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After 30 years of disappointment, 2 randomized controlled trials investigating the effect of neurosurgical treatment on functional outcome in patients with intracerebral hemorrhage were published in 2024. In this critique article, we will discuss the main findings of these trials, their implications and future perspectives.
milla1cf Tue, 02/13/2024 - 17:52 February 13, 2024 — RapidAI , the global leader in developing Artificial Intelligence ( AI ) and clinical workflow solutions to combat life-threatening neurovascular, cardiac, and vascular diseases, today announced the publication of the TIMELESS trial in the New England Journal of Medicine (NEJM).
Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. The study was looking for improvement in functional outcomes at 90 days. 9 Phoenix, AZ. Adeoye, M.D.,
Introduction:Managing post-acute hemorrhagic stroke care is complex and necessitates close follow-up and coordination. Primary outcome evaluated variables contributing to attendance of a neuroscience appointment post-discharge and secondary outcome: examined 90-day all cause readmission using binomial logistic regressions.
Stroke, Volume 55, Issue Suppl_1 , Page AWP164-AWP164, February 1, 2024. Introduction:Patients who have had hemorrhagic strokes experience psychological and functional deficits after hospital discharge. Social Determinants of Health (SDoH) can also impact outcomes.
Stroke, Volume 55, Issue Suppl_1 , Page AWMP81-AWMP81, February 1, 2024. Introduction:Intracerebral Hemorrhage (ICH) leads to high rates of morbidity and mortality. Malnutrition is common in stroke patients and leads to worse outcomes. There was no association between BMI and ICH volume in patients with deep or lobar hemorrhage.
Stroke, Volume 55, Issue Suppl_1 , Page ATP34-ATP34, February 1, 2024. Comparative outcome analyses between pre-COVID (2016-2019) and COVID year (2020) were performed. Background:Hemorrhagic cerebrovascular manifestations are known to be associated with COVID-19. years with 72,650 (61.0%) being female.
Stroke, Volume 55, Issue Suppl_1 , Page AWP177-AWP177, February 1, 2024. Clinical characteristics, technical considerations associated with thrombectomy, severity and subtypes of HT (Heidelberg) and clinical outcomes were analyzed.Results:HT was adjudicated present in 70 out of 149 (47.0%) consecutive thrombectomy patients.
Image courtesy of El Camino Health milla1cf Thu, 06/13/2024 - 20:33 June 13, 2024 — Frederick St. Improving patient care and outcomes is what drives my commitment to helping find new solutions in the field. standard-of-care for managing postpartum hemorrhage, the JADA System.
the 2023 calendar year, our comprehensive stroke metric for hemorrhagic stroke scoring was at 64%, below the 'Get with the Guidelines' benchmark of 87%.To also developed a flow diagram to manage code strokes that bypass the ED, or do not present as a code stroke.Results:This performance improvement project began in March 2024.Current
Stroke, Volume 55, Issue Suppl_1 , Page ATMP76-ATMP76, February 1, 2024. Introduction:Intraventricular hemorrhage (IVH), a common complication of intracerebral hemorrhage (ICH), can occur with little or no associated ICH (mostly IVH, mIVH). mIVH is reported to have better outcomes than IVH associated with substantial ICH.
Stroke, Volume 55, Issue Suppl_1 , Page ATP167-ATP167, February 1, 2024. Introduction:Delirium associates with poor outcome after intracerebral hemorrhage (ICH), yet its incidence and contributing factors are poorly characterized. The median hemorrhage volume was 8.0 [1.6-24.7] Hispanic, 8.5% Asian, and 1.6%
Stroke, Volume 55, Issue Suppl_1 , Page AWMP74-AWMP74, February 1, 2024. Purpose:We previously reported that activated T cells accumulate in the perihematomal regions after Intracerebral hemorrhage (ICH) and aggravate hemorrhagic brain injury.
Stroke, Volume 55, Issue Suppl_1 , Page ATP244-ATP244, February 1, 2024. Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described. All tests were two-tailed and the error rate was set at 5%.Results:Among Results:Among 430 patients who met inclusion criteria, 22.3%
Stroke, Volume 55, Issue Suppl_1 , Page AWMP75-AWMP75, February 1, 2024. Background:Injury location is an established outcome predictor in intracerebral hemorrhage (ICH), with most studies focusing on outcomes relating to motor deficits.
