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Simultaneous pancreas-kidney (SPK) transplants are known to improve the quality of life and long-term survival of patients with insulin dependent diabetes and advanced renal disease. I have witnessed firsthand the significant benefits for patients with diabetes and kidney failure of receiving a pancreas and kidney transplant.
To tackle this problem, researchers compared Veterans Affairs data on 2 million T2D patients (2017-2023) taking either GLP-1s , DPP4is, SGLT2is, or usual care antihyperglycemics over a 3.68 Starting with the good news, GLP-1s lowered risks for 42 health outcomes while increasing risks for 19 outcomes. year follow-up.
Late-breaking second year results from the PROMISE II trial showed that the LimFlow system achieved strong outcomes for avoiding amputations and promoting limb salvage among “no-option” patients with chronic limb-threatening ischemia (CLTI). LimFlow gained FDA approval in September 2023, and was soon acquired by Inari Medical for up to $415M.
2-5, 2023, to gain perspective on the latest advances in the management of glomerular disease. Kidney Week 2023 not only served as a platform for the latest news and updates in the field but also marked the final meeting of the year for practitioners in the specialty of nephrology.
Cardiometabolic conditions – specifically obesity, diabetes and heart disease – disproportionately affect the 60 million people in the U.S. Rodriguez presents to hundreds of practitioners of women's health on using digital tools and community intervention to improve outcomes in underserved ethnic populations. with Hispanic heritage.
Introduction:Many national initiatives have focused on increasing public awareness of acute ischemic stroke (AIS) symptoms because earlier treatment is associated with improved outcomes. From 2014-2023, there was a downward trend in the early LKWA0-4.5 1.66]), and comorbidities of diabetes (1.29 [1.18-1.41]), The LKWA>4.5
Neha Agarwal, PhD, Clinical Director at Cardiometabolic Health Congress , Informa Connect, recently presented significant findings at the 84th American Diabetes Association (ADA) Scientific Sessions. The Diabetes Track will feature: “Precision Medicine in Diabetes” by Jose C.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. vs 72, p<0.001) compared to patients who did not have poorly controlled diabetes. or greater.
This year’s theme, “Advancing Cardiovascular Care for All” brings the latest practice-changing breakthroughs, along with top experts debating and discussing outcomes of highly-anticipated clinical trials. 24 from April 6 - 8, 2024 in Atlanta, GA at the Georgia World Congress Center. The Guidelines Sessions at ACC.24
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. However, there is ongoing debate whether intensive BP lowering may paradoxically increase the risk of cardiovascular disease (CVD), especially in patients with type 2 diabetes (T2D). per 1000 person‐years experienced the primary outcome.
Propensity score-matched analysis (PSM) (1:1) was performed on age, gender, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, LDL level, left ventricular ejection fraction and various drugs including beta blockers, ACEi and ARBi.
This study aims to investigate the relationship between sdLDLC level and PP in patients with stable coronary artery disease.MethodsWe conducted a retrospective analysis of 146 lesions in 86 patients by repeat intravascular ultrasound examinations from January 2020 to May 2023. P=0.006), especially in diabetic patients (Pearsonr=0.58,P<0.001).
Propensity score-matched analysis (PSM) (1:1) was performed with matching for age, gender, race, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, low-density lipid (LDL) level, left ventricular ejection fraction, and various drugs including ACEi, ARBi, ARNI, beta-blockers, and diuretics.
Background:Clinical trials have demonstrated that sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1RA) reduce cardiovascular (CV) risk in patients (pts) with type 2 diabetes (T2D) with or at high risk for CV disease. 1.04, P=0.3). 0.98, P=0.025).Conclusions:Among
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. 1) Nevertheless, published research on endovascular treatment outcomes in this population is scarce. 001), diabetes (29.8% 001), diabetes (29.8% Patients were matched by baseline characteristics. vs. 27.1%, p=.001), vs. 15.3%, p=.019),
The International Journal of Cardiovascular Science (IJCS) is accepting articles for a special thematic issue focusing on cardiometabolic diseases, to be published in September 2023. The term cardiometabolic risk describes the chances that a person has of damaging the cardiovascular system when one or more risk factors appear together.
