Ablation of Cardiac Arrhythmias: Past, Present, and Future
Circulation
JUNE 30, 2024
Circulation, Volume 150, Issue 1 , Page 4-6, July 2, 2024.
2024 Arrhythmia Circulation 
Abstract 4138334: Identification and Immunological Characterization of Arrhythmia-Related Molecular Clusters in Ischemic Cardiomyopathy
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4138334-A4138334, November 12, 2024. Ischemic cardiomyopathy, a severe cardiac condition resulting from prolonged myocardial ischemia, is characterized by ventricular dilation, dysfunction, and an increased risk of life-threatening arrhythmias.
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Atrial Arrhythmias After PFO Device Closure: Common, Clinically Important, and Preventable?
Circulation
NOVEMBER 17, 2024
Circulation, Volume 150, Issue 21 , Page 1669-1670, November 19, 2024.
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Giants Hiding in Small Places: A Case of New Onset Heart Failure, Atrioventricular Block, and Ventricular Arrhythmias
Circulation
FEBRUARY 4, 2024
Circulation, Volume 149, Issue 6 , Page 475-480, February 6, 2024.
Abstract Su505: Impact of a Targeted Automated External Defibrillator (AED) Program on Survival After Ventricular Fibrillation Cardiac Arrest in the Sao Paulo Metropolitan Subway System: A Landmark Initiative in Latin America
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page ASu505-ASu505, November 12, 2024. The targeted Automated External Defibrillator (AED) program in the Sao Paulo Metro has yielded promising results in improving survival rates for individuals experiencing out-of-hospital cardiac arrest (OHCA) due to ventricular arrhythmias.
Boston Scientific Initiates AVANT GUARD Clinical Trial to Evaluate FARAPULSE Pulsed Field Ablation System as First-Line Treatment for Persistent Atrial Fibrillation
DAIC
DECEMBER 29, 2023
Unlike paroxysmal AF, which describes symptoms that last for seven days or fewer, persistent AF is a sustained arrhythmia that lasts for more than a week 1. Circulation. Early treatment of persistent AF can reduce the risk of blood clots, stroke, and heart failure, and may prevent the disease from becoming permanent.
Correction to: Pharmacological Management of Cardiac Arrhythmias in the Fetal and Neonatal Periods: A Scientific Statement From the American Heart Association
Circulation
MARCH 17, 2024
Circulation, Volume 149, Issue 12 , Page e996-e996, March 19, 2024.
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Antithrombotic Strategies When Using Epicardial Carbon Dioxide Insufflation During Percutaneous Epicardial Access
Circulation: Arrhythmia and Electrophysiology
NOVEMBER 27, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 12 , Page e013310, December 1, 2024.
His-Ventricular Interval and Incident Pacemaker Implant in Over 3000 Ambulatory Patients Undergoing Invasive Electrophysiologic Procedures
Circulation: Arrhythmia and Electrophysiology
NOVEMBER 27, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 12 , Page e013285, December 1, 2024.
Tumescent Local Anesthesia During Cardiac Implantable Electronic Device Implantation to Reduce Postoperative Pain
Circulation: Arrhythmia and Electrophysiology
NOVEMBER 27, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 12 , Page e013168, December 1, 2024.
Self-Administered Etripamil Nasal Spray Relieved Symptoms, Decreased Heart Rate, and Reduced Medical Interventions During Atrioventricular Nodal–Dependent Paroxysmal Supraventricular Tachycardia
Circulation: Arrhythmia and Electrophysiology
NOVEMBER 27, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 12 , Page e011681, December 1, 2024.
Abstract 4136459: Machine Learning in Time-to-Event Prediction of Ventricular Arrhythmias among Older Adults with Type 2 Diabetes and Coronary Artery Disease
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4136459-A4136459, November 12, 2024. Ventricular arrhythmias (VA), such as ventricular fibrillation and ventricular tachycardia, are the major causes of mortality among patients with CAD.
Editors and Editorial Board
Circulation: Arrhythmia and Electrophysiology
JANUARY 16, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 1 , Page e000091, January 1, 2024.
Retraction of: Systematic Treatment Approach to Ventricular Tachycardia in Cardiac Sarcoidosis
Circulation: Arrhythmia and Electrophysiology
JANUARY 15, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 1 , Page e000090, January 1, 2024.
