2024, BMI and Circulation - Cardiovascular Update

How Apob & Visceral Fat Increase Your Risk Of Heart Disease.

Dr. Paddy Barrett

DECEMBER 13, 2024

When it comes to cardiovascular disease, two of the biggest risk factors we must consider are: ApoB concentration - A measure of the number of circulating lipid particles. Not all circulating ApoB particles will transition across the artery wall, but some will. Relationship of BMI and Risk Of Diabetes.

Heart Disease

Heart Disease BMI Diabetes Cardiovascular Disease

Abstract 4146967: The Effects of Physical Activity Levels on Body Composition, Exercise Performance, Single Ventricle Function and Self-Perceived Quality of Life in Children and Adolescents with a Fontan Circulation.

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146967-A4146967, November 12, 2024. Overall BMI was normal, however 17% (5 of 30) were overweight or obese (Table 1).The Objectives:Physically active lifestyles are important for patients with congenital heart disease, including Fontan. The less active Fontan had higher fat% (24.8±8.7

Quality of Life

Quality of Life Exercise Circulation Congenital Heart Disease

Abstract 4146692: Cardiovascular Health Declines During Young Adulthood – An Electronic Health Record Study of >75,000,000 Individuals

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146692-A4146692, November 12, 2024. million for BMI, SBP, and smoking, respectively. Overall, ideal CVH metrics were more common than poor (Table), except for BMI. CVH available data varied: 2, 3.5, million for non-HDL, PA, and A1c, respectively; 28.8,

BMI

BMI Blood Pressure Diet Circulation

Abstract 4125500: Obesity-Related Left Atrial Functional Change Becomes Apparent in Infancy

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4125500-A4125500, November 12, 2024. Subjects were divided into 3 groups according to body mass index (BMI): normal (n=53), <17 kg/m2; overweight (n=28), 17 to 19.9 kg/m2; obese (n=15), ≧20 kg/m2. There was no significant difference in booster LA strain among the 3 groups.

Obesity

Obesity BMI Blood Pressure Circulation

Abstract Su404: Time difference between pad placement in double versus single external defibrillation: a live patient simulation model

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page ASu404-ASu404, November 12, 2024. The procedure was performed on two patient categories, with BMI 20,9 (patient A) and BMI 32,8 (patient B). Background:Out-of-hospital cardiac arrest (OHCA) cause significant patient morbidity and mortality.

Defibrillator

Defibrillator BMI Cardiac Arrest Circulation

Abstract 4115222: Distinct Demographic, Cognitive, and Psychosocial Factors Associated with Different Types of Self-Care in Patients with Type 1 Diabetes and in Patients with Type 2 Diabetes

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4115222-A4115222, November 12, 2024. 003), lower body mass index (BMI) (p =.040), 302), while lower BMI (p =.045) Background:Poor self-care in patients with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) leads to increased diabetes complications and health costs.

Diabetes

Diabetes BMI Diet Exercise

Abstract 4146930: Reported Stress Level is Associated with Cardiovascular Health in Young Adults – An Electronic Health Record Study of Nearly 1.4 Million Individuals

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146930-A4146930, November 12, 2024. We assessed Cosmos data from May 2022 through April 2024 to identify all YAs with reported stress data (5-point scale from “not at all” to “very much”). It is hypothesized that this decline may be related to competing demands (e.g.,

BMI

BMI Circulation

Abstract 4145649: Proteomics Characteristics of Patients with Acute Coronary Syndrome

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145649-A4145649, November 12, 2024. Circulating proteins levels were measured with the Olink-Explore 3072 panel. Proteins such as SSCD4 were significantly associated with BMI and lipids, suggesting a potential role in regulating lipid homeostasis. for all).

BMI

BMI Biomarkers Circulation

Abstract 4144999: Cardiac Magnetic Resonance Imaging in Tetrology of Fallot Patients and Relationship to Obesity

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4144999-A4144999, November 12, 2024. Obesity is associated with increased cardiovascular risk and adverse cardiac changes such as left ventricular hypertrophy (LVH) and in TOF higher body mass index (BMI) contributed to increase risk.

