Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.

Stenosis 74

Stenosis Thrombosis Dementia Embolism 74

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP13-AWMP13, February 1, 2024. Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association.

Dementia 40

Dementia Atherosclerosis Risk Factors Stroke 40

DAIC

SEPTEMBER 11, 2024

tim.hodson Wed, 09/11/2024 - 15:40 Sept. 11, 2024 — In the first national estimate in two decades, researchers at the University of California-San Francisco (UCSF) report that 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke. million Americans have atrial fibrillation. million U.S.

Atrial Fibrillation 92

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 92

Dr. Paddy Barrett

OCTOBER 11, 2024

Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. 2024 Jun 21. Obstructive Sleep Apnea (OSA). N Engl J Med.

Obesity 79

Obesity Cancer Dementia Coronary Artery Disease 79

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP298-ATP298, February 1, 2025. Background:Post stroke depression (PSD) affects over 33% of stroke survivors with the highest incidence occurring in the first year after stroke. Predictors of PSD include stroke severity, cognitive impairment, age, and physical disability.

Hospital 40

Hospital Stroke Strokes Hemorrhage 40

Stroke Journal

AUGUST 25, 2024

Stroke, Volume 55, Issue 9 , Page e265-e265, September 1, 2024.

Dementia 40

Dementia Exercise Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.

Stroke 40

Stroke Strokes Atherosclerosis Hemorrhage 40

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page 788-790, April 1, 2024.

Dementia 40

Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP22-AWMP22, February 1, 2024. Background:Mild manifestations of individual cerebral small vessel disease (CSVD) markers are common and may not denote increased risk, but high CSVD burden identifies individuals at increased risk of stroke and dementia. years (Q1-Q3: 5.1-12.5)

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP238-ATP238, February 1, 2024. Introduction:Stroke and transient ischemic attack (TIA) increase risk for cognitive impairment and dementia. Both subjects with stroke and subjects with TIA had increased serum PDGFRβ compared to those without history of CVA (6608.4 pg/mL and 5337.0

Stroke 40

Stroke Strokes Dementia Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP320-AWP320, February 1, 2024. Diabetes doubles the risk of VCID but the underlying reasons remain unclear.

Dementia 40

Dementia Diabetes Cholesterol Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP251-ATP251, February 1, 2024. Objective:Evidence has shown that obstructive sleep apnea (OSA) is associated with the development of stroke. However, there is limited data on how OSA can influence the development and severity of post stroke complications.

Stroke 40

Stroke Strokes Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Stroke might narrow the gap in executive function between stroke survivors with higher and lower education.

Education 40

Education Stroke Strokes Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP298-ATP298, February 1, 2024. Improvements in acute stroke treatment, including endovascular thrombectomy and critical care management, have increased survival rates after stroke. Depressive-like behavior persisted for 6 months post-stroke (PS) (p= <0.0001).

Stroke 40

Stroke Strokes Critical Care Management Critical Care 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP57-AWMP57, February 1, 2024. Introduction:Post-stroke delirium is common and leads to worse short- and long-term outcomes with higher 28-day modified Rankin Score (mRS), longer length of hospitalization, and increased odds of discharge to a nursing home, development of dementia, and death.

Stroke 40

Stroke Strokes Dementia Nursing 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A37-A37, February 1, 2024. The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers to take action to reduce the risk of stroke and dementia by motivating lifestyle changes (Fig 1).

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 324-334, February 1, 2024. Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. This review focuses on randomized secondary prevention trials involving antithrombotic therapy, endovascular treatment, open surgical therapy, and remote ischemic conditioning.

Stenosis 40

Stenosis Dementia Research Stroke 40

Cardiometabolic Health Congress

APRIL 12, 2024

80% of heart attacks and strokes linked to CVD are preventable with optimal risk factor management. New Addition to the Clinical Toolkit On March 22, 2024, the US FDA approved broad new label expansions for Esperion’s NEXLETOL® (bempedoic acid) Tablets and NEXLIZET® (bempedoic acid and ezetimibe) Tablets.

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart attacks Heart Attack 64

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page 801-811, April 1, 2024. Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins.

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP21-AWMP21, February 1, 2024. We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The outcome of interest was a composite of stroke, dementia, or LLD.