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Heart Disease and Stroke Could Affect at Least 60% of Adults in U.S. by 2050, According to American Heart Association Advisories
DAIC
JUNE 18, 2024
trillion by 2050, according to two presidential advisories published in the AHA journal Circulation. christine.book Tue, 06/18/2024 - 11:22 June 18, 2024 — At least 6 in 10 adults in an older, more diverse U.S. The landscape of cardiovascular disease in the U.S.
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105 Abstract 4137488: Mild elevation of [K+]0 reduces atrial fibrillation burden and enhances the efficacy of flecainide to suppress the arrhythmia: an experimental study.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4137488-A4137488, November 12, 2024. Background:It is desirable to improve rhythm control management of atrial fibrillation (AF). Extracellular potassium ([K+]0) may affect AF generation and anti-AF efficacy of the sodium channel blockers.Methods:AF burden (i.e.,
Biosense Webster Study Supports Low and Zero Fluoroscopy Workflow as Safe, Effective Alternative to Conventional Catheter Ablation
DAIC
FEBRUARY 2, 2024
milla1cf Fri, 02/02/2024 - 17:02 February 2, 2024 — Biosense Webster, Inc. , a global leader in cardiac arrhythmia treatment and part of Johnson & Johnson MedTechi , revealed findings from a company-funded study of real-world data. Circulation Research. Int J Stroke. 2021 Feb;16(2):217-221. Benjamin EJ, Schnabel RB.
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Abstract 4143083: Cardiomyopathy in Pregnancy Complicated by Loeys-Dietz Syndrome
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4143083-A4143083, November 12, 2024. She underwent a cesarean section at 32 weeks given ongoing arrhythmia and heart failure symptoms. Her arrhythmia burden continued to lessen. Cardiomyopathy and arrhythmia have been described in a small number of cases.
Abstract 4146485: Clinical Validation of an AI-enabled ECG Holter Analysis Platform
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4146485-A4146485, November 12, 2024. The presence or absence of five predetermined cardiac arrhythmias were evaluated: atrial fibrillation/flutter (AFIB), ventricular bigeminy, ventricular trigeminy, ventricular tachycardia (VT), and high-grade atrioventricular block (AVB).Results:The
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A teenager involved in a motor vehicle collision with abnormal ECG
Dr. Smith's ECG Blog
FEBRUARY 6, 2024
Circulation: Cardiovascular Imaging. Other Arrhythmias ( PACs, PVCs, AFib, Bradycardia and AV conduction disorders — potentially lethal VT/VFib ). NOTE: Prediction of cardiac contusion "severity" on the basis of cardiac arrhythmias and ECG findings — is an imperfect science. Myocardial contusion in an 8-year-old boy. Cramer, M.
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ECG Blog #416 — Is the Rhythm and ECG related?
Ken Grauer, MD
FEBRUARY 9, 2024
Whatever the specific etiology of today's arrhythmia is, the “good news” is — that this rhythm will most probably improve with reperfusion of the "culprit" artery. That said — I found today's arrhythmia fascinating, and worthy of more in-depth analysis. Using calipers facilitates the process.
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Lesion Morphometry of the Pentaspline Pulsed Field Ablation Catheter: Understanding Catheter Pose, Rotation, and Dosing
Circulation: Arrhythmia and Electrophysiology
NOVEMBER 29, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 12 , Page e013208, December 1, 2024. BACKGROUND:The pentaspline pulsed field ablation catheter achieves pulmonary vein isolation using 8 stacked, pose-specific applications with rotation.
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40 Abstract 4140767: MRI-Measured Myocardial Strain as a Predictor of Clinical Outcomes in Systemic RV.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4140767-A4140767, November 12, 2024. Background:Systemic RV dysfunction is a common concern in patients with d-Transposition of the great arteries (d-TGA) after atrial switch and congenitally corrected TGA (ccTGA). Clinical events (e.g., for each) except 3D global radial strain.
