DAIC

FEBRUARY 2, 2024

9-11, 2024. Image courtesy: Getty Images christine.book Fri, 02/02/2024 - 11:35 February 2, 2024 — The American College of Cardiology ’s Cardiac Oncology Conference, “ Advancing the Cardiovascular Care of the Oncology Patient ,” will be held in person at the Heart House in Washington, D.C., How to Structure?

Cardio Oncology 95

Cardio Oncology Cancer Pharmacology RN 95

Nature Reviews - Cardiology

FEBRUARY 18, 2024

Nature Reviews Cardiology, Published online: 19 February 2024; doi:10.1038/s41569-024-01000-6 Two studies indicate that a reduction in body mass index as a result of either bariatric surgery or pharmacological therapy is associated with a blood pressure-lowering effect.

Blood Pressure 55

Blood Pressure Pharmacology 55

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP312-ATP312, February 1, 2024. Traumatic brain injury (TBI) afflicts 70 million people worldwide annually and is the 3rd overall risk factor for developing Alzheimer's disease (AD), behind genetics and aging.

Pharmacology 40

Pharmacology Risk Factors Strokes Stroke 40

Journal of Cardiovascular Pharmacology

JUNE 24, 2024

A personalised management plan including rationalising medications, patient education, identification, and avoidance of triggers, as well as non-pharmacological therapies such as compression devices, dietary modifications, and postural aids, make the first steps. Copyright © 2024 The Author(s).

Pharmacology 40

Pharmacology Hypertension Education Article 40

Circulation

MARCH 17, 2024

Circulation, Volume 149, Issue 12 , Page e996-e996, March 19, 2024.

Pharmacology 45

Pharmacology Arrhythmia Circulation 45

The British Journal of Cardiology

AUGUST 14, 2024

Faculty member Affiliation Professor Amitava Banerjee Professor of Clinical Data Science, Institute of Health Informatics, University College London; Consultant Cardiologist, University College London Hospitals and Barts Health NHS Trust Professor Sir Mark Caulfield Professor of Clinical Pharmacology, Queen Mary Un.

Cardiovascular Disease 52

Cardiovascular Disease Patient Care Innovation Pharmacology 52

Journal of Cardiovascular Pharmacology

SEPTEMBER 5, 2024

Heparin, the most utilized anticoagulant, carries concerns for heparin-induced thrombocytopenia and possible resistance given its dependence on co-factors and circulating proteins to exert its pharmacologic effect. Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

Laboratory 40

Laboratory Thrombosis Pharmacology Pulmonary 40

DAIC

FEBRUARY 27, 2024

Getty Images milla1cf Tue, 02/27/2024 - 17:24 February 27, 2024 — Biosense Webster, Inc. , The study will compare the safety and efficacy of the Laminar LAAX System to commercially available left atrial appendage (LAA) closure devices, providing a potential non-pharmacologic alternative for eligible patients. 

Atrial Fibrillation 105

Atrial Fibrillation Innovation AFIB Pharmacology 105

DAIC

JUNE 7, 2024

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

Aortic valve 105

Aortic valve Aortic Heart Valves Pharmacology 105

DAIC

MAY 14, 2024

Getty Images milla1cf Tue, 05/14/2024 - 13:00 May 14, 2024 — One of the most common genetic heart diseases worldwide, hypertrophic cardiomyopathy (HCM) causes the walls of the left ventricle to become thick and stiff. The late breaking research was presented by principal investigator Martin S.

Cardiomyopathy 126

Cardiomyopathy Exercise Chest Pain Heart Failure 126

DAIC

JULY 10, 2024

Getty Images mtaschetta-millane Wed, 07/10/2024 - 08:51 July 10, 2024 — Reviva Pharmaceuticals Holdings, Inc. , Reviva believes that a full battery of regulatory compliant toxicology and safety pharmacology studies has been completed for brilaroxazine.

Pulmonary 111

Pulmonary Hypertension Pharmacology Biomarkers 111

Journal of Cardiovascular Pharmacology

JUNE 24, 2024

The present viewpoint succinctly illustrates the main features of SGLT2 inhibitors as a pharmacologic class, their ever expanding role as a cardiovascular medication, and the comparative effectiveness of different individual SGLT2 inhibitors, explicitly commenting on the recent data on empagliflozin in patients with acute myocardial infarction.

Myocardial Infarction 40

Myocardial Infarction Heart Failure Pharmacology Diabetes 40

The British Journal of Cardiology

AUGUST 21, 2024

In this historical review, we explore its journey from ancient wisdom to becoming a cornerstone of heart failure (HF) therapy, including discovery of its pharmacological properties and an appraisal of early clinical studies.