Stroke, Volume 55, Issue Suppl_1 , Page ATP158-ATP158, February 1, 2024. Introduction:Viscoelastic hemostatic assays can detect coagulopathy relevant for intracerebral hemorrhage (ICH) patients at risk for hematoma expansion. However, it is unclear whether these assays associate with long term ICH outcomes.
Stroke, Volume 55, Issue 1 , Page 22-30, January 1, 2024. BACKGROUND:Cerebral cavernous malformation with symptomatic hemorrhage (SH) are targets for novel therapies. had at least one abnormal patient-reported outcome-measurement information system, Version 2.0 SH and asymptomatic change rates were adjudicated.
Stroke, Volume 55, Issue Suppl_1 , Page AWP209-AWP209, February 1, 2024. Background and Purpose:The role of surgical evacuation using craniotomy or endoscopic procedure in patients with intracerebral hemorrhage (ICH) associated with oral anticoagulants is not well described.
However, heterogeneity was observed in studies assessing outcomes such as intraventricular hemorrhage and Glasgow Coma Scale (GCS), indicating variability in populations or methodologies.Conclusion:One of the significant life-threatening condicions is ICH, and patients are associated with poor prognosis. 0.57 (p < 0.00001).
Background:Several studies have shown that tranexamic acid (TXA), an anti-fibrinolytic agent, may reduce hematoma expansion (HE) in intracerebral hemorrhage (ICH), but its therapeutic time window is unclear. The primary outcomes were HE, 24-hour hemorrhagic volume change, 90-day mortality and poor functional outcome.
Stroke, Volume 55, Issue Suppl_1 , Page AWP139-AWP139, February 1, 2024. Background:Cerebral vasospasm is a well-known complication after aneurysmal subarachnoid hemorrhage (aSAH) and occurs more commonly in younger patients. Worse outcome was defined as 3-month modified Rankin Scale 4-6.
Stroke, Volume 55, Issue Suppl_1 , Page ATP168-ATP168, February 1, 2024. Objective:Disorders of consciousness (DoC) are known to correlate with worse functional outcome after hemorrhagic stroke. The primary outcome was coma (GCS ≤ 8) at time of admission. The median [IQR] ICH volume was 9.3
Stroke, Volume 55, Issue Suppl_1 , Page AWP175-AWP175, February 1, 2024. Current guidelines for blood pressure (BP) management in patients with intracerebral hemorrhage (ICH) recommend acute lowering of systolic BP (SBP) to 140 mm Hg with a maintenance goal of 130 - 150 mm Hg. All ICH patients from 2018 through 2022 were included.
Stroke, Volume 55, Issue Suppl_1 , Page ATP279-ATP279, February 1, 2024. Whether atrial cardiopathy is associated with the risk of intracranial hemorrhage in acute ischemic stroke (AIS) remains uncertain. Our primary outcomes included any intracranial hemorrhage (ICH) and symptomatic ICH (sICH) during follow-up.
Stroke, Volume 55, Issue 1 , Page 50-58, January 1, 2024. BACKGROUND:The effect of marine omega-3 PUFAs on risk of stroke remains unclear.METHODS:We investigated the associations between circulating and tissue omega-3 PUFA levels and incident stroke (total, ischemic, and hemorrhagic) in 29 international prospective cohorts.
Stroke, Volume 55, Issue Suppl_1 , Page AWMP78-AWMP78, February 1, 2024. Recent landmark trials BEST-MSU and B_PROUD have proven that MSUs facilitate quicker thrombolysis times and improved functional outcomes at 90 days when compared to conventional emergency medical services (EMS) for acute ischemic stroke patients.
Introduction:Intracerebral hemorrhage (ICH) leads to the highest mortality among stroke patients. ICH expansion causes worse outcomes, especially with anticoagulant-associated ICH. In terms of functional outcome, the average improvement in discharge NIHSS score increased by 1.33
Stroke, Volume 55, Issue Suppl_1 , Page AWP130-AWP130, February 1, 2024. Hemorrhagic foci were identified using susceptibility-weighted imaging (SWI).Results:Among Results:Among 72 patients with RSSI, nearly half (n = 35, 48.6%) had hemorrhagic foci within the index RSSI lesions on follow-up SWI. versus 75.7%, P = 0.001).