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40 Comparison of Procedural Outcomes of Lumenless Fixed-Helix Versus Stylet-Driven Extendable-Helix Lead Systems in Left Bundle Branch Pacing: COMPARE LBBP
Circulation: Arrhythmia and Electrophysiology
NOVEMBER 29, 2024
Circulation: Arrhythmia and Electrophysiology, Volume 17, Issue 12 , Page e013385, December 1, 2024. BACKGROUND:Left bundle branch pacing (LBBP) has emerged as a safe and effective alternative to right ventricular pacing.
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Abstract 4143624: The QTc Dilemma in Pediatric DKA: Which correction formula to use?
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4143624-A4143624, November 12, 2024. Current pediatric DKA management guidelines should include routine 12-lead ECGs and venous blood gas analyses with electrolytes to monitor QTc changes and mitigate arrhythmia risks. An increase in ionized calcium is also noted in DKA.
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Abstract 4135265: When the Beat Drops: A Pilot Project for a Case-Based Resident’s Guide to Cardiovascular Care
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4135265-A4135265, November 12, 2024. Topics included management of arrhythmias, structural heart disease, ischemia, cardiogenic shock, and post-procedure complications. Topics with high traffic included chapters regarding arrhythmias and post-procedural complications.
Abstract 4140882: Peak Stroke Incidence Following Left Atrial Appendage Closure
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4140882-A4140882, November 12, 2024. Introduction:Atrial fibrillation (A fib) is the most common arrhythmia affecting 1-2% of the general population. A fib is a well-established risk factor for ischemic strokes.
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40 Abstract 4147424: In hospital Outcomes of Acute Myocarditis in Adults with Systemic Inflammatory Disease: A Population-based Analysis in The United States
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4147424-A4147424, November 12, 2024. Systemic inflammatory diseases (SID) are associated with adverse cardiovascular (CV) events, due to derangement in innate immunity. Six SID were selected based on HLA antigen distribution.
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Abstract 4140419: Targeting Cardiac Fibrosis with Chimeric Antigen Receptor Neutrophils from Human Pluripotent Stem Cells
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4140419-A4140419, November 12, 2024. Current treatments, predominantly pharmacological, target signaling pathways involved in fibroblast activation but often come with side effects such as cardiac toxicities.
How terrible can it be to fail to recognize OMI? To whom is OMI Obvious or Not Obvious?
Dr. Smith's ECG Blog
OCTOBER 8, 2024
Click here to sign up for Queen of Hearts Access Here is the cardiologist's formal interpretation : "sinus rhythm with marked sinus arrhythmia, left ventricular hypertrophy with repolarization abnormality, and anteroseptal infarct, age undetermined." There is intense blue where the hyperacute T-waves are on this explainability map.
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Abstract 4146863: Efficacy of Hydralazine-Isosorbide-Dinitrate and Sodium-glucose Cotransporter-2 Inhibitors in Reducing Short-Term Readmission in African Americans with Advanced Heart Failure
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4146863-A4146863, November 12, 2024. Introduction:The treatment of heart failure (HF) with hydralazine-isosorbide dinitrate (H-ISDN) in African Americans (AA) with New York Heart Association (NYHA) III-IV who remain symptomatic despite optimal medical therapy is a class Ia indication.
Abstract 4142012: Ectasias of Multiple Coronary Arteries and a Coronary Cameral Fistula Between Right Coronary Artery and Coronary Sinus
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4142012-A4142012, November 12, 2024. However some patients can develop heart failure, angina, and arrhythmia due to significant intracardiac shunt or coronary steal phenomenon. No murmur or extra heart sound were heard, and the lung sounds were normal. It is often clinically silent.
Left Atrial Strain to Predict Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting
Circulation: Cardiovascular Imaging
JANUARY 15, 2024
Circulation: Cardiovascular Imaging, Volume 17, Issue 1 , Page e015969, January 1, 2024. The optimal cutoff value for the arrhythmia prediction was a global PALS value <28%, with a specificity of 86% and a sensitivity of 36%. P<0.001). and 85.7%, respectively (P<0.001).
Abstract 4143264: A Case of Spike-on-T Phenomenon and Polymorphic Ventricular Tachycardia
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4143264-A4143264, November 12, 2024. This can initiate ventricular arrhythmias like polymorphic ventricular tachycardia (PMVT). Background:R-on-T phenomenon occurs when an electrical stimulus is delivered at a critical point during ventricular repolarization.
