Stroke Journal

JANUARY 26, 2025

Stroke, Volume 56, Issue 2 , Page 475-477, February 1, 2025.

Stroke 40

Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP101-AWMP101, February 1, 2025. It remains unclear if the biomarkers used in the trial reliably identified atrial cardiopathy. It remains unclear if the biomarkers used in the trial reliably identified atrial cardiopathy. and Canada. and Canada.

Biomarkers 40

Biomarkers Cardiomyopathy Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP359-AWP359, February 1, 2025. Background:Mechanical thrombectomy has been associated with improved outcomes in patients with acute ischemic stroke. Investigating the post-reperfusion inflammatory milieu could provide valuable insights into the mechanisms that influence stroke outcomes.

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Biomarkers Stroke Strokes Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP1-ATMP1, February 1, 2025. A cerebral aneurysm (CA) is an abnormal artery deformation in the brain that may lead to hemorrhagic stroke, brain damage, coma, and even death when a CA ruptures. We hypothesized that increasing CA sample size will allow more robust biomarker identification.

Aneurysm 40

Aneurysm Biomarkers Cardiomyopathy Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP341-ATP341, February 1, 2025. Introduction:Peripheral blood-based biomarker development for neurological diseases such as ischemic stroke has traditionally focused on measuring alterations in leukocyte number and composition. This difference was more pronounced among females.

Biomarkers 40

Biomarkers Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP44-ATP44, February 1, 2025. However, no effective serum biomarker has been established for early diagnosis or prediction of the disease progression. However, no effective serum biomarker has been established for early diagnosis or prediction of the disease progression.

Biomarkers 40

Biomarkers Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP49-ATP49, February 1, 2025. Background:Small vessel cerebral vascular disease (sCVD) is common to older individuals, often asymptomatic, but associated with incident stroke and future mortality. years of education. Future work will associate these findings with sCVD phenotypes.

Biomarkers 40

Biomarkers Education Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2025. Early intervention has been shown to improve patient prognosis, highlighting the necessity of sensitive biomarkers. These biomarkers could facilitate timely interventions, potentially improving outcomes for stroke patients.

Biomarkers 40

Biomarkers Physiology Hemorrhage Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. Finally, as neutrophil counts (and the ratio of neutrophils to lymphocytes) are reported to be a biomarker for DCI, we assessed these measures too. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH).

Aneurysm 40

Aneurysm Biomarkers Ischemia Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP16-ADP16, February 1, 2025. Introduction:The National Institutes of Health Stroke Scale (NIHSS) provides a clinical measure of stroke severity. We collected blood from each patient at hospital admission before administering any therapeutic intervention.

Stroke 40

Stroke Strokes Biomarkers Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP377-ATP377, February 1, 2025. Timely and accurate risk stratification of IAs is paramount.Objective:Aneurysm wall enhancement (AWE) is a potential imaging biomarker for risk stratification.

Aneurysm 40

Aneurysm Biomarkers Hemorrhage Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP6-AWP6, February 1, 2025. Background and Purpose:Whether imaging markers of cerebral small vessel disease on computed tomography (CT-CSVD) relates to early clinical outcomes after intravenous thrombolysis for acute ischemic stroke remains not well understood. 1.95, p = 0.019).Conclusion:This

Thrombolysis 40

Thrombolysis Outcomes Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A74-A74, February 1, 2025. There is a need for surrogate imaging biomarkers that more strongly associate with functional outcome, to refine prognostication and facilitate development of EVT-adjuvant neuroprotective therapies. MRI was performed 1248 hours post-EVT.

Biomarkers 40

Biomarkers Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP320-ATP320, February 1, 2025. The alterations in this pathway have been confirmed in psychiatric disorders, but their role in stroke remains unclear. The alterations in this pathway have been confirmed in psychiatric disorders, but their role in stroke remains unclear.

Stroke 40

Stroke Strokes Biomarkers Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP385-ATP385, February 1, 2025. Emerging research suggests that Vitamin D3 might help protect against brain damage caused by ischemic stroke, as a deficiency in Vitamin D3 can worsen the severity and outcomes of a stroke.

Diet 40

Diet Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP79-AWMP79, February 1, 2025. Background and Purpose:The inflammatory response after ischemic and hemorrhagic stroke is associated with worse clinical outcomes through immune mediated production of pro- inflammatory cytokines. Of 25 enrolled patients, mean age was 65.8 (SD,

Exercise 40

Exercise Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP272-AWP272, February 1, 2025. However, there are no existing data supporting an independent relationship between cancer and atrial cardiopathy, another atrial pathology associated with increased acute ischemic stroke (AIS) risk.

Cancer 40

Cancer Stroke Strokes Atrial Fibrillation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A47-A47, February 1, 2025. Introduction:The rapid identification of acute intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke is decisive for prehospital triage and initiation of targeted therapies. Blood samples were collected in the prehospital phase.

