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Abstract TMP112: Von Willebrand Factor (VWF) Modulates Smooth Muscle Cell Proliferation During the Outward Remodeling of Leptomeningeal Collateral Arterioles Following Stroke

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page ATMP112-ATMP112, February 1, 2024. Our findings also provide evidence for VWF within the smooth muscle layer of pig and human brain arterioles, supporting the broader potential role of VWF as a molecular player in vascular remodeling.

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Lifelong dietary interventions linked to improved retinal health and reduced cardiovascular risk

Cardiology Update

Participants in the intervention group displayed less tortuous arterioles and venules and an increased arteriolar fractal dimension compared to the control group. Several lifelong cumulative cardiovascular risk factors, such as cumulative systolic blood pressure, were independently linked to narrower arterioles. European Heart Journal.

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Thrombin in Pregnancy and Preeclampsia: Expression, Localization and Vasoactivity in Brain and Microvessels from Rats

Journal of Cardiovascular Pharmacology

We characterized thrombin expression and vasoactivity in brain cerebral parenchymal arterioles (PAs) in rat models of pregnancy and PE. We characterized thrombin expression and vasoactivity in brain cerebral parenchymal arterioles (PAs) in rat models of pregnancy and PE. Copyright © 2024 Wolters Kluwer Health, Inc.

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Abstract 4141446: Sodium Glucose Co-transporter 2 (SGLT2) Inhibitors Promote Resiliency to High Pressure Stress in the Human Microvasculature

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4141446-A4141446, November 12, 2024. Emerging evidence suggests that vascular stress from cardiovascular-related co-morbidities promotes microvascular dysfunction, a key component in the development of heart failure with preserved ejection fraction.

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Abstract WP297: Time-Dependent Effects of Drag-Reducing Polymers Administration on Permanent Middle Cerebral Artery Occlusion Injury in Rats

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWP297-AWP297, February 1, 2024. 6 hrs) increased near-wall blood flow velocity and flow rate in arterioles, leading to an increase in the number of erythrocytes entering capillaries, capillary perfusion and oxygenation while protecting BBB compared to saline (p<0.05). from baseline).