Outcomes 40

Outcomes Dementia Blood Pressure Public Health 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A69-A69, February 1, 2024. BHe was a composite of stroke, dementia and late-life depression. These results indicate that more nuanced strategies for ascertaining biological age are needed in stroke research and point to epigenetic clocks as a promising tool for this purpose.

Dementia 40

Dementia Stroke Strokes Outcomes 40

DAIC

SEPTEMBER 11, 2024

tim.hodson Wed, 09/11/2024 - 15:40 Sept. Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke.

Atrial Fibrillation 52

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Our outcome was a composite of stroke, TIA or MI.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Diet 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP70-AWMP70, February 1, 2024. Exposure to Fontan circulation may be associated with early onset of cerebral SVD, suggesting increased long term risk of stroke and dementia.

Congenital Heart Disease 40

Congenital Heart Disease Congenital Heart Disease Physiology 40

Journal of the American Heart Association

DECEMBER 14, 2024

Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. During 2year followup, BACE1 activity was independently related to dementia conversion (odds ratio, 17.72;P=0.001) Plasma BACE1 activity was negatively associated with hippocampal volume (coefficient 2.40,P<0.001),

Dementia 40

Dementia Biomarkers Hemorrhage Hypertension 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A17-A17, February 1, 2024. COVID-19 doubles the risk for acute ischemic stroke in patients with cardiovascular disorders, yet, the molecular mechanisms are unclear and remain unresolved medical challenges. Cerebral blood flow was measured using a Laser speckle imager.

COVID-19 40

COVID-19 Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2024. CAA may lead to dementia and stroke; however effective options currently are very limited to treat or halt CAA progression.

Pharmacology 40

Pharmacology Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP35-ATP35, February 1, 2024. Background:White matter hyperintensities (WMH) are associated with risk of dementia and stroke, so are an important therapeutic target for clinical trials.

Dementia 40

Dementia Atherosclerosis Diabetes Hypertension 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP23-ATP23, February 1, 2024. Introduction:The vascular contribution to Alzheimer’s disease (AD) and AD-related dementias is increasingly recognized.

Plaque 40

Plaque Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP17-ATP17, February 1, 2024. Background:Blood-brain barrier (BBB) breakdown, reactive astrogliosis, and myelin losses are the key features of vascular contributions to cognitive impairment and dementia (VCID).

Pharmacology 40

Pharmacology Dementia Stenosis Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP20-AWMP20, February 1, 2024. Introduction:Early identification of white matter hyperintensity-related cognitive impairment (WMH-CI) through normal MRI images is of great significance for early clinical intervention to reduce the occurrence of dementia.

Dementia 40

Dementia Biomarkers Hospital Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP6-ATMP6, February 1, 2024. Background:Anecdotal cases of rapidly progressing dementia in patients with dural arteriovenous fistulas (dAVFs) and cortical venous drainage have been reported in small series.

Outcomes 40

Outcomes Dementia Hypertension Stenosis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP308-AWP308, February 1, 2024. Introduction:Respiratory disorders, including sleep apnea, are an independent risk factor for the development of cognitive dysfunction and dementia. Disordered breathing occurs frequently in patients with AD (Alzheimer’s Disease).

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP32-AWMP32, February 1, 2024. Background:Cerebrovascular disease is a common cause of vascular cognitive impairment (VCI) and may progress to vascular dementia at a relatively fast rate.

Outpatient 40

Outpatient Dementia Outcomes Stroke 40

DAIC

FEBRUARY 7, 2024

During the American Stroke Association’s International Stroke Conference 2024, ISC24, eleven scientists leading the way in stroke research will be recognized for their exceptional professional achievements. Sacco Outstanding Stroke Research Mentor Award, which honors Ralph L. 7-9 in Phoenix, AZ. Sacco, M.D.,

Stroke 105

Stroke Strokes Research Health Disparities 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A67-A67, February 1, 2024. Background:People with acute stroke are at high risk of dementia. The rate of dementia per 100 person-years was highest after acute stroke compared to the general population (3.40 years (max 20y). years (max 20y).

Dementia 40

Dementia Stroke Strokes Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2024. Methods:To assess its validity as associated with incidence of dementia and stroke, the BCS was derived from the UK Biobank (UKB) baseline evaluation (2006-2010) for participants aged 40-69. 0.60], aged 50-59: HR: 0.68 [95%CI: 0.58-0.80],

Dementia 40

Dementia Stroke Strokes Research 40