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Hiddo Heerspink, PhD, PharmD, joins the podcast during Kidney Week 2024 to discuss the SMART trial and the potential of semaglutide in people with kidneydisease without diabetes.
Sodium-glucose cotransporter type 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists are established glucose-lowering and weight-lowering agents used in the management of type 2 diabetes mellitus and obesity.
Gene-Based Analysis Predictive analytics is vital in reducing morbidity and mortality, with healthcare startups focusing on early risk prediction and disease detection. Much of heart disease is linked to conditions like diabetes, obesity, or chronic kidneydisease, and specific mutations in nucleic acids help identify them.
Photo: Business Wire milla1cf Thu, 01/18/2024 - 14:05 January 18, 2024 — Summa Therapeutics, LLC announced that the first-in-man injectable angioplasty procedures for patients with below-knee peripheral arterial disease (PAD) were performed successfully using its Finesse Injectable balloon catheter platform.
Stroke, Volume 55, Issue Suppl_1 , Page AWP278-AWP278, February 1, 2024. Background:The current AHA stroke prevention guidelines give Class 1 recommendations that patients with AIS and diabetes should receive glucose-lowering agents with cardiovascular benefit to reduce risk of MACE.
2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetickidneydisease. Clinicians and health care systems must be encouraged to make use of these treatments.”
Circulation, Volume 150, Issue Suppl_1 , Page A4137914-A4137914, November 12, 2024. This included an HbA1c>7.0%, age>50 with established CVD, heart failure, or chronic kidneydisease or an age>60 with at least one CVD risk factor. year follow-up time).Results:Among Results:Among 5002 (projected to 34.0
As a leader in the field of research-based cardiometabolic health education, CMHC is proud to present its CME education outcomes study at ADA (American Diabetes Association) 2024 Scientific Sessions, which offers its education-focused agenda to a wide number of healthcare practitioners from all areas of the U.S.
14, 2024 (GLOBE NEWSWIRE) — For nearly two decades, Dr. George L. Taking place October 17-19, 2024, at The Boston Park Plaza, MA, this is a must-attend event for healthcare professionals across all specialties and sectors. Bakris’ distinguished career as a leading educator and mentor. Boca Raton, FL, Aug.
Circulation, Volume 150, Issue Suppl_1 , Page A4141474-A4141474, November 12, 2024. Logistic regression was used to determine the association between 5-HTP levels and calcification severity, adjusting for age, gender, smoking status, chronic kidneydisease, hyperlipidemia, and diabetes. to 1.10); diabetes 1.24 (0.67
Circulation: Heart Failure, Volume 17, Issue 12 , Page e011629, December 1, 2024. More recently, the nonsteroidal MRA finerenone improved the HF outcomes of patients with HF with preserved ejection fraction, expanding the benefits previously seen among patients with diabetes and albuminuric chronic kidneydisease.
Circulation, Volume 150, Issue Suppl_1 , Page A4148106-A4148106, November 12, 2024. Owing to improved management, the life expectancy of patients with hemophilia has increased significantly and predisposes them to risk of cardiovascular diseases and thrombotic events. The hemophilia cohort was slightly older (63.2[16.8]
Circulation, Volume 150, Issue Suppl_1 , Page A4145609-A4145609, November 12, 2024. Introduction:Cannabis has been increasingly used as a recreational drug. Its cardiovascular effects depend on several factors, including the exact composition, route of administration, dose, and duration of use.
Circulation, Volume 150, Issue Suppl_1 , Page A4146863-A4146863, November 12, 2024. Introduction:The treatment of heart failure (HF) with hydralazine-isosorbide dinitrate (H-ISDN) in African Americans (AA) with New York Heart Association (NYHA) III-IV who remain symptomatic despite optimal medical therapy is a class Ia indication.
Stroke, Volume 55, Issue Suppl_1 , Page A52-A52, February 1, 2024. million by 2030 according to the Global Burden of Disease Study. Autoimmune diseases are increasingly associated with chronic conditions and may modify risks by altering underlying pathophysiology. to 2.26) and liver disease (OR 2.20, p < 0.01, CI 1.27
Circulation, Volume 150, Issue Suppl_1 , Page A4147960-A4147960, November 12, 2024. of patients had cardiovascular disease, 10.9% diabetes, and 15.5% chronic kidneydisease. The results were reported as the pooled results using risk ratio (RR) and a confidence interval (CI) of 95%.Results:The
A VSR is more likely to occur in patients who are older, female, hypertensive, have chronic kidneydisease, and have no prior history of smoking. It commonly occurs in the setting of a first myocardial infarction (MI) in the background of delayed or absent reperfusion therapy. Hammill SC. Edwards WD.
The Cardiorenal Forum’s recent 18 th Annual Scientific meeting looked at the latest updates in the failing heart and kidney. Dr Mohammad Wasef and Dr Sarah Birkhoelzer report its highlights.
2 Most are balancing multiple comorbidities, such as obesity, diabetes, hypertension and chronic kidneydisease (CKD). In fact, a 2024 report on heart failure trends and outcomes published in the Journal of Cardiac Failure showed that in patients with heart failure with preserved ejection fraction, 5-year mortality was 75.7%.
The first half of 2024 has ushered in a wave of transformative FDA approvals in cardiorenal metabolic health. Edwards EVOQUE Tricuspid Valve Replacement System (Approved: 02/01/2024) This system provides a novel approach to tricuspid valve replacement, potentially benefiting patients with tricuspid regurgitation without open-heart surgery.
