Remove 2023 Remove Myocardial Infarction Remove Plaque
article thumbnail

Dynamic OMI ECG. Negative trops and negative angiogram does not rule out coronary ischemia or ACS.

Dr. Smith's ECG Blog

Thus, it has recently become generally accepted that most plaque ruptures resulting in myocardial infarction occur in plaques that narrow the lumen diameter by 40% of the arterial cross section may be involved by plaque. Fig 1 shows typical examples of two such plaques.

Ischemia 122
article thumbnail

What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

Dr. Smith's ECG Blog

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. MINOCA I do not have the bandwidth here to write a review of MINOCA.

article thumbnail

American College of Cardiology ACC.24 Late-breaking Science and Guidelines Session Summary

DAIC

24 will focus on the following three current guideline updates: American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines 2023 Atrial Fibrillation Guideline - Pharmacology II: Strokes vs. Bleeds, What Do the Guidelines Tell Us About Practical Management in A-fib? The Guidelines Sessions at ACC.24

article thumbnail

Three normal high sensitivity troponins over 4 hours with a "normal ECG"

Dr. Smith's ECG Blog

So there is probability of myocardial injury here (and because it is in the correct clinical setting, then myocardial infarction.) Although it is statistically unlikely, multiple plaque ruptures are possible. The PDA plaque was also bulky, but was not described as inflamed or ulcerated. Heitner et al.

Angina 121
article thumbnail

HDAC9 Inhibition as a Novel Treatment for Stroke

Stroke Journal

Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023. The antiseizure drug sodium valproate, which has nonspecific HDAC inhibitory properties, both inhibits atherosclerosis in animal models and is epidemiologically associated with reduced stroke and myocardial infarction risk in man.

Stroke 40
article thumbnail

Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury

Circulation

Circulation, Volume 148, Issue 24 , Page 1958-1973, December 12, 2023. Permanent coronary ligation was performed to establish myocardial infarction (MI). Compared with animals without PCOS, PCOS animals showed significantly exacerbated atherosclerotic plaque development and post-MI cardiac remodeling.

article thumbnail

See this "NSTEMI" go unrecognized for what it really is, how it progresses, and what happens

Dr. Smith's ECG Blog

Therefore it means acute type 1 ACS plaque rupture with impeded flow and impending full occlusion until proven otherwise. A New ST-segment elevation myocardial infarction equivalent pattern? Association between opioid analgesia and delays to cardiac catheterization of patients with occlusion Myocardial Infarctions.