Background:The STRACK project aims to improve post-stroke patient management and the transition from acute to primary care thanks to improvements in patient pathways and monitoring cardiovascular risk factors: heart failure, diabetes, atrial fibrillation, dyslipidemia and hypertension.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe Appalachia region of North America is known to have significant health disparities, specifically, worse risk factors and outcomes for stroke.
Semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes, according to new research. In the trial, patients treated with semaglutide lost an average of 9.4%
Insulin resistance is a precursor condition to metabolic syndrome and type 2 diabetes, both major drivers of heart disease. 2023 Jul;4(7):e345-e353. 2023 May;31(5):1204-1215. 2023 May 23;100(21):e2191-e2203. 2023 Feb 6;69:101764. Poor Sleep Is A Major Risk Factor For Insulin Resistance. Lancet Healthy Longev.
This study examines prognostic factors in a multiethnic Latin American cohort with CCAD, aiming to identify key predictors of outcomes in this diverse population.Methods:We conducted a 6-month follow-up study, assessing clinical outcomes in patients diagnosed with CCAD. black, median age 45 (SD: 13.9). with mRS 0-2).
Methods:We retrospectively collected baseline demographic, clinical, and radiographic data on 27 patients who presented as a stroke alert within 24 hours of symptoms and had extensive (from bifurcation to distal ICA) occlusion by computerized tomography angiography from 2019-2023 at our institution.
The purpose of this systematic review is to evaluate, describe, and compare existing models and analyze the factors that can predict outcomes. Databases including Embase, PubMed, The Cochrane Library, Web of Science, CNKI, Wanfang Data, VIP, and SINOMED were comprehensively searched for identifying studies published from 1977 to 19 May 2023.
Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke risk factors like hypertension, diabetes, and atrial fibrillation. The first period, from July 2022 through June 2023, represents the timeframe before the opening of the transition-of-care clinic.
Evaluate the benefit in important cardiovascular outcomes and safety in elderly patients of a blood pressure control ≤ 130mmHg compared to standard of care.Methods:The research was performed in PubMed, EMBASE, Scielo, LILACS, and Cochrane Central Register of Controlled Trials (CENTRAL) from January 1st, 2013 to May 1st, 2023.
Introduction:In large vessel occlusion (LVO) ischemic stroke patients, better functional outcomes are associated with achieving modified thrombolysis in cerebral infarction (mTICI) score 2C/3 in comparison to 2B. Primary outcome measure was achieving mTICI 2C/3 (i.e., excellent) revascularization. were female.
A 56 year old male with a history of diabetes, dyslipidemia, hypertension, and coronary artery disease presented to the emergency department with sudden onset weakness, fatigue, lethargy, and confusion. For more on use of Opiates with acute ischemic CP — See the January 6, 2023 post in Dr. Smith's ECG Blog ).
Significant univariate predictors were included in a forward stepwise logistic regression for outcome of HT, and adjusted odds ratios (aOR) were reported.Results:Of 60 patients, 17 (28.3%) patients had HT. The multivariate model (area under curve = 0.93) had three significant predictors: diabetes mellitus (aOR 36.5,
Circulation: Cardiovascular Quality and Outcomes, Volume 16, Issue 11 , Page e009609, November 1, 2023. P=0.13; 82% versus 75%,P=0.95), diabetes (4.8% Further studies are needed to explore potential pathways between adverse cardiovascular disease outcomes and marijuana use. versus 18.8%,P=0.76; P=0.76; 79.8% versus 77.8%,P=0.75),
Image courtesy: Peerbridge Health christine.book Tue, 12/19/2023 - 10:22 December 19, 2023 — Peerbridge Health has announce the successful completion and findings of its prospective, feasibility clinical trial, resulting in a statistically significant 91.2% Studies estimated that identifying and treating every patient in the U.S.
