Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP23-ADP23, February 1, 2025. Objective:The growth of unruptured intracranial aneurysms (IAs) is regarded as a critical precursor to aneurysmal rupture. The average age was 63.911.7 years, with 74.9%

Aneurysm 40

Aneurysm Risk Factors Hypertension Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP393-AWP393, February 1, 2025. Background and Purpose:Intracranial aneurysms (IAs) with daughter sacs (DSs) have an increased risk for rupture yet the hemodynamic factors contributing to DS pathophysiology are still under-investigated.

Aneurysm 40

Aneurysm Ablation Physiology Research 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP43-AWP43, February 1, 2025. Objective:Recanalized aneurysms may still recanalize despite a second coiling to prevent rupture. Factors related to recanalization following a second coiling for recanalized aneurysms have not yet been fully explored.

Aneurysm 40

Aneurysm Stent Stents Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP1-ATMP1, February 1, 2025. A cerebral aneurysm (CA) is an abnormal artery deformation in the brain that may lead to hemorrhagic stroke, brain damage, coma, and even death when a CA ruptures.

Aneurysm 40

Aneurysm Biomarkers Cardiomyopathy Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP397-ATP397, February 1, 2025. Steep intracranial pressure (ICP) rise constitutes a hallmark of aneurysmal subarachnoid hemorrhage (SAH). In the brain parenchyma, we observed minimal infiltration of circulating immune cells, consistent with the effects of aneurysm rupture.

Aneurysm 40

Aneurysm Hemorrhage Circulation Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A75-A75, February 1, 2025. Background:Female gender is a well-established risk factor for intracranial aneurysms (IA), with women showing a 3:1 prevalence, 2:1 rupture risk, and higher aneurysm multiplicity. This risk has also been recapitulated in IA mouse models. pg/ml vs 27.8

Aneurysm 40

Aneurysm Risk Factors Hypertension Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. In this study, our hypothesis was that markers of NETs are higher in aneurysmal SAH patients developing DCI compared to SAH patients not developing DCI. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH).

Aneurysm 40

Aneurysm Biomarkers Ischemia Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A76-A76, February 1, 2025. Introduction:Intracranial aneurysms (IAs) are abnormal dilations of brain arteries that can result in high mortality and morbidity when they rupture.

Aneurysm 40

Aneurysm Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A78-A78, February 1, 2025. Introduction:Intracranial aneurysm (IA), a cerebrovascular disease affecting 3-5% of US population, leads to subarachnoid hemorrage.

Aneurysm 40

Aneurysm Cerebrovascular Disease Circulation Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP2-ATMP2, February 1, 2025. Introduction:Flow diversion (FD) is a minimally invasive treatment for unruptured intracranial aneurysms (UIA) and is often preferred over open cerebrovascular surgery; however, FD patients are at risk of post-procedural stroke and hemorrhage.

Aneurysm 40

Aneurysm Hospital Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP258-AWP258, February 1, 2025. While shown to be effective and safe for treating intracranial aneurysms (IA), blood flow analysis is still limited. Introduction:Surpass Evolve (SE) is an updated flow diverter stent. For each case, a SE device measuring 3.25 respectively).

Aneurysm 40

Aneurysm Stent Stents Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP384-AWP384, February 1, 2025. Background:Small extracellular vesicles (sEVs) from blood samples of patients with cerebral aneurysms (CA) have been used as a biomarker for CA. However, biological function of sEVs in CA has not been studied.

Aneurysm 40

Aneurysm Biomarkers Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP4-ATMP4, February 1, 2025. Introduction:Early brain injury (EBI), a complex collection of pathophysiological processes occurring within 72 hours aneurysmal subarachnoid hemorrhage (aSAH), is the key link connecting the initial event to the delayed and long-term complications.

Aneurysm 40

Aneurysm Hemorrhage Biomarkers Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP88-ATMP88, February 1, 2025. Cerebrovascular conditions included brain or spine AVM, cavernous malformation, cerebral aneurysm, Moya-Moya vasculopathy, and/or unexplained hemorrhagic stroke. Individuals with perinatal or isolated arterial ischemic stroke were not included.

Pediatrics 40

Pediatrics Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP279-AWP279, February 1, 2025. The objective of this systematic review was to identify the factors associated with risk of stroke in patients hospitalized with IE.Methods:A systematic search of Ovid MEDLINE, EMBASE, and Web of Science was conducted between January 1990 and to July 2024.

Risk Factors 40

Risk Factors Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP367-AWP367, February 1, 2025. Introduction:Ischemia reperfusion injury (IRI) is a paradoxical and deleterious consequence of current interventions for acute ischemic stroke (AIS). Animals were pre-operatively randomized into vehicle (0.9% saline, N=5), medium dose DSM (0.5

Ischemia 40

Ischemia Stroke Strokes Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP329-ATP329, February 1, 2025. Background/Aim:Up to 20% of people have a hospital encounter in the 30 days before a first ever stroke, suggesting opportunities for better primary prevention. The reasons for these healthcare encounters before stroke have been largely unexplored.

Hospital 40

Hospital Stroke Strokes Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP100-ATP100, February 1, 2025. Introduction:Aneurysmal subarachnoid hemorrhage (aSAH) carries high morbidity and mortality. Survivors often require extended care at skilled nursing facilities (SNF) or long-term acute care centers (LTAC).

Nursing 40

Nursing Hemorrhage Aneurysm Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP38-AWP38, February 1, 2025. Introduction:Biomarkers combining blood-based gene expression and image-based features are an emerging method to detect and stratify intracranial aneurysms (IAs).

