at the Golden Age Health Summit on March 15, 2025, in Austin, TX. Learn how VO2 max integrates multiple physiological systems (lungs, heart, blood vessels, mitochondria, and more) and why it’s a stronger predictor of longevity than traditional risk factors like cholesterol or BMI.

Physiology

Physiology BMI Cholesterol Risk Factors

Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

DAIC

MARCH 31, 2025

tim.hodson Mon, 03/31/2025 - 16:38 March 29, 2025 Anthos Therapeutics, Inc., In addition, abelacimab consistently reduced bleeding risk in patients 75 years of age and older regardless of renal function, body mass index (BMI), and the use of concomitant antiplatelet therapy. The ARR in patients 75 years of age and older was 6.2%

Atrial Fibrillation

Atrial Fibrillation BMI General Cardiology Thrombosis

Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

DAIC

JANUARY 8, 2025

tim.hodson Wed, 01/08/2025 - 14:11 Jan. 8, 2025 Mineralys Therapeutics, Inc., The Company anticipates initiating the trial in the first quarter of 2025. Subjects will be at least 18 years old, with a BMI 27 kg/m 2 , and the trial will be conducted across approximately 40 sites.

Blood Pressure

Blood Pressure Hypertension Kidney Disease BMI

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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GE Healthcare Launches New Cardiac PET tracer

DAIC

MARCH 27, 2025

tim.hodson Thu, 03/27/2025 - 15:40 March 27, 2025 GE HealthCare is announcing theU.S.launch of Flyrcado(flurpiridaz F 18) injection at the 2025American College of Cardiology(ACC) AnnualScientific Session & Expo inChicago. Flyrcado is aunit dose positron emission tomography myocardial perfusion imaging (PET MPI) agent.

Coronary Artery Disease

Coronary Artery Disease CMS Innovation Ischemia

Physiology Friday #254: Fueling for Performance and Health: Lessons from a Recent Low-Carb vs. High-Carb Study in Athletes

Physiologically Speaking

JANUARY 24, 2025

Participants on the low-carb diet experienced significant reductions in body weight, BMI, and body fat percentage compared to those on the high-carb diet. kg/m² reduction in BMI, and decreased their body fat percentage by 1.9%. 2025 Jan 9. Over the six weeks, the low-carb group lost an average of 2.3 doi: 10.1152/ajpcell.00583.2024.

Physiology

Physiology Diet Exercise BMI

Abstract WMP12: Heterogeneous Treatment Effects of Colchicine in patients with acute ischaemic stroke or transient ischaemic attack

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP12-AWMP12, February 1, 2025. Based on causal forest models, mean corpusular volume, triglyceride, BMI, and the neutrophil count distinguished patients who differentially benefited from colchicine (interaction p =0.02). mmol/L, BMI higher than 23.39 g/L, triglyceride higher than 1.39

Strokes

Strokes Stroke BMI Outcomes

Abstract WP294: Racial Disparities among the risk of Stroke and other clinical outcomes post Infective Endocarditis: A Propensity Matched Analysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP294-AWP294, February 1, 2025. Propensity score-matched analysis (PSM) (1:1) was performed on age, gender, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, LDL level, left ventricular ejection fraction and various drugs including beta blockers, ACEi and ARBi.

Cardiogenic Shock

Cardiogenic Shock Strokes Stroke Outcomes

Abstract WP269: Predicting post-stroke all-cause dementia incidence using machine learning models and electronic health record data

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP269-AWP269, February 1, 2025. They had slightly higher systolic blood pressure, lower BMI, higher rates of comorbidities, and medication use (Table 1). Introduction:All-cause dementia remains a significant public health concern, with stroke recognized as a key risk factor. The sample was 48.4%

Dementia

Dementia Strokes Stroke Blood Pressure

Abstract WP203: Ipsilateral Hemodynamic Failure of Extracranial Internal Carotid Artery is Associated with Severe Middle Cerebral Artery Atherosclerosis——a 4D Flow MRI Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. After adjusting for age, gender, BMI and traditional risk factors, low flow (both the flowavgand flowmaxwere less than the mean value of all patients' C1ips) was independently associated with ipsilateral MCA severe stenosis or occlusion (OR,7.65[95%CI

Atherosclerosis

Atherosclerosis Stenosis Risk Factors BMI

Abstract DP42: A Stroke Case Management Program To Improve Hospital Readmission Rates After Index Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP42-ADP42, February 1, 2025. Introduction:The transitional period from hospital discharge to the community for stroke survivors is a vulnerable time as patients navigate healthcare systems with their new impairments.

Hospital

Hospital Strokes Stroke Nursing

Abstract TP268: Xylitol, Xylose, and MicroRNAs Associated with Thrombosis and the Clotting Cascade in a Multi-Omics Cross-Sectional Study of Adults at Risk for Type 2 Diabetes and Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. The mean BMI was 35.2 Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack. kg/m2, HbA1c was 5.9% 0.4,

Thrombosis

Thrombosis Obesity Strokes Stroke

Abstract 52: Glucagon-like peptide-1 receptor agonists use and outcomes in Cardiac Amyloidosis patients: A Propensity Matched Analysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A52-A52, February 1, 2025. Patients were categorized into two groups, one with cardiac amyloidosis on GLP-1 RA and a control group with cardiac amyloidosis without GLP-1 RA. Patients were assessed at follow-up periods of 1 month and 1 year.

