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Photo: American Heart Association tim.hodson Tue, 01/14/2025 - 16:05 Jan. 9, 2025 Gender-based racism through microaggressions may be linked to higher bloodpressure postpartum and beyond, according to new research published in Hypertension , a peer-reviewed journal of the American Heart Association. mm Hg and 1.43
The 2025 AHA Statistical Update is the product of a full years worth of effort in 2024 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members.
tim.hodson Mon, 03/10/2025 - 11:17 At the Cardiovascular Research Technologies (CRT) 2025 conference in Washington, D.C., The analysis of data from SCAARon the Prevail coronary paclitaxel drug-coated balloon (DCB) will be presented as a late-breaking clinical trial at Cardiovascular Research Technologies (CRT) 2025 in Washington, D.C.
tim.hodson Wed, 01/08/2025 - 14:11 Jan. 8, 2025 Mineralys Therapeutics, Inc., The Company anticipates initiating the trial in the first quarter of 2025. We believe suppression of aldosterone production by lorundrostat has the potential to reduce the nocturnal hypertension driving adverse cardiovascular outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page A119-A119, February 1, 2025. Background:The deleterious effects of intensive bloodpressure (BP) lowering in patients who achieved successful reperfusion may result from high BP variability (BPV). TR fully mediated the association between intensive BP management and functional outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page ADP17-ADP17, February 1, 2025. Introduction:Following a large vessel occlusion acute ischemic stroke (LVO-AIS), cerebral autoregulation is notably compromised, making cerebral blood flow maintenance and optimal bloodpressure (BP) crucial to preserving the penumbral tissue until reperfusion.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP18-ATMP18, February 1, 2025. Background and Issues:Timely identification and intervention are critical for positive outcomes in acute intracerebral hemorrhage (ICH) patients. Conclusions:Having measurable goals for ICH has demonstrated a significant improvement in outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page ATP223-ATP223, February 1, 2025. The ePWV was calculated using a regression equation based on age and mean bloodpressure at trial enrollment. The primary outcome was functional independence at 3 months, defined as a modified Rankin Scale (mRS) score of 0-2.
tim.hodson Mon, 03/10/2025 - 11:17 At the Cardiovascular Research Technologies (CRT) 2025 conference in Washington, D.C., The analysis of data from SCAARon the Prevail coronary paclitaxel drug-coated balloon (DCB) will be presented as a late-breaking clinical trial at Cardiovascular Research Technologies (CRT) 2025 in Washington, D.C.
Stroke, Volume 56, Issue Suppl_1 , Page AWP290-AWP290, February 1, 2025. Introduction:Prior research has suggested that psychiatric disease, particularly bipolar disorder, may increase the risk of cardiovascular events and stroke.Methods:We performed a post-hoc analysis of the Systolic BloodPressure Intervention Trial (SPRINT).
Stroke, Volume 56, Issue Suppl_1 , Page AWP368-AWP368, February 1, 2025. In this study, we evaluated the effect of MnP-05 on short-term outcomes of SAH in mice.Methods:We used 12-week-old male C57BL/6J mice. There were no differences in bloodpressure or body weight between the two groups. P<0.05, Fig.
Stroke, Volume 56, Issue Suppl_1 , Page AWP6-AWP6, February 1, 2025. Background and Purpose:Whether imaging markers of cerebral small vessel disease on computed tomography (CT-CSVD) relates to early clinical outcomes after intravenous thrombolysis for acute ischemic stroke remains not well understood. 1.02; score 2: OR 0.46, 95%CI 0.26-0.83;
Stroke, Volume 56, Issue Suppl_1 , Page A63-A63, February 1, 2025. Cholesterol control, blood sugar management, tobacco cessation, and bloodpressure management were chosen using the American Heart Associations Lifes Crucial 9 for their Medicare coding availability. Improvements in functional outcomes were greater.
