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Coronaryarterydisease is caused by the retention of a cholesterol particle in the artery wall. But if a retained cholesterol particle is the spark. Insulin resistance and diabetes may not ‘ cause ’ coronaryarterydisease, but they are huge accelerants. Timing Matters.
Small dense lowdensity lipoprotein cholesterol (sdLDLC) is considered as the most atherogenic lipoprotein. Journal of the American Heart Association, Ahead of Print. BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture.
But the goal in this instance is to die after a long and healthy life ‘ with ’ coronaryarterydisease rather than ‘ from ’ coronaryarterydisease. However, the chances of dying from heart disease are directly proportional to the amount of plaque in your coronaryarteries.
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronaryarterydisease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
mmol/l (130 mg/dl) or below, between 20-50% will already have coronaryarterydisease. As HBA1c increases, even in the normal range, the probability of coronaryarterydisease increases. 2023 Nov, 82 (22) 2152–2162. For HBA1c, the trend is similar. So far, two things should be very clear.
mg tablets), together with Caristo Diagnostics , a leading cardiac disease diagnostics company with the novel CaRi-Heart technology to visualize and quantify coronary inflammation, announced today their collaboration to improve awareness and clinical education about the central role of inflammation in coronaryarterydisease.
By age 66, more than half of all females will have evidence of advanced plaque in their coronaryarteries, as seen on a CT calcium score. Subscribe now But are there groups who buck this trend and rarely develop coronaryarterydisease and, by extension, do not die from it early in life? 2023 Jan;19(1):44-55.
When stress is included in the risk factor profile for a future heart attack, it comes in third on the list after abnormal cholesterol and smoking 1. 24% increased risk of coronaryarterydisease. The link is real. For both acute and chronic stress. No real surprise there. Nat Rev Cardiol. 2018 Apr;15(4):215-229.
Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023. The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronaryarterydisease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease.
An elevated Lp(a) is the most common genetic cholesterol disorder impacting 10-20% of the population. Everyone should have an Lp(a) blood test at least once, but this is an absolutely must-do test if you have an early family history of heart disease. Published online August 28, 2023. J Am Coll Cardiol. 2021 Aug 3;78(5):421-433.
An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronaryarterydisease. The occurrence of disease in this instance is probabilistic, not deterministic. An elevated Lp(a) does increase the risk of early cardiovascular disease, but that risk is not set in stone.
(Article will be linked) We know ,HDL carries free cholesterol from peripheral cells, including macrophages and endothelial cells. This is the much famous Reverse Cholesterol Transport(RCT) and the anti-atherosclerotic effect of HDL.It Lipids in Cardiovascular Disease Eduardo Z. HDL : The untold story ! Cardiovasc.
ObjectiveThis study aims to explore the effect of a case management model that breaks through the temporal and spatial characteristics on the at-home phase II exercise rehabilitation of postoperative patients treated with percutaneous coronary intervention (PCI).MethodsWe
Other supplements improved markers such as total cholesterol or triglycerides. While they did improve HDL-C and triglycerides, suggesting an improvement in insulin resistance, the studies that interest me are those with reductions in heart disease mortality, heart attacks and coronaryarterydisease.
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