Outcomes

Outcomes Atrial Fibrillation Heart Failure Tachycardia

Abstract TMP42: Enhancing Stroke Rehabilitation: A Quality Improvement Initiative

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP42-ATMP42, February 1, 2025. Patients with higher BMIs were not likely to meet their mobility goal. BMI and AMS were independent predictors of whether people met their mobility goal. The American Stroke Association cites strokes as the fifth leading cause of death in the United States.

Strokes

Strokes Stroke Medicare BMI

Abstract WP319: Reliability and validity of self-reported risk factors for stroke and dementia

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP319-AWP319, February 1, 2025. Introduction:Stroke and dementia are among the leading causes of mortality globally. This can be mitigated through targeting modifiable risk factors.

Risk Factors

Risk Factors Dementia Strokes Stroke

Abstract WP388: Plasma Eicosanoids Are Associated with Incident Stroke Over Decades in Participants in the Atherosclerosis Risk in Communities (ARIC) Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP388-AWP388, February 1, 2025. Introduction:Eicosanoids (EIC) are lipid mediators that play a systemic role in inflammation and, more specifically, in the brain, contribute to the process of neurovascular coupling. Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2%

Atherosclerosis

Atherosclerosis Strokes Stroke Atrial Fibrillation

Abstract TP186: Patients with Acute Ischemic Stroke in the United States Exhibit more Dependency 90 Days after Stroke than those in a Matched Norwegian Cohort

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP186-ATP186, February 1, 2025. The US cohort had greater ethno-racial heterogenity, higher BMI, and higher NIHSS on admission. Introduction:Acute ischemic stroke (AIS) imposes a disparate burden across global populations. A greater proportion of the US cohort underwent IV thrombolysis (30.7%

Strokes

Strokes Stroke Thrombolysis Atrial Fibrillation

Abstract TP378: Malondialdehyde as a Clinical Indicator for Oxidative Stress: Associations with Age, BMI, and Cognitive Impairment

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP378-ATP378, February 1, 2025. Introduction:The molecular and metabolic changes that occur after acute ischemic stroke (AIS) are not fully understood.

BMI

BMI Biomarkers Dementia Strokes

Abstract WP314: Trends in adherence to secondary prevention guidelines after stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP314-AWP314, February 1, 2025. These involve managing and controlling risk factors for recurrence, such as blood pressure, body mass index (BMI), low-density lipoprotein (LDL) cholesterol, glycated hemoglobin (HbA1c), smoking, alcohol consumption and physical activity.

Blood Pressure

Blood Pressure Strokes Stroke BMI

Cardiovascular Fitness: The Key to Longevity | Golden Age Health Summit 2025

Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

Mineralys Therapeutics Announces Phase 2 Clinical Trial of Lorundrostat

Webinars

GE Healthcare Launches New Cardiac PET tracer

Physiology Friday #254: Fueling for Performance and Health: Lessons from a Recent Low-Carb vs. High-Carb Study in Athletes

Abstract WMP12: Heterogeneous Treatment Effects of Colchicine in patients with acute ischaemic stroke or transient ischaemic attack

Abstract WP294: Racial Disparities among the risk of Stroke and other clinical outcomes post Infective Endocarditis: A Propensity Matched Analysis

Abstract WP269: Predicting post-stroke all-cause dementia incidence using machine learning models and electronic health record data

Abstract WP203: Ipsilateral Hemodynamic Failure of Extracranial Internal Carotid Artery is Associated with Severe Middle Cerebral Artery Atherosclerosis——a 4D Flow MRI Study

Abstract DP42: A Stroke Case Management Program To Improve Hospital Readmission Rates After Index Stroke

Abstract TP268: Xylitol, Xylose, and MicroRNAs Associated with Thrombosis and the Clotting Cascade in a Multi-Omics Cross-Sectional Study of Adults at Risk for Type 2 Diabetes and Stroke

Abstract 52: Glucagon-like peptide-1 receptor agonists use and outcomes in Cardiac Amyloidosis patients: A Propensity Matched Analysis

Abstract TMP42: Enhancing Stroke Rehabilitation: A Quality Improvement Initiative

Abstract WP319: Reliability and validity of self-reported risk factors for stroke and dementia

Abstract WP388: Plasma Eicosanoids Are Associated with Incident Stroke Over Decades in Participants in the Atherosclerosis Risk in Communities (ARIC) Study

Abstract TP186: Patients with Acute Ischemic Stroke in the United States Exhibit more Dependency 90 Days after Stroke than those in a Matched Norwegian Cohort

Abstract TP378: Malondialdehyde as a Clinical Indicator for Oxidative Stress: Associations with Age, BMI, and Cognitive Impairment

Abstract WP314: Trends in adherence to secondary prevention guidelines after stroke

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