Hypertension, Volume 82, Issue 1 , Page 106-117, January 1, 2025. BACKGROUND:Neurogenic orthostatic hypotension (nOH) causes pathological falls in standing bloodpressure that may or may not be symptomatic. Recognizing the clinical implications of CBFv in nOH is crucial for mitigating adverse outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP5-AWMP5, February 1, 2025. Several methods have been described to derive NNT for ordinal outcomes. Overall, the magnitude of treatment effect estimates rendered by Permutation methods were substantially lower than by Joint Outcome methods Table methods.
Stroke, Volume 56, Issue Suppl_1 , Page ATP21-ATP21, February 1, 2025. IntroductionThe efficacy of bloodpressure (BP) reduction of Sacubitril/valsartan has been proved in hypertension patients, yet not in patients with acute ischemic stroke (AIS). hours and 57.014.8 hours, respectively.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP11-AWMP11, February 1, 2025. Background:Endovascular thrombectomy (EVT) has improved both short-term and long-term outcomes for acute ischemic stroke (AIS) patients caused by large vessel occlusion (LVO). Methods:This was a retrospective, single-center observational study.
Stroke, Volume 56, Issue Suppl_1 , Page AWP136-AWP136, February 1, 2025. ICH expansion causes worse outcomes, especially with anticoagulant-associated ICH. The checklist tracks bloodpressure (BP) management and calling a neurosurgery consult. Time to neurosurgical intervention did not show improvement post intervention.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP110-ATMP110, February 1, 2025. As a safety study, we measured the body weight and bloodpressure during the pretreatment. Future research should evaluate the long-term outcomes and the mechanisms by which microplastics and nanoplastics exacerbate the ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page AWP8-AWP8, February 1, 2025. There were no significant differences in age, presenting bloodpressure, or NIHSS between the two groups. The mean length of ICU-stay for the HIM group was 32.8 No patient in the TIM pathway required transfer to the ICU for a higher level of care.
Stroke, Volume 56, Issue Suppl_1 , Page ATP39-ATP39, February 1, 2025. RIC consisted of 4 cycles of blood-pressure cuff inflation to 200mmHg around an arm for 5-minutes followed by 5-minutes deflation using an automated device. Outcomes were assessed at 30- and 90-days. 21/22(95.5%) finished the 30-day treatment period.
Stroke, Volume 56, Issue Suppl_1 , Page AWP269-AWP269, February 1, 2025. The primary outcome was the incidence of all-cause dementia within one year post-stroke. They had slightly higher systolic bloodpressure, lower BMI, higher rates of comorbidities, and medication use (Table 1). The sample was 48.4% aged 20-44, 37.2%
Stroke, Volume 56, Issue Suppl_1 , Page ADP49-ADP49, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is associated with poor outcomes in part due to a lack of perceived sense of urgency.
Stroke, Volume 56, Issue Suppl_1 , Page AWP124-AWP124, February 1, 2025. Ventricular lateral atrophy was observed (BF=4.105), and higher baseline bloodpressure and poorer collaterals were associated with larger long term lateral ventricular atrophy (BF: 11, 11, 4.3 respectively).
Stroke, Volume 56, Issue Suppl_1 , Page ATP50-ATP50, February 1, 2025. The staff would retrieve the alteplase from the cabinet after the order was entered into the electronic medical record and then return to the cabinet to remove antihypertensives to treat the patients bloodpressure before the alteplase administration.
Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025. We calculated the polygenic profile (PP) by combining five standardized polygenic risk scores for systolic bloodpressure, type 2 diabetes, low- and high-density lipoproteins, and glomerular filtration rate, along withAPOEepsilon 4 and 2 genotypes.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP2-AWMP2, February 1, 2025. In addition, neuroprotective measures have influenced outcomes in mortality, morbidity, and disability. The treatment strategy for acute ischemic stroke (AIS) is reperfusion.
