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Nature Reviews Cardiology, Published online: 18 November 2024; doi:10.1038/s41569-024-01100-3 Cholesterol crystals (CCs) have a pathogenic role in various cardiovascular diseases, particularly atherosclerosis.
milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.
milla1cf Wed, 04/24/2024 - 19:01 April 24, 2024 — Hello Heart , a digital leader in preventive heart health, today announced results from its latest study observing the benefits of scalable, accessible digital health tools for a growing senior population. Eighty percent of heart attacks and strokes are preventable.
milla1cf Sat, 04/06/2024 - 18:32 April 6, 2024 — The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heart attack or stroke within three months of a prior heart attack, according to research presented at the American College of Cardiology ’s Annual Scientific Session.
Nature Reviews Cardiology, Published online: 18 October 2024; doi:10.1038/s41569-024-01095-x Consumption of a high-fat diet leads to the progressive growth of atherosclerotic lesions.
However, not everyone with high cholesterol benefits from statins, leading many drug developers to focus on novel ways to lower LDL-C levels. Statins are one of the most prescribed drugs in the U.S., with over 25% of all adults 40 and up taking them. of patients with high LDL-C were on ezetimibe.
When older adults have significant year-to-year fluctuations in their cholesterol levels without changes in medication, it could indicate an increased risk of developing dementia or cognitive decline, according to a preliminary study presented at the American Heart Association's Scientific Sessions 2024, held Nov.
Normal Cholesterol Levels. Just the same as you would expect with a blood pressure-lowering or cholesterol-lowering medication. 2024 Nov;30(11):1089-1096. npj Metab Health Dis 2 , 31 (2024). Not smoking. Adequate Sleep. Normal Blood Pressure. No Diabetes or Pre-Diabetes. For someone weighing 110 kg, that is a 27.5
This took place Thursday the 5 th of December 2024. In my opinion, or should I say ‘allegedly’ what actually happened here was that Barney Calman had heard from various cardiology experts that cholesterol and statin ‘deniers’ were causing people to stop taking their drugs. You may think it all finished months ago, not so.
This year, the cholesterol charity took on an international theme, looking at the global cardiovascular disease (CVD) prevention picture. HEART UK held its 37 th Annual Medical and Scientific Conference between 10 th –12 th July.
Nature Reviews Cardiology, Published online: 16 April 2024; doi:10.1038/s41569-024-01026-w A new study identifies a group of gut bacteria that can metabolize cholesterol and are associated with lower plasma cholesterol levels.
Nature Reviews Cardiology, Published online: 04 January 2024; doi:10.1038/s41569-023-00979-8 In this Review, Sarraju and Nissen summarize the clinical trial evidence for coronary atherosclerotic plaque stabilization and regression with plasma LDL-cholesterol-lowering therapy and other treatments.
The 2025 AHA Statistical Update is the product of a full years worth of effort in 2024 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members.
The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heart attack or stroke within three months of a prior heart attack, according to research presented at ACC.24, HDL cholesterol removes cholesterol from the arteries and carries it to the liver, which then excretes it.
tim.hodson Thu, 08/15/2024 - 10:32 Aug. 13, 2024 – The traditional lipid panel may not give the full picture of cholesterol-related heart disease risk for many Americans, according to a study led by UT Southwestern Medical Center researchers and published in JAMA Cardiology. Ann Marie Navar, M.D., population.
Methods We searched five databases until 12 March 2024 and used prediction study risk of bias assessment tool to assess bias. Laboratory predictors (eg, cholesterol and diabetes) had strong HRs, while body mass index in non-laboratory models showed limited effect. Design Systematic review. Protocol: PROSPERO (CRD42021291936).
The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Newly included risk factors— untreated vision loss and high LDL cholesterol —underscore the critical role of these elements in maintaining cognitive health.
A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight. statins). . - of their body weight.
The 2024 AHA Statistical Update is the product of a full year’s worth of effort in 2023 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members.
The 14 Factors Include: Hearing Loss High LDL cholesterol Less Education Traumatic Brain Injury Depression Social Isolation Hypertension Obesity Smoking Excess Alcohol Diabetes Physical Inactivity Air Pollution Visual Loss Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission When You Intervene Matters.
Circulation, Volume 150, Issue 9 , Page 724-735, August 27, 2024. Familial hypercholesterolemia (FH) is a genetic disease that leads to elevated low-density lipoprotein cholesterol levels and risk of coronary heart disease.
Nature Reviews Cardiology, Published online: 28 March 2024; doi:10.1038/s41569-024-01021-1 A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholesterol synthesis in the liver, which prevents an increase in circulating cholesterol levels.
milla1cf Sun, 04/07/2024 - 18:20 April 7, 2024 — An estimated 1 in 5 U.S. It is well known that high levels of low-density lipoprotein (LDL) cholesterol, known as the “bad” cholesterol, heighten cardiovascular risk. However, few treatments are currently available for this patient population, until now.
Heart Rhtyhm recently published two large cohort studies, Chen et al, 2024, “Low remnant cholesterol and the subsequent risk of new-onset atrial fibrillation: A prospective cohort study” (1) and Ouyang, et al 2024, “Remnant Cholesterol and New-onset Atrial Fibrillation: The Atherosclerosis Risk in Communities Study” (2).