Obesity

Obesity BMI Pulmonary Circulation

Abstract 4142589: GLP-1 receptor agonists slow the progression of subclinical cardiovascular risk as detected from 12-lead electrocardiograms

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142589-A4142589, November 12, 2024. Compared to the control group, the GLP1RA cohort had a higher baseline risk profile (BMI: 35.1 [SD However, it is unclear whether early subclinical therapeutic changes can be detected from routine 12-lead electrocardiograms (ECGs).Methods:We

Electrocardiogram

Electrocardiogram BMI Myocardial Infarction Obesity

Abstract 4146852: Impact of Left Ventricular Diastolic Function in Pulmonary Arterial Hypertension Outcomes

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146852-A4146852, November 12, 2024. Results:Overall, 140 participants were identified (age: 56±16 years; BMI: 30.04±8.04 1-1.1), p=0.02) did significantly associate with outcomes individually and in a multivariable assessment with adjusting for age and BMI (Fig 1B).Conclusions:The

Pulmonary

Pulmonary Hypertension Preserved Ejection Fraction Outcomes

Abstract 4145350: Association of Zip Code and Incidence of Driveline Infection in Patients with Left Ventricular Assist Devices (LVADs): Do social determinants of health impact outcomes in LVAD recipients?

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145350-A4145350, November 12, 2024. Hispanic ethnicity (17% v 7%, p=0.016) and higher pre-implant BMI (mean 27.5 Of note, BMI was not predictive (HR 0.983, 95% CI: 0.937-1.031, p=0.475).Conclusion:In p=0.017) were associated with DLI (Table 1).

BMI

BMI Outcomes Laboratory Heart Failure

Abstract 4141387: Clinical Study on The Blood Pressure Changes in Patients with VEGFR-TKI-induced Hypertension During Anti-tumor Treatment

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141387-A4141387, November 12, 2024. Multivariate linear regression analysis revealed that after adjusting for tumor type and BMI, the use of VEGFR-TKI remained independently associated with nighttime average diastolic blood pressure (B=5.921,P=0.021). 13.21) vs. (80.41±10.71)

Blood Pressure

Blood Pressure Hypertension BMI Risk Factors

Abstract 4148106: Hemophilia and Cardiovascular disease in the United States: Prevalence, Risk factors, and outcomes.

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4148106-A4148106, November 12, 2024. 17.4]) and was also more likely to have diabetes mellitus, hyperlipidemia, chronic lung disease, chronic kidney disease, chronic liver disease, BMI ≥ 25, anemia, metastatic cancer, and atrial fibrillation.

Risk Factors

Risk Factors Cardiovascular Disease Coronary Artery Bypass Graft Outcomes

Abstract 4146960: Social Determinants of Health Associated With Worse Hypertension Stage in Low-Middle Income Country

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146960-A4146960, November 12, 2024. Median BMI was 27.6 Background:Hypertension (HTN) is a major risk factor for cardiovascular disease (CVD) and is the leading cause of morbidity and mortality globally, with a rise in prevalence in low and middle-income countries (LMIC).

Hypertension

Hypertension Blood Pressure BMI Risk Factors

Abstract 4142376: Impact of Atrial Fibrillation on Outcomes in Patients with Esophageal Cancer Receiving Neoadjuvant Chemoradiation

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142376-A4142376, November 12, 2024. Patients who developed AF were compared with patients who did not using propensity score matching (PSM) based on age, race, BMI, and multiple comorbidities. Patients who received adjuvant nivolumab were analyzed separately.

Atrial Fibrillation

Atrial Fibrillation Cancer Outcomes BMI

Abstract 4139929: The mechanisms of Mid-ventricular obstruction in patients with hypertrophic cardiomyopathy: Insight from an echocardiographic study

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4139929-A4139929, November 12, 2024. Background:Mid-ventricular obstruction (MVO) is a rare subtype of hypertrophic cardiomyopathy (HCM) , but it is associated with severe symptoms and worse clinical outcomes. Whereas the mechanisms of MVO has not fully elucidated.

Cardiomyopathy

Cardiomyopathy BMI Risk Factors Circulation

Abstract 4147807: Peak Oxygen Uptake Changes as a Function of Lean Mass After Cardiac Rehabilitation

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4147807-A4147807, November 12, 2024. years, BMI of 30.3±5.7, Introduction:Peak oxygen uptake (VO2peak), standardized to total body mass (ml/kg/min) is a predictor of morbidity and mortality in cardiovascular disease patients. Improvement in VO2peak was defined as >% increase.

