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Therefore, the current systematic review investigated the clinical significance of NT-proBNP as a predictive biomarker in cardiac patients with depressive symptoms.MethodsTwo researchers independently performed an extensive search of published literature from inception until April 2024 on PubMed, Web of Science, and Cochrane Library in accordance with (..)
Nature Reviews Cardiology, Published online: 22 July 2024; doi:10.1038/s41569-024-01060-8 In this Roadmap arising from an NHLBI workshop, Chew and colleagues explore the use of retinal imaging biomarkers for the prediction, diagnosis and monitoring of systemic cardiovascular diseases.
milla1cf Mon, 04/22/2024 - 15:05 April 22, 2024 — At the annual American College of Cardiology conference ( ACC.24 milla1cf Mon, 04/22/2024 - 15:05 April 22, 2024 — At the annual American College of Cardiology conference ( ACC.24 This is an innovative platform for measuring biomarkers,” stated Dr. Karlsberg.
Nature Reviews Cardiology, Published online: 18 March 2024; doi:10.1038/s41569-024-01001-5 Non-coding RNAs are implicated in the pathophysiology of ischaemic heart disease and heart failure.
a biomarker-guided predictive care company, has presented data showing its FDA-cleared, non-invasive, biomarker-based technology for remote heart failure monitoring detected twice as many heart failure events as compared to the weight-based standard of care. christine.book Wed, 03/06/2024 - 14:51 March 6, 2024 — Bodyport Inc. ,
Video 8 in 8: Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC kchalko Thu, 05/23/2024 - 09:56 In this video in the 8 in 8 Series, Dr. Dwight Owen (Ohio State University) discussed advances in biomarker testing and neoadjuvant immunotherapy for resectable non-small cell lung cancer.
at the Society for Cardiovascular Angiography and Interventions' Scientific Sessions 2024. Using artificial intelligence in angiogram analysis can broaden diagnostic abilities and improve clinical decision-making, according to new research presented May 2 in Long Beach, Calif.,
The European Society of Cardiology (ESC) Congress 2024 (August 30 – September 2, 2024) has wrapped up, delivering groundbreaking insights into cardiovascular diseases and related conditions. Suggest using MRAs before beta-blockers in cases of resistant hypertension. Explore 2024 ESC Updated Guidelines here.
Stroke, Volume 55, Issue 4 , Page 801-811, April 1, 2024. This review highlights pathways that are aiding the search for sensitive and specific blood-based cerebrovascular dysfunction markers, describes promising candidates, and explains ongoing initiatives to discover blood-based VCID biomarkers.
The data was presented today by Amish Raval , MD, Director of Clinical Cardiovascular Research and Professor of Medicine at the University of Wisconsin-Madison at the Technology and Heart Failure Therapeutics (THT) 2024 annual meeting.
The PROACT study reported no impact on cardiotoxicity biomarkers or secondary endpoints related to heart function among patients who took high doses of enalapril, an ACE inhibitor, along with high doses of anthracyclines.
Circulation, Volume 150, Issue Suppl_1 , Page A4113047-A4113047, November 12, 2024. The top ten percent of commonly observed significant biomarkers were evaluated using four unique ML classifiers. The identified biomarkers served as potential indicators for early detection of CVDs.
Understanding the pathogenesis of SIMD is crucial for improving treatment, and microRNAs (miRNAs) have emerged as important regulators in this process.MethodsA comprehensive literature search was conducted in PubMed, Science Direct, and Embase databases up to September 2024.
Recent research suggested that the weight loss market was estimated to be worth $224 billion annually in 2021 and is estimated to exceed $400 billion by 2024 1. npj Metab Health Dis 2 , 31 (2024). 2024 Oct 31;391(17):1573-1583. 2024 Jun 21. 2024 Jun 8. Nat Med (2024). NEJM Nov 13 2024 N Engl J Med.
Circulation, Volume 150, Issue Suppl_1 , Page A4144785-A4144785, November 12, 2024. Exploring potential biomarkers from mitochondrial perspective may be effective in the diagnosis and treatment of PAH. Background:Acquired mitochondrial dysfunction is one of the characteristics of pulmonary arterial hypertension (PAH).
Innovative algorithms analyze gene biomarkers to provide predictive insights and personalized patient therapy. Point of Care Tests Point-of-care testing (POCT) quickly assesses cardiac biomarkers and other heart health indicators, aiding in prompt diagnosis and treatment decisions.
This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. 2024 May-Jun;18(3):e308-e319. The development of the Tina-quant Lipoprotein (a) Gen.2
mtaschetta-millane Wed, 07/10/2024 - 09:02 July 10, 2024 — CellProthera , a private company specializing in cell-based therapies for repairing ischemic tissues, and BioCardia, Inc. ,
Stroke, Volume 55, Issue Suppl_1 , Page A64-A64, February 1, 2024. Background:Atrial cardiopathy is associated with incident ischemic stroke in the absence of clinical atrial fibrillation in prospective cohorts.
Methods The online databases were searched from inception to July 2024, including the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, ClinicalTrials.gov. This meta-analysis sought to determine the efficacy of mavacamten and aficamten in hypertrophic cardiomyopathy. PROSPERO registration number CRD52024586161.