Stroke, Volume 56, Issue Suppl_1 , Page A70-A70, February 1, 2025. Purpose:Fast progressors (FP) of infarct growth in anterior circulation occlusions at 0-6 hours from onset (early window) have been associated with reduced rates of favorable outcome post endovascular thrombectomy (EVT).
tim.hodson Tue, 02/04/2025 - 17:13 Feb. 3, 2025 Today, Peripheral Artery Disease (PAD)affects 10 million Americans and is the most common cause of limb amputation outside of trauma. If you have a history of diabetes, high bloodpressure, or tobacco use, you should talk to your doctor about being screened for PAD.
tim.hodson Tue, 03/25/2025 - 16:19 March 25, 2025 Bayer plans to present data from 13 new analyses from across the KERENDIA (finerenone) comprehensive clinical trial program at the American College of Cardiology (ACC) 74 th Annual Scientific Session & Expo 2025 , in Chicago, IL, March 29-31, 2025. Additional ACC.25
Stroke, Volume 56, Issue Suppl_1 , Page ATP264-ATP264, February 1, 2025. Bloodpressure is an important modifiable factor associated with poor neurological outcomes. We reviewed data on demographics, clinical outcome, radiologic, hemodynamic parameters, and medication. years and range 17 years) were included.
Stroke, Volume 56, Issue Suppl_1 , Page ATP263-ATP263, February 1, 2025. Bloodpressure is an important modifiable factor associated with poor neurological outcomes. We reviewed data on demographics, clinical outcome, radiologic, hemodynamic signs, and medication within PICU.
Stroke, Volume 56, Issue Suppl_1 , Page AWP7-AWP7, February 1, 2025. Introduction:Blood pressure is a simple physiologic parameter that is always measured, can be modulated, and may affect the outcome.
At the 77th World Health Assembly ( WHA ) during an event co-hosted with the Ministry of Health for Uganda , AstraZeneca announced that the expanded Healthy Heart Africa program will be operational in Côte d'Ivoire, Egypt, Ethiopia, Ghana, Kenya, Nigeria, Rwanda, Senegal and Uganda by the end of 2025.
Stroke, Volume 56, Issue Suppl_1 , Page A85-A85, February 1, 2025. Background:Systolic bloodpressure (SBP) fluctuation is linked to increased death or disability in intracerebral hemorrhage (ICH) patients. These findings suggest this time window is crucial for future interventions aimed at controlling SBP in ICH patients.
Stroke, Volume 56, Issue Suppl_1 , Page ATP34-ATP34, February 1, 2025. Background:Elevated bloodpressure variability (BPV) has been associated with worse outcomes in stroke survivors. The standard deviations of both systolic and diastolic bloodpressures were significant predictors of PSCI (aOR 1.09; 95% CI 1.011.17
Stroke, Volume 56, Issue Suppl_1 , Page ATMP62-ATMP62, February 1, 2025. Background:Elevated bloodpressure (BP) is common after Intracerebral Hemorrhage (ICH) and is linked with increased morbidity and mortality, partly due to hematoma expansion. The same was true for prehospital BP management in undifferentiated stroke.
Stroke, Volume 56, Issue Suppl_1 , Page AWP235-AWP235, February 1, 2025. Disparities in outcomes of patients with ischemic stroke have been associated with insurance coverage. However, there are few studies investigating the impact of insurance status on outcomes in patients with intracerebral hemorrhage (ICH).Methods:We
Stroke, Volume 56, Issue Suppl_1 , Page AWP234-AWP234, February 1, 2025. Introduction:Education, a key modifiable social determinant of health, plays a significant role in shaping outcomes related to ischemic stroke. The predicted probability of good outcome by education level was significantly different (Figure 1).
tim.hodson Tue, 03/25/2025 - 16:19 March 25, 2025 Bayer plans to present data from 13 new analyses from across t he KERENDIA (finerenone) comprehensive clinical trial program at the American College of Cardiology (ACC) 74 th Annual Scientific Session & Expo 2025 , in Chicago, IL, March 29-31, 2025. Additional ACC.25
Stroke, Volume 56, Issue Suppl_1 , Page ATP117-ATP117, February 1, 2025. Background:Uncontrolled high bloodpressure is a risk factor for acute stroke and a predictor of poor stroke outcomes.
Stroke, Volume 56, Issue Suppl_1 , Page AWP287-AWP287, February 1, 2025. Introduction:Effective bloodpressure (BP) control post-stroke is a critical secondary prevention strategy. The primary outcome was the reduction in systolic BP (RSBP) from baseline to the follow-up. years, with 52.6%
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