Cardiac Rehabilitation

Cardiac Rehabilitation Exercise BMI Cardiovascular Disease

Abstract 4123899: Stroke Risk in Patients with an Isolated Interventricular Membranous Septal Aneurysm

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4123899-A4123899, November 12, 2024. The mean BMI was 27.9 Four patients with significant structural heart disease were excluded, resulting in a final sample size of 14. Of these, 9 (64%) were female with a mean age of 59.6, and 5 (36%) were male with a mean age of 55.4.

Aneurysm

Aneurysm Stroke Strokes Atrial Fibrillation

Abstract 4142557: Relationship between levels of nitric oxide (NO) concentration and flow-mediated vasodilatation test (FMD) in endothelial dysfunction development in overweight pregnant women with chronic hypertension.

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142557-A4142557, November 12, 2024. A physical examination was performed, heart rate was assessed, blood pressure was measured according to Korotkov method, body mass index (BMI) was calculated. Background:In Central Asia, hypertension accounts for 14.5%

Hypertension

Hypertension Blood Pressure Ultrasound Obesity

FDA Approves Wegovy for Cardiovascular Risk Reduction in Adults with Known Heart Disease and Overweight or Obesity

DAIC

MARCH 8, 2024

Getty Images milla1cf Fri, 03/08/2024 - 14:35 March 8, 2024 — Novo Nordisk today announced that the U.S. Last accessed February 2024. Last Accessed: February 2024. Last accessed: February 2024. Last accessed: February 2024.Available Last accessed: February 2024. Last accessed: February 2024.

Obesity

Obesity Heart Disease Heart attacks Heart Attack

Abstract WMP108: Association of Circulating Markers of Inflammation to Baseline and Progression of Carotid Artery Intima-Media Thickness

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP108-AWMP108, February 1, 2024. Multivariable linear regression was used to assess the association between circulating markers of inflammation with internal carotid artery (ICA) CIMT. Introduction:There is strong evidence of an association between systemic inflammation and ischemic stroke.

Circulation

Circulation BMI Atherosclerosis Cerebrovascular Disease

Abstract 4118122: Effect of Beta Blockers on Exercise Capacity, Diastolic Function, and Quality of Life in Patients with Heart Failure with Preserved Ejection Fraction

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4118122-A4118122, November 12, 2024. Patients studied were older (68 years old), white (90%), obese (average BMI 34 kg/m2) individuals with an average LVEF of 61%. Baseline demographics are shown in Table 1.

Quality of Life

Quality of Life Preserved Ejection Fraction Exercise Heart Failure

Abstract 4141061: Predicting Mortality Risk In patients With Heart Failure Using Respiratory Polygraphy And Esophageal Pressure During Sleep

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141061-A4141061, November 12, 2024. Observation time 2003-2024.AHI, Results were adjusted to age, sex, body mass index (BMI), and comorbidities.Results:Mean age 66 years (SD 12.019). Upper airway collapse during sleep increases respiratory effort.

Heart Failure

Heart Failure BMI Circulation Hospital

Abstract 4142963: Effects of high-intensity inspiratory muscle training as a pre-cardiac rehabilitation intervention on cardiovascular function in patients with heart disease: A pilot study

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142963-A4142963, November 12, 2024. Effect sizes presented based on between groups ANOVA.Results:There were no differences between groups for baseline age, BMI, sex, FMD%, PWV, mMRC, 6MWD and inspiratory muscle strength. An ANOVA was applied using the intention-to-treat analysis.

Cardiac Rehabilitation

Cardiac Rehabilitation Heart Disease BMI Outpatient

Abstract 4141539: Impact of Left Ventricular End-Diastolic Diameter on the Prognosis in Patients with Atrial Fibrillation and Acute Coronary Syndrome or Undergoing PCI

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141539-A4141539, November 12, 2024. Introduction:Atrial fibrillation (AF) is a common cardiac arrhythmia, the risk of cardiovascular adverse outcome rises when it coexists with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI).

Atrial Fibrillation

Atrial Fibrillation Coronary Artery Bypass Graft Coronary Artery Disease Myocardial Infarction

Abstract 4147830: Association Between Subcutaneous versus Visceral Adiposity and Type 2 Diabetes in United States Adults

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4147830-A4147830, November 12, 2024. Introduction:Visceral abdominal (VA) fat is an established risk factor for type 2 diabetes. adults 20-59 years from the 2011-2018 National Health and Nutrition Examination Survey (NHANES) with whole body DEXA scans. Females had a median 0.9 lbs (IQR, 0.5-1.3)

Diabetes

Diabetes BMI Risk Factors Circulation

Abstract 4138397: Gender Difference in Prevalence and Survival of Pulmonary Hypertension: A Prospective Cohort Study of 502,173 UK Biobank Participants

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4138397-A4138397, November 12, 2024. Background:Research into pulmonary hypertension (PH) reveals significant sex-based disparities in long-term survival rates.

