Stroke Journal

JANUARY 30, 2025

A good clinical outcome (mRS 90day 2) was achieved by 61.4%. There were also no other complications.Conclusion:Rescue therapy in the form of prolonged low-dose thrombolysis seems to be an effective and safe alternative to therapeutic nihilism in ultra-early stroke recurrence. Improvement occurred in 70.5% of patients.

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Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP8-AWP8, February 1, 2024. Median time from the onset of visual change to thrombolysis was 6.0 [4.5-10.5] Introduction:Branch retinal artery occlusion (BRAO) results from the blood flow compromise in of the branches of the central retinal artery. VA improvement of ≥0.1

Thrombolysis 40

Thrombolysis Outcomes Hemorrhage Stroke 40

Stroke Journal

JANUARY 30, 2025

The effectiveness and safety of intravenous thrombolysis (IVT) for acute ischemic stroke in these cases, particularly those involving large vessel occlusions, are debated. We searched MEDLINE (OVID), EMBASE, web of Science, and SCOPUS from inception to 03/03/2024. Stroke, Volume 56, Issue Suppl_1 , Page AWP9-AWP9, February 1, 2025.

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Thrombolysis Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP202-AWP202, February 1, 2024. The role of adjunctive intravenous thrombolysis, such as intravenous tissue plasminogen activator (IVtPA), with MT remains unclear, especially for medium vessel occlusion (MeVO). Further research is needed to determine the optimal treatment approach for MeVO.

Thrombolysis 40

Thrombolysis Academic Hemorrhage Outcomes 40

The American Journal of Cardiology

DECEMBER 21, 2024

Publication date: Available online 20 December 2024 Source: The American Journal of Cardiology Author(s): Peiren Zhang, Bin Luo, Peilan Zhang, Xiaoqing Yu, Xiaoyue Long, Yuxuan Du, Haozhi Tian, Liwen Wang

Thrombolysis 40

Thrombolysis Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP179-AWP179, February 1, 2024. We defined two binary outcomes: (1) functional clinical outcome (modified Rankin Scale 0-2) and (2) early symptomatic intracerebral hemorrhage (sICH). 4.14, p=0.9502), but it was associated with a functional clinical outcome at 90 days (OR 3.39, 95% CI 1.11-10.43,

Stents 40

Stents Stent Thrombolysis Angioplasty 40

Stroke Journal

JANUARY 30, 2025

We studied the impact of intravenous thrombolysis (IVT) on the outcomes of EVT in those patients.Methods:We conducted a meta-analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist and the Cochrane Handbook of Systematic Reviews and Interventions.

Thrombolysis 40

Thrombolysis Hemorrhage Outcomes Stroke 40

Stroke Journal

JANUARY 30, 2025

Introduction:Current guidelines recommend 24-hours of high-intensity monitoring (HIM) for acute ischemic stroke patients post-intravenous thrombolysis (IVT) due to risk of bleeding complications including symptomatic intracranial hemorrhage (sICH).

Thrombolysis 40

Thrombolysis ICU Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT). Yet AIS survivors often experience a range of unstudied post-stroke complications which negatively affect patient reported outcomes.

Thrombolysis 40

Thrombolysis Stroke Strokes Quality of Life 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP213-ATP213, February 1, 2024. Background and Purpose:Although intra-arterial thrombolysis (IAT) is widely used as adjunct with mechanical thrombectomy in acute ischemic stroke patients, the patients who are likely to benefit are not known.

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Thrombolysis Stroke Strokes Stents 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP106-ATP106, February 1, 2024. min for English and non-English speakers, respectively, and differences were not statistically significant.Discussion:Previous studies have reported lower IVT use, longer DTN times and poorer clinical outcomes in patients who required an interpreter. min and 48.2

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Thrombolysis Document Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Previous evidence indicated that transcranial doppler (TCD) parameters were associated with functional outcome in large vessel occlusion stroke (LVOS) patients who undergo mechanical thrombectomy (MT). Patients without TCD studies, or with a poor temporal window were excluded.