The European Society of Cardiology (ESC) Congress 2024 (August 30 – September 2, 2024) has wrapped up, delivering groundbreaking insights into cardiovascular diseases and related conditions. Measuring eGFR and albuminuria is recommended for assessing kidneydisease in all hypertensive patients.
tim.hodson Wed, 09/11/2024 - 15:40 Sept. 11, 2024 — In the first national estimate in two decades, researchers at the University of California-San Francisco (UCSF) report that 10.5 million Americans have atrial fibrillation. million U.S. adults, according to new estimates from University of California-San Francisco. million U.S.
milla1cf Fri, 01/19/2024 - 10:55 January 19, 2024 — Orchestra BioMed , a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships, today announced the first patient was randomized in the BACKBEAT pivotal study in late December 2023. and Europe. billion adults worldwide.
It’s well known that heart disease is the U.S.’s s top cause of death, and our rising CVD rates have been widely covered, but a look back on some of the biggest stories of 2024 suggests that cardiovascular disease is about to become a much bigger problem. A JAMA analysis of 11k adults revealed that only 10.6%
mtaschetta-millane Sun, 04/07/2024 - 18:43 April 7. In a randomized study published in March 2024, patients with elevated blood pressure who were treated with zilebesiran alone saw their systolic blood pressure fall by up to 14.5 Approximately 1 in 4 patients had diabetes other than Type 1 in addition to high blood pressure.
SGLT-2 inhibitors were initially approved to treat Type 2 diabetes by lowering blood sugar. About 32% had Type 2 diabetes. This finding is completely consistent in both direction and magnitude with other studies of SGLT-2 inhibitors in populations with diabetes and chronic kidneydisease.”
Stroke, Volume 55, Issue Suppl_1 , Page AWP160-AWP160, February 1, 2024. Introduction:Chronic kidneydisease (CKD) is a risk factor for intracerebral hemorrhage (ICH) and for worse outcomes following ICH.
Finerenone is already approved to reduce cardiovascular and kidneydisease risks in patients with type 2 diabetes-associated CKD, but not for HF. Finerenone is a non-steroidal, selective mineralocorticoid receptor antagonist (nsMRA), blocking the mineralocorticoid receptor and its blood pressure effects.
Getty Images milla1cf Tue, 04/30/2024 - 12:56 April 30, 2024 — A multicenter study led by Vanderbilt University Medical Center ( VUMC ) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure , a leading cause of hospitalization and death.
SGLT-2 inhibitors were initially approved to treat Type 2 diabetes by lowering blood sugar. About 32% had Type 2 diabetes. This finding is completely consistent in both direction and magnitude with other studies of SGLT-2 inhibitors in populations with diabetes and chronic kidneydisease.”
Circulation, Volume 150, Issue Suppl_1 , Page A4139313-A4139313, November 12, 2024. Predictors of high-risk of advanced liver fibrosis, included older age, male sex, severe chronic kidneydisease, previous myocardial infarction, ischemic heart disease, and atrial fibrillation/flutter.
tim.hodson Wed, 09/11/2024 - 15:40 Sept. A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. million Americans have atrial fibrillation. million U.S. million U.S. The study appears Sept.
Short history from development to today’s price hikes Doctors Frederick Banting and Charles Best successfully isolated the hormone insulin just over 100 years ago, dramatically changing the lives of those with diabetes. million Americans with diabetes need to inject insulin to survive, according to the American Diabetes Association.
Bakris , an internationally recognized and influential nephrologist and hypertension expert, who passed away on June 15, 2024, at the age of 72. Bakris’s distinguished career in medicine spanned over four decades, marked by significant contributions to the fields of diabetickidneydisease, hypertension, and nephropathy progression.
To compare the efficacy of SGLT2 inhibitors among non-older and older patients we have searched PubMed, Cochrane Central, and Embase until February 2023 for randomized controlled trials (RCTs) investigating SGLT2 inhibitors in older (age 65 years) patients with diabetes mellitus, chronic kidneydisease, and chronic heart failure.
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).
Circulation: Cardiovascular Imaging, Volume 17, Issue 1 , Page e015858, January 1, 2024. BACKGROUND:Advanced chronic kidneydisease is associated with high cardiovascular risk, even after kidney transplant. years post-transplant. A minority had abnormal MPI (n=58, 15%). 2.66];P=0.33).
Circulation, Volume 150, Issue Suppl_1 , Page A4121215-A4121215, November 12, 2024. Background:Empagliflozin is a sodium glucose co-transporter 2 inhibitor that improves cardiovascular outcomes in patients with type 2 diabetes mellitus, chronic kidneydisease and heart failure.
Stroke, Volume 55, Issue Suppl_1 , Page AWP269-AWP269, February 1, 2024. Background:Research suggests that residing in a food desert (FD) area may negatively impact health by increasing cardiovascular risk factors.
Stroke, Volume 55, Issue Suppl_1 , Page ATP205-ATP205, February 1, 2024. Background and Purpose:Large vessel occlusion secondary to intracranial atherosclerotic disease (ICAD-LVO) has an estimated prevalence of 10-30%. women; mean age, 69.1 [SD, years; mean NIHSS score of 15.1 [SD, years; mean NIHSS score of 13.8 [SD,
11 Despite the link between inflammation and cardiovascular disease has been proven by extensive research, most physicians have focused on treating high-risk patients with lipid lowering therapies including statin therapy.1,12,13 Anti- inflammatory Therapy for Cardiovascular Disease. Elsevier; 2024:224-235. μ/L on 0.6
Early coronary disease and impaired heart function, with increased coronary vessel wall thickness, in asymptomatic, middle-aged individuals living with HIV has been reported in a new study published today in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America (RSNA). Gharib, M.D.
Regular assessment of eGFR and UACR, particularly in high-risk populations such as those with diabetes or hypertension, provides crucial insights into patient health. Updated guidelines recommend using these markers to guide decisions on therapy, including statin use in patients with mildly reduced kidney function.
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