Remove 2025 Remove Arterioles Remove Exercise
article thumbnail

The 5-HT7 receptor contributes to increased hindquarter blood flow caused by skeletal muscle contraction.

Journal of Cardiovascular Pharmacology

Serotonin (5-hydroxytryptamine, 5-HT) at low plasma concentrations reduces blood pressure and dilates some skeletal muscle arterioles in the rat. Left anterior descending (LAD) coronary arterial ligation was used to create a model of impaired hindquarter perfusion and exercise intolerance. Copyright 2025 Wolters Kluwer Health, Inc.