2025, Aneurysm and Hemorrhage - Cardiovascular Update

Abstract WP35: Neutrophil Extracellular Traps As a Biomarker for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). In this study, our hypothesis was that markers of NETs are higher in aneurysmal SAH patients developing DCI compared to SAH patients not developing DCI.

Aneurysm

Aneurysm Biomarkers Ischemia Hemorrhage

Abstract TMP4: Serum Protein Biomarekrs and Cell Suptypes Linked to Reduced Cerebral Edema in Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP4-ATMP4, February 1, 2025. Introduction:Early brain injury (EBI), a complex collection of pathophysiological processes occurring within 72 hours aneurysmal subarachnoid hemorrhage (aSAH), is the key link connecting the initial event to the delayed and long-term complications.

Aneurysm

Aneurysm Hemorrhage Biomarkers Stroke

Abstract TP377: A Biomarker Based on Aneurysm Wall Enhancement and Blood Gene Expression to Identify Symptomatic Intracranial Aneurysms

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP377-ATP377, February 1, 2025. Introduction:Intracranial aneurysms (IAs) are weak outpouchings on cerebral vessels that can rupture, causing subarachnoid hemorrhage. With the addition of the gene expression features, we found the PCA explained variance to be 41% and 26%.

Aneurysm

Aneurysm Biomarkers Hemorrhage Stroke

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Abstract TP100: Predictors of Skilled Nursing Facility Length of Stay and Discharge after Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP100-ATP100, February 1, 2025. Introduction:Aneurysmal subarachnoid hemorrhage (aSAH) carries high morbidity and mortality. Intraventricular hemorrhage (OR 0, 95% CI 0-1.12, p=0.043), tracheostomy (OR=0.14, 95% CI 0.14-1.01, Discharged patients were younger (mean 63.311.5

Nursing

Nursing Hemorrhage Aneurysm Hospital

Abstract TMP88: Clinical Utility of Genetic Testing in Pediatric and Young Adult Hemorrhagic Stroke and Cerebrovascular Malformations

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP88-ATMP88, February 1, 2025. Cerebrovascular conditions included brain or spine AVM, cavernous malformation, cerebral aneurysm, Moya-Moya vasculopathy, and/or unexplained hemorrhagic stroke. Individuals with perinatal or isolated arterial ischemic stroke were not included.

Pediatrics

Pediatrics Hemorrhage Stroke Strokes

Abstract TMP2: Flow diversion treatments for unruptured intracranial aneurysms: real-world perioperative outcomes, hospital readmissions, and impact of comorbid anxiety and mood disorders

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP2-ATMP2, February 1, 2025. Introduction:Flow diversion (FD) is a minimally invasive treatment for unruptured intracranial aneurysms (UIA) and is often preferred over open cerebrovascular surgery; however, FD patients are at risk of post-procedural stroke and hemorrhage.

Aneurysm

Aneurysm Hospital Hemorrhage Outcomes

Abstract TMP86: Stratifying risk of hemorrhage of pedatriac brain arteriovenous malformation using quantitative color-coded digital subtraction angiography and iflow analysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP86-ATMP86, February 1, 2025. Background:Pediatric brain arteriovenous malformation (bAVM) patients often present with intracranial hemorrhage. female), 47.5% (n=19) had a history of hemorrhage. Larger bAVM size was significantly associated with a lower likelihood of prior hemorrhage.

Hemorrhage

Hemorrhage Pediatrics Aneurysm Stenosis

Abstract DP50: Angiotensin inhibition reduces the risk of subarachnoid hemorrhage in patients with hypertension

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP50-ADP50, February 1, 2025. Background:Local angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, which contributes to the pathogenesis of subarachnoid hemorrhage (SAH). 1.13), p=0.39] or no antihypertensive therapy [HR:1.06(0.97-1.16),

Hemorrhage

Hemorrhage Hypertension Aneurysm Pharmacology

Abstract WP370: Platelet morphology but not coagulation markers predicts delayed cerebral ischemia after subarachnoid hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP370-AWP370, February 1, 2025. Approximately 30% of aneurysmal subarachnoid hemorrhage (aSAH) patients who survive the rupture develop delayed cerebral ischemia (DCI) 4 to 10 days following aSAH.