Introduction:Clinical characteristics of patients with in-hospital onset stroke (IHOS) compared to those with out-of-hospital onset stroke are reported to be late detection of stroke onset, less use of rt-PA, presence of atrial fibrillation, and poor outcome. Patients under 18 years and discharged within 24 hours were excluded.
Background:Post-stroke depression (PSD) is a common neuropsychiatric complication of stroke associated with poor functional outcome and increased mortality. Outcomes were reported as standard mean difference (SMD), and their corresponding 95% confidence interval (95% CI).Results:A to 0.22), p<0.001].
2023, the American Heart Association (AHA) issued a presidential advisory on the urgency of this systemic disorder involving heart disease, kidney disease, diabetes and obesity. The virtual, self-paced Foundations of Cardiometabolic Health Certificate Course is the first step to attaining the CCHP credential.
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundCardiovascular calcification, characterized by deposition of calcium phosphate in the arterial wall and heart valves, is associated with cardiovascular morbidity and mortality and is commonly seen in aging, diabetes, and chronic kidney disease.
Patients with a modified Rankin score of 3-5 were offered enrollment in the Stroke Transitions Program (intervention group). The control group included patients not enrolled in the program. Patients were also provided with the stroke nurses direct contact information to help navigate the healthcare system.
Large vessel occlusion (LVO) is found in 10% of MSS cases and predicts poor neurological outcomes. Descriptive statistics were applied to demographic, clinical, radiographic, and neurological outcomes data, including early neurological deterioration (END) (NIHSS gain 3+).Results:Ninety years old, with 58.8% black, and 16.2%
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. 1,2 The National Institute of Health Stroke Scale (NIHSS) cutoff for poor outcomes is lower in BAO compared to anterior circulation large vessel occlusions (LVO) due to the scale’s weighted scoring towards cortical signs.3,4
We present our institutional experience with EVT in this patient population.Methods:Prospectively maintained database from our comprehensive stroke center was retrospectively reviewed for consecutive cases from December 2014 to July 2023. Difference in 90 day mRS and baseline mRS (delta mRS) was calculated as primary outcome measure.
Written by Jesse McLaren A 75 year-old patient with diabetes and end stage renal disease was sent to the ED after dialysis for three days of nausea, vomiting, loose stool, lightheadedness and fatigue. RR18 sat 99% HR 90 BP 90/60, afebrile. Below is the 15 lead ECG. What do you think? Circulation 2007 2. Khan et al.
The outcome in real-world circumstances is known as ‘Efficacy’ Effectiveness tells us what is possible. What do you think would happen to someone's blood pressure, LDL cholesterol, or blood glucose if you were to evaluate what happens after you stop their blood pressure, cholesterol-lowering, or diabetes medication?
Getty Images milla1cf Fri, 12/08/2023 - 08:17 December 8, 2023 — The American College of Cardiology (ACC) and the American Heart Association (AHA), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrial fibrillation (AFib).
Written by Willy Frick A man in his 50s with a history of hypertension, dyslipidemia, type 2 diabetes mellitus, and prior inferior OMI status post DES to his proximal RCA 3 years prior presented to the emergency department at around 3 AM complaining of chest pain onset around 9 PM the evening prior. Stuckey, T., Zimetbaum, P. Tcheng, J.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionEndoscopic endonasal approach(EEA) techniques have been increasingly utilized and have been associated with development of cerebrospinal fluid(CSF) leak, meningitis, diabetes insipidus post‐operatively. She was discharged home on HD20.ConclusionWe
If you separate those with a significantly elevated Lp(a) (>50mg/dl) and a normal Lp(a) by levels of healthy lifestyle, you see major differences in outcomes. 2023 Sep 15:e14093. Atherosclerosis. 2017 Jan;256:47-52. 2 Healthy lifestyle, lipoprotein (a) levels and the risk of coronary artery disease. Eur J Clin Invest.
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