Outcomes 40

Outcomes Thrombolysis Hypertension Stroke 40

Stroke Journal

JANUARY 30, 2025

Background:Early prediction of functional outcome after rtPA helps clinicians in prognostic conversations with stroke patients and their families. modified Rankin Scale (mRS) at one month, classified into good (mRS 2) and poor (mRS 5) outcomes was noted. 0.90) and poor outcomes (AUC=0.84, 95%CI:0.76-0.91). 0.90) outcomes.

Thrombolysis 40

Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP13-ATMP13, February 1, 2024. Introduction:Recent studies report similar outcomes with antiplatelet drugs and intravenous thrombolysis (IVT) in patients with minor nondisabling ischemic stroke.

Thrombolysis 40

Thrombolysis Stroke Strokes Academic 40

Stroke Journal

DECEMBER 21, 2023

Stroke, Volume 55, Issue 1 , Page 78-88, January 1, 2024. BACKGROUND:The association of COVID-19 with higher bleeding risk and worse outcomes in acute ischemic stroke (AIS) undergoing revascularization may be related to the presence of infection symptoms. 1.99]; aOR, 1.63 [95% CI, 1.14–2.32], 2.32], respectively). versus 85.6%;P<0.001),

COVID-19 40

COVID-19 Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A25-A25, February 1, 2024. Introduction:Intravenous thrombolysis (IVT) is efficacious treatment of acute ischemic stroke (AIS). Outcomes of interest were symptomatic intracranial hemorrhage (sICH), any ICH, serious systemic bleeding (SSB), and 90-day functional independence (mRS 0-2).

Thrombolysis 40

Thrombolysis Stroke Strokes Hemorrhage 40

Circulation: Cardiovascular Interventions

JANUARY 20, 2025

BACKGROUND:The aim of this study was to examine the impact of early versus delayed catheter-based therapies (CBTs) on clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE).METHODS:This Secondary outcomes included a composite of 30-day mortality, resuscitated cardiac arrest, and hemodynamic instability.

Embolism 40

Embolism Pulmonary Outcomes Cardiac Arrest 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A85-A85, February 1, 2024. Intravenous thrombolysis was administered in 55 patients (22.1%) while general anesthesia was used in 94/248 patients (37.9%). Favorable clinical outcome (90-day mRS 0-3) was achieved in 99/246 patients (40.2%), with mortality affecting 98/246 patients (39.8%).

Circulation 40

Circulation Outcomes Thrombolysis Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP182-AWP182, February 1, 2024. Background:Atrial fibrillation (AF) has been shown to be associated with better procedural outcomes in patients with anterior circulation large vessel occlusion (aLVO) undergoing endovascular therapy (EVT). In the NOAC group, 59.5%

Atrial Fibrillation 40

Atrial Fibrillation Outcomes Thrombolysis Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Demographic, clinical, radiographic, treatment and outcome data were collected via chart review and entered into a secure, HIPAA-compliant RedCAP database. Stroke presentation, treatment and outcomes are shown in Table 2. Intravenous thrombolysis was contraindicated in all MCS patients.

Stroke 40

Stroke Strokes Outcomes Pediatrics 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP195-ATP195, February 1, 2024. However, clinical outcomes remain similar. However, clinical outcomes remain similar. Patient outcomes at 3 months were assessed using modified Rankin Scale (mRS) scores, defining devastating outcomes as mRS 5-6.

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Outcomes Embolism Atrial Fibrillation Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP5-AWP5, February 1, 2024. While DM can reduce the effect of intravenous thrombolysis, metformin can have a positive outcome on AIS patients. The outcomes of stroke in diabetic patients receiving metformin is largely unexplored.

Diabetes 40

Diabetes Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. The primary outcome of interest was symptomatic intracranial hemorrhage (sICH) within 36 hours of tPA administration. A secondary outcome was modified Rankin Scale (mRS) at discharge. The pre-stroke antiplatelet therapy utilization frequencies were 56.9%

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Mobile Stroke Units (MSUs) are proven to shorten the time between stroke recognition and thrombolysis resulting to better patient outcomes and are deemed safe and cost-effective. There were 59 patients who received consultation and transport by the Stroke Ambulance of which 51 patients received thrombolysis.

