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METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Stroke, Volume 56, Issue Suppl_1 , Page AWP56-AWP56, February 1, 2025. Introduction:Prior studies have shown the association between oral infection, white matter hyperintensity (WMH), a marker of cerebral small vessel disease (CSVD), and asymptomatic intracranial atherosclerosis (ICAS).
tim.hodson Mon, 03/31/2025 - 10:26 March 31, 2025 AGEPHA Pharma USA, LLC, has released clinical data that provides new information about how low-dose colchicine, 0.5 mg can prevent heart attack and stroke in high-risk patients with established cardiovascular disease. These new data reinforce the use of LODOCO(colchicine, 0.5
Stroke, Volume 56, Issue Suppl_1 , Page AWP292-AWP292, February 1, 2025. Background:Intracranial atherosclerosis (ICAS) is a common stroke cause, with a recurrent stroke risk of up to 18% per year despite treatment advances. The primary outcome was the incidence of stroke. The weighted mean age was 63.7
Stroke, Volume 56, Issue Suppl_1 , Page A41-A41, February 1, 2025. This is largely due to the Stenting and Aggressive Medical Management Therapy for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial results which featured a high periprocedural stroke rate.
Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. Evidence has shown that carotid artery geometries are independently associated with ipsilateral MCA atherosclerosis. Demographic data, risk factors and the history of ischemic stroke of all patients were recorded. 21.35), p<0.001).Conclusions:Both
Stroke, Volume 56, Issue Suppl_1 , Page A110-A110, February 1, 2025. Background:Recent studies have shown that the autonomic nervous system plays a crucial role in regulating the initiation and progression of atherosclerosis in peripheral arteries.
Stroke, Volume 56, Issue Suppl_1 , Page ATP288-ATP288, February 1, 2025. Carotid atherosclerosis (CAS) is a critical precursor to atherosclerotic cardiovascular disease and is closely associated with the development and progression of conditions such as stroke and poor prognosis. 2021-KY-1289-001).Results:Among
Stroke, Volume 56, Issue Suppl_1 , Page ATP222-ATP222, February 1, 2025. Background:Symptomatic intracranial atherosclerotic disease carries a high stroke recurrence rate. Accurate prediction of stroke recurrence is critical for improving patient outcomes through timely and targeted interventions.
Stroke, Volume 56, Issue Suppl_1 , Page ATP311-ATP311, February 1, 2025. Introduction:Immune Checkpoint Inhibitors (ICIs) used for treatment of malignancies might promote atherosclerosis and increase the risk of ischemic stroke (IS). We collected demographics and stroke characteristics. range 27-386) vs. ICI 337.5
Stroke, Volume 56, Issue Suppl_1 , Page AWP268-AWP268, February 1, 2025. Introduction:The overall composition of stroke subtype is typically stable within biogeographical groups. Whether the COVID-19 pandemic impacted stroke etiology is still being investigated, but most studies have been performed outside the United States.
Stroke, Volume 56, Issue Suppl_1 , Page ATP332-ATP332, February 1, 2025. Introduction:Subclinical hyperthyroidism has been linked to an increased risk of atrial fibrillation, which elevates the likelihood of cardioembolism, cryptogenic stroke (CS), and embolic stroke of undetermined source (ESUS). 4.2uIU/mL).
Stroke, Volume 56, Issue Suppl_1 , Page AWMP73-AWMP73, February 1, 2025. Background:During the course of an ischemic stroke hospitalization, the initial diagnosis of the causative mechanism or etiology of stroke may evolve.
Stroke, Volume 56, Issue Suppl_1 , Page AWP23-AWP23, February 1, 2025. Introduction:Acute ischemic stroke is the second leading cause of death worldwide. Levels of LDL-C were correlated with the risk of recurrent stroke or transient ischemic attack (TIA). to 0.98, p= 0.04, and 0.88, 95% CI: 0.78 to 0.98, p= 0.03).
Stroke, Volume 56, Issue Suppl_1 , Page ATP326-ATP326, February 1, 2025. This finding may suggest that AF detected on an insertable cardiac monitor in cryptogenic stroke is often not pathogenic. The primary predictor was stroke subtype (ESUS vs. non-cardioembolic). ESUS was defined using the ESUS consensus criteria.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP73-ATMP73, February 1, 2025. Background:The therapeutic time window of endovascular therapy (EVT) for acute ischemic stroke (AIS) has been expanded up to 24 hours of onset. Patients were divided into 3 groups according to time from onset to hospital arrival (early: <4.5
Stroke, Volume 56, Issue Suppl_1 , Page AWP293-AWP293, February 1, 2025. Introduction:Migraine sufferers are at an increased risk of ischemic stroke which is one of the leading causes of disability worldwide. Conclusion:We report a possible association between migraine sufferers on SSRIs and risk for incident stroke.
Stroke, Volume 56, Issue Suppl_1 , Page AWP281-AWP281, February 1, 2025. Introduction:Determining ischemic stroke etiology using transthoracic echocardiography (TTE) is often considered to be a standard part of routine stroke care and secondary prevention of stroke. Risk of positive findings was 6.2%
Stroke, Volume 56, Issue Suppl_1 , Page ATP324-ATP324, February 1, 2025. We compared clinical features including aPL between the groups by each stroke subtypes based on TOAST classification. p=0.006) while aPL were not significantly different in other stroke subtypes. U/mL,p=0.047; LAC 1.15 U/mL,p=0.047; LAC 1.15
Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025. Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management.