Labelling of cholesterol as Good and bad , are immature scientific conclusions. Remember , there is no intravascular war going on between good and bad cholesterol. As I am writing this on October 7th , 2024 Nobel prize is being given to Victor Ambros and Gary Ruvkun, the team from UK & USA discovery of micro RNA.Congratulations.
Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01082-2 A single combined measurement of high-sensitivity C-reactive protein, LDL-cholesterol and lipoprotein(a) levels in plasma predicts incident cardiovascular events among women over a 30-year follow-up period, according to a new study.
Circulation, Volume 150, Issue Suppl_1 , Page A4137928-A4137928, November 12, 2024. Background:Inflammation and cholesterol jointly contribute to cardiovascular disease and mortality. female, mean age 46.8 ± 19.7 years , and 1905 cardiovascular deaths were documented. Conclusion:After a follow up of median 26.3
Stroke, Volume 55, Issue Suppl_1 , Page A47-A47, February 1, 2024. Introduction:Serum remnant lipoprotein particle cholesterol (RLP-C), which includes very-low density lipoproteins (VLDL) and its lipolytic products, contributes to atherosclerotic plaque formation. were women, and 15.7% were Black.
It still means you need to focus on good nutrition to achieve an optimal weight, and if you have other issues, such as high LDL cholesterol or high blood pressure, those may also need attention. British Journal of Sports Medicine 2024; 58: 556-566. Exercise just happens to be one of the biggest factors. But the evidence is super clear.
Nature Reviews Cardiology, Published online: 03 May 2024; doi:10.1038/s41569-024-01031-z In the AEGIS-II trial, infusion of apolipoprotein A-I to increase cholesterol efflux capacity did not improve outcomes in patients with acute myocardial infarction.
Marea Therapeutics emerged this week , announcing $190M in Series A/B funding and a mission to develop “a new generation of medicines for cardiometabolic diseases” – starting with their drug candidate targeting remnant cholesterol. Marea got its start from a tweet by UCSF cardiologist Ethan J.
Image courtesy: Getty Images christine.book Sat, 04/06/2024 - 15:33 April 6, 2024 — The Minneapolis Heart Institute Foundation ( MHIF ) is presenting leading research focused on trends in ST-elevation myocardial infarction (STEMI), the most severe form of a heart attack, at the American College of Cardiology ACC Annual Scientific Session , ACC.24
These cases are particularly challenging because traditional prevention strategies, which target known risks like high LDL cholesterol, hypertension, diabetes, and smoking, may not apply.
Untreated risk factors have a larger impact on risk for death following a serious heart event among survivors of childhood cancer relative to the general population, and therefore we shouldn’t just assume that because someone is young they don’t need risk factors like high blood pressure or high cholesterol treated.” Wendy Bottinor, MD.
A major risk factor for cardiovascular disease is a high blood level of low-density lipoprotein cholesterol (LDL-C), or “bad cholesterol,” that can be treated with statins. The company highlighted the significance of the study, reinforcing that cardiovascular disease is the number one cause of death and disability worldwide.
25 June 2024 In the case against the Mail on Sunday (Associated Newspapers) and Barney Calman, Health Editor of the Mail on Sunday. In short, we were effectively accused of being liars, and ‘ purveyors of misinformation ’ about statins (drugs that lower LDL/cholesterol). Now we have a judgment, part one. Step backwards for a moment.
Plaques that build up in the heart’s arteries contain fats, cholesterol and other substances; most heart attacks and serious cardiac events occur when pieces of such plaques break off and travel through the blood vessel, causing a blockage. During PCI, an operator inserts a stent into a blocked artery through a catheter in the groin or arm.
In this audio interview, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research being presented at the 2024 European Society of Cardiology annual meeting.
Circulation, Volume 150, Issue Suppl_1 , Page A4125511-A4125511, November 12, 2024. Background:Serum lipids and ratios are known to be associated with cardiovascular disease (CVD). However, studies on NHHR and the association with arterial stiffness in the US population have not been reported.
Credit: American Association of Critical-Care Nurses milla1cf Thu, 01/04/2024 - 11:00 January 4, 2024 — The days of prolonged fasting prior to cardiac catheterization may be numbered, as the body of evidence grows to allow patients to eat before the procedure.
Coronary artery disease is caused by the retention of a cholesterol particle in the artery wall. But if a retained cholesterol particle is the spark. BMC Med 22 , 114 (2024). This is the spark that sets the fire. Insulin resistance is the gasoline poured on that spark. On the far end of that line is type two diabetes.
Publication date: Available online 30 September 2024 Source: The American Journal of Cardiology Author(s): Andrea Raffaele Munafò, Marco Ferlini, Ferdinando Varbella, Fabrizio Delnevo, Martina Solli, Daniela Trabattoni, Luca Raone, Antonio Cardile, Paolo Canova, Roberta Rossini, Dario Celentani, Ludovica Maltese, Vittorio Taglialatela, Simona Pierini, (..)
Publication date: Available online 23 January 2024 Source: The American Journal of Cardiology Author(s): Shichiro Abe, Setus Nishino, Tomoaki Kanaya, Masashi Sakuma, Shigeru Toyoda
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