Aneurysm 40

Aneurysm Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ANS1-ANS1, February 1, 2025. Background:The 2023 American Heart Association/American Stroke AssociationsGuideline for Management of Patients with Aneurysmal Subarachnoid Hemorrhage(SAH) support use of the Ottawa Rule to screen individuals at risk.

Nursing 40

Nursing Hemorrhage RN Blood Pressure 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP50-ADP50, February 1, 2025. Among the subgroup of patients with known unruptured intracerebral aneurysms (n=8034), no difference in SAH with ACEI/ARBs was observed compared to alternative antihypertensive regimens [HR:1.04(0.95-1.13), 1.13), p=0.39] or no antihypertensive therapy [HR:1.06(0.97-1.16),

Hemorrhage 40

Hemorrhage Hypertension Aneurysm Pharmacology 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP31-AWP31, February 1, 2025. Neurovascular disorders- including stroke, brain aneurysm, and vascular malformations- strike an estimated seven million Americans annually and can lead to vascular pathologies, neurological disability, and death.

Pharmacology 40

Pharmacology Aneurysm Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP74-ATP74, February 1, 2025. Introduction:Extracranial-intracranial (EC-IC) bypass has evolved in recent years with more focus on indications, selection criteria, surgical methods, and postop management.

Inpatient 40

Inpatient Hospital Aneurysm Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP370-AWP370, February 1, 2025. Approximately 30% of aneurysmal subarachnoid hemorrhage (aSAH) patients who survive the rupture develop delayed cerebral ischemia (DCI) 4 to 10 days following aSAH.

Ischemia 40

Ischemia Hemorrhage Biomarkers Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP247-ATP247, February 1, 2025. Of the 32 patients, 9(28.1%) had dissection with diagnostic angiograms, 6(18.8%) endovascular thrombectomy, 15(46.9%) aneurysm treatment, and 2(6.3%) angioplasty with or without stenting.

Stent 40

Stent Stents Angioplasty Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP86-ATMP86, February 1, 2025. While certain angioarchitectural features, such as aneurysms, deep venous drainage, a single draining vein, venous outflow stenosis, or small nidus size, increase hemorrhage risk, they do not fully predict it.

Hemorrhage 40

Hemorrhage Pediatrics Aneurysm Stenosis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP153-ATP153, February 1, 2025. Background:According to the 2023 guidelines for the management of patients with aneurysmal subarachnoid hemorrhages (SAH), early treatment of ruptured aneurysms reduces the risk of repeated bleeds and facilitates treatment of delayed cerebral ischemia.

Aneurysm 40

Aneurysm Hospital Outcomes Stroke 40

DAIC

MARCH 11, 2025

Additional details on the AHA statement are available here. You can access the entire scientific statement by clicking here.

Research 52

Research Peripheral Arterial Disease Risk Factors Quality of Life 52

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2025. However, the causality between CHIP and aneurysm rupture, as well as the mechanism by which CHIP promotes aneurysm rupture, remains unclear. We evaluated the formation and rupture rates of intracranial aneurysms and the survival curve.

Aneurysm 40

Aneurysm Transplant Risk Factors Cancer 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A80-A80, February 1, 2025. Introduction:Although flow diverters (FD) are a long-established treatment-option for brain aneurysms, the evidence of data associated with therapy success is still based on relatively small heterogeneous studies. 91.7% (719) of aneurysms were saccular.

Aneurysm 40

Aneurysm Stent Stents Stenosis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP37-ADP37, February 1, 2025. Object:The introduction of antiplatelet agents is essential in stent-assisted coil embolization (SACE) for the treatment of intracranial aneurysms, and preoperative drug efficacy assessment is important in reducing the risk of ischemic complications.

Aneurysm 40

Aneurysm Stent Stents Embolism 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP26-AWP26, February 1, 2025. Additionaly, patients completed the Beck Depression Inventory and the Stroke Specific Quality of Life questionnaires, while their families completed the Iowa Scale of Personality Changes. Patients underwent Montreal Cognitive Assessment (MoCA).

Hemorrhage 40

Hemorrhage Aneurysm Quality of Life Ischemia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP218-ATP218, February 1, 2025. We aimed to evaluate the prevalence and characteristics of cerebrovascular fibromuscular dysplasia (cFMD) in a population-level cohort of patients with ischemic stroke(IS) and transient ischemic attack (TIA).Methods:We

Stroke 40

Stroke Strokes Risk Factors Aneurysm 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP3-ATMP3, February 1, 2025. Cerebral aneurysms (CA) arise from the sites of weakened artery walls in the brain, and they may cause hemorrhagic stroke, coma, and death when they rupture. Studies have revealed sex differences in ~1.5 times higher prevalence of CA and ~1.5

Biomarkers 40

Biomarkers Aneurysm Risk Factors Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP81-ATP81, February 1, 2025. These patients were admitted to a neuroscience intensive care unit (NSICU) at the only comprehensive stroke center within our health system. 1,2Clinical and radiographic predictors of early death and transition to comfort care may help guide IHT decisions.3In

Aneurysm 40

Aneurysm Hemorrhage Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP277-ATP277, February 1, 2025. Chi-square tests were used to compare HTPR by principal diagnosis, demographics (age, sex, race, comorbidities), laboratory findings, and AIS stroke subtype (TOAST classification).Results:The HTPR was identified in 50 patients (13%), Table 1.

Diabetes 40

Diabetes Laboratory Aneurysm Stroke 40