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Stroke, Volume 56, Issue Suppl_1 , Page AWP36-AWP36, February 1, 2025. Background:Up to 5% of patients with infective endocarditis (IE) develop intracranial mycotic aneurysms (MA) with nearly 25% of these patients having multiple intracranial aneurysms. Therefore, accurate diagnosis of intracerebral aneurysms is critical.
Stroke, Volume 56, Issue Suppl_1 , Page A81-A81, February 1, 2025. Background:Cerebral aneurysm rupture has a poor prognosis, and a growing aneurysm is prone to rupture. Although hemodynamics is thought to play an important role in aneurysm growth, it is not well understood what hemodynamic environments are involved.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP112-AWMP112, February 1, 2025. Introduction:Clinical studies have shown an association between aging and the risk of intracranial aneurysm rupture. We also confirmed that genetic elimination of senescent cells prevented aneurysm rupture. vs. 100%,P<0.05, Fig.
Stroke, Volume 56, Issue Suppl_1 , Page A77-A77, February 1, 2025. Background:Managing unruptured intracranial aneurysms (IAs) involves balancing procedural risks with the long-term risk of rupture. Aneurysm wall enhancement (AWE) has been associated with aneurysm instability and symptomatic presentation.
Stroke, Volume 56, Issue Suppl_1 , Page ATP377-ATP377, February 1, 2025. Introduction:Intracranial aneurysms (IAs) are weak outpouchings on cerebral vessels that can rupture, causing subarachnoid hemorrhage. With the addition of the gene expression features, we found the PCA explained variance to be 41% and 26%.
Stroke, Volume 56, Issue Suppl_1 , Page ADP23-ADP23, February 1, 2025. Objective:The growth of unruptured intracranial aneurysms (IAs) is regarded as a critical precursor to aneurysmal rupture. Accurately predicting aneurysm growth is crucial for appropriate therapeutic interventions to prevent rupture in high-risk aneurysms.
Stroke, Volume 56, Issue Suppl_1 , Page ATP162-ATP162, February 1, 2025. Background:Detection of intracranial aneurysms (IAs) is a time consuming and error prone process. The definition of the correct diagnosis of the location was that the center of the aneurysm diagnosed by the AI system is within the area of the IA of ground truth.
Stroke, Volume 56, Issue Suppl_1 , Page AWP393-AWP393, February 1, 2025. Background and Purpose:Intracranial aneurysms (IAs) with daughter sacs (DSs) have an increased risk for rupture yet the hemodynamic factors contributing to DS pathophysiology are still under-investigated.
Stroke, Volume 56, Issue Suppl_1 , Page AWP43-AWP43, February 1, 2025. Objective:Recanalized aneurysms may still recanalize despite a second coiling to prevent rupture. Factors related to recanalization following a second coiling for recanalized aneurysms have not yet been fully explored.
Stroke, Volume 56, Issue Suppl_1 , Page A75-A75, February 1, 2025. Background:Female gender is a well-established risk factor for intracranial aneurysms (IA), with women showing a 3:1 prevalence, 2:1 rupture risk, and higher aneurysm multiplicity. This risk has also been recapitulated in IA mouse models. pg/ml vs 27.8
Stroke, Volume 56, Issue Suppl_1 , Page ATP397-ATP397, February 1, 2025. Steep intracranial pressure (ICP) rise constitutes a hallmark of aneurysmal subarachnoid hemorrhage (SAH). In the brain parenchyma, we observed minimal infiltration of circulating immune cells, consistent with the effects of aneurysm rupture.
Stroke, Volume 56, Issue Suppl_1 , Page AWP35-AWP35, February 1, 2025. In this study, our hypothesis was that markers of NETs are higher in aneurysmal SAH patients developing DCI compared to SAH patients not developing DCI. Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH).