Hemorrhage 40

Hemorrhage Stroke Strokes Blood Pressure 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP20-AWP20, February 1, 2025. This study aims to investigate whether RIC affects RBC deformability and levels of NO and nitrite in ischemic stroke patients.Methods:This is a predefined sub-study to the RESIST randomized clinical trial. median fluorescence intensity[MFI], Sham: 34.98

Stroke 40

Stroke Strokes Biomarkers Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A14-A14, February 1, 2025. Funding:The INSIGHT Registry is funded by Penumbra.Introduction:Rapid and precise determination of the etiology of acute ischemic stroke is crucial in long-term management and prevention of recurrence.

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Atrial Fibrillation Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP387-AWP387, February 1, 2025. Background:Metabolomics is commonly used to search for acute ischemic stroke (AIS) biomarkers. However, many studies which found metabolite - AIS associations have contradictory findings, which prevents solid conclusion.

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Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP112-ATMP112, February 1, 2025. Introduction:Both histological and transcriptomic analyses of acute ischemic stroke (AIS) clots have identified features associated with mechanical thrombectomy (MT) outcome.

Outcomes 40

Outcomes Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP42-AWMP42, February 1, 2025. Background:The Medical Research Council (MRC) scale is used to assess the impact of stroke on muscle strength. Shoulder abduction and finger extension, collectively (SAFE), have been suggested to have prognostic value for stroke outcomes (e.g.

Research 40

Research Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP338-AWP338, February 1, 2025. Introduction:Extracranial carotid artery pathology accounts for 15-20% of ischemic strokes. Furthermore, these patients could benefit from early surgical intervention if these biomarkers were to be detected.

Plaque 40

Plaque Biomarkers Risk Factors Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP105-AWMP105, February 1, 2025. Introduction:Accurate prediction of the risk of ischemic stroke (IS) is vital for prevention and would be aided by multimodal biomarkers integrating genetic, clinical, and functional data.

Stroke 40

Stroke Strokes Atrial Fibrillation Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP25-ATMP25, February 1, 2025. Introduction:Glial fibrillary acidic protein (GFAP), highly brain-specific, is emerging as an attractive blood biomarker in acute stroke. from onset, and 28% were wake-up strokes. 24h), and ASPECTS score (8-10 vs. <8).Results:Among

Stroke 40

Stroke Strokes Technology Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack.

Thrombosis 40

Thrombosis Obesity Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP226-AWP226, February 1, 2025. Specific biomarkers of platelet activity would improve our understanding of HE and could point towards targeted treatments. Globus New Investigator Award in Stroke aspirin, NSAIDs) is associated with increased HE.

Hemorrhage 40

Hemorrhage Biomarkers Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP318-AWP318, February 1, 2025. Background:Approximately 50% of ischemic strokes in patients with cancer are classified as cryptogenic after standard evaluation. Enrolled patients consented to screening for atrial cardiopathy, the presence of which was required for randomization.

Cancer 40

Cancer Biomarkers Atrial Fibrillation Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP209-ATP209, February 1, 2025. This workflow, which involves downloading imaging data from a clinical trials electronic data capture (EDC) system, performing biomarker analyses, and then re-entering data into the EDC, can be cumbersome when performed manually.

Download 40

Download Biomarkers Hemorrhage Research 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP224-AWP224, February 1, 2025. Background:The astroglial protein GFAP (glial fibrillary acidic protein) is a promising biomarker candidate for prehospital differentiation between intracerebral hemorrhage (ICH) and ischemic stroke.

Hemorrhage 40

Hemorrhage Biomarkers Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP54-ADP54, February 1, 2025. Background:Randomized trials and observational of patients with cervical artery dissection showed no significant difference in ischemic stroke risk with anticoagulation versus antiplatelet therapy. The outcome was ischemic stroke during follow up.

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Stroke Strokes Biomarkers Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP370-AWP370, February 1, 2025. Previous studies have identified numerous biomarkers, such as coagulation and platelet factors, which may predict patients at-risk for DCI, but to-date, no markers are widely utilized in the clinical setting.

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Ischemia Hemorrhage Biomarkers Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP397-AWP397, February 1, 2025. Backgrounds:Our prior work demonstrated the upregulation of miR-200 family miRNAs specifically miR-141&miR-200c after stroke in mice models. The inhibition of miR-141/200c restored the levels ofTgf2, Smad2&Zeb1.Conclusion:Cluster

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Stroke Strokes Biomarkers 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP232-AWP232, February 1, 2025. Conclusion:Spot sign visualized in conventional vascular imaging is a highly specific radiological biomarker for predicting mortality and poor functional outcomes in patients with ICH. For poor functional outcomes, OR was 4.13 (95% CI: 3.15-5.42;I2=33%).Conclusion:Spot

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Hemorrhage Outcomes Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP97-AWMP97, February 1, 2025. At baseline, DTI-ALPS was significantly correlated with PSQI (r = -0.174, p = 0.005) and various imaging biomarkers of CSVD after adjusting for age, gender, vascular risk factors, and ApoE4.

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Risk Factors Biomarkers Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP16-AWMP16, February 1, 2025. The quantified biomarker of this pattern can be used to monitor the decline in cognitive function. Pseudocontinuous arterial spin labeling imaging was used to identify hypoperfused regions (HypoR) in the discovery cohort.

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Biomarkers Stenosis Research Stroke 40