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Abstract 4142494: Prediction Of Atrial Fibrillation From Beat-To-Beat Correlations During Normal Rhythm
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4142494-A4142494, November 12, 2024. Background:Atrial fibrillation (AF) is the most common type of cardiac arrhythmia, affecting over 59 million individuals worldwide.
Abstract 4141007: Incidence of positive cardiac positron emission tomography in genotype-positive patients: A Cardiovascular Genetics Clinic lens
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4141007-A4141007, November 12, 2024. Background:Positron emission tomography-computed tomography (PET-CT) is widely used to diagnose cardiac sarcoidosis (CS) for treatment.
Abstract 4134590: Procedural Related Major Adverse Events of Cardiac Catheterization in Pediatric Patients with Cardiomyopathy: Insights from IMPACT Registry
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4134590-A4134590, November 12, 2024. The most common MAE was arrhythmia, representing 46% of MAE, followed by cardiac arrest and bleeding each 20%. We aim to describe the rate of MAE in children with cardiomyopathy undergoing cardiac catheterization. MAE was present in 1.6%.
Abstract 4140212: Cardiac Electrophysiologic Response to Single-dose AUX-001, a Once-Daily Extended-Release Nicorandil in Development for Chronic-stable Angina in Adult Healthy Volunteers under Fasting and Fed Conditions
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4140212-A4140212, November 12, 2024. Findings also confirm previous healthy volunteer trials with IR NIC highlighting no tendency promoting arrhythmia in normal, non-ischemic myocardium.
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ECG Blog #425 — Are there P Waves?
Ken Grauer, MD
APRIL 13, 2024
That said — most patients eventually do become symptomatic ( Webb and Gatzoulis: Circulation 114: 1645-1653, 2006 ). P utting I t A ll T ogether: At this point in my assessment of today's rhythm — I fully acknowledge that I did not know for certain the etiology of this arrhythmia. Many patients go years without significant symptoms.
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A 90-something with acute stroke. She has no chest symptoms. What is the diagnosis?
Dr. Smith's ECG Blog
NOVEMBER 11, 2023
The Queen of Hearts AI app will hopefully be FDA approved in Q1 of 2024. Dr. Smith circulated the initial ECG in today's case ( that I reproduce in Figure-1 ) to our group — initially without him yet knowing anything about this patient. It is already approved in Europe. Figure-1: The initial ECG in today's case.
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ECG Blog #417 — AFib with Aberrancy?
Ken Grauer, MD
FEBRUARY 15, 2024
The above said — On occasion, there may be focal triggered activity that results in the marked irregularity of the monomorphic VT seen in ECG #1 ( Zhang et al — Circulation 139:1750-1752, 2019 ). A DDENDUM ( 2/17/2024 ) : — — E CG M edia P EARL # 15 ( 5 minutes Audio ) — Is Monomorphic VT a regular rhythm?
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ECG #413 — A Pre-Op ECG in an ASx Patient
Ken Grauer, MD
JANUARY 20, 2024
PEARL # 7: As is evident for many of the examples of AV block that have appeared in this ECG Blog — it is common to see a " ventriculophasic " sinus arrhythmia in association with 2nd or 3rd degree AV block. A DDENDUM ( 1/20/2024 ) : Included below is a series of additional material relevant to today's case.
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Syncope while on a treadmill
Dr. Smith's ECG Blog
SEPTEMBER 18, 2024
Continue Eliquis 5mg BID, should be continued for 3 months == MY Comment , by K EN G RAUER, MD ( 9/18 /2024 ): == I found the following aspects of today's case of special interest. At discharge Continue amiodarone 400 mg PO BID x2 weeks then 200 mg daily until follow-up Continue Toprol XL 25 mg daily. Sinus tachycardia does not go this fast.
iRhythm Unveils New Data Demonstrating Benefits of Long-Term Continuous Monitoring for Arrhythmia Detection
DAIC
MARCH 31, 2025
arrhythmia yield versus 69.1% in daily-symptom patients, demonstrating that greater symptom frequenc y does not necessarily reflect increased arrhythmia burden. arrhythmia yield versus 69.1% in daily-symptom patients, demonstrating that greater symptom frequenc y does not necessarily reflect increased arrhythmia burden.
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