Atrial Fibrillation 52

Atrial Fibrillation Pharmacology Heart Failure 52

Journal of Cardiovascular Pharmacology

MAY 19, 2024

The adherence to pharmacological treatment was 99%.Additionally, The adherence to pharmacological treatment was 99%.Additionally, Copyright © 2024 Wolters Kluwer Health, Inc. During a mean follow-up of 664 ± 177 days, the incidence rate of major bleedings and of major cardiovascular events (MACE) was 0.8 Additionally, 13.4%

Peripheral Arterial Disease 40

Peripheral Arterial Disease Pharmacology Article 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP301-AWP301, February 1, 2024. We hypothesized that pharmacological inhibition of STAT3 activation in mice during the reperfusion phase after middle cerebral artery occlusion (MCAO) will lead to increased infarct size. Interestingly Stattic-treated mice had larger spleens (66.31 ± 5.40

Strokes 40

Strokes Stroke Pharmacology Ischemia 40

Journal of Cardiovascular Pharmacology

APRIL 1, 2024

Importantly, we found F2-induced activation of Nrf2 is SIRT1-dependent, as pharmacologically inhibiting SIRT1 by the specific inhibitor EX527 blocked Nrf2 activation. Importantly, we found F2-induced activation of Nrf2 is SIRT1-dependent, as pharmacologically inhibiting SIRT1 by the specific inhibitor EX527 blocked Nrf2 activation.

Ischemia 40

Ischemia Pharmacology Heart Disease Article 40

The British Journal of Cardiology

MAY 14, 2024

This review describes the physiological rationale behind FXI/FXIa inhibition and the pharmacological properties of existing FXI/FXIa inhibitors.

Thrombosis 52

Thrombosis Pharmacology Physiology Atrial Fibrillation 52

DAIC

APRIL 3, 2024

April 3, 2024 — In gearing up for its Annual Scientific Session, ACC.24, The “Pharmacology Program” will cover hot topics in cardiovascular medicine that are key issues that pharmacists, as well as other health care team members, face in managing complex patients. Notably, 2024 marks the 40th Anniversary of ACC/AHA Guidelines.

Education 105

Education Preserved Ejection Fraction Coronary Artery Disease Cardio Oncology 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP320-ATP320, February 1, 2024. We and others have shown that either genetic deficiency of C3aR or its pharmacological inhibition in rodents protects against ischemic brain injury. Background:The complement C3a receptor (C3aR) plays a prominent role in deleterious post-stroke neuroinflammation.

Strokes 40

Strokes Stroke Embolism Pharmacology 40

DAIC

JULY 25, 2024

mtaschetta-millane Thu, 07/25/2024 - 09:08 July 25, 2024 — BioCardia, Inc. , Despite guideline-directed therapies employing a wide range of pharmacologic, device, and surgical options, many patients deteriorate over time and develop advanced heart failure symptoms that cannot be effectively managed by existing medical therapies.

Heart Failure 111

Heart Failure Quality of Life CMS Reimbursement 111

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP17-ATP17, February 1, 2024. Inhibition of the SPAK-NKCC1 cascade by pharmacological inhibitor has therapeutic potential for VCID therapy.This research was supported by NIH R01 166199 Grant (M.I.H.B.). However, the molecular and cellular mechanisms underlying VCID are not well understood.

Dementia 40

Dementia Pharmacology Stenosis Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2024. There were pharmacological changes in 21.5% (n= 11) of the patients reviewed. Background:Stroke is a debilitating condition and patients with acute stroke usually stays about a week in the acute hospital.

Nursing 40

Nursing Hospital Outpatient Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP322-AWP322, February 1, 2024. In a subset of Hhcy rats, NVP-AAM077, a pharmacological inhibitor of GluN2A-NMDAR was injected intravenously at the onset of stroke. Hyperhomocysteinemia (Hhcy), a metabolic disorder is recognized as a risk factor for ischemic stroke.

Ischemia 40

Ischemia Pharmacology Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2024. Pharmacological inhibition of EZH2 improved cognitive outcomes in CAA mice, suggesting a possible therapeutic target. Introduction:Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid-β (Aβ) in the leptomeningeal and cortical vessels.

Dementia 40

Dementia Pharmacology Strokes Stroke 40

Cardiometabolic Health Congress

AUGUST 30, 2024

Pharmacological Interventions : Use of antihypertensive medications, lipid-lowering agents, and antidiabetic drugs. Key Areas for Evidence Based Cardiometabolic Care Essential areas for evidence-based strategies in cardiometabolic care include: Lifestyle Interventions : Effective management of diet, physical activity, and weight.