Stroke, Volume 55, Issue 1 , Page 31-39, January 1, 2024. Sensitivity and specificity of biomarker changes were analyzed in relation to predefined criteria for recurrent SH or asymptomatic change. Mean QSM and DCEQP of the SH lesion were acquired at baseline and at 1- and 2-year follow-ups.
Stroke, Volume 55, Issue Suppl_1 , Page ATP245-ATP245, February 1, 2024. It also identifies a novel biomarker for ischemic strokes from atherosclerosis. Background:Ischemic stroke can arise from various etiologies, such as cardioembolism, atherosclerosis, small vessel disease or cryptogenic.
Circulation, Volume 150, Issue Suppl_1 , Page A4146638-A4146638, November 12, 2024. Thus, levels above these thresholds for both apo B and hsCRP are associated with high ASCVD risk.Conclusion(s):The study demonstrates that apo B exhibits high discriminatory and diagnostic accuracy, making it a suitable ASCVD risk biomarker compared to hsCRP.
Image courtesy: IAS christine.book Tue, 07/23/2024 - 10:50 July 22, 2024 — The International Atherosclerosis Society ( IAS ) has released a clinical proceedings white paper outlining the role of inflammation in atherosclerosis and the importance of early intervention.
I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." Details of the study, included in a written statement issued by Caristo Diagnostics, follow. fold higher risk for cardiac mortality and 5.5-fold
Stroke, Volume 55, Issue Suppl_1 , Page AWP275-AWP275, February 1, 2024. Final unblinded results will provide a robust natural time course of specific biomarkers of neurodegeneration including GAP43. Forthcoming analyses evaluate broad panels of proteins, mRNA, and miRNA markers.
Getty Images mtaschetta-millane Wed, 07/10/2024 - 08:51 July 10, 2024 — Reviva Pharmaceuticals Holdings, Inc. , A significant reduction in key proinflammatory biomarkers following brilaroxazine treatment was recently shown in a large, global, pivotal Phase 3 study in patients with schizophrenia.
tim.hodson Wed, 12/18/2024 - 14:52 Dec. 11, 2024 Genetesis, Inc. The current version of the CardioFlux Score analyzes 14 unique biomarkers that quantify the heart muscle's electrical activity and then compares those results to a benchmark of healthy, symptom-free individuals. has launchedthe CardioFlux Membership program.
Stroke, Volume 55, Issue Suppl_1 , Page ATP12-ATP12, February 1, 2024. Results are a proof of concept that blood tests could replace more complex and costly imaging biomarkers in monitoring CA hemorrhage. Relative change in Phenylacetylglutamine and LPE.18.0+Piperine
milla1cf Tue, 06/11/2024 - 18:41 June 11, 2024 — A newly developed radiotracer can generate high quality and readily interpretable images of cardiac amyloidosis, a condition referred to as the “Alzheimer’s disease of the heart.” This research was presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.
Circulation, Volume 150, Issue Suppl_1 , Page A4136687-A4136687, November 12, 2024. These findings suggest that VTRNA2-1 promoter methylation status could serve as a valuable biomarker for predicting prognosis and guiding treatment strategies in PAD. 6.97, p=0.024), amputations (HR 2.58, 95% CI 1.02-6.57,
tim.hodson Thu, 09/19/2024 - 09:42 Sept. 18, 2024 – Astellas Pharma Inc. recently announced that Digitiva, a non-invasive digital health solution for heart failure management, has been listed with the U.S. Food and Drug Administration (FDA). a smartphone app designed for heart failure patients and built on the Welldoc, Inc.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP119-ATMP119, February 1, 2024. Some of the biomarkers were unchanged (Table). Diabetes doubles the risk of VCID. The underlying reasons are not understood, and preventive therapeutic strategies are lacking.
mtaschetta-millane Wed, 03/27/2024 - 08:08 March 27 2024 — HeartFlow, Inc. , Observed outcomes and biomarkers are secondary endpoints. JSCAI 2024 Tzimas et al. The DECIDE Registry, which aims to include 10,000 patients from approximately 25 sites across the U.S., Rinehart et al.
Stroke, Volume 55, Issue Suppl_1 , Page AWP169-AWP169, February 1, 2024. TEG-R time may be a useful biomarker in DOAC reversal with PCC. Prothrombin complex concentrates (PCCs) are used to emergently reverse direct-acting oral anticoagulant (DOAC) activity. Measuring the degree of anticoagulation reversal in this population is limited.
Publication date: Available online 4 June 2024 Source: The American Journal of Cardiology Author(s): Carine E. Hamo, Richard Liu, Wenbo Wu, Rebecca Anthopolos, Sripal Bangalore, Claes Held, Ifitkhar Kullo, Kreton Mavromatis, Bruce McManus, L. Kristin Newby, Harmony R. Reynolds, Kelly V. Ruggles, Lars Wallentin, David J. Maron, Judith S.
Video The Surgeon’s Role in Managing Patients with Resectable NSCLC smccarthy Fri, 03/08/2024 - 14:51 In this video, Dr. Leah Backhus, thoracic surgeon and professor of cardiothoracic surgery at Stanford Medicine, discusses the surgeon’s role in managing patients with resectable non-small cell lung cancer.
BACKGROUND:Arterial stiffness, as measured by arterial pulse wave velocity (PWV), is an established biomarker for cardiovascular risk and target-organ damage in individuals with hypertension. Hypertension, Ahead of Print.
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