Ischemia

Ischemia Hemorrhage Biomarkers Aneurysm

Abstract NS1: Identification of Subarachnoid Hemorrhage: The Impact of a Nurse Led Screening Tool Utilizing the Ottawa Rule

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ANS1-ANS1, February 1, 2025. Background:The 2023 American Heart Association/American Stroke AssociationsGuideline for Management of Patients with Aneurysmal Subarachnoid Hemorrhage(SAH) support use of the Ottawa Rule to screen individuals at risk.

Nursing

Nursing Hemorrhage RN Blood Pressure

Abstract WP279: Predicting Stroke in Patients with Infective Endocarditis: A Comprehensive Systematic Review and Meta-Analysis of Risk Factors

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP279-AWP279, February 1, 2025. Introduction:Neurological complications in patients with infective endocarditis (IE), such as ischemic and hemorrhagic stroke, are well-described, serious complications of IE; however, predicting which patients are most likely to experience stroke remains uncertain.

Risk Factors

Risk Factors Stroke Strokes Hemorrhage

Abstract WP26: Determinants of Neuropsychological Function after Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP26-AWP26, February 1, 2025. Introduction:Aneurysmal subarachnoid hemorrhage (aSAH) survivors suffer cognitive and behavioral challenges preventing their return to work and social activities. The factors that may affect neuropsychological outcomes after aSAH are not well characterized.

Hemorrhage

Hemorrhage Aneurysm Quality of Life Ischemia

Abstract WMP114: Clonal hematopoiesis of indeterminate potential promotes the development of intracranial aneurysm rupture

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2025. CHIP is also considered a risk factor for subarachnoid hemorrhage. However, the causality between CHIP and aneurysm rupture, as well as the mechanism by which CHIP promotes aneurysm rupture, remains unclear. C57BL/6 CD45.1+/CD45.2-

Aneurysm

Aneurysm Transplant Risk Factors Cancer

Abstract TMP1: Identification of True Biomarkers for Unruptured Cerebral Aneurysms through Revisiting Cerebral Aneurysm Transcriptomes

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP1-ATMP1, February 1, 2025. A cerebral aneurysm (CA) is an abnormal artery deformation in the brain that may lead to hemorrhagic stroke, brain damage, coma, and even death when a CA ruptures.

Aneurysm

Aneurysm Biomarkers Hemorrhage Cardiomyopathy

Abstract TP397: Effect of Intracranial Pressure Spikes Modeling Subarachnoid Aneurysm Rupture on the Brain and Dura Barrier Immune System

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP397-ATP397, February 1, 2025. Steep intracranial pressure (ICP) rise constitutes a hallmark of aneurysmal subarachnoid hemorrhage (SAH). In the brain parenchyma, we observed minimal infiltration of circulating immune cells, consistent with the effects of aneurysm rupture.

Aneurysm

Aneurysm Hemorrhage Circulation Stroke

Abstract TP153: Review of Hospital Outcomes for Aneurysm Securement in SAH at a Midwest Comprehensive Stroke Center

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP153-ATP153, February 1, 2025. Background:According to the 2023 guidelines for the management of patients with aneurysmal subarachnoid hemorrhages (SAH), early treatment of ruptured aneurysms reduces the risk of repeated bleeds and facilitates treatment of delayed cerebral ischemia.

Aneurysm

Aneurysm Hospital Outcomes Stroke

Abstract TP74: Trends in extracranial-intracranial bypass procedure from 2016-2019

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP74-ATP74, February 1, 2025. Introduction:Extracranial-intracranial (EC-IC) bypass has evolved in recent years with more focus on indications, selection criteria, surgical methods, and postop management.

