2024 and Sickle Cell Disease - Cardiovascular Update

AND017 Receives FDA Orphan Drug Designation for Sickle Cell Disease

HCPLive

OCTOBER 25, 2024

On October 25, 2024, Kind Pharmaceutical announced receipt of FDA Orphan Drug Designation for AND017 in the treatment of sickle cell disease.

Sickle Cell Disease

Hematology Month in Review: March 2024

HCPLive

APRIL 3, 2024

Our March 2024 month-in-review in hematology features updates to the anemia pipeline, the latest research in sickle cell disease, and the role of SGLT2 inhibition on hematologic outcomes.

Sickle Cell Disease

Sickle Cell Disease Research Outcomes

Updates, News in Sickle Cell Disease, with Steven Fein, MD

HCPLive

DECEMBER 17, 2024

Steven Fein, MD, discusses news and updates in sickle cell disease following ASH 2024.

Sickle Cell Disease

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

MORE WEBINARS

Hematology Month in Review: April 2024

HCPLive

MAY 2, 2024

Our April month in review for hematology breaks down the latest updates to the pipeline, mortality risk in people with sickle cell disease, and our newest multimedia offerings.

Sickle Cell Disease

Abstract TP147: Assessment of Inter-Rater Reliability of Fazekas Scoring on Magnetic Resonance Imaging in Patients With Sickle Cell Disease

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP147-ATP147, February 1, 2024. Background:White matter disease is a common phenomenon in patients with sickle cell disease, that has been linked to cognitive impairment. However, there is no standardized approach for quantification of the cerebral disease burden.

Sickle Cell Disease

Sickle Cell Disease Research Stroke Strokes

Abstract TMP7: Disruption of Blood Brain Barrier is Associated With Silent Cerebral Infarcts in Patients With Sickle Cell Disease

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP7-ATMP7, February 1, 2024. Background:Microvascular thromboinflammation is a major pathomechanism underlying vaso-occlusive crisis in patients with sickle cell disease (SCD), yet its role underlying the elevated stroke risk in SCD is unclear.

Sickle Cell Disease

Sickle Cell Disease Stroke Strokes

Abstract TMP12: Large Vessel Vasculopathy is Associated With Oxygen Metabolic Stress in Children and Young Adults With Sickle Cell Disease

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP12-ATMP12, February 1, 2024. Background:Large-vessel vasculopathy (LVV), such as moyamoya syndrome, increases stroke risk with sickle cell disease (SCD).

Sickle Cell Disease

Sickle Cell Disease Stenosis Circulation Stroke

Detection of Subclinical Cardiac Dysfunction in Patients with Sickle Cell Disease using Speckle Tracking Echocardiography

The American Journal of Cardiology

AUGUST 10, 2024

Publication date: Available online 10 August 2024 Source: The American Journal of Cardiology Author(s): Min-Jung Kim, Grace Lee, Gian Lima, Osama Mukarram, Samuel Crooks, Kristin Marshall, Agnes S.

Sickle Cell Disease

Lantheus Announces the FDA Approval of DEFINITY as Ultrasound Enhancing Agent for Use in Certain Pediatric Cardiovascular Patients

DAIC

MARCH 6, 2024

Food and Drug Adminstration (FDA) has approved DEFINITY (Perflutren Lipid Microsphere) as an ultrasound enhancing agent for use in pediatric patients with suboptimal echocardiograms, including those who have undergone heart transplant, or have Kawasaki disease or a congenital cardiovascular anomaly.

Pediatrics

Pediatrics Ultrasound Heart Transplant Echocardiogram

Abstract WP222: Basilar Artery Stenosis in Children With Moyamoya

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2024. Introduction:Moyamoya is a progressive cerebrovascular disease characterized by stenosis of the cerebral arteries in the anterior circulation and less often the posterior circulation.

Stenosis

Stenosis Sickle Cell Disease Cerebrovascular Disease Pediatrics

Abstract WP32: A Dissection of Spinal Cord Infarction: Cases With Rare Features and Innovative Treatments

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP32-AWP32, February 1, 2024. Spinal cord infarction (SCI) poses a unique set of diagnostic and therapeutic challenges to clinicians. One patient was also found eligible and treated with IV-thrombolysis.

Sickle Cell Disease

Sickle Cell Disease Innovation Thrombolysis Academic

Abstract WP218: Risk Factors for Cerebral Aneurysms in Sickle Cell Disease

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP218-AWP218, February 1, 2024. Introduction:Cerebral aneurysm frequency in sickle cell disease (SCD) is higher than in the general population. Specific risk factors explaining this difference have not been previously explored.

Sickle Cell Disease

Sickle Cell Disease Aneurysm Risk Factors Blood Pressure

Published Research

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)

Research

Research Coronary Artery Bypass Graft Aortic valve Congenital

AND017 Receives FDA Orphan Drug Designation for Sickle Cell Disease

Hematology Month in Review: March 2024

Updates, News in Sickle Cell Disease, with Steven Fein, MD

Webinars

Hematology Month in Review: April 2024

Abstract TP147: Assessment of Inter-Rater Reliability of Fazekas Scoring on Magnetic Resonance Imaging in Patients With Sickle Cell Disease

Abstract TMP7: Disruption of Blood Brain Barrier is Associated With Silent Cerebral Infarcts in Patients With Sickle Cell Disease

Abstract TMP12: Large Vessel Vasculopathy is Associated With Oxygen Metabolic Stress in Children and Young Adults With Sickle Cell Disease

Detection of Subclinical Cardiac Dysfunction in Patients with Sickle Cell Disease using Speckle Tracking Echocardiography

Lantheus Announces the FDA Approval of DEFINITY as Ultrasound Enhancing Agent for Use in Certain Pediatric Cardiovascular Patients

Abstract WP222: Basilar Artery Stenosis in Children With Moyamoya

Abstract WP32: A Dissection of Spinal Cord Infarction: Cases With Rare Features and Innovative Treatments

Abstract WP218: Risk Factors for Cerebral Aneurysms in Sickle Cell Disease

Published Research

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