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Circulation, Volume 150, Issue Suppl_1 , Page A4120743-A4120743, November 12, 2024. However, the most recurrent cardiac complication in RASopathies is pulmonary valve stenosis (PVS). Backgound:The RASopathies are developmental syndromes resulting from variants in the RAS/mitogen-activated protein (MAPK) cascade.
Circulation, Volume 150, Issue Suppl_1 , Page A4143390-A4143390, November 12, 2024. Introduction:Obesity is rising in prevalence worldwide and co-exists in patients with group 1 pulmonary hypertension (PH). Despite having group 1 PH, pulmonary capillary wedge pressure (PCWP) was higher with obesity (13.8 ± 6.3 vs 9.4 ± 7.7
Circulation, Volume 150, Issue Suppl_1 , Page A4142839-A4142839, November 12, 2024. Introduction:Inflammation is a key driver in the development of pulmonary arterial hypertension (PAH). The pulmonary vasculature was evaluated histologically. of which are fungi.
Circulation, Volume 150, Issue Suppl_1 , Page A4146445-A4146445, November 12, 2024. CD206+Macrophages were accumulated in the pulmonary vessel adventitia of idiopathic PAH (IPAH) patients as well asEgln1Tie2Cremice. RVSP and RV/(LV+S) ratio were measured.
Circulation, Volume 150, Issue Suppl_1 , Page A4145487-A4145487, November 12, 2024. reported several cases in which right lower pulmonary vein (RLPV) thrombi extended into the left atrium (LA). Thrombi are difficult to visualize directly and are recognized as lacking in pulmonary vein blood flow.
Circulation, Volume 150, Issue Suppl_1 , Page A4122350-A4122350, November 12, 2024. Pulmonary vein thrombi (PVTs) are common and are underestimated. Background:Retrieved thrombus studies have shown that retrieved thrombi have calcifications, indicating that the thrombi are old. In 2022, we reported that 98.6% from 50 y.o.
Circulation, Volume 150, Issue Suppl_1 , Page A4141118-A4141118, November 12, 2024. Metabolic abnormalities play a crucial role in the pathophysiological process of pulmonary vascular remodeling. ng/ml; idiopathic pulmonary arterial hypertension group: 5.28 ± 0.77
Circulation, Volume 150, Issue Suppl_1 , Page A4144785-A4144785, November 12, 2024. Background:Acquired mitochondrial dysfunction is one of the characteristics of pulmonary arterial hypertension (PAH). Single-cell analysis showed that ARMCX3 was highly expressed in pulmonary vascular smooth muscle cells and endothelial cells.
Circulation, Volume 150, Issue Suppl_1 , Page A4136694-A4136694, November 12, 2024. However, retrograde arterial perfusion from the femoral artery can increase left ventricular (LV) afterload, resulting in LV distention which may hamper myocardial recovery and worsen pulmonary congestion. 3.65]; p<0.0001).
Circulation, Volume 150, Issue Suppl_1 , Page A4140065-A4140065, November 12, 2024. Methods:This study was a multicenter retrospective analysis involving consecutive patients who underwent intentional TPVR between May 27, 2014, and September 14, 2023.
Circulation, Volume 150, Issue Suppl_1 , Page A4117657-A4117657, November 12, 2024. Background:Primary pulmonary arterial hypertension (PAH) is a disease affecting young subjects. It has very poor prognosis and optimal treatment is not available.
Circulation, Volume 150, Issue Suppl_1 , Page A4144822-A4144822, November 12, 2024. Multivariable Cox regression analyses were constructed to assess the relationship between AG and short-term outcomes in sepsis patients complicated by PH.Results:2012 sepsis patients with pulmonary hypertension were included.
Circulation, Volume 150, Issue Suppl_1 , Page A4143405-A4143405, November 12, 2024. PH was defined as pulmonary artery (PA) mean pressure >20 mmHg, and PH was classified as isolated precapillary PH and combined pre/postcapillary PH.Results:Of 99 COA patients that underwent RHC, 57 (58%) had PH.
Circulation: Cardiovascular Interventions, Volume 18, Issue 1 , Page e014499, January 1, 2025. BACKGROUND:The aim of this study was to examine the impact of early versus delayed catheter-based therapies (CBTs) on clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE).METHODS:This
Circulation, Volume 150, Issue Suppl_1 , Page A4147910-A4147910, November 12, 2024. Animal studies have shown that mice with TBX1 gene mutations have smaller left pulmonary arteries compared to wild type mice, defined by a reduced left pulmonary artery (LPA) to right pulmonary artery (RPA) ratio.
In other words: 1) infarct of the LAD territory (much of which could be old) and 2) inferior-posterior-lateral infarct. == MY Comment , by K EN G RAUER, MD ( 9/27 /2024 ): == I found today's case insightful for a number of reasons. See Discussion in the June 29, 2024 post of Dr. Smith' ECG Blog ). But because Dr.
