Remove 2025 Remove Biomarkers Remove Dementia
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The Best Way To Prevent Dementia

Dr. Paddy Barrett

More than heart disease or cancer, dementia is the primary concern for many of the patients I see. Heart disease and cancer attack your body, but dementia attacks your mind and identity. That is why I believe people fear dementia so much. Thankfully, 45% of all dementia is preventable 1. That factor is exercise.

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Abstract WP49: Diagnostic performance of plasma pTau217 for the detection of Cognitive Impairment in a Vascular Disease-Enriched Population

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP49-AWP49, February 1, 2025. While plasma pTau217 is an established biomarker for AD, its relevance in vascular disease-enriched populations has not been extensively studied. Plasma pTau217 levels were found to be elevated in individuals with MCI and dementia.

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Abstract WP45: MRI-Visible Perivascular Spaces and Cognitive Performance: A Cross-Sectional Analysis from The Framingham Heart Study

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP45-AWP45, February 1, 2025. They are key indicators of cerebral small vessel disease (CSVD) and are associated with mild cognitive impairment (MCI) and dementia. These findings suggest a role for MRI-visible PVS as an early biomarker for the identification of those at risk of MCI or dementia.

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Abstract TP378: Malondialdehyde as a Clinical Indicator for Oxidative Stress: Associations with Age, BMI, and Cognitive Impairment

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP378-ATP378, February 1, 2025. Accumulation of oxidative stress has been shown to trigger the initiation and progression of cognitive deficits, including mild cognitive impairment (MCI) and Alzheimers Dementia (AD).

BMI 40
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Chest pain followed by 6 days of increasing dyspnea -- what happened?

Dr. Smith's ECG Blog

Written by Magnus Nossen, edits by Smith The patient in today's case is an 85-year-old male with a history of COPD and dementia. Due to very severe dementia, it was impossible to obtain a detailed history. link] == MY Comment , by K EN G RAUER, MD ( 1/14 /2025 ): == I found today's case highly insightful with regard to many aspects.

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The legal case – naming a few names

Dr. Malcolm Kendrick

(2022-25) Swiss Reinsurance Company: £645K China Kadoorie Biobank (2002-ongoing) AstraZeneca: $300K Bayer AG: £300K GlaxoSmithKline: £3.6M Elinogrel feasibility trial (2010-2011) Novartis: £500K EMPA-KIDNEY (2017-ongoing) Boehringer Ingelheim: £106.3M Establishing Fuwai-Oxford research centre (2010-ongoing) Merck: £1.1M