Medical Xpress - Cardiology

FEBRUARY 1, 2024

Having a stroke may significantly increase the risk of developing dementia. The risk of dementia was the highest in the first year after a stroke and remained elevated over a period of 20 years, according to preliminary research presented at the American Stroke Association's International Stroke Conference 2024, held in Phoenix, Feb.

Dementia 40

Dementia Research Strokes Stroke 40

Dr. Paddy Barrett

NOVEMBER 1, 2024

Dementia: 64% reduction in risk. British Journal of Sports Medicine 2024; 58: 556-566. Death from any cause: 53% reduction in risk. Death from heart disease: 51% reduction in risk. Cancer deaths: 43% reduction in risk. High Blood Pressure: 37% reduction in risk. Heart Failure: 69% reduction in risk. Depression: 39% reduction in risk.

Exercise 120

Exercise Heart Disease Quality of Life Blood Pressure 120

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP22-ATP22, February 1, 2024. Background:The increased risk of dementia after delirium and infection might be influenced by cerebral small vessel disease-SVD. Dementia was diagnosed using clinical/cognitive assessment, medical records and death certificates. vs. 3.41,1.91-6.09,

Dementia 40

Dementia Certification Strokes Stroke 40

Dr. Paddy Barrett

FEBRUARY 21, 2025

Recent research suggested that the weight loss market was estimated to be worth $224 billion annually in 2021 and is estimated to exceed $400 billion by 2024 1. Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role.

Obesity 77

Obesity Diabetes Cardiovascular Disease Chronic Disease 77

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP16-AWMP16, February 1, 2024. Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. Over a median follow-up time of 6.4 years (Q1-Q3: 4.6-11.3),

Dementia 40

Dementia Risk Factors Education Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP13-AWMP13, February 1, 2024. Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association. years) with ongoing surveillance.

Dementia 40

Dementia Atherosclerosis Risk Factors Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP92-ATMP92, February 1, 2024. Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-stroke dementia or cognitive impairment. EVT in dementia patients in one study found only increased odds of ICH (adjusted OR 1.57

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Dementia Outcomes Strokes Stroke 40

DAIC

MAY 16, 2024

Getty Images milla1cf Thu, 05/16/2024 - 15:37 May 16, 2024 — People were more likely to develop a type of treatment-resistant hypertension when they experienced adverse effects of economic and social conditions that influence individual and group differences in health status, known as social determinants of health.

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Hypertension Blood Pressure Health Disparities Heart Attack 105

Dr. Paddy Barrett

OCTOBER 11, 2024

Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. 2024 Jun 21. Obstructive Sleep Apnea (OSA). N Engl J Med.

Obesity 79

Obesity Cancer Dementia Coronary Artery Disease 79

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP208-ATP208, February 1, 2024. Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. PED was defined as any type of dementia that was present prior to the index stroke. women), 86 (17.4%) had PED.

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Dementia Strokes Stroke Outcomes 40

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. The further along the line of insulin resistance you sit, the higher your risk of all the leading causes of death, including heart disease, dementia and many cancers 5. 2024 Jun 21:e033997.

Risk Factors 105

Risk Factors Heart Disease Dementia Diabetes 105

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP320-AWP320, February 1, 2024. Diabetes doubles the risk of VCID but the underlying reasons remain unclear.

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Dementia Diabetes Cholesterol Stroke 40

DAIC

SEPTEMBER 11, 2024

tim.hodson Wed, 09/11/2024 - 15:40 Sept. 11, 2024 — In the first national estimate in two decades, researchers at the University of California-San Francisco (UCSF) report that 10.5 million Americans have atrial fibrillation. million U.S. adults, according to new estimates from University of California-San Francisco.

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Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 92

Stroke Journal

AUGUST 25, 2024

Stroke, Volume 55, Issue 9 , Page e265-e265, September 1, 2024.

Dementia 40

Dementia Exercise Strokes Stroke 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide.

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Stenosis Thrombosis Dementia Embolism 74

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page 788-790, April 1, 2024.

Dementia 40

Dementia Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A37-A37, February 1, 2024. The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers to take action to reduce the risk of stroke and dementia by motivating lifestyle changes (Fig 1).

Dementia 40

Dementia Strokes Stroke Risk Factors 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 324-334, February 1, 2024. Its association with silent cerebral infarcts and its contribution to cognitive impairment and dementia emphasize the critical need for disease prevention and effective management strategies.

Stenosis 40

Stenosis Dementia Research Strokes 40

Cardiometabolic Health Congress

APRIL 12, 2024

New Addition to the Clinical Toolkit On March 22, 2024, the US FDA approved broad new label expansions for Esperion’s NEXLETOL® (bempedoic acid) Tablets and NEXLIZET® (bempedoic acid and ezetimibe) Tablets. Esperion expects the European Medicines Agency to give a final decision in the second quarter of 2024.

