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Cholesterol crystals in the pathogenesis of atherosclerosis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 18 November 2024; doi:10.1038/s41569-024-01100-3 Cholesterol crystals (CCs) have a pathogenic role in various cardiovascular diseases, particularly atherosclerosis.

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Novel PCSK9 Inhibitor Cut LDL Cholesterol Levels by More Than Half

DAIC

milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.

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New Study Reveals 65 and Older Population Lowered Blood Pressure, Cholesterol, and Weight Using Mobile Technology

DAIC

milla1cf Wed, 04/24/2024 - 19:01 April 24, 2024 — Hello Heart , a digital leader in preventive heart health, today announced results from its latest study observing the benefits of scalable, accessible digital health tools for a growing senior population. Eighty percent of heart attacks and strokes are preventable.

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No Reduction in 90-Day Deaths, Heart Attacks With Human Apo/A1, A Building Block of HDL Cholesterol

DAIC

milla1cf Sat, 04/06/2024 - 18:32 April 6, 2024 — The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heart attack or stroke within three months of a prior heart attack, according to research presented at the American College of Cardiology ’s Annual Scientific Session.

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Lower your cholesterol early, and stick with it!

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 18 October 2024; doi:10.1038/s41569-024-01095-x Consumption of a high-fat diet leads to the progressive growth of atherosclerotic lesions.

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Ezetimibe Plus Statins Equals Better Outcomes

CardiacWire

However, not everyone with high cholesterol benefits from statins, leading many drug developers to focus on novel ways to lower LDL-C levels. Statins are one of the most prescribed drugs in the U.S., with over 25% of all adults 40 and up taking them. of patients with high LDL-C were on ezetimibe.

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Unexplained changes in cholesterol may help identify older adults at risk for dementia

Medical Xpress - Cardiology

When older adults have significant year-to-year fluctuations in their cholesterol levels without changes in medication, it could indicate an increased risk of developing dementia or cognitive decline, according to a preliminary study presented at the American Heart Association's Scientific Sessions 2024, held Nov.