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Stroke Strokes Thrombolysis Outcomes 40

DAIC

APRIL 7, 2024

milla1cf Sun, 04/07/2024 - 18:20 April 7, 2024 — An estimated 1 in 5 U.S. The study was designed so that neither patients nor their clinicians, the investigators or the experts who assessed patient outcomes knew which patients were receiving the drug and which the placebo until after the study was completed.

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Cholesterol Heart Attack Heart attacks Myocardial Infarction 116

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP92-ATMP92, February 1, 2024. Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-stroke dementia or cognitive impairment. Primary outcome was defined as favorable 90-day outcome (modified Rankin Scale (mRS) score 0-2).

Dementia 40

Dementia Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP126-AWP126, February 1, 2024. Introduction:The rapid advancement of artificial intelligence (AI) technologies holds promise for improving healthcare outcomes. These data support future studies expanding the use of AI technology to improve stroke outcomes.

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Stroke Strokes Outcomes Technology 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP186-AWP186, February 1, 2024. A higher burden of WMH is associated with poor functional outcomes after IVT. Overall, higher VSS grade was associated with a lower probability of achieving a good functional outcome, even after adjustments (Figure 1). of 476 patients without WMH (Table 1).Conclusions:Patients

Outcomes 40

Outcomes Stroke Strokes Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP10-AWP10, February 1, 2024. We aimed to examine the impact of dexmedetomidine on outcomes in patients with anterior circulation large vessel occlusion (acLVO) requiring neurocritical care after endovascular therapy (EVT).Methods:We Patients were categorized based on dexmedetomidine treatment.

Stroke 40

Stroke Strokes Outcomes Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP193-ATP193, February 1, 2024. Successful recanalization was defined as modified Thrombolysis in Cerebral Ischemia Score≥ 2b. The primary outcome was a 90-day modified Rankin Scale (mRS) of 0-3. The primary outcome was a 90-day modified Rankin Scale (mRS) of 0-3.

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Outcomes Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP93-AWMP93, February 1, 2024. Whether there are differences in time to intervention, and resultant patient outcomes, between such centers has not been thoroughly studied. It is forthcoming whether this difference impacts patient outcome measures.

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP6-AWP6, February 1, 2024. Background:Studies have demonstrated that the addition of alteplase for patients with tandem lesions who underwent mechanical thrombectomy and acute stenting was safe with improved outcomes. Favorable functional outcomes were seen in 80.0% of IV TNK vs 58.2%

Stents 40

Stents Stent Outcomes Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP104-ATP104, February 1, 2024. Introduction:Accurate outcome prognostication in acute ischemic stroke (AIS) informs essential medical decision-making for clinicians, patients, and families. independence) were classified as “good” outcomes and mRS 3-6 (non-independent) as “poor” outcomes.

Thrombolysis 40

Thrombolysis Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP127-ATP127, February 1, 2024. may be independently associated with good clinical outcomes in our cohort of AIS caused by MCA-DMVOs that were successfully treated with MT. is also associated with good clinical outcomes. years old [mean+-SD], 35 female). Conclusion:A CBV index ≥ 0.7

Outcomes 40

Outcomes Thrombolysis Biomarkers Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP22-AWP22, February 1, 2024. Introduction:Tenecteplase (TNK) is increasingly being utilized for IV thrombolysis in acute ischemic stroke, including for patients with large vessel occlusion (LVO) prior to transfer to an endovascular thrombectomy (EVT) capable center (TCC). TNK vs. 48.4%

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Outcomes Stroke Strokes Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A13-A13, February 1, 2024. Pre-transfer variables independently associated with clinical improvement were intravenous thrombolysis use, more distal occlusions, and lower serum glucose; variables associated with deterioration included more proximal occlusions and higher serum glucose.

Hospital 40

Hospital Outcomes Thrombolysis Document 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP37-ATMP37, February 1, 2024. The advancement of artificial intelligence (AI) technologies has potential to dramatically improve healthcare outcomes. Secondary outcomes included discharge Modified Rankin score (mRS) and hospital length of stay (LOS).Results:This

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Stroke Strokes Outcomes Technology 40