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart Attack Heart attacks 64

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4136812-A4136812, November 12, 2024. Background:Cognitive decline and dementia are significant global health concerns, with hypertension being a major risk factor. Increasingly, the elderly population is receiving pacemakers, and the pacing rates are set as low as 50bpm.

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Pacemaker Blood Pressure Dementia Risk Factors 40

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page 801-811, April 1, 2024. Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins.

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

The British Journal of Cardiology

JUNE 11, 2024

p=0.004) and more likely to have dementia (27.3% Adjusting for age, frailty and dementia, VVI pacing was associated with an increased risk of all-cause mortality (adjusted hazard ratio [HR] 2.1, vs. 50.7% ± 10.1, p=0.71), but were more frail (Rockwood scale 5.2 ± 1.8 vs. 4.3 ± 1.1, vs. 8.9%, p=0.011). vs. 17.5 ± 2.6 vs. 71.9 ± 8.6

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Pacemaker Dementia Physiology Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP238-ATP238, February 1, 2024. Introduction:Stroke and transient ischemic attack (TIA) increase risk for cognitive impairment and dementia. Without a lasting infarction, the cause of cognitive decline after TIA remains unknown.

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Strokes Stroke Dementia Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP22-AWMP22, February 1, 2024. Background:Mild manifestations of individual cerebral small vessel disease (CSVD) markers are common and may not denote increased risk, but high CSVD burden identifies individuals at increased risk of stroke and dementia.

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Strokes Stroke Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP21-AWMP21, February 1, 2024. We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The outcome of interest was a composite of stroke, dementia, or LLD.

Outcomes 40

Outcomes Dementia Blood Pressure Public Health 40

Journal of the American Heart Association

JANUARY 16, 2024

Journal of the American Heart Association, Volume 13, Issue 2 , January 16, 2024. As a neurodegenerative condition with insidious onset, Alzheimer disease and other dementias (AD/D) represent a key target for advances in monitoring disease symptoms.

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Research Technology Dementia 45

Journal of the American Heart Association

DECEMBER 14, 2024

Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. During 2year followup, BACE1 activity was independently related to dementia conversion (odds ratio, 17.72;P=0.001) Plasma BACE1 activity was negatively associated with hippocampal volume (coefficient 2.40,P<0.001),

Dementia 40

Dementia Biomarkers Hemorrhage Hypertension 40

Physiologically Speaking

AUGUST 23, 2024

Cognitive decline, including Alzheimer’s disease and dementia, is one of the largest causes of death and disability around the world (and all data indicate the rates are rising). 2024 Aug 27;121(35):e2402813121. Epub 2024 Aug 19. When our mind fails, our body follows. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.2402813121.

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Physiology Exercise Laboratory Dementia 122

Stroke Journal

JANUARY 30, 2025

This study evaluated antidepressant prescribing patterns at hospital discharge in acute AIS and hemorrhagic (ICH) stroke patients.Methods:We retrospectively examined prospectively collected data from an IRB-approved stroke registry at two academic Comprehensive Stroke Centers (CSC) between 1/1/2013 and 6/30/2024.

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Hospital Strokes Stroke Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP70-AWMP70, February 1, 2024. Exposure to Fontan circulation may be associated with early onset of cerebral SVD, suggesting increased long term risk of stroke and dementia.

Congenital Heart Disease 40

Congenital Heart Disease Congenital Heart Disease Physiology 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear.

Strokes 40

Strokes Stroke Atherosclerosis Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP251-ATP251, February 1, 2024. mild cognitive impairment, dementia, insomnia, fatigue, sleep quality, post-stroke depression, anxiety, recurrent strokes) compared to those stroke patients who do not have OSA (RR=1.05, 95% CI 0.97 to 1.13).

Strokes 40

Strokes Stroke Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP23-ATP23, February 1, 2024. Introduction:The vascular contribution to Alzheimer’s disease (AD) and AD-related dementias is increasingly recognized.

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Plaque Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP17-ATP17, February 1, 2024. Background:Blood-brain barrier (BBB) breakdown, reactive astrogliosis, and myelin losses are the key features of vascular contributions to cognitive impairment and dementia (VCID).

Pharmacology 40

Pharmacology Dementia Stenosis Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Repeated cognitive tests were administered in person or by telephone by trained cohort staff.

Education 40

Education Strokes Stroke Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A69-A69, February 1, 2024. BHe was a composite of stroke, dementia and late-life depression. Introduction:It is increasingly recognized that chronological age provides an incomplete assessment of true biological age.

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Dementia Strokes Stroke Outcomes 40

Journal of the American Heart Association

JANUARY 16, 2024

Journal of the American Heart Association, Volume 13, Issue 2 , January 16, 2024. BackgroundSmartphone‐based cognitive assessments have emerged as promising tools, bridging gaps in accessibility and reducing bias in Alzheimer disease and related dementia research.

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Dementia Research 40