Cardiac Rehabilitation 52

Cardiac Rehabilitation Heart Failure Quality of Life Aortic 52

DAIC

APRIL 11, 2024

Optimal medical therapy for coronary artery disease includes lifestyle modifications and intensive pharmacologic interventions, according to the contemporary guideline directed medical therapy for secondary prevention. Half of the participants were randomly assigned to receive PCI plus medical therapy and half received medical therapy alone.

Plaque 111

Plaque Heart Attack Heart attacks Coronary Artery Disease 111

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP317-AWP317, February 1, 2024.

Strokes 40

Strokes Stroke Pharmacology 40

DAIC

MAY 9, 2024

Image courtesy: Getty Images christine.book Thu, 05/09/2024 - 15:33 May 9, 2024 — The American College of Cardiology ( ACC ) and the American Heart Association ( AHA ) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM).

Cardiomyopathy 52

Cardiomyopathy Pediatrics Quality of Life Sudden Cardiac Death 52

Cardiometabolic Health Congress

JULY 10, 2024

Bakris , an internationally recognized and influential nephrologist and hypertension expert, who passed away on June 15, 2024, at the age of 72. The entire CMHC and cardiometabolic community mourns the loss of Dr. George L.

Hypertension 52

Hypertension Education Blood Pressure Kidney Disease 52

DAIC

MAY 21, 2024

Multiple regression analyses examined the influence of guideline-based, non-pharmacological lifestyle-based digital coaching on outcomes adjusting for confounders. Retrospective evaluation explored the influence of app engagement on changes in BP, TC, LDL-C and weight. Of 102,475 participants, 49.1% were female.

Blood Pressure 52

Blood Pressure Cholesterol Risk Factors BMI 52

DAIC

FEBRUARY 29, 2024

Image courtesy: ACC christine.book Thu, 02/29/2024 - 11:22 February 29, 2024 — The American College of Cardiology ( ACC ) will soon be holding its ACC 73rd Annual Scientific Session & Expo , ACC.24 24 from April 6 - 8, 2024 in Atlanta, GA at the Georgia World Congress Center. The Guidelines Sessions at ACC.24

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

DAIC

MAY 16, 2024

Among those ages 65 and older, nearly 50% who underwent limb amputation died within one year after surgery, according to the 2024 Heart Disease and Stroke Statistics: A Report of U.S. Pharmacological and behavioral-based strategies often increase the smoking cessation rate in people with PAD, however, these strategies are underused.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Quality of Life Ischemia 105

Journal of Cardiovascular Pharmacology

AUGUST 1, 2024

Copyright © 2024 Wolters Kluwer Health, Inc. Despite the wide array of anti-thrombotic drugs available, these treatments frequently carry substantial risks, notably including bleeding complications. In this paper, we comment the findings reported by Liu et al. All rights reserved.

Cerebrovascular Disease 40

Cerebrovascular Disease Myocardial Infarction Thrombosis Strokes 40

Journal of Cardiovascular Pharmacology

SEPTEMBER 12, 2024

Copyright © 2024 Wolters Kluwer Health, Inc. These results demonstrate an important role of PPARγ as a negative regulator of IL-6 induced hepatic Lp(a) production and may represent a new therapeutic target for patients with inflammatory conditions characterized by elevated Lp(a). All rights reserved.

Risk Factors 40

Risk Factors 40

Journal of Cardiovascular Pharmacology

AUGUST 20, 2024

Copyright © 2024 Wolters Kluwer Health, Inc. SGLT2I users had a higher risk of ED than the non-SGLT2I users (adjusted HR = 1.55, 95% CI = 1.40-1.72). The likelihood of developing ED was higher in patients with SGLT2I use was found. All rights reserved.

Diabetes 40

Diabetes Risk Factors Article 40

DAIC

FEBRUARY 7, 2024

During the American Stroke Association’s International Stroke Conference 2024, ISC24, eleven scientists leading the way in stroke research will be recognized for their exceptional professional achievements. The world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health is being held Feb.

Strokes 105

Strokes Stroke Research Health Disparities 105

Journal of Cardiovascular Pharmacology

SEPTEMBER 12, 2024

Copyright © 2024 Wolters Kluwer Health, Inc. Therefore, we recapitulate here methodological issues evaluating potential value of the IKur as an antiarrhythmic target when investigated in animal models, in human atrial tissues and finally in atrial hiPSC-CM. All rights reserved.

Pharmacology 40

Pharmacology CMS Electrophysiology Physiology 40