Stroke, Volume 56, Issue Suppl_1 , Page ATMP1-ATMP1, February 1, 2025. A cerebral aneurysm (CA) is an abnormal artery deformation in the brain that may lead to hemorrhagic stroke, brain damage, coma, and even death when a CA ruptures.
Stroke, Volume 56, Issue Suppl_1 , Page A76-A76, February 1, 2025. Introduction:Intracranial aneurysms (IAs) are abnormal dilations of brain arteries that can result in high mortality and morbidity when they rupture.
Stroke, Volume 56, Issue Suppl_1 , Page AWP258-AWP258, February 1, 2025. While shown to be effective and safe for treating intracranial aneurysms (IA), blood flow analysis is still limited. Introduction:Surpass Evolve (SE) is an updated flow diverter stent. For each case, a SE device measuring 3.25 respectively).
Stroke, Volume 56, Issue Suppl_1 , Page AWP384-AWP384, February 1, 2025. Background:Small extracellular vesicles (sEVs) from blood samples of patients with cerebral aneurysms (CA) have been used as a biomarker for CA. However, biological function of sEVs in CA has not been studied.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP4-ATMP4, February 1, 2025. Introduction:Early brain injury (EBI), a complex collection of pathophysiological processes occurring within 72 hours aneurysmal subarachnoid hemorrhage (aSAH), is the key link connecting the initial event to the delayed and long-term complications.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP2-ATMP2, February 1, 2025. Introduction:Flow diversion (FD) is a minimally invasive treatment for unruptured intracranial aneurysms (UIA) and is often preferred over open cerebrovascular surgery; however, FD patients are at risk of post-procedural stroke and hemorrhage.
Stroke, Volume 56, Issue Suppl_1 , Page ATP100-ATP100, February 1, 2025. Introduction:Aneurysmal subarachnoid hemorrhage (aSAH) carries high morbidity and mortality. Survivors often require extended care at skilled nursing facilities (SNF) or long-term acute care centers (LTAC).
Stroke, Volume 56, Issue Suppl_1 , Page AWP38-AWP38, February 1, 2025. Introduction:Biomarkers combining blood-based gene expression and image-based features are an emerging method to detect and stratify intracranial aneurysms (IAs).
Stroke, Volume 56, Issue Suppl_1 , Page AWP367-AWP367, February 1, 2025. Infarct volume was calculated on diffusion weighted imaging (DWI) at each time-point to assess ischemic evolution.Results:All animals displayed evidence of MCAo and successful reperfusion following aneurysm clip removal (Figure 1). mmole/min; N=4).
Stroke, Volume 56, Issue Suppl_1 , Page ADP50-ADP50, February 1, 2025. Among the subgroup of patients with known unruptured intracerebral aneurysms (n=8034), no difference in SAH with ACEI/ARBs was observed compared to alternative antihypertensive regimens [HR:1.04(0.95-1.13), 1.13), p=0.39] or no antihypertensive therapy [HR:1.06(0.97-1.16),
Stroke, Volume 56, Issue Suppl_1 , Page AWP279-AWP279, February 1, 2025. Risk of ICH was heightened by thrombocytopenia, mycotic aneurysms, prior ICH and/or AIS, and cerebral microbleeds.Conclusion:Physicians need to monitor numerous, diverse features of patients hospitalized with IE to mitigate the risk of ensuing stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATP74-ATP74, February 1, 2025. Introduction:Extracranial-intracranial (EC-IC) bypass has evolved in recent years with more focus on indications, selection criteria, surgical methods, and postop management.
Stroke, Volume 56, Issue Suppl_1 , Page AWP370-AWP370, February 1, 2025. Approximately 30% of aneurysmal subarachnoid hemorrhage (aSAH) patients who survive the rupture develop delayed cerebral ischemia (DCI) 4 to 10 days following aSAH.
Stroke, Volume 56, Issue Suppl_1 , Page AWP31-AWP31, February 1, 2025. Neurovascular disorders- including stroke, brain aneurysm, and vascular malformations- strike an estimated seven million Americans annually and can lead to vascular pathologies, neurological disability, and death.
