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Abstract WP230: Neuroinflammation Biomarker in the Course and Prognosis of Hemorrhagic Strokes

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP230-AWP230, February 1, 2025. Hemorrhagic strokes (HS) are increasingly significant causes of disability and mortality worldwide, making the use of blood biomarkers for their diagnosis and prognosis critical.

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Abstract WP227: Physiological Magnetic Resonance Imaging Biomarkers for Early Detection of Microvascular Dysfunction in Acute Intracerebral Hemorrhage

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP227-AWP227, February 1, 2025. Introduction:Intracerebral hemorrhage (ICH) is commonly associated with poor neurologic outcomes. Early intervention has been shown to improve patient prognosis, highlighting the necessity of sensitive biomarkers. Specifically, functional parameters (i.e.,

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Abstract WP35: Neutrophil Extracellular Traps As a Biomarker for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). Finally, as neutrophil counts (and the ratio of neutrophils to lymphocytes) are reported to be a biomarker for DCI, we assessed these measures too.

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Abstract TMP1: Identification of True Biomarkers for Unruptured Cerebral Aneurysms through Revisiting Cerebral Aneurysm Transcriptomes

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATMP1-ATMP1, February 1, 2025. A cerebral aneurysm (CA) is an abnormal artery deformation in the brain that may lead to hemorrhagic stroke, brain damage, coma, and even death when a CA ruptures. We hypothesized that increasing CA sample size will allow more robust biomarker identification.

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Abstract TP44: Alpha-1-acid glycoprotein is a potential serum Biomarker for Cerebral Amyloid Angiopathy

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP44-ATP44, February 1, 2025. It is closely linked to Alzheimer's disease (AD) and predisposes elderly patients to intracerebral hemorrhage and cognitive impairment. However, no effective serum biomarker has been established for early diagnosis or prediction of the disease progression.

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Abstract WP226: Thrombin-Mediated Platelet Activity Predicts Hematoma Expansion After Spontaneous Intracerebral Hemorrhage

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP226-AWP226, February 1, 2025. Objective:Hematoma expansion (HE) predicts disability and death after intracerebral hemorrhage (ICH). Specific biomarkers of platelet activity would improve our understanding of HE and could point towards targeted treatments.

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Abstract WMP32: Cross-Platform Proteomics and Machine Learning Algorithms Nominate Biomarkers of Stroke Diagnosis: An Exploratory Study

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWMP32-AWMP32, February 1, 2025. Our outcomes were differentially expressed protein (DEP) levels between patients with acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), transient ischemic attack (TIA), and stroke mimics (MIM). For pairwise comparisons, we identified the DEPs using 1.5-fold