Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP117-ATP117, February 1, 2024. Introduction:Reducing door-to-needle (DTN) times lead to improved patient outcomes in acute ischemic stroke. 2) Creation of a multidisciplinary Thrombolysis Focus Group to analyze data and improve processes. in 2020, to 31.9% in 2021, to 59.6%

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Thrombolysis Academic Document Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A26-A26, February 1, 2024. The access to acute stroke treatments, especially intravenour thrombolysis and mechanical thrombectomy, is limited. The average stroke centres per million (SCPM) population was 0.41 for IVT-C and EVT-C, respectively. hours, respectively.

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Thrombolysis Stroke Strokes Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP270-ATP270, February 1, 2024. Objective:A proportion of acute ischemic stroke (AIS) patients suffer from early neurological deterioration (END) within 24 hours following intravenous thrombolysis (IVT), which greatly increases the risk of poor prognosis of these patients.

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Thrombolysis BMI Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP213-ATP213, February 1, 2024. Background and Purpose:Although intra-arterial thrombolysis (IAT) is widely used as adjunct with mechanical thrombectomy in acute ischemic stroke patients, the patients who are likely to benefit are not known. in group A and 3.25±2.01

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Thrombolysis Stroke Strokes Stent 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP20-AWP20, February 1, 2024. Importance:Tenecteplase use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke, with results demonstrating its non-inferiority compared to alteplase.

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Hemorrhage Thrombolysis Stroke Strokes 40

DAIC

FEBRUARY 26, 2024

Kulcsar, University Hospital Zurich milla1cf Mon, 02/26/2024 - 12:13 February 26, 2024 — Ischemic strokes are a major health burden. Many stroke patients recover poorly despite timely treatment To treat these symptoms and restore blood flow to the brain, the obstructed vessel needs to be “declogged”, or recanalized.

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Blood Clot Stroke Strokes Outcomes 105

Stroke: Vascular and Interventional Neurology

APRIL 17, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print.

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DAIC

FEBRUARY 7, 2024

Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. 9 Phoenix, AZ. Adeoye, M.D.,

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Stroke Strokes Outcomes Thrombolysis 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A22-A22, February 1, 2024. Introduction:The benefit of intravenous thrombolysis for acute ischemic stroke declines with longer time from symptom onset. Intravenous thrombolysis showed clinical benefit if it was administered within 2h 20min after symptom onset.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP13-ATMP13, February 1, 2024. Introduction:Recent studies report similar outcomes with antiplatelet drugs and intravenous thrombolysis (IVT) in patients with minor nondisabling ischemic stroke.

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Thrombolysis Stroke Strokes Academic 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP5-AWMP5, February 1, 2024.

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Thrombolysis Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP93-AWMP93, February 1, 2024. Introduction:Comprehensive Stroke Centers are skilled, highly trained facilities that provide advanced care to an array of stroke patients. Ideally, these Primary Centers save time to intervention.

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Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A25-A25, February 1, 2024. Introduction:Intravenous thrombolysis (IVT) is efficacious treatment of acute ischemic stroke (AIS). However, certain circumstances associated with increased bleeding risk, such as recent direct oral anticoagulation (DOAC) intake limits its use.

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Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP202-AWP202, February 1, 2024. Background:Mechanical thrombectomy (MT) has demonstrated superiority over medical therapy for acute ischemic stroke (AIS) with large vessel occlusion (LVO).

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Thrombolysis Academic Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP42-AWMP42, February 1, 2024. Background:Prior studies have shown that individuals who have an in-hospital stroke are less likely to receive thrombolysis. Out of hospital strokes were patients who were not admitted to the hospital when their stroke symptoms.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A106-A106, February 1, 2024. Background:Circulating interleukin-6 (IL-6) concentrations are elevated in acute stroke but the timing of the IL-6 response in humans is unknown. We used a mobile stroke unit (MSU) to identify IL-6 levels within minutes of symptom onset.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP179-AWP179, February 1, 2024. Background:Stent-retriever thrombectomy is the first-line therapy for acute stroke with intracranial large vessel occlusion.

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Stent Stents Thrombolysis Angioplasty 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP199-AWP199, February 1, 2024. Background:The benefits of endovascular thrombectomy (EVT) for posterior cerebral artery (PCA) occlusion remain controversial, but intravenous thrombolysis (IVT) has proven benefit across nearly all ischemic stroke types.

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Atrial Fibrillation Thrombolysis Outcomes Embolism 40

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 186-189, January 1, 2024.

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Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP282-ATP282, February 1, 2024. Background:This analysis is based on a prospective database encompassing consecutive patients who underwent EVT for LVO between January 2021 and June 2023 at a comprehensive stroke center (CSC).Main vs. 70.6 ± 14.5). min vs. 394.5 min vs. 45.1 hours vs. 59.3

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP104-ATP104, February 1, 2024. Introduction:Accurate outcome prognostication in acute ischemic stroke (AIS) informs essential medical decision-making for clinicians, patients, and families. Cases with a modified Rankin scale (mRS) of 0-2 at 90 days (i.e.