Stroke, Volume 56, Issue Suppl_1 , Page ATP329-ATP329, February 1, 2025. carotid artery stenosis and unruptured cerebral aneurysm), abnormal symptoms or pathological findings (e.g. The reasons for these healthcare encounters before stroke have been largely unexplored. convulsions and headache), nervous system disorders (e.g.
Stroke, Volume 56, Issue Suppl_1 , Page ATP247-ATP247, February 1, 2025. Of the 32 patients, 9(28.1%) had dissection with diagnostic angiograms, 6(18.8%) endovascular thrombectomy, 15(46.9%) aneurysm treatment, and 2(6.3%) angioplasty with or without stenting.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP86-ATMP86, February 1, 2025. While certain angioarchitectural features, such as aneurysms, deep venous drainage, a single draining vein, venous outflow stenosis, or small nidus size, increase hemorrhage risk, they do not fully predict it.
Stroke, Volume 56, Issue Suppl_1 , Page ANS1-ANS1, February 1, 2025. Background:The 2023 American Heart Association/American Stroke AssociationsGuideline for Management of Patients with Aneurysmal Subarachnoid Hemorrhage(SAH) support use of the Ottawa Rule to screen individuals at risk.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2025. However, the causality between CHIP and aneurysm rupture, as well as the mechanism by which CHIP promotes aneurysm rupture, remains unclear. We evaluated the formation and rupture rates of intracranial aneurysms and the survival curve.
Stroke, Volume 56, Issue Suppl_1 , Page ATP153-ATP153, February 1, 2025. Background:According to the 2023 guidelines for the management of patients with aneurysmal subarachnoid hemorrhages (SAH), early treatment of ruptured aneurysms reduces the risk of repeated bleeds and facilitates treatment of delayed cerebral ischemia.
Stroke, Volume 56, Issue Suppl_1 , Page A80-A80, February 1, 2025. Introduction:Although flow diverters (FD) are a long-established treatment-option for brain aneurysms, the evidence of data associated with therapy success is still based on relatively small heterogeneous studies. Median diameter and neck width of aneurysms were 7.2
tim.hodson Tue, 03/11/2025 - 11:02 March 11, 2025 The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Associations (..)
Stroke, Volume 56, Issue Suppl_1 , Page ADP37-ADP37, February 1, 2025. Object:The introduction of antiplatelet agents is essential in stent-assisted coil embolization (SACE) for the treatment of intracranial aneurysms, and preoperative drug efficacy assessment is important in reducing the risk of ischemic complications.
Stroke, Volume 56, Issue Suppl_1 , Page AWP26-AWP26, February 1, 2025. Introduction:Aneurysmal subarachnoid hemorrhage (aSAH) survivors suffer cognitive and behavioral challenges preventing their return to work and social activities. The factors that may affect neuropsychological outcomes after aSAH are not well characterized.
Stroke, Volume 56, Issue Suppl_1 , Page ATMP3-ATMP3, February 1, 2025. Cerebral aneurysms (CA) arise from the sites of weakened artery walls in the brain, and they may cause hemorrhagic stroke, coma, and death when they rupture. Studies have revealed sex differences in ~1.5 times higher prevalence of CA and ~1.5
Stroke, Volume 56, Issue Suppl_1 , Page ATP81-ATP81, February 1, 2025. Introduction:Patients with aSAH that are critically ill often undergo interhospital transfer (IHT) for multiple reasons including emergent treatment, physician second opinion, and patient preference.1,2Clinical
Stroke, Volume 56, Issue Suppl_1 , Page ATP218-ATP218, February 1, 2025. Concomitant intracranial or extracranial aneurysms were detected in 9.1%(Table Introduction:Fibromuscular dysplasia (FMD) is a rare, nonatherosclerotic, non-inflammatory vasculopathy for which only limited population-level data are available.
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