Inpatient

Inpatient Hospital Aneurysm Hemorrhage

Abstract TP81: Severity of Aneurysmal Subarachnoid Hemorrhage (aSAH) as a Predictor for Early Deterioration in Patients Undergoing Interhospital Transfer (IHT) in a Large Urban Health System

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP81-ATP81, February 1, 2025. Introduction:Patients with aSAH that are critically ill often undergo interhospital transfer (IHT) for multiple reasons including emergent treatment, physician second opinion, and patient preference.1,2Clinical

Aneurysm

Aneurysm Hemorrhage Stroke Strokes

Abstract TMP3: Identifying Sex-specific Biomarkers of Unruptured Cerebral Aneurysms through Revisiting Cerebral Aneurysm Transcriptomes

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP3-ATMP3, February 1, 2025. Cerebral aneurysms (CA) arise from the sites of weakened artery walls in the brain, and they may cause hemorrhagic stroke, coma, and death when they rupture. Studies have revealed sex differences in ~1.5 times higher prevalence of CA and ~1.5

Biomarkers

Biomarkers Aneurysm Risk Factors Hemorrhage

Abstract WP35: Neutrophil Extracellular Traps As a Biomarker for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

Abstract TMP4: Serum Protein Biomarekrs and Cell Suptypes Linked to Reduced Cerebral Edema in Aneurysmal Subarachnoid Hemorrhage

Abstract TP377: A Biomarker Based on Aneurysm Wall Enhancement and Blood Gene Expression to Identify Symptomatic Intracranial Aneurysms

Webinars

Abstract TP100: Predictors of Skilled Nursing Facility Length of Stay and Discharge after Aneurysmal Subarachnoid Hemorrhage

Abstract TMP88: Clinical Utility of Genetic Testing in Pediatric and Young Adult Hemorrhagic Stroke and Cerebrovascular Malformations

Abstract TMP2: Flow diversion treatments for unruptured intracranial aneurysms: real-world perioperative outcomes, hospital readmissions, and impact of comorbid anxiety and mood disorders

Abstract TMP86: Stratifying risk of hemorrhage of pedatriac brain arteriovenous malformation using quantitative color-coded digital subtraction angiography and iflow analysis

Abstract DP50: Angiotensin inhibition reduces the risk of subarachnoid hemorrhage in patients with hypertension

Abstract WP370: Platelet morphology but not coagulation markers predicts delayed cerebral ischemia after subarachnoid hemorrhage

Abstract NS1: Identification of Subarachnoid Hemorrhage: The Impact of a Nurse Led Screening Tool Utilizing the Ottawa Rule

Abstract WP279: Predicting Stroke in Patients with Infective Endocarditis: A Comprehensive Systematic Review and Meta-Analysis of Risk Factors

Abstract WP26: Determinants of Neuropsychological Function after Aneurysmal Subarachnoid Hemorrhage

Abstract WMP114: Clonal hematopoiesis of indeterminate potential promotes the development of intracranial aneurysm rupture

Abstract TMP1: Identification of True Biomarkers for Unruptured Cerebral Aneurysms through Revisiting Cerebral Aneurysm Transcriptomes

Abstract TP397: Effect of Intracranial Pressure Spikes Modeling Subarachnoid Aneurysm Rupture on the Brain and Dura Barrier Immune System

Abstract TP153: Review of Hospital Outcomes for Aneurysm Securement in SAH at a Midwest Comprehensive Stroke Center

Abstract TP74: Trends in extracranial-intracranial bypass procedure from 2016-2019

Abstract TP81: Severity of Aneurysmal Subarachnoid Hemorrhage (aSAH) as a Predictor for Early Deterioration in Patients Undergoing Interhospital Transfer (IHT) in a Large Urban Health System

Abstract TMP3: Identifying Sex-specific Biomarkers of Unruptured Cerebral Aneurysms through Revisiting Cerebral Aneurysm Transcriptomes

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