Pulmonary

Pulmonary Hypertension BMI Outcomes

How Apob & Visceral Fat Increase Your Risk Of Heart Disease.

Abstract 4146967: The Effects of Physical Activity Levels on Body Composition, Exercise Performance, Single Ventricle Function and Self-Perceived Quality of Life in Children and Adolescents with a Fontan Circulation.

Abstract 4146692: Cardiovascular Health Declines During Young Adulthood – An Electronic Health Record Study of >75,000,000 Individuals

Abstract 4125500: Obesity-Related Left Atrial Functional Change Becomes Apparent in Infancy

Abstract Su404: Time difference between pad placement in double versus single external defibrillation: a live patient simulation model

Abstract 4115222: Distinct Demographic, Cognitive, and Psychosocial Factors Associated with Different Types of Self-Care in Patients with Type 1 Diabetes and in Patients with Type 2 Diabetes

Abstract 4146930: Reported Stress Level is Associated with Cardiovascular Health in Young Adults – An Electronic Health Record Study of Nearly 1.4 Million Individuals

Abstract 4145649: Proteomics Characteristics of Patients with Acute Coronary Syndrome

Abstract 4144999: Cardiac Magnetic Resonance Imaging in Tetrology of Fallot Patients and Relationship to Obesity

Abstract 4142589: GLP-1 receptor agonists slow the progression of subclinical cardiovascular risk as detected from 12-lead electrocardiograms

Abstract 4146852: Impact of Left Ventricular Diastolic Function in Pulmonary Arterial Hypertension Outcomes

Abstract 4145350: Association of Zip Code and Incidence of Driveline Infection in Patients with Left Ventricular Assist Devices (LVADs): Do social determinants of health impact outcomes in LVAD recipients?

Abstract 4141387: Clinical Study on The Blood Pressure Changes in Patients with VEGFR-TKI-induced Hypertension During Anti-tumor Treatment

Abstract 4148106: Hemophilia and Cardiovascular disease in the United States: Prevalence, Risk factors, and outcomes.

Abstract 4146960: Social Determinants of Health Associated With Worse Hypertension Stage in Low-Middle Income Country

Abstract 4142376: Impact of Atrial Fibrillation on Outcomes in Patients with Esophageal Cancer Receiving Neoadjuvant Chemoradiation

Abstract 4139929: The mechanisms of Mid-ventricular obstruction in patients with hypertrophic cardiomyopathy: Insight from an echocardiographic study

Abstract 4147807: Peak Oxygen Uptake Changes as a Function of Lean Mass After Cardiac Rehabilitation

Abstract 4123899: Stroke Risk in Patients with an Isolated Interventricular Membranous Septal Aneurysm

Abstract 4142557: Relationship between levels of nitric oxide (NO) concentration and flow-mediated vasodilatation test (FMD) in endothelial dysfunction development in overweight pregnant women with chronic hypertension.

FDA Approves Wegovy for Cardiovascular Risk Reduction in Adults with Known Heart Disease and Overweight or Obesity

Abstract WMP108: Association of Circulating Markers of Inflammation to Baseline and Progression of Carotid Artery Intima-Media Thickness

Abstract 4118122: Effect of Beta Blockers on Exercise Capacity, Diastolic Function, and Quality of Life in Patients with Heart Failure with Preserved Ejection Fraction

Abstract 4141061: Predicting Mortality Risk In patients With Heart Failure Using Respiratory Polygraphy And Esophageal Pressure During Sleep

Abstract 4142963: Effects of high-intensity inspiratory muscle training as a pre-cardiac rehabilitation intervention on cardiovascular function in patients with heart disease: A pilot study

Abstract 4141539: Impact of Left Ventricular End-Diastolic Diameter on the Prognosis in Patients with Atrial Fibrillation and Acute Coronary Syndrome or Undergoing PCI

Abstract 4147830: Association Between Subcutaneous versus Visceral Adiposity and Type 2 Diabetes in United States Adults

Abstract 4138397: Gender Difference in Prevalence and Survival of Pulmonary Hypertension: A Prospective Cohort Study of 502,173 UK Biobank Participants

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