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Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP8-AWP8, February 1, 2024. Median time from the onset of visual change to thrombolysis was 6.0 [4.5-10.5] Introduction:Branch retinal artery occlusion (BRAO) results from the blood flow compromise in of the branches of the central retinal artery. VA improvement of ≥0.1

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Thrombolysis Outcomes Hemorrhage Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP278-ATP278, February 1, 2024. Subjects were divided into "intravenous thrombolysis group" and "non-intravenous thrombolysis group". Result:A total of 1971 patients (437 thrombolysis) were included. AIS with premorbid mRS ≤ 2 within 72 hours of onset was included.

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Thrombolysis Thrombosis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP154-AWP154, February 1, 2024. Prolonged ICU stay were more likely to have higher baseline median NIHSS score (19 vs. 14%, p < 0.0001), posterior circulation stroke (12.6% Patients receiving thrombolysis prior to thrombectomy were less likely to have a prolonged LOS (27.8%

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ICU Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP23-ATMP23, February 1, 2024. Background:Studies have reported longer emergency department (ED) wait times and delayed stroke treatment for Black versus White patients. Minority patients also have severe stroke symptoms compared to White patients.

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Stroke Strokes Thrombolysis Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP108-ATP108, February 1, 2024. Introduction:The Alberta Stroke Program Early CT Score (ASPECTS) is often used in considering whether patients are appropriate for thrombolysis and/or thrombectomy after acute ischemic stroke (AIS).

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Stroke Strokes Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP82-ATP82, February 1, 2024. Introduction:The incidence of Large Vessel Occlusion-Acute Ischemic Stroke (LVO-AIS) continues to increase in young adults. 31 patients (18%) had stroke etiology as Large Artery Atherosclerosis (per TOAST criteria). received IV thrombolysis and 43.9%

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Stroke Strokes Atherosclerosis Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A89-A89, February 1, 2024. Background and Aims:Treatment options for acute ischemic stroke (AIS) are uniquely dependent on the time of stroke onset. Intravenous thrombolysis must be administered within 4.5 Intravenous thrombolysis must be administered within 4.5

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Stroke Strokes Thrombolysis Technology 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A34-A34, February 1, 2024. A change in the stroke alert process (January 2023) focused on early notification of stroke alert, CT and telestroke. After changing the ED stroke process, there was a reduction in DTN of 29.26

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Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP21-AWP21, February 1, 2024. Introduction:Although prior antiplatelet therapy (APT) could potentially contribute to bleeding risk, the influence of prior APT on intravenous thrombolysis outcomes remains controversial.

Stroke 40

Stroke Strokes Thrombolysis Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP26-AWP26, February 1, 2024. Introduction:Tenecteplase is increasingly utilized as an alternative acute ischemic stroke (AIS) thrombolytic to Alteplase (tPA). We utilized the Get With the Guidelines (GWTG) database to obtain basic demographic data.

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Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A144-A144, February 1, 2024. Introduction:CTP has increasingly been incorporated into the evaluation of all patients with suspected acute ischemic stroke (AIS), including those with minor symptoms. had AIS on CT/MRI.

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Stroke Strokes Thrombolysis Academic 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP31-ATMP31, February 1, 2024. Background:Despite advances in intravenous thrombolysis and endovascular thrombectomy, numerous acute ischemic stroke survivors continue to experience various disability levels. Both groups followed standard Stroke Guidelines for treatment.

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Stroke Strokes Thrombolysis Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP95-AWP95, February 1, 2024. Because of the need to provide care quickly, consent is often obtained remotely in acute ischemic stroke. Because of the need to provide care quickly, consent is often obtained remotely in acute ischemic stroke.

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Thrombolysis Stroke Strokes Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP71-AWP71, February 1, 2024. A simple mediation model with covariates NIHSS and average telestroke volume was used to determine if DTSR mediates the relationship between door to stroke alert and DTN. Prehospital stroke alert by EMS reduced DTSR by 6.99 and 238 (50.5%) were female.

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Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A97-A97, February 1, 2024. vs 19.6%, p=0.002) and a past-history of stroke/TIA (36% vs 25%, p<0.001) when compared to non-AC group. Intravenous thrombolysis was used much less commonly for AIS-despite-AC (10.5% Patients who had AIS-despite-AC were younger (76.8+11 11 vs 77.8+12,

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A1-A1, February 1, 2024. Background:Enrollment into hyperacute stroke trials may be constrained since candidates are usually not identified until they arrive in the emergency department. patients per month compared to 2.4 after intervention (12/2021 - 07/2023), 2.43, 95% CI: 1.48-4.10,

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