Stroke, Volume 56, Issue Suppl_1 , Page ATP293-ATP293, February 1, 2025. Background and Objectives:Left subclavian artery (LSA) is more prone to atherosclerosis than the right one. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In
Stroke, Volume 56, Issue Suppl_1 , Page AWMP107-AWMP107, February 1, 2025. Background:Early detection of carotid artery (CA) conditions such as atherosclerosis and dissection are important as they represent major preventable causes of stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP8-ATMP8, February 1, 2025. Introduction:The role of alcohol consumption as an independent risk factor for atherosclerosis remains controversial. Carotid intima-media thickness (CIMT) is a recognized marker of atherosclerosis and can serve as a predictor of cardiovascular events.
Stroke, Volume 56, Issue Suppl_1 , Page ATP258-ATP258, February 1, 2025. Introduction:Mechanical thrombectomy (MT) devices were fundamentally designed for the treatment of cardioembolic (CE) strokes despite that 10-20% of large vessel occlusions (LVO) are caused by large artery atherosclerosis (LAA), which may not respond comparably.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP98-ATMP98, February 1, 2025. The primary outcome was a composite of all-cause death, ischemic stroke or transient ischemic attack, and acute coronary syndrome within one year post-stroke.
Stroke, Volume 56, Issue Suppl_1 , Page A36-A36, February 1, 2025. Background:Intracranial atherosclerotic disease (ICAD), a common cause of stroke, is associated with cerebral atrophy and cognitive impairment, but the underlying pathophysiology remains unknown.
tim.hodson Mon, 03/31/2025 - 10:26 March 31, 2025 AGEPHA Pharma USA, LLC, has highlighted clinical data that provides new information about how low-dose colchicine, 0.5 mg can prevent heart attack and stroke in high-risk patients with established cardiovascular disease. mg on atherosclerotic plaque.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP54-ATMP54, February 1, 2025. Background:Rapid, accurate diagnosis and characterization of carotid atherosclerosis can help prevent disabling strokes. Although carotid plaques can be identified on CT angiography (CTA), interpretation is challenging for frontline physicians.
Stroke, Volume 56, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2025. Methods:In this observational registry study, we reviewed patients from our comprehensive stroke center who underwent DSA from January 2013 to December 2023. Background and Objectives:Vertebral artery hypoplasia (VAH) is a common anatomical variation.
Stroke, Volume 56, Issue Suppl_1 , Page A108-A108, February 1, 2025. Introduction:Coagulation factor XI (FXI) inhibitors have shown a better safety profile than other anticoagulants, offering similar reductions in ischemic stroke (IS) risk with a lower risk of intracerebral hemorrhage (ICH).
Stroke, Volume 56, Issue Suppl_1 , Page ADP14-ADP14, February 1, 2025. Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive.
Stroke, Volume 56, Issue Suppl_1 , Page AWP376-AWP376, February 1, 2025. Introduction:Piezo1 is a mechanosensitive ion channel that gates calcium and sodium influx in response to membrane deformation or elevated shear stress.
Stroke, Volume 56, Issue Suppl_1 , Page ATP220-ATP220, February 1, 2025. Patients with clinically defined intracranial atherosclerotic vascular diseases or risk factors of atherosclerosis were available. Patients with ICAS having no or only mild stenosis (30%) of the ipsilateral extracranial ICA (C1) were included.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2025. This study investigates the association between CMB patterns and dementia risk in the community-based longitudinal Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).Methods:All
Stroke, Volume 56, Issue Suppl_1 , Page A135-A135, February 1, 2025. Introduction:Carotid artery tortuosity, characterized by abnormal vessel twisting, has been reported to be associated with various vascular pathologies and the presence of stroke. Black), 135 had an ischemic stroke over a median follow-up of 8.6
Stroke, Volume 56, Issue Suppl_1 , Page AWP388-AWP388, February 1, 2025. Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. SD), and 43.2%
Stroke, Volume 56, Issue Suppl_1 , Page AWP336-AWP336, February 1, 2025. Background:Trimethylamine N-oxide (TMAO), a gut microbiome-derived metabolite trimethylamine-containing nutrients, is mechanistically linked to atherosclerosis progression and platelet aggregation, leading to cardiovascular disease. p< 0.01).
Stroke, Volume 56, Issue Suppl_1 , Page A102-A102, February 1, 2025. Background and Purpose:Chronic kidney disease (CKD) is associated with an increased risk of stroke and worse outcomes, yet it is often asymptomatic, with an estimated 90% of individuals unaware they have CKD until its later stages. female, 22.1%
Stroke, Volume 56, Issue Suppl_1 , Page AWP310-AWP310, February 1, 2025. Background:Vascular risk factors, particularly in midlife, are associated with an increased risk of dementia, and smoking has been inversely associated with Parkinson's disease (PD) risk, but the role of these factors in PD-dementia (PDD) is less clear.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP24-AWMP24, February 1, 2025. Low HRV (L-HRV) is linked to an increased risk for ischemic stroke. White Matter Hyperintensities (WMH) is a measure of cerebral small vessel disease (cSVD) which is associated with lacunar ischemic stroke.
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