Circulation, Volume 150, Issue Suppl_1 , Page A4135252-A4135252, November 12, 2024. Background:Pulmonary hypertension (PH) is a major contributor to cardiovascular disease-related morbidity and mortality.
Patients in the study will be randomized to undergo pulmonary vein isolation (PVI) and left atrial posterior wall ablation using the FARAPULSE PFA System, or receive AAD treatment, and followed for three years. Food and Drug Administration approval of the FARAPULSE PFA System in the first quarter of 2024. Circulation.
Circulation: Cardiovascular Interventions, Volume 17, Issue 12 , Page e013964, December 1, 2024. The strategy for pulmonary vein protection was correctly identified by interventionalist 1 and 2 in 9/12 and 8/12 cases, respectively.
Circulation, Volume 150, Issue Suppl_1 , Page A4131838-A4131838, November 12, 2024. CT Abdomen and Pelvis showed an enhancing heterogenous lesion at the left superior renal pole, left adrenal gland lesion, and a pulmonary artery filling defect. Based on this, the highest differential was a clot-in-transit.
BackgroundThis study aimed to assess the scientific results and activities of premature beats research from a global perspective.MethodsPublications related to premature beats published between 2003 and 2024 were identified and selected from the Web of Science core collection. The most cited references come from the journal named Circulation.
Circulation, Volume 150, Issue Suppl_1 , Page A4140664-A4140664, November 12, 2024. A cardiac gated CT detailed the pulmonary vein structure and incidentally revealed bilateral cystic lung changes, leading to a pulmonology referral. These enlargements were new compared with imaging one year prior. He was loaded with amiodarone.
Circulation, Volume 150, Issue Suppl_1 , Page A4142484-A4142484, November 12, 2024. Background:Pulmonary arterial hypertension (PAH) is characterized by an elevation in pulmonary vascular resistance and arterial pressure, culminating in right ventricular failure and mortality.
milla1cf Fri, 02/02/2024 - 17:02 February 2, 2024 — Biosense Webster, Inc. , The primary endpoint of the analysis was incidence of procedure – or device-related primary adverse events (PAEs) within seven to ninety days of the ablation procedure; the secondary endpoint was the rate of acute pulmonary vein (PV) isolation.1
Circulation, Volume 150, Issue Suppl_1 , Page A4142231-A4142231, November 12, 2024. Methods:The descriptive, cross-sectional study was conducted in patients with STEMI with a confirmed diagnosis and percutaneous coronary angiography at 108 Military Central Hospital from April 2023 to April 2024. The cut-off point was 14.9
Abstract: Extracorporeal membrane oxygenation (ECMO) is a mechanical support treatment modality utilized in patients with refractory cardiac and/or pulmonary failure. Extracorporeal membrane oxygenation (ECMO) is a mechanical support treatment modality utilized in patients with refractory cardiac and/or pulmonary failure.
Circulation, Volume 150, Issue Suppl_1 , Page A4135095-A4135095, November 12, 2024. Background:While anticoagulation is crucial for atrial fibrillation (AF) patients to prevent ischemic events, those with thrombocytopenia have a potential increased risk of bleeding. The primary outcome was all-cause inpatient mortality.
Circulation, Volume 150, Issue Suppl_1 , Page A4144999-A4144999, November 12, 2024. Current recommendations for pulmonary valve replacement (PVR) in TOF patients use indexed RV endiastolic volume (RVEDVi) to determine timing of PVR. In the presence of obesity, RVEDVi may underestimate the severity of RV volume load.
Circulation, Volume 150, Issue Suppl_1 , Page A4145271-A4145271, November 12, 2024. Pulmonary valve involvement is rare in LSE, and development of new disease while on recommended medical therapy represents unusual disease progression. Acute stroke workup was negative, and syncope was attributed to possible brief seizure.
Circulation, Volume 150, Issue Suppl_1 , Page A4143092-A4143092, November 12, 2024. LVWS was calculated from pulmonary capillary wedge pressure (PCWP) and LV wall thickness and radius using Law of Laplace and expressed in Pascals (Pa).
Circulation, Volume 150, Issue Suppl_1 , Page A4119267-A4119267, November 12, 2024. Advanced cardiac imaging especially in atypical presentations, can aid in early diagnosis.Case:A 59 year-old man with history of biopsy-proven pulmonary sarcoidosis presented with non exertional chest pain for 2 months.
That said — most patients eventually do become symptomatic ( Webb and Gatzoulis: Circulation 114: 1645-1653, 2006 ). NOTE: For more on ECG recognition of RVH and/or pulmonary hypertension ( re the qR pattern in lead V1 ) — See ECG Blog #234 and Blog #248. For more on ASD in Adults — Webb and Gatzoulis: Circulation 114: 1645-1653, 2006.
Circulation, Volume 150, Issue Suppl_1 , Page A4142158-A4142158, November 12, 2024. The RFCs were much more successful at classifying murmurs from the pulmonary and tricuspid valves (AUROC = 0.83 All RFC models were evaluated using the area under their receiver operating characteristic curves (AUROCs). and 0.65, respectively).
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