Stroke, Volume 55, Issue Suppl_1 , Page ATMP73-ATMP73, February 1, 2024. Introduction:Pregnancy is a risk factor for subarachnoid hemorrhage (SAH). Demographics, comorbidities, and outcomes were compared between pregnant and not pregnant groups. Pregnant patients were identified. Variables with notable differences (>0.1
Stroke, Volume 55, Issue Suppl_1 , Page ATP186-ATP186, February 1, 2024. We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. The occurrence of hemorrhagic change was assessed on CT after MT.
Direct-to-angiography workflow relies on CBCT to exclude intracranial hemorrhage (ICH) to determine treatment eligibility for intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT). Systematic searches were last performed on April 1, 2024 in EMBASE, PubMed, Web-of-Science, Scopus, and CINAHL databases.
Stroke, Volume 55, Issue Suppl_1 , Page ATP156-ATP156, February 1, 2024. Introduction:Spontaneous intracerebral hemorrhages (ICH) remains the most devastating form of stroke. Conclusions:Our pilot study suggests that early SCUBA can efficiently evacuate deep hematoma with potential of improving functional outcome.
Stroke, Volume 55, Issue Suppl_1 , Page AWP274-AWP274, February 1, 2024. Background:Cerebral vasospasm in non-traumatic subarachnoid hemorrhage (SAH) is associated with a high rate of morbidity and mortality. Demographics, comorbidities, and outcomes were identified. ICD-10 I67.84) in non-traumatic SAH (ICD-9 430, ICD-10 I60).
Circulation, Volume 150, Issue Suppl_1 , Page A4147397-A4147397, November 12, 2024. Frailty and CVD are often interrelated, affecting disease and treatment outcomes. Frailty is a syndrome of physiological decline, characterized by marked vulnerability to adverse health outcomes. 10.82), GI hemorrhage (AOR = 2.03, 95% CI: 1.63-2.53),
Stroke, Volume 55, Issue Suppl_1 , Page A2-A2, February 1, 2024. Background:Mobile stroke units (MSUs) improve outcomes in thrombolytic-eligible ischemic stroke patients. Conclusion:In ICH patients, MSU management resulted in faster treatment and time to target SBP with similar clinical outcomes except higher late mortality.
Stroke, Volume 55, Issue Suppl_1 , Page A59-A59, February 1, 2024. We evaluated the risk of hemorrhage associated with newer, more potent antiplatelet medications and dual antiplatelet regimens among patients treated with intravenous tissue plasminogen activator (IV-tPA).Methods:Using no antiplatelet, 36.7% SAPT, and 6.4%
Stroke, Volume 55, Issue Suppl_1 , Page ATP242-ATP242, February 1, 2024. Introduction:Evaluating the prognosis of aSAH patients who may be at risk of poor outcomes using grading systems is one way to make a better decision on treatment for these patients. were all good at predicting patient prognosis on day 90th after ictus.
Stroke, Volume 55, Issue Suppl_1 , Page A114-A114, February 1, 2024. Introduction:Delayed cerebral ischemia (DCI) is a leading cause of morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH). The primary outcome was DCI, defined as an exclusionary change in GCS or new, none-treatment related infarcts on imaging.
Stroke: Vascular and Interventional Neurology, Volume 4, Issue 6 , November 1, 2024. The primary outcome was the improvement in knowledge from a precourse to postcourse test. The primary outcome was the improvement in knowledge from a precourse to postcourse test. The mean sum of critical actions completed by trainees was 9.75/14
Stroke, Volume 55, Issue Suppl_1 , Page A58-A58, February 1, 2024. Patients with E-LoF and comorbid COVID-19 had similar mortality rates with the 2019 cohort.Conclusion:Sustained efforts are needed to address socioeconomic disparities in healthcare access, quality, and outcomes during public health emergencies.
Stroke, Volume 55, Issue Suppl_1 , Page AWMP33-AWMP33, February 1, 2024. Background:The 2022 guidelines from the American Heart Association/American Stroke Association underscore the significance of coordinated multidisciplinary care and early discharge planning for spontaneous intracerebral hemorrhage (ICH) patients.
This has been associated with poor clinical outcomes. We aim to investigate the impact of anemia on clinical outcomes in patients with AF on oral anticoagulation. Methods We comprehensively searched PubMed, WOS, SCOPUS, EMBASE, and CENTRAL through March 2024 and conducted a prognostic systematic review and meta-analysis.
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